Home |
Help |
Advanced search
2025-05-09 19:30:09, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_012199 7478 bp mRNA linear PRI 02-JUN-2013
DEFINITION Homo sapiens argonaute RISC catalytic component 1 (AGO1), mRNA.
ACCESSION NM_012199
VERSION NM_012199.2 GI:29171732
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7478)
AUTHORS Chen,Z., Lai,T.C., Jan,Y.H., Lin,F.M., Wang,W.C., Xiao,H.,
Wang,Y.T., Sun,W., Cui,X., Li,Y.S., Fang,T., Zhao,H.,
Padmanabhan,C., Sun,R., Wang,D.L., Jin,H., Chau,G.Y., Huang,H.D.,
Hsiao,M. and Shyy,J.Y.
TITLE Hypoxia-responsive miRNAs target argonaute 1 to promote
angiogenesis
JOURNAL J. Clin. Invest. 123 (3), 1057-1067 (2013)
PUBMED 23426184
REMARK GeneRIF: Tumor xenografts and human cancer specimens indicate that
AGO1-mediated translational desuppression of VEGF may be associated
with tumor angiogenesis and poor prognosis.
REFERENCE 2 (bases 1 to 7478)
AUTHORS Janas,M.M., Wang,B., Harris,A.S., Aguiar,M., Shaffer,J.M.,
Subrahmanyam,Y.V., Behlke,M.A., Wucherpfennig,K.W., Gygi,S.P.,
Gagnon,E. and Novina,C.D.
TITLE Alternative RISC assembly: binding and repression of microRNA-mRNA
duplexes by human Ago proteins
JOURNAL RNA 18 (11), 2041-2055 (2012)
PUBMED 23019594
REMARK GeneRIF: Ago2 and Ago1 can slice, and thus functionally bind,
preannealed siRNA-mRNA duplexes.
Erratum:[RNA. 2012 Dec;18(12):2345]
REFERENCE 3 (bases 1 to 7478)
AUTHORS Vaksman,O., Hetland,T.E., Trope',C.G., Reich,R. and Davidson,B.
TITLE Argonaute, Dicer, and Drosha are up-regulated along tumor
progression in serous ovarian carcinoma
JOURNAL Hum. Pathol. 43 (11), 2062-2069 (2012)
PUBMED 22647351
REMARK GeneRIF: Drosha, Dicer, Argonaute 1, and Argonaute 2 are
differentially expressed at different metastatic sites in ovarian
carcinoma compared with primary carcinomas.
REFERENCE 4 (bases 1 to 7478)
AUTHORS Ameyar-Zazoua,M., Rachez,C., Souidi,M., Robin,P., Fritsch,L.,
Young,R., Morozova,N., Fenouil,R., Descostes,N., Andrau,J.C.,
Mathieu,J., Hamiche,A., Ait-Si-Ali,S., Muchardt,C., Batsche,E. and
Harel-Bellan,A.
TITLE Argonaute proteins couple chromatin silencing to alternative
splicing
JOURNAL Nat. Struct. Mol. Biol. 19 (10), 998-1004 (2012)
PUBMED 22961379
REMARK GeneRIF: AGO1 and AGO2 proteins couple RNA polymerase II elongation
to chromatin modification
REFERENCE 5 (bases 1 to 7478)
AUTHORS Turchinovich,A. and Burwinkel,B.
TITLE Distinct AGO1 and AGO2 associated miRNA profiles in human cells and
blood plasma
JOURNAL RNA Biol 9 (8), 1066-1075 (2012)
PUBMED 22858679
REMARK GeneRIF: Study observed a dramatic difference in AGO1 and AGO2
associated miRNA profiles in blood plasma. The lack of correlation
between AGO1 and AGO2 miRNA content in the plasma can be explained
by the fact that many tissues contribute to the extracellular miRNA
content.
REFERENCE 6 (bases 1 to 7478)
AUTHORS Doi,N., Zenno,S., Ueda,R., Ohki-Hamazaki,H., Ui-Tei,K. and Saigo,K.
TITLE Short-interfering-RNA-mediated gene silencing in mammalian cells
requires Dicer and eIF2C translation initiation factors
JOURNAL Curr. Biol. 13 (1), 41-46 (2003)
PUBMED 12526743
REFERENCE 7 (bases 1 to 7478)
AUTHORS Carmell,M.A., Xuan,Z., Zhang,M.Q. and Hannon,G.J.
