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2025-05-09 19:15:44, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_024494 2515 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens wingless-type MMTV integration site family, member 2B
(WNT2B), transcript variant WNT-2B2, mRNA.
ACCESSION NM_024494
VERSION NM_024494.2 GI:197333756
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2515)
AUTHORS Wang,H., Fan,L., Xia,X., Rao,Y., Ma,Q., Yang,J., Lu,Y., Wang,C.,
Ma,D. and Huang,X.
TITLE Silencing Wnt2B by siRNA interference inhibits metastasis and
enhances chemotherapy sensitivity in ovarian cancer
JOURNAL Int. J. Gynecol. Cancer 22 (5), 755-761 (2012)
PUBMED 22635028
REMARK GeneRIF: High Wnt2B overexpression is associated with ovarian
cancer metastasis and drug resistance.
REFERENCE 2 (bases 1 to 2515)
AUTHORS Zhang,X., Yang,H., Lee,J.J., Kim,E., Lippman,S.M., Khuri,F.R.,
Spitz,M.R., Lotan,R., Hong,W.K. and Wu,X.
TITLE MicroRNA-related genetic variations as predictors for risk of
second primary tumor and/or recurrence in patients with early-stage
head and neck cancer
JOURNAL Carcinogenesis 31 (12), 2118-2123 (2010)
PUBMED 20819778
REMARK GeneRIF: Observational study of gene-disease association and
gene-gene interaction. (HuGE Navigator)
REFERENCE 3 (bases 1 to 2515)
AUTHORS Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B,
Yusuf S, Gerstein HC, Engert JC and Anand S.
CONSRTM DREAM investigators
TITLE Variation at the NFATC2 locus increases the risk of
thiazolidinedione-induced edema in the Diabetes REduction
Assessment with ramipril and rosiglitazone Medication (DREAM) study
JOURNAL Diabetes Care 33 (10), 2250-2253 (2010)
PUBMED 20628086
REMARK GeneRIF: Observational study of gene-disease association,
gene-environment interaction, and pharmacogenomic / toxicogenomic.
(HuGE Navigator)
REFERENCE 4 (bases 1 to 2515)
AUTHORS Fernandez-Rozadilla C, de Castro L, Clofent J, Brea-Fernandez A,
Bessa X, Abuli A, Andreu M, Jover R, Xicola R, Llor X, Castells A,
Castellvi-Bel S, Carracedo A and Ruiz-Ponte C.
CONSRTM Gastrointestinal Oncology Group of the Spanish Gastroenterological
Association
TITLE Single nucleotide polymorphisms in the Wnt and BMP pathways and
colorectal cancer risk in a Spanish cohort
JOURNAL PLoS ONE 5 (9) (2010)
PUBMED 20844743
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
Publication Status: Online-Only
REFERENCE 5 (bases 1 to 2515)
AUTHORS Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt
TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M,
Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ,
Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S,
Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD,
Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE
and Hingorani AD.
CONSRTM ASCOT investigators; NORDIL investigators; BRIGHT Consortium
TITLE Gene-centric association signals for lipids and apolipoproteins
identified via the HumanCVD BeadChip
JOURNAL Am. J. Hum. Genet. 85 (5), 628-642 (2009)
PUBMED 19913121
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 2515)
AUTHORS Katoh,M., Kirikoshi,H., Saitoh,T., Sagara,N. and Koike,J.
TITLE Alternative splicing of the WNT-2B/WNT-13 gene
JOURNAL Biochem. Biophys. Res. Commun. 275 (1), 209-216 (2000)
PUBMED 10944466
REFERENCE 7 (bases 1 to 2515)
AUTHORS Van Den Berg,D.J., Sharma,A.K., Bruno,E. and Hoffman,R.
TITLE Role of members of the Wnt gene family in human hematopoiesis
JOURNAL Blood 92 (9), 3189-3202 (1998)
PUBMED 9787155
REFERENCE 8 (bases 1 to 2515)
AUTHORS Bergstein,I., Eisenberg,L.M., Bhalerao,J., Jenkins,N.A.,
Copeland,N.G., Osborne,M.P., Bowcock,A.M. and Brown,A.M.
