2025-05-09 19:40:13, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001271282 6192 bp mRNA linear PRI 24-JUN-2013 DEFINITION Homo sapiens dicer 1, ribonuclease type III (DICER1), transcript variant 4, mRNA. ACCESSION NM_001271282 VERSION NM_001271282.1 GI:404312695 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 6192) AUTHORS Redfern,A.D., Colley,S.M., Beveridge,D.J., Ikeda,N., Epis,M.R., Li,X., Foulds,C.E., Stuart,L.M., Barker,A., Russell,V.J., Ramsay,K., Kobelke,S.J., Li,X., Hatchell,E.C., Payne,C., Giles,K.M., Messineo,A., Gatignol,A., Lanz,R.B., O'Malley,B.W. and Leedman,P.J. TITLE RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators JOURNAL Proc. Natl. Acad. Sci. U.S.A. 110 (16), 6536-6541 (2013) PUBMED 23550157 REMARK GeneRIF: RISC proteins PACT, TRBP, and Dicer, together with PKR, are steroid receptor RNA activator-binding nuclear receptor coregulators that are recruited to the promoters of hormone-regulated genes and regulate the expression of downstream target genes. REFERENCE 2 (bases 1 to 6192) AUTHORS Vincenzi,B., Zoccoli,A., Schiavon,G., Iuliani,M., Pantano,F., Dell'aquila,E., Ratta,R., Muda,A.O., Perrone,G., Brunelli,C., Correale,P., Riva,E., Russo,A., Loupakis,F., Falcone,A., Santini,D. and Tonini,G. TITLE Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients JOURNAL Eur. J. Cancer 49 (6), 1501-1508 (2013) PUBMED 23266047 REMARK GeneRIF: Data indicate that tumour sample showed a significantly higher Drosha expression versus normal mucosa, while Dicer levels did not differ. REFERENCE 3 (bases 1 to 6192) AUTHORS Velez Edwards,D.R., Naj,A.C., Monda,K., North,K.E., Neuhouser,M., Magvanjav,O., Kusimo,I., Vitolins,M.Z., Manson,J.E., O'Sullivan,M.J., Rampersaud,E. and Edwards,T.L. TITLE Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study JOURNAL Hum. Genet. 132 (3), 323-336 (2013) PUBMED 23192594 REFERENCE 4 (bases 1 to 6192) AUTHORS Oshlag,J.Z., Devasthanam,A.S. and Tomasi,T.B. TITLE Mild hyperthermia enhances the expression and induces oscillations in the Dicer protein JOURNAL Int J Hyperthermia 29 (1), 51-61 (2013) PUBMED 23311378 REMARK GeneRIF: Heat-induced regulation of Dicer expression occurs primarily post- transcriptionally, and the expression levels of Dicer protein are increased and often oscillate in response to fever-range hyperthermia in multiple mouse and human cells REFERENCE 5 (bases 1 to 6192) AUTHORS Li,X., Tian,X., Zhang,B., Zhang,Y. and Chen,J. TITLE Variation in dicer gene is associated with increased survival in T-cell lymphoma JOURNAL PLoS ONE 7 (12), E51640 (2012) PUBMED 23251602 REMARK GeneRIF: Dicer rs3742330 is associated with T cell lymphoma survival. REFERENCE 6 (bases 1 to 6192) AUTHORS Provost,P., Dishart,D., Doucet,J., Frendewey,D., Samuelsson,B. and Radmark,O. TITLE Ribonuclease activity and RNA binding of recombinant human Dicer JOURNAL EMBO J. 21 (21), 5864-5874 (2002) PUBMED 12411504 REMARK GeneRIF: cloning and expression of the 218 kDa human Dicer, and characterization of its ribonuclease activity and dsRNA-binding properties REFERENCE 7 (bases 1 to 6192) AUTHORS Tabara,H., Yigit,E., Siomi,H. and Mello,C.C. TITLE The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans JOURNAL Cell 109 (7), 861-871 (2002) PUBMED 12110183 REFERENCE 8 (bases 1 to 6192) AUTHORS Suk,K., Kim,S., Kim,Y.H., Oh,S.H., Lee,M.K., Kim,K.W., Kim,H.D. and Seo,Y.S. TITLE Identification of a novel human member of the DEAD box protein family JOURNAL Biochim. Biophys. Acta 1501 (1), 63-69 (2000) PUBMED 10727850 REFERENCE 9 (bases 1 to 6192) AUTHORS Matsuda,S., Ichigotani,Y., Okuda,T., Irimura,T., Nakatsugawa,S. and Hamaguchi,M. TITLE Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase JOURNAL Biochim. Biophys. Acta 1490 (1-2), 163-169 (2000) PUBMED 10786632 REFERENCE 10 (bases 1 to 6192) AUTHORS Provost,P., Samuelsson,B. and Radmark,O. TITLE Interaction of 5-lipoxygenase with cellular proteins JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (5), 1881-1885 (1999) PUBMED 10051563 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ132261.2 and AL390254.6. Summary: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ132261.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-6089 AJ132261.2 9-6097 6090-6090 AL390254.6 9579-9579 6091-6192 AJ132261.2 6099-6200 FEATURES Location/Qualifiers source 1..6192 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="14" /map="14q32.13" gene 1..6192 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="dicer 1, ribonuclease type III" /db_xref="GeneID:23405" /db_xref="HGNC:17098" /db_xref="MIM:606241" exon 1..188 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(21) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:139513971" variation complement(80) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:184480459" variation complement(144) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:192166518" variation complement(172) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:77127618" exon 189..377 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(214) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:370105837" misc_feature 231..233 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="upstream in-frame stop codon" variation complement(231) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:200884347" CDS 234..6002 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /EC_number="3.1.26.-" /note="isoform 1 is encoded by transcript variant 4; K12H4.8-LIKE; helicase-moi; dicer 1, double-stranded RNA-specific endoribonuclease; helicase with RNAse motif; endoribonuclease Dicer; helicase MOI; Dicer1, Dcr-1 homolog" /codon_start=1 /product="endoribonuclease Dicer isoform 1" /protein_id="NP_001258211.1" /db_xref="GI:404312696" /db_xref="CCDS:CCDS9931.1" /db_xref="GeneID:23405" /db_xref="HGNC:17098" /db_xref="MIM:606241" /translation="
MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETDIDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPADFRYPNLDFGWKKSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRTSSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGNQLNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGNANKSTSDGSPVMAVMPGTTDTIQVLKGRMDSEQSPSIGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAPKEEADYEDDFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSSLGSMPFSSDFEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVSCAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS
