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2025-05-09 19:10:36, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_005646 5130 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens TAR (HIV-1) RNA binding protein 1 (TARBP1), mRNA.
ACCESSION NM_005646
VERSION NM_005646.3 GI:110825987
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5130)
AUTHORS Sand,M., Skrygan,M., Georgas,D., Arenz,C., Gambichler,T., Sand,D.,
Altmeyer,P. and Bechara,F.G.
TITLE Expression levels of the microRNA maturing microprocessor complex
component DGCR8 and the RNA-induced silencing complex (RISC)
components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in
epithelial skin cancer
JOURNAL Mol. Carcinog. 51 (11), 916-922 (2012)
PUBMED 22025453
REMARK GeneRIF: DGCR8, AGO1, AGO2, PACT, and TARBP1 expression levels were
significantly higher in the epithelial skin cancer groups than the
healthy controls (P > 0.05).
REFERENCE 2 (bases 1 to 5130)
AUTHORS Daniels,S.M., Melendez-Pena,C.E., Scarborough,R.J., Daher,A.,
Christensen,H.S., El Far,M., Purcell,D.F., Laine,S. and Gatignol,A.
TITLE Characterization of the TRBP domain required for dicer interaction
and function in RNA interference
JOURNAL BMC Mol. Biol. 10, 38 (2009)
PUBMED 19422693
REMARK GeneRIF: Binding of Dicer to TRBPs is critical for RNAi function.
Publication Status: Online-Only
REFERENCE 3 (bases 1 to 5130)
AUTHORS Wu,H., Min,J., Zeng,H. and Plotnikov,A.N.
TITLE Crystal structure of the methyltransferase domain of human TARBP1
JOURNAL Proteins 72 (1), 519-525 (2008)
PUBMED 18412263
REMARK GeneRIF: The crystal structure of methyltransferase domain of human
TARBP1 protein in complex with S-adenosyl-L-homocysteine (AdoHcy)
at 1.6-A resolution, is reported.
REFERENCE 4 (bases 1 to 5130)
AUTHORS Seshadri,S., DeStefano,A.L., Au,R., Massaro,J.M., Beiser,A.S.,
Kelly-Hayes,M., Kase,C.S., D'Agostino,R.B. Sr., Decarli,C.,
Atwood,L.D. and Wolf,P.A.
TITLE Genetic correlates of brain aging on MRI and cognitive test
measures: a genome-wide association and linkage analysis in the
Framingham Study
JOURNAL BMC Med. Genet. 8 (SUPPL 1), S15 (2007)
PUBMED 17903297
REMARK Publication Status: Online-Only
REFERENCE 5 (bases 1 to 5130)
AUTHORS Yedavalli,V.S., Benkirane,M. and Jeang,K.T.
TITLE Tat and trans-activation-responsive (TAR) RNA-independent induction
of HIV-1 long terminal repeat by human and murine cyclin T1
requires Sp1
JOURNAL J. Biol. Chem. 278 (8), 6404-6410 (2003)
PUBMED 12458222
REMARK GeneRIF: induces induction of HIV-1 long terminal repeat by human
and murine cyclin T1 and requires Sp1.
REFERENCE 6 (bases 1 to 5130)
AUTHORS Wu-Baer,F., Lane,W.S. and Gaynor,R.B.
TITLE Identification of a group of cellular cofactors that stimulate the
binding of RNA polymerase II and TRP-185 to human immunodeficiency
virus 1 TAR RNA
JOURNAL J. Biol. Chem. 271 (8), 4201-4208 (1996)
PUBMED 8626763
REFERENCE 7 (bases 1 to 5130)
AUTHORS Wu-Baer,F., Lane,W.S. and Gaynor,R.B.
TITLE The cellular factor TRP-185 regulates RNA polymerase II binding to
HIV-1 TAR RNA
JOURNAL EMBO J. 14 (23), 5995-6009 (1995)
PUBMED 8846792
REFERENCE 8 (bases 1 to 5130)
AUTHORS Wu-Baer,F., Sigman,D. and Gaynor,R.B.
TITLE Specific binding of RNA polymerase II to the human immunodeficiency
virus trans-activating region RNA is regulated by cellular
cofactors and Tat
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92 (16), 7153-7157 (1995)
PUBMED 7638159
REFERENCE 9 (bases 1 to 5130)
AUTHORS Sheline,C.T., Milocco,L.H. and Jones,K.A.