TITLE Isolation of two novel WNT genes, WNT14 and WNT15, one of which
(WNT15) is closely linked to WNT3 on human chromosome 17q21
JOURNAL Genomics 46 (3), 450-458 (1997)
PUBMED 9441749
REFERENCE 9 (bases 1 to 2515)
AUTHORS Katoh,M., Hirai,M., Sugimura,T. and Terada,M.
TITLE Cloning, expression and chromosomal localization of Wnt-13, a novel
member of the Wnt gene family
JOURNAL Oncogene 13 (4), 873-876 (1996)
PUBMED 8761309
REFERENCE 10 (bases 1 to 2515)
AUTHORS Smolich,B.D., McMahon,J.A., McMahon,A.P. and Papkoff,J.
TITLE Wnt family proteins are secreted and associated with the cell
surface
JOURNAL Mol. Biol. Cell 4 (12), 1267-1275 (1993)
PUBMED 8167409
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC141825.1.
On Aug 29, 2008 this sequence version replaced gi:13518020.
Summary: This gene encodes a member of the wingless-type MMTV
integration site (WNT) family of highly conserved, secreted
signaling factors. WNT family members function in a variety of
developmental processes including regulation of cell growth and
differentiation and are characterized by a WNT-core domain. This
gene may play a role in human development as well as human
carcinogenesis. This gene produces two alternatively spliced
transcript variants. [provided by RefSeq, Aug 2008].
Transcript Variant: This variant (WNT-2B2) represents the shorter
transcript yet it encodes the longer protein (isoform WNT-2B2).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC141825.1, AK312696.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025085 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-2515 BC141825.1 1-2515
FEATURES Location/Qualifiers
source 1..2515
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p13"
gene 1..2515
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="wingless-type MMTV integration site family, member
2B"
/db_xref="GeneID:7482"
/db_xref="HGNC:12781"
/db_xref="HPRD:03574"
/db_xref="MIM:601968"
exon 1..697
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 51
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373617635"
variation 116
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:13373888"
variation 361
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:11102484"
variation 405
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145615759"
variation 406
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="g"
/replace="t"
/db_xref="dbSNP:370981921"
variation 412
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148494162"
misc_feature 438..440
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="upstream in-frame stop codon"
STS 497..2034
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/db_xref="UniSTS:486849"
CDS 516..1691
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="isoform WNT-2B2 is encoded by transcript variant
WNT-2B2; XWNT2, Xenopus, homolog of; wingless-type MMTV
integration site family, member 13; protein Wnt-2b"
/codon_start=1
/product="protein Wnt-2b isoform WNT-2B2"
/protein_id="NP_078613.1"
/db_xref="GI:13518021"
/db_xref="CCDS:CCDS847.1"
/db_xref="GeneID:7482"
/db_xref="HGNC:12781"
/db_xref="HPRD:03574"
/db_xref="MIM:601968"
/translation="
MLRPGGAEEAAQLPLRRASAPVPVPSPAAPDGSRASARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFTAARQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT
"
misc_feature 726..1655
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="wnt family; Region: wnt; pfam00110"
/db_xref="CDD:201009"
misc_feature 735..1655
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="found in Wnt-1; Region: WNT1; smart00097"
/db_xref="CDD:128408"
misc_feature 834..1652
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="Region: WNT-core domain"
misc_feature 1362..1364
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/experiment="experimental evidence, no additional details
recorded"
/note="glycosylation site"
variation 540
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:36006679"
variation 557
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="g"
/replace="t"
/db_xref="dbSNP:200421272"
variation 564
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201895225"
variation 567
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3828075"
variation 588
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:374417605"
variation 593
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377064373"
variation 597
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199522950"
exon 698..918
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 716
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377342580"
variation 720
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370244148"
variation 756
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374175549"
variation 775
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:79888517"
variation 777
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199744667"
variation 778
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368523301"
variation 804
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201662450"
variation 817
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140445206"
variation 883
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145011115"
