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2025-05-09 20:02:43, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_004185 2063 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens wingless-type MMTV integration site family, member 2B
(WNT2B), transcript variant WNT-2B1, mRNA.
ACCESSION NM_004185
VERSION NM_004185.3 GI:197333757
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2063)
AUTHORS Wang,H., Fan,L., Xia,X., Rao,Y., Ma,Q., Yang,J., Lu,Y., Wang,C.,
Ma,D. and Huang,X.
TITLE Silencing Wnt2B by siRNA interference inhibits metastasis and
enhances chemotherapy sensitivity in ovarian cancer
JOURNAL Int. J. Gynecol. Cancer 22 (5), 755-761 (2012)
PUBMED 22635028
REMARK GeneRIF: High Wnt2B overexpression is associated with ovarian
cancer metastasis and drug resistance.
REFERENCE 2 (bases 1 to 2063)
AUTHORS Zhang,X., Yang,H., Lee,J.J., Kim,E., Lippman,S.M., Khuri,F.R.,
Spitz,M.R., Lotan,R., Hong,W.K. and Wu,X.
TITLE MicroRNA-related genetic variations as predictors for risk of
second primary tumor and/or recurrence in patients with early-stage
head and neck cancer
JOURNAL Carcinogenesis 31 (12), 2118-2123 (2010)
PUBMED 20819778
REMARK GeneRIF: Observational study of gene-disease association and
gene-gene interaction. (HuGE Navigator)
REFERENCE 3 (bases 1 to 2063)
AUTHORS Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B,
Yusuf S, Gerstein HC, Engert JC and Anand S.
CONSRTM DREAM investigators
TITLE Variation at the NFATC2 locus increases the risk of
thiazolidinedione-induced edema in the Diabetes REduction
Assessment with ramipril and rosiglitazone Medication (DREAM) study
JOURNAL Diabetes Care 33 (10), 2250-2253 (2010)
PUBMED 20628086
REMARK GeneRIF: Observational study of gene-disease association,
gene-environment interaction, and pharmacogenomic / toxicogenomic.
(HuGE Navigator)
REFERENCE 4 (bases 1 to 2063)
AUTHORS Fernandez-Rozadilla C, de Castro L, Clofent J, Brea-Fernandez A,
Bessa X, Abuli A, Andreu M, Jover R, Xicola R, Llor X, Castells A,
Castellvi-Bel S, Carracedo A and Ruiz-Ponte C.
CONSRTM Gastrointestinal Oncology Group of the Spanish Gastroenterological
Association
TITLE Single nucleotide polymorphisms in the Wnt and BMP pathways and
colorectal cancer risk in a Spanish cohort
JOURNAL PLoS ONE 5 (9) (2010)
PUBMED 20844743
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
Publication Status: Online-Only
REFERENCE 5 (bases 1 to 2063)
AUTHORS Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt
TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M,
Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ,
Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S,
Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD,
Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE
and Hingorani AD.
CONSRTM ASCOT investigators; NORDIL investigators; BRIGHT Consortium
TITLE Gene-centric association signals for lipids and apolipoproteins
identified via the HumanCVD BeadChip
JOURNAL Am. J. Hum. Genet. 85 (5), 628-642 (2009)
PUBMED 19913121
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 2063)
AUTHORS Katoh,M., Kirikoshi,H., Saitoh,T., Sagara,N. and Koike,J.
TITLE Alternative splicing of the WNT-2B/WNT-13 gene
JOURNAL Biochem. Biophys. Res. Commun. 275 (1), 209-216 (2000)
PUBMED 10944466
REFERENCE 7 (bases 1 to 2063)
AUTHORS Van Den Berg,D.J., Sharma,A.K., Bruno,E. and Hoffman,R.
TITLE Role of members of the Wnt gene family in human hematopoiesis
JOURNAL Blood 92 (9), 3189-3202 (1998)
PUBMED 9787155
REFERENCE 8 (bases 1 to 2063)
AUTHORS Bergstein,I., Eisenberg,L.M., Bhalerao,J., Jenkins,N.A.,
Copeland,N.G., Osborne,M.P., Bowcock,A.M. and Brown,A.M.