" misc_feature 405..860 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046" /db_xref="CDD:28927" misc_feature 432..446 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="ATP binding site [chemical binding]; other site" /db_xref="CDD:28927" misc_feature 756..767 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (Q9UPY3.3); Region: DECH box" misc_feature 756..767 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="putative Mg++ binding site [ion binding]; other site" /db_xref="CDD:28927" misc_feature 999..2018 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (Q9UPY3.3); Region: Required for interaction with PRKRA and TARBP2" misc_feature 1470..1472 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (Q9UPY3.3); phosphorylation site" misc_feature 1476..1478 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (Q9UPY3.3); phosphorylation site" misc_feature <1563..1892 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079" /db_xref="CDD:28960" misc_feature order(1578..1589,1677..1682,1788..1796) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="nucleotide binding region [chemical binding]; other site" /db_xref="CDD:28960" misc_feature order(1812..1814,1875..1877,1887..1889) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="ATP-binding site [chemical binding]; other site" /db_xref="CDD:28960" misc_feature 2121..2399 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="Double stranded RNA binding domain; Region: dsRNA_bind; pfam03368" /db_xref="CDD:190615" misc_feature 2889..3257 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:30328" misc_feature order(3078..3080,3117..3119,3135..3137,3147..3149, 3201..3203,3225..3227,3231..3233) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:30328" misc_feature 3279..3281 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (Q9UPY3.3); phosphorylation site" misc_feature 4110..>4331 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="dsRNA-specific ribonuclease [Transcription]; Region: Rnc; COG0571" /db_xref="CDD:30916" misc_feature 4119..>4361 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593" /db_xref="CDD:29697" misc_feature order(4170..4175,4182..4187,4194..4196,4203..4208, 4215..4220,4224..4232,4260..4262) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="dimerization interface [polypeptide binding]; other site" /db_xref="CDD:29697" misc_feature order(4170..4172,4179..4181,4191..4193) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="active site" /db_xref="CDD:29697" misc_feature 5274..5771 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593" /db_xref="CDD:29697" misc_feature order(5337..5342,5349..5354,5361..5363,5370..5375, 5382..5387,5391..5399,5427..5429,5691..5693,5724..5726) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="dimerization interface [polypeptide binding]; other site" /db_xref="CDD:29697" misc_feature order(5337..5339,5346..5348,5358..5360,5661..5663, 5670..5672) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="active site" /db_xref="CDD:29697" misc_feature order(5346..5348,5661..5663,5670..5672) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /note="metal binding site [ion binding]; metal-binding site" /db_xref="CDD:29697" misc_feature 5649..5651 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="non-experimental evidence, no additional details recorded" /note="Important for activity (By similarity); propagated from UniProtKB/Swiss-Prot (Q9UPY3.3); other site" variation complement(253) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:117358479" variation complement(292) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:147660793" variation complement(310) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:201358110" variation complement(316) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:61729796" variation complement(361) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:367797765" exon 378..540 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(445) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:376657431" variation complement(453) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:202181696" variation complement(454) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:200331768" variation complement(479) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:111483821" variation complement(481) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373646414" variation complement(509) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:370551656" exon 541..671 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(575) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373926076" variation complement(599) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:368741914" variation complement(607) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:377669634" variation complement(609) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373734886" variation complement(665) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:370784723" exon 672..806 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(695) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:199737359" variation complement(714) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373532001" variation complement(718) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:142815547" variation complement(766) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:201239474" variation complement(772) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:375454363" variation complement(785) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:148530092" exon 807..967 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(822) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:375689793" variation complement(872) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:370474705" variation complement(929) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:147505764" exon 968..1136 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(972) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:369189695" variation complement(980) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:376070315" variation complement(1004) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:12432511" variation complement(1006) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:188327838" variation complement(1130) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:201842071" exon 1137..1609 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(1153) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:149718671" variation complement(1157) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:142397473" variation complement(1350) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:369145814" variation complement(1357) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:148758903" variation complement(1376) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:372592852" variation complement(1408) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:142635816" variation complement(1466) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:111595160" variation complement(1482) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:150714784" variation complement(1593) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:368535616" variation complement(1595) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:201615540" exon 1610..1742 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(1614) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:141163928" variation complement(1616) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:202029334" variation complement(1699) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:200866760" variation complement(1729) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:4566088" variation 1740 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:137852977" exon 1743..1985 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(1776) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:148218787" variation complement(1816) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:143099538" variation 1863 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:137852979" variation complement(1864) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:143533680" variation complement(1893) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:148532788" variation complement(1902) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:139198222" variation complement(1914) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:147493562" variation complement(1924) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:201298288" variation