variation 884
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372534893"
variation 893
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142129756"
variation 894
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140255509"
variation 909
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="t"
/db_xref="dbSNP:184557937"
variation 910
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141257308"
exon 919..1196
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 971
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:137855546"
variation 972
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150473635"
variation 974
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202077038"
variation 983
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:116923670"
variation 1006
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149608763"
variation 1028
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189277982"
variation 1039
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373636614"
variation 1054
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:35058556"
variation 1059
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147459875"
variation 1066
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:142716277"
variation 1097
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149716293"
variation 1118
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200972987"
variation 1122
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:351371"
variation 1134
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146253356"
variation 1161
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:372960279"
variation 1183
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="g"
/replace="t"
/db_xref="dbSNP:180824040"
variation 1191
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377518381"
exon 1197..1461
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 1221
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:140289496"
variation 1247
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112638528"
STS 1251..1587
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/standard_name="Wnt2b"
/db_xref="UniSTS:465418"
variation 1273
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375265204"
variation 1290
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201153849"
variation 1331
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="t"
/db_xref="dbSNP:141070301"
variation 1346
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201268308"
variation 1370
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368272752"
variation 1371
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150246330"
variation 1378
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143127439"
STS 1397..1538
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/standard_name="Wnt2b"
/db_xref="UniSTS:466087"
variation 1401
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199991957"
variation 1415
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372397139"
variation 1455
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:138326201"
exon 1462..2470
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 1475
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146027356"
variation 1498
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201658677"
variation 1516
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368029359"
variation 1522
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:192061205"
variation 1532
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371343411"
variation 1552
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201872478"
variation 1564
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:374641766"
variation 1567
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144189370"
variation 1574
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:141296639"
variation 1611
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368700550"
variation 1640
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139266843"
variation 1641
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:111919963"
variation 1648
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:372190907"
variation 1655
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2227860"
variation 1658
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145437043"
variation 1685
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:910697"
variation 1720
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200355523"
variation 1986
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:17030446"
variation 1989
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373531874"
variation 2066
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1569932"
STS 2082..2243
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/standard_name="RH102745"
/db_xref="UniSTS:97079"
variation 2125
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113309659"
variation 2140
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190688758"
variation 2144
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376487188"
variation 2249..2250
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace=""