TITLE Isolation of two novel WNT genes, WNT14 and WNT15, one of which
(WNT15) is closely linked to WNT3 on human chromosome 17q21
JOURNAL Genomics 46 (3), 450-458 (1997)
PUBMED 9441749
REFERENCE 9 (bases 1 to 2063)
AUTHORS Katoh,M., Hirai,M., Sugimura,T. and Terada,M.
TITLE Cloning, expression and chromosomal localization of Wnt-13, a novel
member of the Wnt gene family
JOURNAL Oncogene 13 (4), 873-876 (1996)
PUBMED 8761309
REFERENCE 10 (bases 1 to 2063)
AUTHORS Smolich,B.D., McMahon,J.A., McMahon,A.P. and Papkoff,J.
TITLE Wnt family proteins are secreted and associated with the cell
surface
JOURNAL Mol. Biol. Cell 4 (12), 1267-1275 (1993)
PUBMED 8167409
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AB045116.1 and BC141825.1.
On Aug 29, 2008 this sequence version replaced gi:13518016.
Summary: This gene encodes a member of the wingless-type MMTV
integration site (WNT) family of highly conserved, secreted
signaling factors. WNT family members function in a variety of
developmental processes including regulation of cell growth and
differentiation and are characterized by a WNT-core domain. This
gene may play a role in human development as well as human
carcinogenesis. This gene produces two alternatively spliced
transcript variants. [provided by RefSeq, Aug 2008].
Transcript Variant: This variant (WNT-2B1) contains different
segments for its 5' UTR and 5' coding region, compared to
transcript variant WNT-2B2. The encoded protein (isoform WNT-2B1)
has a shorter and distinct N-terminus when it is compared to
isoform WNT-2B2.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-1232 AB045116.1 1-1232
1233-2063 BC141825.1 1685-2515
FEATURES Location/Qualifiers
source 1..2063
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p13"
gene 1..2063
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="wingless-type MMTV integration site family, member
2B"
/db_xref="GeneID:7482"
/db_xref="HGNC:12781"
/db_xref="HPRD:03574"
/db_xref="MIM:601968"
exon 1..174
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
misc_feature 58..60
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="upstream in-frame stop codon"
STS 73..1281
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/db_xref="UniSTS:482015"
variation 84
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:371825913"
variation 116
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374777255"
CDS 121..1239
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="isoform WNT-2B1 is encoded by transcript variant
WNT-2B1; XWNT2, Xenopus, homolog of; wingless-type MMTV
integration site family, member 13; protein Wnt-2b"
/codon_start=1
/product="protein Wnt-2b isoform WNT-2B1"
/protein_id="NP_004176.2"
/db_xref="GI:13518017"
/db_xref="CCDS:CCDS846.1"
/db_xref="GeneID:7482"
/db_xref="HGNC:12781"
/db_xref="HPRD:03574"
/db_xref="MIM:601968"
/translation="
MLDGLGVVAISIFGIQLKTEGSLRTAVPGIPTQSAFNKCLQRYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFTAARQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT
"
misc_feature 274..1203
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="wnt family; Region: wnt; pfam00110"
/db_xref="CDD:201009"
misc_feature 283..1203
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="found in Wnt-1; Region: WNT1; smart00097"
/db_xref="CDD:128408"
misc_feature 382..1200
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="Region: WNT-core domain"
misc_feature 910..912
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/note="glycosylation site"
misc_feature 910..912
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/experiment="experimental evidence, no additional details
recorded"
/note="glycosylation site"
variation 139
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:142980721"
variation 156
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="g"
/replace="t"
/db_xref="dbSNP:189656664"
exon 175..245
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
exon 246..466
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 264
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377342580"
variation 268
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370244148"
variation 304
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374175549"
variation 323
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:79888517"
variation 325
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199744667"
variation 326
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368523301"
variation 352
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201662450"
variation 365
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140445206"
variation 431
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145011115"
variation 432
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372534893"
variation 441
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142129756"
variation 442