TITLE Two distinct nuclear transcription factors recognize loop and bulge
residues of the HIV-1 TAR RNA hairpin
JOURNAL Genes Dev. 5 (12B), 2508-2520 (1991)
PUBMED 1752441
REFERENCE 10 (bases 1 to 5130)
AUTHORS Wu,F., Garcia,J., Sigman,D. and Gaynor,R.
TITLE tat regulates binding of the human immunodeficiency virus
trans-activating region RNA loop-binding protein TRP-185
JOURNAL Genes Dev. 5 (11), 2128-2140 (1991)
PUBMED 1936997
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from U38847.1, AL136124.10 and
AL355472.19.
On Jul 28, 2006 this sequence version replaced gi:19743835.
Summary: HIV-1, the causative agent of acquired immunodeficiency
syndrome (AIDS), contains an RNA genome that produces a
chromosomally integrated DNA during the replicative cycle.
Activation of HIV-1 gene expression by the transactivator Tat is
dependent on an RNA regulatory element (TAR) located downstream of
the transcription initiation site. This element forms a stable
stem-loop structure and can be bound by either the protein encoded
by this gene or by RNA polymerase II. This protein may act to
disengage RNA polymerase II from TAR during transcriptional
elongation. Alternatively spliced transcripts of this gene may
exist, but their full-length natures have not been determined.
[provided by RefSeq, Jul 2008].
##Evidence-Data-START##
Transcript exon combination :: U38847.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-485 U38847.1 1-485
486-486 AL136124.10 60276-60276 c
487-3515 U38847.1 487-3515
3516-3516 AL136124.10 2399-2399 c
3517-3737 U38847.1 3517-3737
3738-3738 AL355472.19 82785-82785 c
3739-4256 U38847.1 3739-4256
4257-4275 AL355472.19 66092-66110 c
4276-5098 U38847.1 4276-5098
5099-5130 AL355472.19 63599-63630 c
FEATURES Location/Qualifiers
source 1..5130
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q42.3"
gene 1..5130
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/note="TAR (HIV-1) RNA binding protein 1"
/db_xref="GeneID:6894"
/db_xref="HGNC:11568"
/db_xref="MIM:605052"
CDS 1..4866
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/note="TAR (HIV) RNA-binding protein 1; TAR (HIV) RNA
binding protein 1; TAR RNA loop binding protein; TAR
RNA-binding protein 1; TAR RNA-binding protein of 185 kDa;
tRNA methyltransferase 3 homolog"
/codon_start=1
/product="probable methyltransferase TARBP1"
/protein_id="NP_005637.3"
/db_xref="GI:110825988"
/db_xref="CCDS:CCDS1601.1"
/db_xref="GeneID:6894"
/db_xref="HGNC:11568"
/db_xref="MIM:605052"
/translation="
MEWVLAEALLSQSRDPRALLGALCQGEASAERVETLRFLLQRLEDEEARGSGGAGALPEAAREVAAGYLVPLLRSLRGRPAGGPDPSLQPRHRRRVLRAAGAALRSCVRLAGRPQLAAALAEEALRDLLAGWRAPGAEAAVEVLAAVGPCLRPREDGPLLERVAGTAVALALGGGGDGDEAGPAEDAAALVAGRLLPVLVQCGGAALRAVWGGLAAPGASLGSGRVEEKLLVLSALAEKLLPEPGGDRARGAREAGPDARRCWRFWRTVQAGLGQADALTRKRARYLLQRAVEVSAELGADCTCGPQEGNGPSLFWWSERKKDELLKFWENYILIMETLEGNQIHVIKPVLPKLNNLFEYAVSEENGCWLFHPSWHMCIYKRMFESENKILSKEGVIHFLELYETKILPFSPEFSEFIIGPLMDALSESSLYSRSPGQPIGSCSPLGLKLQKFLVTYISLLPEEIKSSFLLKFIRKMTSRHWCAVPILFLSKALANVPRHKALGIDGLLALRDVIHCTMITHQILLRGAAQCYLLQTAMNLLDVEKVSLSDVSTFLMSLRQEESLGRGTSLWTELCDWLRVNESYFKPSPTCSSIGLHKTSLNAYVKSIVQEYVKSSAWETGENCFMPDWFEAKLVSLMVLLAVDVEGMKTQYSGKQRTENVLRIFLDPLLDVLMKFSTNAYMPLLKTDRCLQLLLKLLNTCRLKGSSAQDDEVSTVLQNFFMSTTESISEFILRRLTMNELNSVSDLDRCHLYLMVLTELINLHLKVGWKRGNPIWRVISLLKNASIQHLQEMDSGQEPTVGSQIQRVVSMAALAMVCEAIDQKPELQLDSLHAGPLESFLSSLQLNQTLQKPHAEEQSSYAHPLECSSVLEESSSSQGWGKIVAQYIHDQWVCLSFLLKKYHTLIPTTGSEILEPFLPAVQMPIRTLQSALEALTVLSSDQVLPVFHCLKVLVPKLLTSSESLCIESFDMAWKIISSLSNTQLIFWANLKAFVQFVFDNKVLTIAAKIKGQAYFKIKEIMYKIIEMSAIKTGVFNTLISYCCQSWIVSASNVSQGSLSSAKNYSELILEACIFGTVFRRDQRLVQDVQTFIENLGHDCAANIVMENTKREDHYVRICAVKFLCLLDGSNMSHKLFIEDLAIKLLDKDELVSKSKKRYYVNSLQHRVKNRVWQTLLVLFPRLDQNFLNGIIDRIFQAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEENLKTSICTFLAVLSHLDIITQNIPEKKLILKQALIVVLQWCFNHNFSVRLYALVALKKLWTVCKVLSVEEFDALTPVIESSLHQVESMHGAGNAKKNWQRIQEHFFFATFHPLKDYCLETIFYILPRLSGLIEDEWITIDKFTRFTDVPLAAGFQWYLSQTQLSKLKPGDWSQQDIGTNLVEADNQAEWTDVQKKIIPWNSRVSDLDLELLFQDRAARLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLSHGDTKP
"
misc_feature 4324..4326
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q13395.1); phosphorylation site"
misc_feature 4387..4818
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/note="SpoU rRNA Methylase family; Region: SpoU_methylase;
pfam00588"
/db_xref="CDD:201328"
exon 1..931
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 932..1029
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1030..1099
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 1035
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="c"
/replace="t"
/db_xref="dbSNP:3754307"
exon 1100..1248
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1249..1301
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1302..1399
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1400..1535
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1536..1632
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1633..1722
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1723..1861
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 1862..1961
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 1956
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="g"
/db_xref="dbSNP:2102596"
exon 1962..2134
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 2135..2232
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 2233..2394
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 2358
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="g"
/db_xref="dbSNP:3754311"
exon 2395..2609
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 2610..2871
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 2872..3060
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 3061..3251
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 3113
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="c"
/replace="t"
/db_xref="dbSNP:3820602"
exon 3252..3323
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 3324..3444
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 3445..3555
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 3516
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="c"
/replace="g"
/db_xref="dbSNP:1056488"
exon 3556..3705
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 3706..3792
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 3738
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="g"
/db_xref="dbSNP:1141264"
exon 3793..3989
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 3990..4071
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 4072..4243
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 4075
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="g"
/db_xref="dbSNP:3738616"
exon 4244..4435
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 4257
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="c"
/replace="t"
/db_xref="dbSNP:2175593"
variation 4275
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="g"
/db_xref="dbSNP:2175594"
variation 4287
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="c"
/replace="t"
/db_xref="dbSNP:1134756"
variation 4308
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="g"
/db_xref="dbSNP:1802871"
variation 4381
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="g"
/db_xref="dbSNP:2275654"