TITLE The Argonaute family: tentacles that reach into RNAi, developmental
control, stem cell maintenance, and tumorigenesis
JOURNAL Genes Dev. 16 (21), 2733-2742 (2002)
PUBMED 12414724
REMARK Review article
REFERENCE 8 (bases 1 to 7478)
AUTHORS Martinez,J., Patkaniowska,A., Urlaub,H., Luhrmann,R. and Tuschl,T.
TITLE Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
JOURNAL Cell 110 (5), 563-574 (2002)
PUBMED 12230974
REFERENCE 9 (bases 1 to 7478)
AUTHORS Koesters,R., Adams,V., Betts,D., Moos,R., Schmid,M., Siermann,A.,
Hassam,S., Weitz,S., Lichter,P., Heitz,P.U., von Knebel
Doeberitz,M. and Briner,J.
TITLE Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence,
genomic organization, localization to chromosomal bands 1p34-p35,
and expression
JOURNAL Genomics 61 (2), 210-218 (1999)
PUBMED 10534406
REFERENCE 10 (bases 1 to 7478)
AUTHORS Reddy,P.H., Stockburger,E., Gillevet,P. and Tagle,D.A.
TITLE Mapping and characterization of novel (CAG)n repeat cDNAs from
adult human brain derived by the oligo capture method
JOURNAL Genomics 46 (2), 174-182 (1997)
PUBMED 9417904
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AF093097.1.
On Mar 25, 2003 this sequence version replaced gi:6912351.
Summary: This gene encodes a member of the Argonaute family of
proteins which play a role in RNA interference. The encoded protein
is highly basic, and contains a PAZ domain and a PIWI domain. It
may interact with dicer1 and play a role in
short-interfering-RNA-mediated gene silencing. This gene is located
on chromosome 1 in a cluster of closely related family members
including argonaute 3, and argonaute 4. [provided by RefSeq, Jul
2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF093097.1, BC063275.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
FEATURES Location/Qualifiers
source 1..7478
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p34.3"
gene 1..7478
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="argonaute RISC catalytic component 1"
/db_xref="GeneID:26523"
/db_xref="HGNC:3262"
/db_xref="HPRD:06942"
/db_xref="MIM:606228"
exon 1..238
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
misc_feature 100..102
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="upstream in-frame stop codon"
variation 163
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:376952387"
variation 181
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:374168686"
variation 194
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:377185293"
variation 195
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:369200771"
variation 198
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:369830249"
CDS 214..2787
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="argonaute 1; Golgi Endoplasmic Reticulum protein 95
kDa; putative RNA-binding protein Q99; hAgo1; eIF2C 1;
eIF-2C 1; argonaute1; eukaryotic translation initiation
factor 2C, 1"
/codon_start=1
/product="protein argonaute-1"
/protein_id="NP_036331.1"
/db_xref="GI:6912352"
/db_xref="CCDS:CCDS398.1"
/db_xref="GeneID:26523"
/db_xref="HGNC:3262"
/db_xref="HPRD:06942"
/db_xref="MIM:606228"
/translation="
MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA
"
misc_feature 289..2781
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="protein argonaute; Provisional; Region: PLN03202"
/db_xref="CDD:215631"
misc_feature 730..888
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="Domain of unknown function (DUF1785); Region:
DUF1785; pfam08699"
/db_xref="CDD:219976"
misc_feature 886..1248
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="PAZ domain, argonaute_like subfamily. Argonaute is
part of the RNA-induced silencing complex (RISC), and is
an endonuclease that plays a key role in the RNA
interference pathway. The PAZ domain has been named after
the proteins Piwi,Argonaut, and Zwille; Region:
PAZ_argonaute_like; cd02846"
/db_xref="CDD:239212"
misc_feature order(1042..1044,1087..1089,1129..1131,1141..1143,
1195..1197,1216..1218,1222..1224)
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="nucleic acid-binding interface [nucleotide
binding]; other site"
/db_xref="CDD:239212"
misc_feature 1381..2658
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="Piwi_ago-like: PIWI domain, Argonaute-like
subfamily. Argonaute is the central component of the
RNA-induced silencing complex (RISC) and related
complexes. The PIWI domain is the C-terminal portion of
Argonaute and consists of two subdomains, one of...;
Region: Piwi_ago-like; cd04657"
/db_xref="CDD:240015"
misc_feature order(1792..1794,1804..1806,1840..1851,1858..1860,
1882..1884,1891..1893,1903..1905,1915..1917)
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="5' RNA guide strand anchoring site; other site"
/db_xref="CDD:240015"
misc_feature order(1996..1998,2002..2004,2212..2214,2626..2628)
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/note="active site"
/db_xref="CDD:240015"
exon 239..422
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 241
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:12746607"
variation 242
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:146814747"
variation 245
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:144077445"
variation 246
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:140869088"
variation 261
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:202083240"
variation 264
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:138410930"
variation 273
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:79428335"
variation 274