complement(1925) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:143117334" exon 1986..2140 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(1991) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:368558276" variation complement(2033) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:199995391" variation complement(2058) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:114947750" variation complement(2060) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:150087634" variation complement(2070) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:201553563" variation complement(2072) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:147754242" variation complement(2110) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:375579739" variation complement(2120) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:141651702" exon 2141..2273 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(2168) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:61751177" variation complement(2186) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:199678028" variation complement(2212) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:151272381" variation complement(2252) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:12437122" variation complement(2265) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:377269341" variation complement(2271) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:201883449" exon 2274..2349 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(2281) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:373914672" variation complement(2282) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:368736189" variation complement(2283) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:142300389" variation complement(2332) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:376691754" variation complement(2348) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:140087741" exon 2350..2489 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(2351) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:191755360" variation complement(2408) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:377025998" variation complement(2429) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:146475655" variation complement(2432) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:201668559" exon 2490..2669 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(2594) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:367950170" variation complement(2603) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:112712209" exon 2670..2883 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(2723) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:139444980" variation 2749 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:387906934" variation complement(2769) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:201212908" variation complement(2786) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373715574" variation complement(2790) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:61729795" variation complement(2808) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:144649926" variation complement(2847) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:149242330" exon 2884..3037 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(2893) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:139441077" variation complement(2922) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373729361" variation complement(2950) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:150510758" variation complement(2951) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:370692165" variation complement(2953) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:200408568" variation complement(2985) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:377326167" exon 3038..3220 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation 3063 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:137852978" variation complement(3131) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:375772460" variation complement(3210) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:112390607" exon 3221..3326 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(3230) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:12018992" variation complement(3266) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:8019857" exon 3327..3502 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(3431) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:114964211" variation complement(3446) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:148959399" variation complement(3462) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373412959" variation complement(3467) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:148166836" variation complement(3493) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:180918578" variation complement(3494) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:369869162" variation complement(3497) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:376110719" exon 3503..4283 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(3571) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:143841809" variation complement(3625) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:200651335" variation complement(3660) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:375211466" variation complement(3661) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:139786661" variation complement(3695) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:192822778" variation complement(3698) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:377272036" variation complement(3707) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:368984998" variation complement(3708) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:145693584" variation complement(3724..3725) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="" /replace="t" /db_xref="dbSNP:34141151" variation complement(3728) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:372581591" variation complement(3729) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:368588781" variation complement(3785) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:375535900" variation complement(3786) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:150514959" variation complement(3790) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:201523588" variation complement(3800) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:141288912" variation complement(3818) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:372344332" variation complement(3861) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:200925349" variation complement(3907) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:146584765" variation complement(3908) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:184830847" variation complement(3997) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:199526737" variation complement(4006) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:144095207" variation complement(4024) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:139346443" variation complement(4030) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:368610812" variation complement(4048) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:151197809" variation complement(4053) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:142193936" variation