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140255509"
variation 457
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="t"
/db_xref="dbSNP:184557937"
variation 458
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141257308"
exon 467..744
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 519
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:137855546"
variation 520
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150473635"
variation 522
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202077038"
variation 531
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:116923670"
variation 554
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149608763"
variation 576
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189277982"
variation 587
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373636614"
variation 602
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:35058556"
variation 607
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147459875"
variation 614
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:142716277"
variation 645
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149716293"
variation 666
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200972987"
variation 670
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:351371"
variation 682
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146253356"
variation 709
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:372960279"
variation 731
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="g"
/replace="t"
/db_xref="dbSNP:180824040"
variation 739
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377518381"
exon 745..1009
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 769
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:140289496"
variation 795
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112638528"
STS 799..1135
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/standard_name="Wnt2b"
/db_xref="UniSTS:465418"
variation 821
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375265204"
variation 838
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201153849"
variation 879
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="t"
/db_xref="dbSNP:141070301"
variation 894
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201268308"
variation 918
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368272752"
variation 919
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150246330"
variation 926
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143127439"
STS 945..1086
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/standard_name="Wnt2b"
/db_xref="UniSTS:466087"
variation 949
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199991957"
variation 963
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372397139"
variation 1003
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:138326201"
exon 1010..2018
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/inference="alignment:Splign:1.39.8"
variation 1023
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146027356"
variation 1046
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201658677"
variation 1064
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368029359"
variation 1070
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:192061205"
variation 1080
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371343411"
variation 1100
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201872478"
variation 1112
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:374641766"
variation 1115
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144189370"
variation 1122
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:141296639"
variation 1159
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368700550"
variation 1188
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139266843"
variation 1189
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:111919963"
variation 1196
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="c"
/db_xref="dbSNP:372190907"
variation 1203
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2227860"
variation 1206
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145437043"
variation 1233
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:910697"
variation 1268
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200355523"
variation 1534
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:17030446"
variation 1537
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373531874"
variation 1614
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1569932"
STS 1630..1791
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/standard_name="RH102745"
/db_xref="UniSTS:97079"
variation 1673
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113309659"
variation 1688
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190688758"
variation 1692