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:75289061"
variation 276
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:76388453"
variation 349
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:199891800"
variation 361
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:146957455"
variation 363
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:200988923"
variation 378
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:143228790"
variation 396
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:74665168"
variation 412
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:200676269"
variation 420
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:375999904"
exon 423..543
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 518
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:368596181"
variation 538
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:371043471"
exon 544..725
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 645
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:140048484"
variation 678
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:146336392"
variation 715
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:200107860"
exon 726..862
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 742
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:369913779"
exon 863..997
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 867
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:11806527"
variation 870
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:11811275"
variation 894
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:2296470"
variation 908
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:372933409"
variation 915
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:201138355"
variation 937
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:17855789"
exon 998..1085
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 1000
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="c"
/db_xref="dbSNP:34232554"
variation 1044
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:372555392"
exon 1086..1233
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 1092
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:189586551"
variation 1116
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:372979737"
variation 1227
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:149082767"
variation 1228
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:151208943"
exon 1234..1353
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 1243
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:200563862"
variation 1293
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:199616208"
exon 1354..1476
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 1386
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:72661614"
variation 1448
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:376308772"
variation 1449
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:377394072"
variation 1452
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:142094247"
variation 1470
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:61751003"
exon 1477..1610
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 1497
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:199936275"
variation 1553
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:371917876"
variation 1572
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:375102195"
exon 1611..1795
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 1637
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:12739932"
variation 1692
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="t"
/db_xref="dbSNP:12735795"
variation 1694
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="t"
/db_xref="dbSNP:12735796"
variation 1695
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:368806171"
variation 1720
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:201120683"
variation 1739
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:143395835"
variation 1742
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="t"
/db_xref="dbSNP:200447801"
variation 1752
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:371346774"
exon 1796..1955
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 1839
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:199790587"
variation 1860
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:141975081"
variation 1911
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:139495925"
exon 1956..2046
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 2010
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:150639776"
variation 2012..2013
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="c"
/db_xref="dbSNP:35257283"
variation 2013
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:149707892"
variation 2038
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:201807040"
exon 2047..2241
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 2069
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:72661618"
variation 2136
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:148568098"
variation 2193
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:147571046"
variation 2222
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:12564106"
exon 2242..2376
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 2260
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:143104504"
variation 2301
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:7512720"