exon 4436..4560
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 4561..4697
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
exon 4698..5130
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/inference="alignment:Splign:1.39.8"
variation 4807
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="c"
/replace="t"
/db_xref="dbSNP:12673"
STS 4851..5010
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/standard_name="SHGC-76546"
/db_xref="UniSTS:52595"
variation 4909
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/replace="a"
/replace="t"
/db_xref="dbSNP:6870"
STS 4917..5025
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/standard_name="A006I23"
/db_xref="UniSTS:62608"
STS 4917..5025
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/standard_name="G20847"
/db_xref="UniSTS:62607"
STS 4924..5024
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/standard_name="A009X31"
/db_xref="UniSTS:15874"
STS 4924..5024
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/standard_name="G32953"
/db_xref="UniSTS:117531"
STS 4967..5105
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
/standard_name="SGC31782"
/db_xref="UniSTS:83310"
polyA_signal 5041..5046
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
polyA_site 5065
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
polyA_signal 5076..5081
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
polyA_site 5095
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
polyA_signal 5102..5107
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
polyA_site 5130
/gene="TARBP1"
/gene_synonym="TRM3; TRP-185; TRP185"
ORIGIN
atggagtgggtgctcgcggaagcgctgctctcgcagagccgggacccccgggccctgcttggggcgctgtgccaaggggaggcatccgcggagcgcgtggagacgctgcgcttccttctgcagcggctcgaggacgaggaggcgcgcggcagcgggggcgcaggcgcgctcccggaggcggcgcgcgaggtggctgcagggtacctcgtgccactgctgcggagcctgcgcggacgccccgcgggcggcccggaccccagtctgcagcctcgccaccgccggcgcgtgctgagggcggcgggcgcggccctgcgctcgtgcgtccgcctggccgggcgtccgcagctggcggccgcgctggctgaggaggcgctgcgcgatctgctcgccgggtggcgcgcgcctggcgccgaggctgccgtggaagtgctagcagccgtcgggccatgtttgcggccccgcgaggacgggccgctactggagcgcgtggcggggaccgccgtcgccctggcgctgggcgggggcggggacggggatgaggccgggcctgccgaggacgcggcggcgctggtggccgggcgactgctgccagtgctggtccaatgtggcggggcggcgctgcgggccgtgtggggcgggctggccgcgcctggggcgtccctggggtccggccgcgtagaggagaagctgctggtcctgagcgccctggccgagaagctgttgcccgagcccggcggcgaccgcgcccgcggcgcgcgcgaggcgggcccggacgcccggcgctgctggcgcttctggaggacggtgcaggcggggctgggccaggcggacgccctgacgcgcaagcgagcgcgctacctgctgcagagggcggtggaggtgtcggcggagctgggggccgactgcacctgcgggccccaggaaggaaacggcccaagtctgttttggtggtctgagaggaaaaaagatgagcttctaaagttttgggaaaattatattttaattatggagactttagaaggaaatcagatacatgttataaagccagttttaccaaagctaaacaatctgtttgaatatgcggtgtcagaggaaaatggatgttggctctttcacccatcctggcatatgtgtatttataaaagaatgtttgaaagtgaaaacaaaatcctgtccaaagaaggtgttatccattttttggagctgtatgaaacaaagattcttccattttcaccagaattttctgagtttattattggaccattaatggatgcgctttcagagagctctctgtatagcaggtccccaggccagccaataggaagctgttctccattgggactgaaattacagaagtttttagtcacttatatttctcttcttccagaagaaataaagagtagcttcctattgaagtttattcggaagatgacaagtaggcattggtgtgctgttcccattttgtttctatctaaggctttggcaaatgtcccaagacataaggccctgggtatagatgggcttcttgctctcagggatgttattcattgcactatgatcacacatcagattctcctgagaggggcagcccaatgctaccttcttcaaacagctatgaatttgctagatgtggagaaagtgtcactttctgatgtctcaacttttctcatgtctctgagacaagaggaatccttaggacgaggaacttcattgtggacagagctgtgtgactggctacgtgttaatgaaagctattttaagccatcccctacgtgtagctccattggacttcacaagacatctttaaatgcttatgtaaagagcattgttcaagagtatgttaagtcatctgcttgggaaacaggagaaaactgctttatgcctgattggtttgaagccaagcttgtttctctgatggtcttgctggctgtggatgtggaaggaatgaagactcagtatagcggaaagcagagaacagagaatgtattgcggatattcttagaccctcttctggatgtgcttatgaagtttagtaccaatgcctacatgcccttgctgaagactgacagatgcctccagctgctgttgaagctgttgaacacatgcaggttgaaaggttccagtgcccaagatgatgaggtgtctactgttcttcagaactttttcatgtctactacagagagcatttctgaatttattctcagaagacttactatgaatgagctaaatagtgtttcagatctggatcgttgccatttatacctgatggtgttaactgagcttataaatctgcatttgaaggttgggtggaaaaggggtaaccctatctggagagttatttctcttttgaaaaatgcatccattcagcatcttcaagagatggacagtggacaggagccaacagttggaagtcagattcagagagtagtgagcatggctgccttggccatggtgtgtgaggccatagaccagaagcctgagctgcagctggactctctccatgctgggcccctggaaagcttcctttcctctcttcagctcaatcagacgctgcagaagccccacgcagaggagcagagcagttatgctcaccccttggagtgcagcagtgttttggaagaatcgtcatcttcccaaggatggggaaaaatagttgcacaatatattcatgatcaatgggtgtgcctctctttcctgttgaaaaaatatcacacccttataccaaccacagggagtgaaattctggaaccgtttctacctgccgttcagatgccaataaggactttgcagtctgcactagaagccctcacagttctttcttctgatcaagttttaccagtgttccattgcttgaaagtgttggttcccaagcttctgacttcctctgaatcactctgcatagagtcttttgacatggcgtggaaaattatatcttctttaagcaacactcagctgatattctgggctaatttaaaagcttttgttcagtttgtttttgataacaaagttcttaccattgctgccaaaatcaagggccaggcatatttcaaaataaaagagattatgtacaagataattgaaatgtctgctataaagactggagtcttcaatacactgataagttactgctgtcagtcttggatagtgtctgcttcaaatgtgtcccaaggatctttatcaagtgctaaaaattatagcgaacttatccttgaggcttgtatatttggaactgtgtttaggcgtgatcaaagacttgttcaggatgtacagaccttcatagaaaaccttggacatgactgtgcggcaaatattgttatggaaaatactaagagagaagaccattatgtgagaatttgtgctgtcaaattcctgtgtttattagatggctccaatatgtcccacaagttgtttattgaggatcttgcaatcaagctattagataaagatgaattagtgtccaagtccaaaaaacgctactatgtgaattctctacagcacagagtgaaaaaccgagtgtggcagactctgctggtacttttccctagacttgaccagaatttcttgaatggaattattgacaggattttccaggctggtttcaccaacaatcaagcatccataaaatattttatagaatggattattatattgattcttcataaattccctcaatttcttccaaagttctgggattgtttttcttatggtgaagaaaatcttaaaacaagcatttgtacgtttttagcagttttatcacatttagacattattactcaaaatattccagaaaagaaactaattctgaagcaagcccttatagttgtgctgcagtggtgtttcaatcacaattttagtgttcgactgtatgctttagttgctcttaagaaactctggactgtgtgtaaagtgttaagtgttgaagaatttgatgccctgactcctgtgattgaatccagcctccatcaagtggaaagcatgcacggagcagggaatgccaagaagaattggcaacgcattcaggagcatttcttttttgcaacatttcacccactcaaggattattgtctagagaccatattttacatccttccacgcctttcaggccttattgaagatgaatggatcaccattgataaatttaccagattcactgatgttcctttagctgcgggatttcagtggtacctttctcaaactcaacttagtaaactaaaaccaggtgactggtctcagcaagacataggtactaatttggtcgaagcagataaccaagcggagtggaccgacgttcagaagaagattatcccgtggaacagtcgtgtttccgacttagacctggagctcctgtttcaggatcgtgctgccagacttggaaagtcaattagtagactcatcgttgtggcctcgctcatcgacaaaccgaccaatttaggaggactgtgcaggacctgtgaggtatttggggcttcagtgctcgttgttggcagccttcagtgtatcagcgacaaacagtttcagcacctcagtgtctctgcagaacagtggcttcctctagtggaggtaaaaccacctcagctaattgattatctgcagcagaagaaaacagaaggttataccatcattggagtggaacaaactgccaaaagtttagacctaacccaatattgctttcctgagaaatctctgctcttgttgggaaatgaacgtgagggaattccagcaaatctgatccaacagttggacgtttgtgtggaaattcctcaacagggcattatccgctccctgaatgtccatgtgagtggagccctgctgatctgggagtacaccaggcagcagctgctctcgcacggagataccaagccatgatgtgccttccttagtgaactgctgctgctgttcagacttttttaaaaaaaactatttggactaaagaaacagattctgaaatttattgtgataatttgtatttcttttttcttgcaatttaatgccaaaagtttgccatgtgccttaaacatattactatatattttcccctttaataaacactttttgttaaattgtattcttcctttaataaaatattttaagcaattgtggaaataaaacaatggattttttaagagagaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:6894 -> Molecular function: GO:0003723 [RNA binding] evidence: IEA
GeneID:6894 -> Molecular function: GO:0008173 [RNA methyltransferase activity] evidence: IEA
GeneID:6894 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: TAS
GeneID:6894 -> Biological process: GO:0006396 [RNA processing] evidence: IEA
GeneID:6894 -> Cellular component: GO:0005634 [nucleus] evidence: TAS
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