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376487188"
variation 1797..1798
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace=""
/replace="at"
/db_xref="dbSNP:139624875"
variation 1858
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143485662"
variation 1879
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2273368"
variation 1920
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181978420"
variation 1925
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184488483"
polyA_signal 1975..1980
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
polyA_site 1993
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
polyA_site 1994
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
variation 2008
/gene="WNT2B"
/gene_synonym="WNT13; XWNT2"
/replace="a"
/replace="t"
/db_xref="dbSNP:146289905"
ORIGIN
aaaccctgaagagcccaagcaatgtggttgtaaaatttgcaaaataagattaaatcttaactgcaatctgttaacactgctgtctcctttcactctttctcctatatcacactttcccacatgttggatggccttggagtggtagccataagcatttttggaattcaactaaaaactgaaggatccttgaggacggcagtacctggcatacctacacagtcagcgttcaacaagtgtttgcaaaggtacattggggcactgggggcacgagtgatctgtgacaatatccctggtttggtgagccggcagcggcagctgtgccagcgttacccagacatcatgcgttcagtgggcgagggtgcccgagaatggatccgagagtgtcagcaccaattccgccaccaccgctggaactgtaccaccctggaccgggaccacaccgtctttggccgtgtcatgctcagaagtagccgagaggcagcttttgtatatgccatctcatcagcaggggtagtccacgctattactcgcgcctgtagccagggtgaactgagtgtgtgcagctgtgacccctacacccgtggccgacaccatgaccagcgtggggactttgactggggtggctgcagtgacaacatccactacggtgtccgttttgccaaggccttcgtggatgccaaggagaagaggcttaaggatgcccgggccctcatgaacttacataataaccgctgtggtcgcacggctgtgcggcggtttctgaagctggagtgtaagtgccatggcgtgagtggttcctgtactctgcgcacctgctggcgtgcactctcagatttccgccgcacaggtgattacctgcggcgacgctatgatggggctgtgcaggtgatggccacccaagatggtgccaacttcaccgcagcccgccaaggctatcgccgtgccacccggactgatcttgtctactttgacaactctccagattactgtgtcttggacaaggctgcaggttccctaggcactgcaggccgtgtctgcagcaagacatcaaaaggaacagacggttgtgaaatcatgtgctgtggccgagggtacgacacaactcgagtcacccgtgttacccagtgtgagtgcaaattccactggtgctgtgctgtacggtgcaaggaatgcagaaatactgtggacgtccatacttgcaaagcccccaagaaggcagagtggctggaccaaacctgaacacacagatacctcactcatccctccaattcaagcctctcaactcaaaagcacaagatccttgcatgcacaccttcctccaccctccaccctgggctgctaccgcttctatttaaggatgtagagagtaatccatagggaccatggtgtcctggctggttccttagccctgggaaggagttgtcaggggatataagaaactgagcaagctccctgatttcccgctctggagatttgaagggagagtagaagagatagggggtctttagagtgaaatgagttgcactaaagtacgtagttgaggctccttttttctttcctttgcaccagcttcccgatacttcttggtgtgcaagaggaagggtacctgtagagagcttctttttgtttctacctggccaaagttagatgggacaaagatgaatggcatgtcccttctctgaagtccgtttgagcagaactacctggtaccccgaaagaaaatcttaggctaccacattctattattgagagcctgagatgttagccatagtggacaaggttccattcacatgctcatatgtttataaactgtgttttgtagaagaaaaagaatcataacaatacaaacacacattcattctctctttttctctctaccattctcaacctgtattggacagcactgcctcttttgcttacttgctgcctgttcaaactgaggtggaatgcagtggttcccatgcttaacaaatcattaaaacaccctagaacactcctaggatagattaatgtagtaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:7482 -> Molecular function: GO:0005109 [frizzled binding] evidence: IBA
GeneID:7482 -> Biological process: GO:0002062 [chondrocyte differentiation] evidence: IEP
GeneID:7482 -> Biological process: GO:0002088 [lens development in camera-type eye] evidence: ISS
GeneID:7482 -> Biological process: GO:0008584 [male gonad development] evidence: IEP
GeneID:7482 -> Biological process: GO:0016055 [Wnt receptor signaling pathway] evidence: IMP
GeneID:7482 -> Biological process: GO:0021871 [forebrain regionalization] evidence: IEP
GeneID:7482 -> Biological process: GO:0030182 [neuron differentiation] evidence: IBA
GeneID:7482 -> Biological process: GO:0030182 [neuron differentiation] evidence: ISS
GeneID:7482 -> Biological process: GO:0045165 [cell fate commitment] evidence: IBA
GeneID:7482 -> Biological process: GO:0060070 [canonical Wnt receptor signaling pathway] evidence: IEA
GeneID:7482 -> Biological process: GO:0060492 [lung induction] evidence: IEA
GeneID:7482 -> Biological process: GO:0060638 [mesenchymal-epithelial cell signaling] evidence: IEA
GeneID:7482 -> Biological process: GO:0061072 [iris morphogenesis] evidence: ISS
GeneID:7482 -> Biological process: GO:0061303 [cornea development in camera-type eye] evidence: ISS
GeneID:7482 -> Biological process: GO:0071425 [hematopoietic stem cell proliferation] evidence: IDA
GeneID:7482 -> Biological process: GO:0090190 [positive regulation of branching involved in ureteric bud morphogenesis] evidence: IEA
GeneID:7482 -> Biological process: GO:0090263 [positive regulation of canonical Wnt receptor signaling pathway] evidence: IDA
GeneID:7482 -> Cellular component: GO:0005576 [extracellular region] evidence: TAS
GeneID:7482 -> Cellular component: GO:0005578 [proteinaceous extracellular matrix] evidence: IEA
GeneID:7482 -> Cellular component: GO:0005615 [extracellular space] evidence: NAS
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DBCLS
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