variation 2323
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:142277966"
variation 2325
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:138262926"
exon 2377..2478
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 2384
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:373512212"
variation 2457
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:370393930"
exon 2479..2678
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 2525
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:371456175"
variation 2578
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:144290045"
variation 2619
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:139104482"
exon 2679..7478
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/inference="alignment:Splign:1.39.8"
variation 2695
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:200112017"
variation 2742
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:367549238"
variation 2764
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:371427797"
variation 2832
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:376748083"
variation 2928
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:150023314"
variation 2963
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:372514513"
variation 3038
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:202115790"
variation 3060
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:181957464"
variation 3101
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:187653963"
variation 3230
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:190778316"
STS 3256..4153
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="EIF2C1_v617"
/db_xref="UniSTS:462177"
variation 3317
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:116130930"
variation 3333
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:16822444"
variation 3395
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:181016113"
variation 3403
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:2057606"
variation 3539
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:369176195"
variation 3618
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:372299339"
variation 3646
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:11263836"
STS 3789..3949
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="RH104023"
/db_xref="UniSTS:98348"
variation 3924..3925
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="tt"
/db_xref="dbSNP:377610395"
variation 3956
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:11544095"
variation 4082
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:372998612"
variation 4092
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:373319406"
polyA_signal 4115..4120
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
polyA_site 4140
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
variation 4266
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:376079873"
variation 4463..4464
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="t"
/db_xref="dbSNP:34158936"
variation 4484
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:78160010"
variation 4486
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:80323450"
variation 4535
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:185636267"
variation 4555
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:141020163"
variation 4637
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:3767701"
variation 4729
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:11263837"
variation 4757
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:147872657"
variation 4892
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:374604719"
variation 4986
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:148920115"
variation 5217
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:142820733"
variation 5233
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:11584551"
variation 5367
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:190099919"
variation 5388
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:182744550"
variation 5427
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:151051297"
STS 5444..5544
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="SHGC-74590"
/db_xref="UniSTS:23542"
variation 5547
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:187348990"
STS 5599..5843
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="L18179"
/db_xref="UniSTS:74381"
variation 5626..5627
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="t"
/db_xref="dbSNP:368600514"
variation 5659
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:41308339"
variation 5770
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:191912446"
variation 5778..5781
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="gcct"
/db_xref="dbSNP:372569339"
variation 5779..5786
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="cctgcctg"
/db_xref="dbSNP:372821782"
variation 5808..5811
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="ctgt"
/db_xref="dbSNP:200133723"
variation 5811
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:112770520"
variation 6076
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:72661619"
variation 6077
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:150347120"
variation 6114
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:192229737"
variation 6188
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:368046981"
variation 6294
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:138074007"