/replace="at"
/db_xref="dbSNP:139624875"
variation 2310
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143485662"
variation 2331
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2273368"
variation 2372
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181978420"
variation 2377
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184488483"
polyA_signal 2427..2432
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
polyA_site 2445
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
polyA_site 2446
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
variation 2460
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="t"
/db_xref="dbSNP:146289905"
ORIGIN
ggagccgcggcgtcccgtcgcagcgtgcgggagcaggtgggggtgcagcgcggtggcgcgcgggagccccgaggggcggaggcggctgctacacctagggcgtcgcggagcgccccgggcttggcgcgggcggagccgccctaagggccgcgcgtgtccccggcctcggccccgccccgtcccgtccaatgagagcccgcggccgaaggggctgtccgcacactaggcccgcagctcccttcagcgccgcagaccccctgacaccgcacccggtcctcaggcagcgcgccccagaccccgggttcggcacgccgtcgtcggcttccggacatcgcaacttgcgcccctctcggggatcctcctcccgggctctggaccccaggtgatcctaggtccccagccgccggcgaacaccatggccccccaggggggtgaggtaggagcagcctgagtacccccagaaggtgccccgtccacgcccctccgggctgcgcggcgggagtcttcggggagctatgctgagaccgggtggtgcggaggaagctgcgcagctcccgcttcggcgcgccagcgccccggtccctgtgccgtcgcccgcggcccccgacggctcccgggcttcggcccgcctaggtcttgcctgccttctgctcctgctgctgctgacgctgccggcccgcgtagacacgtcctggtggtacattggggcactgggggcacgagtgatctgtgacaatatccctggtttggtgagccggcagcggcagctgtgccagcgttacccagacatcatgcgttcagtgggcgagggtgcccgagaatggatccgagagtgtcagcaccaattccgccaccaccgctggaactgtaccaccctggaccgggaccacaccgtctttggccgtgtcatgctcagaagtagccgagaggcagcttttgtatatgccatctcatcagcaggggtagtccacgctattactcgcgcctgtagccagggtgaactgagtgtgtgcagctgtgacccctacacccgtggccgacaccatgaccagcgtggggactttgactggggtggctgcagtgacaacatccactacggtgtccgttttgccaaggccttcgtggatgccaaggagaagaggcttaaggatgcccgggccctcatgaacttacataataaccgctgtggtcgcacggctgtgcggcggtttctgaagctggagtgtaagtgccatggcgtgagtggttcctgtactctgcgcacctgctggcgtgcactctcagatttccgccgcacaggtgattacctgcggcgacgctatgatggggctgtgcaggtgatggccacccaagatggtgccaacttcaccgcagcccgccaaggctatcgccgtgccacccggactgatcttgtctactttgacaactctccagattactgtgtcttggacaaggctgcaggttccctaggcactgcaggccgtgtctgcagcaagacatcaaaaggaacagacggttgtgaaatcatgtgctgtggccgagggtacgacacaactcgagtcacccgtgttacccagtgtgagtgcaaattccactggtgctgtgctgtacggtgcaaggaatgcagaaatactgtggacgtccatacttgcaaagcccccaagaaggcagagtggctggaccaaacctgaacacacagatacctcactcatccctccaattcaagcctctcaactcaaaagcacaagatccttgcatgcacaccttcctccaccctccaccctgggctgctaccgcttctatttaaggatgtagagagtaatccatagggaccatggtgtcctggctggttccttagccctgggaaggagttgtcaggggatataagaaactgagcaagctccctgatttcccgctctggagatttgaagggagagtagaagagatagggggtctttagagtgaaatgagttgcactaaagtacgtagttgaggctccttttttctttcctttgcaccagcttcccgatacttcttggtgtgcaagaggaagggtacctgtagagagcttctttttgtttctacctggccaaagttagatgggacaaagatgaatggcatgtcccttctctgaagtccgtttgagcagaactacctggtaccccgaaagaaaatcttaggctaccacattctattattgagagcctgagatgttagccatagtggacaaggttccattcacatgctcatatgtttataaactgtgttttgtagaagaaaaagaatcataacaatacaaacacacattcattctctctttttctctctaccattctcaacctgtattggacagcactgcctcttttgcttacttgctgcctgttcaaactgaggtggaatgcagtggttcccatgcttaacaaatcattaaaacaccctagaacactcctaggatagattaatgtagtaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:7482 -> Molecular function: GO:0005109 [frizzled binding] evidence: IBA
GeneID:7482 -> Biological process: GO:0002062 [chondrocyte differentiation] evidence: IEP
GeneID:7482 -> Biological process: GO:0002088 [lens development in camera-type eye] evidence: ISS
GeneID:7482 -> Biological process: GO:0008584 [male gonad development] evidence: IEP
GeneID:7482 -> Biological process: GO:0016055 [Wnt receptor signaling pathway] evidence: IMP
GeneID:7482 -> Biological process: GO:0021871 [forebrain regionalization] evidence: IEP
GeneID:7482 -> Biological process: GO:0030182 [neuron differentiation] evidence: IBA
GeneID:7482 -> Biological process: GO:0030182 [neuron differentiation] evidence: ISS
GeneID:7482 -> Biological process: GO:0045165 [cell fate commitment] evidence: IBA
GeneID:7482 -> Biological process: GO:0060070 [canonical Wnt receptor signaling pathway] evidence: IEA
GeneID:7482 -> Biological process: GO:0060492 [lung induction] evidence: IEA
GeneID:7482 -> Biological process: GO:0060638 [mesenchymal-epithelial cell signaling] evidence: IEA
GeneID:7482 -> Biological process: GO:0061072 [iris morphogenesis] evidence: ISS
GeneID:7482 -> Biological process: GO:0061303 [cornea development in camera-type eye] evidence: ISS
GeneID:7482 -> Biological process: GO:0071425 [hematopoietic stem cell proliferation] evidence: IDA
GeneID:7482 -> Biological process: GO:0090190 [positive regulation of branching involved in ureteric bud morphogenesis] evidence: IEA
GeneID:7482 -> Biological process: GO:0090263 [positive regulation of canonical Wnt receptor signaling pathway] evidence: IDA
GeneID:7482 -> Cellular component: GO:0005576 [extracellular region] evidence: TAS
GeneID:7482 -> Cellular component: GO:0005578 [proteinaceous extracellular matrix] evidence: IEA
GeneID:7482 -> Cellular component: GO:0005615 [extracellular space] evidence: NAS
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DBCLS
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