variation 6353
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:141089342"
variation 6380
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:144915813"
variation 6393
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:374706238"
variation 6394
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:113615155"
variation 6432
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:114256824"
variation 6437
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:184309288"
variation 6465
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace=""
/replace="t"
/db_xref="dbSNP:370557448"
variation 6583
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:78530614"
variation 6775
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:138767681"
variation 6859
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="t"
/db_xref="dbSNP:371613930"
variation 6865
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:10159166"
variation 6889
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:373746606"
variation 6905
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="c"
/replace="g"
/db_xref="dbSNP:375483845"
STS 6946..7093
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="SHGC-74594"
/db_xref="UniSTS:27796"
variation 7149
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="t"
/db_xref="dbSNP:186734072"
STS 7215..7463
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="A006G35"
/db_xref="UniSTS:10693"
STS 7215..7463
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="G20793"
/db_xref="UniSTS:10692"
STS 7342..7475
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/standard_name="G64298"
/db_xref="UniSTS:158654"
variation 7408
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="g"
/db_xref="dbSNP:149237486"
variation 7412
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:144443110"
polyA_signal 7449..7454
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
variation 7461
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:191490961"
variation 7464
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="g"
/replace="t"
/db_xref="dbSNP:147996549"
polyA_site 7478
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/experiment="experimental evidence, no additional details
recorded"
variation 7478
/gene="AGO1"
/gene_synonym="EIF2C; EIF2C1; GERP95; Q99"
/replace="a"
/replace="c"
/db_xref="dbSNP:184023415"
ORIGIN
actggcagctggccgggcgctcgcagtgggagctgctgcaggctccgcggcggcggcaacggaggctgcgggggcggcggcgcgagcggccgggcttggtaggggagccgagcccggcccgggatcccgagcagcgagagtgtggggtacctaggcccctcacgctggacttcacagtctccgggccgcctgacctccgcacgggtatatgggatggaagcgggaccctcgggagcagctgcgggcgcttacctgccccccctgcagcaggtgttccaggcacctcgccggcctggcattggcactgtggggaaaccaatcaagctcctggccaattactttgaggtggacatccctaagatcgacgtgtaccactacgaggtggacatcaagccggataagtgtccccgtagagtcaaccgggaagtggtggaatacatggtccagcatttcaagcctcagatctttggtgatcgcaagcctgtgtatgatggaaagaagaacatttacactgtcacagcactgcccattggcaacgaacgggtcgactttgaggtgacaatccctggggaagggaaggatcgaatctttaaggtctccatcaagtggctagccattgtgagctggcgaatgctgcatgaggccctggtcagcggccagatccctgttcccttggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttttataaggcacagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaagcccctcacggactctcagcgcgttcgcttcaccaaggagatcaagggcctgaaggtggaagtcacccactgtggacagatgaagaggaagtaccgcgtgtgtaatgttacccgtcgccctgctagccatcagacattccccttacagctggagagtggacagactgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccatctgccctgcctacaagttggccaggaacaaaagcatacctaccttcccctagaggtctgtaacattgtggctgggcagcgctgtattaaaaagctgaccgacaaccagacctcgaccatgataaaggccacagctagatccgctccagacagacaggaggagatcagtcgcctgatgaagaatgccagctacaacttagatccctacatccaggaatttgggatcaaagtgaaggatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccggaaccgggccattgccacacccaatcagggtgtctgggacatgcgggggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcggggatgcctatccagggtcaaccttgtttctgcaaatatgcacagggggcagacagcgtggagcctatgttccggcatctcaagaacacctactcagggctgcagctcattattgtcatcctgccagggaagacgccggtgtatgctgaggtgaaacgtgtcggagatacactcttgggaatggctacgcagtgtgtgcaggtgaagaacgtggtcaagacctcacctcagactctgtccaacctctgcctcaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgccgtttttcaacagccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtggtaggcagtatggatgcccaccccagccgatactgtgctactgtgcgggtacagcgaccacggcaagagatcattgaagacttgtcctacatggtgcgtgagctcctcatccaattctacaagtccacccgtttcaagcctacccgcatcatcttctaccgagatggggtgcctgaaggccagctaccccagatactccactatgagctactggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttatattgtggtgcagaaacgccatcacacccgccttttctgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccacagtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagccgaccatcccattactatgttctttgggatgacaaccgtttcacagcagatgagctccagatcctgacgtaccagctgtgccacacttacgtacgatgcacacgctctgtctctatcccagcacctgcctactatgcccgcctggtggctttccgggcacgataccacctggtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaggagctgtgccacccaaatccagaggaagcaaggaggagggaggtggggtagggaggagtgtaggatgccttgtttccttctatagaggtggtgtaagagtggggaacagggccagcaagacagaccaccagccagaaatctctgatatcaacctcatgtcccccacccctcaccccatcttgtcacatctggccctgaccccactggaccaaaaggggcagcactggtgcccaccatacacacaggtgtctcatgtgactcacagtgctaaagactcatgcttgacagcttggtaaggtcaactctgtagccctgcagacaaaagctggttaggtttgggtttgatactttagatgggaaagtgaggggcttgagaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggactagatttgtttaagaagaaaaatgaaaccagacccagatcaatattttaggatactagatgttttaatgggttcagaatccagtttgtaggaagattttttaatggttttggttgctcctcccccagctgccaccccccaccttacccttattcctctctgtccacattttctgccccaccttacttctcctccctgacagacatccagcccctagtaatacttaaggcactatggcacttagctttgaagtgacacgaccctgtcttccttccgcccgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttctttggggaatggggtgggggtgggagaggaggtagatggggaagaaataccccagacccaacaaacctccagccagaaagccagctattttgcatttgaaggaattgacttcctcattcattgagctttttaaaagatcacaacctcaagatggttaaaatccattgacatttgcactttcaaacatgacaagtctcggagctgctgagatgacaggcccctggcctttccacttatgcctccttttctccttattcctcctacctcccgccccgcccaggtctggagttactttcatagcatttttcactcttggcttcttttctcccttgatggtcaagtctcttatgtttcaatatttcttaactggggtgtcttataacaaaaaactcttaggtctaaaatgagaaaaaagagagaaaacaaaatgttatttttataccataacttgagtgtattgccaaaatttggaaatccttcccatgcctgatgagtttatatcccagaaacattgagccatcagaatgaactgtgtacctgatttgttctctgacctggctaggtagggagggggtggttatcgccccaagatggggtccaggctccatccttcctctgtgcagataatacctttttcttgctatagcctccctcctctgcactgtcctgcactctttcttgcaagtgcatctttttccttcccctggactgtcctctgaccctttggctcatcctagattgcagtgtgtcctgtggacaggctggggaattttgctgctccctattgcttctgtttacaaaaatgaatttttcctggtttcccactagggcatgtgggtgggtggcatggacttttttttttttttttttttgtcttgagacatggggtttggctgtcttgcaggactggagaaggtggtggttctagcttggtctctgttggccttgaagcaagcatcccccctgccctttttccttgactgttcatttttttcctgccccactgcttgggatggggagttgcaacttcagtgtggaatttcctctttgaggagcctgggcttggatctatcctgatctggtgatgaagccatgattactttagacctagcccaggcttggaggccagctggaggaagaagggtctaaatcctggcctgtagagttagaactaccatttcctccccttagctgcccttgtatgacccggatttgctatgcaaaacaatctatcccaggttctgttctggttggctacattgttcagcaactcacaaaacgtagcacaaacattcattatggagaaagcatcaggactgttgagtaactcctcctttacttttttcctgctggctacagcatggggtgccctataggcacaagcccagctgaagaacagaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgctaacactccatctgccctgtccattgccttcatatacagtctacttcgtgttctgtcaccctttggggaggggagttctcctgggacagtgggctctgcatgttctccacttggatacattttggggctaggatcagggcactattcctggagggtccagtcattcaccagcatttgcaaatgtccatagggagcaggtggcagcctctactcccagcaacaagtttgtgttctctccttttctctctttgcctcactctctccagttggttttcagctggggcttgaaatgcatttttagccctttgacgtggcttatgccattcaagaaataaaaagcaagagaatcagctttgggcaatgacaagaaatgagttcttactctgatttttttgtaaaaagataatttttgagacttgaaaaataccccgaccttgagattattcctgtttgaaaggtggtgcatgcagatggagaagtggtgttggcagcaagctttggctcatgtggatttggtttaagtggtgcttcttacccaagcttcaaggaagtgcttgggggacccccagcctcatcctcttagttgggtctcttgttccctttgtaccactgttttgccttccttttcctcttctctctttgcctggcttcctttcccttttcttctattcactctgcttgcttgctggccggcctgcctgcctgcctgcctgcctgcctgcctgtctgcctatgtgatgatgaaatctctgcatggctgcaatgatcccactgttagctggcagggtcaggcttagctccttgactgcagaagaccaagaacctgttccccaagcccagagatgtccacctgggctggactgccctcaagcttatactagagaagagcaactgacctgcccaacttgtgtgaagtcaggagggtttctggcattttccacacctgtccactccttggagctggtttctctcattgctttttctaaatctggttctttttctctttacctggggcctggcttttctgagattgtcttagggttgagctatttgggtatcctgggtttgagtgttaggggatggacataaaggaaaaagagtgatgagaagagaatggagagaatttgaataaaaggtgggaaaggagagcactgttctttgattgtttatccagtccaacctgatccattagggatcgaggtgctacactggcctccagggataagcctggggctactgttgctgggaacttaggcttaacataaagccgaagaaggtacctagaaatttgaaacttccctaaaaagctcctaatgcccacctgctagatagcttctctgtggcctcctatttagctaagcagcagtgtttttggatactttttttttctgtttgtgaataaggccagcactcaagatgggcagccaagggtgcactgactattagctggcccataggatatctgtaaggctggtgggacagttttggacctggaatcatgtgtaactaacaaggttggacgtttcttccccatcagggtagaaaaatcatctcaaactagccaaaaggcagttttggaaactacattgggggacgttatttttatttatatatggggcctaggccaatccaggatggtagctggaataccttccttcttaaaatctgatcatggcagggatatgcagggcactttttactatttggccttctaagcagattgggaaggaggtattttctggttttcgctttcctccgacttaataggacttgccttctccctgggcagggagagaggctgggttggtgctctcccttactctactcatactgacttagagcctctggctgctgtttgggcatccaagaaagggaggggaaggaatgagctaaaaacaaaacagaatgaggtgggaaagggagattttcttctttacagaggaaaataggaaaccctccaagaattgtgcaagtaaagacatttgttgaatgcactgagtcccttggtgtagtagcaataaggaaaaatgaaattactttcctgtgcacacagtccagcctaattggtatgtgatgttgcacttagcagccatgtggtgggcatgtgtgactactctggttttcactttagtttctaaactttttatccctctcaagtccagcatggatggggaaatgtctctggatccccacagctgtgtacttgtttgcatttgtttccctttgagatttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtgaaattatcccagcagctgtaatgtacagttccttctgaagcaagcaacatcagcagcagcagcagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:26523 -> Molecular function: GO:0003723 [RNA binding] evidence: IEA
GeneID:26523 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:26523 -> Biological process: GO:0000956 [nuclear-transcribed mRNA catabolic process] evidence: IDA
GeneID:26523 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:26523 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
GeneID:26523 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
GeneID:26523 -> Biological process: GO:0007219 [Notch signaling pathway] evidence: TAS
GeneID:26523 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
GeneID:26523 -> Biological process: GO:0010467 [gene expression] evidence: TAS
GeneID:26523 -> Biological process: GO:0035278 [negative regulation of translation involved in gene silencing by miRNA] evidence: IDA
GeneID:26523 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:26523 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:26523 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:26523 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: TAS
GeneID:26523 -> Cellular component: GO:0000932 [cytoplasmic mRNA processing body] evidence: IEA
GeneID:26523 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:26523 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:26523 -> Cellular component: GO:0005844 [polysome] evidence: IDA
GeneID:26523 -> Cellular component: GO:0030529 [ribonucleoprotein complex] evidence: IDA
GeneID:26523 -> Cellular component: GO:0035068 [micro-ribonucleoprotein complex] evidence: IDA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.