complement(4071) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:148696745" variation complement(4089) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:111495226" variation complement(4092) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:373980178" variation complement(4172) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:191567701" variation complement(4201) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="" /replace="t" /db_xref="dbSNP:35252236" variation complement(4205) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:45562437" variation complement(4220) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373810197" variation complement(4223) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:202227142" variation complement(4247) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:143454689" exon 4284..4439 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(4334) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:370897400" variation complement(4363..4364) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="" /replace="c" /db_xref="dbSNP:34678453" variation complement(4432) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:139536688" exon 4440..5328 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(4440) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:147391538" variation complement(4478) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:373735840" variation complement(4514) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:143985382" variation complement(4529) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:146679273" variation complement(4610) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:138250984" variation complement(4639) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:200890670" variation complement(4656) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:150883389" variation complement(4665) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:372496188" variation complement(4670) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:141556323" variation complement(4708) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:370947079" variation complement(4748) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:141308332" variation complement(4798) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:113234676" variation complement(4808) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:189516161" STS 4872..5362 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /standard_name="Dicer1" /db_xref="UniSTS:498692" variation complement(4880) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:201415999" variation complement(4908) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:377409989" variation complement(4913) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:61729797" variation complement(4931) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:372837448" variation complement(4952) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:141265948" variation complement(4973) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:369465519" variation 4981 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:137852976" variation complement(5006) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:138308365" variation complement(5035) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:181018393" variation complement(5037) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:145669719" variation complement(5038) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:148955573" variation complement(5040) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:201320420" variation complement(5052) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:189119295" variation complement(5053) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:368963384" variation complement(5086) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:377205344" variation complement(5103) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:372967646" variation complement(5122) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:368343829" variation complement(5124) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:145551486" variation complement(5129) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:376515225" variation complement(5134) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:149723645" variation complement(5143) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:140875148" variation complement(5178) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:146715213" variation complement(5219) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:371564184" variation complement(5260) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:375465466" variation complement(5285) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="g" /db_xref="dbSNP:145027662" exon 5329..5597 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(5378) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:139500905" variation complement(5417) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:202004554" variation complement(5423) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:371759757" variation complement(5436) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:188609628" variation complement(5474) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:114861074" variation complement(5489) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:373750374" variation complement(5509) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:144259142" variation complement(5562) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:183879938" variation complement(5570) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:111630745" exon 5598..5760 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(5609) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:17191079" variation complement(5627) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:201134588" variation complement(5704) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="g" /replace="t" /db_xref="dbSNP:377685186" variation complement(5740) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="c" /db_xref="dbSNP:187288681" exon 5761..5836 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(5783) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:377325189" exon 5837..6174 /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /inference="alignment:Splign:1.39.8" variation complement(5876) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:199574382" variation complement(6022) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:200095508" variation complement(6068) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="c" /replace="t" /db_xref="dbSNP:191996364" variation complement(6090) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="t" /db_xref="dbSNP:13078" variation complement(6136) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:140021568" variation complement(6168) /gene="DICER1" /gene_synonym="DCR1; Dicer; HERNA; MNG1" /replace="a" /replace="g" /db_xref="dbSNP:112795042" ORIGIN
gctggtttcatcctaaggctggatcttttcatgggtctgtgtagtgtaattgcagcagcaaatgggactaataatttcatgagtcatctttagagggaaagaaagacaactgcttctcttcaaccatcaaatgaaagtcctaaattttttgctgttggatgagcatgaaccaattcctctggccagggtaagctgtgctagaacaaaaatgcaatgaaagaaacactggatgaatgaaaagccctgctttgcaacccctcagcatggcaggcctgcagctcatgacccctgcttcctcaccaatgggtcctttctttggactgccatggcaacaagaagcaattcatgataacatttatacgccaagaaaatatcaggttgaactgcttgaagcagctctggatcataataccatcgtctgtttaaacactggctcagggaagacatttattgcagtactactcactaaagagctgtcctatcagatcaggggagacttcagcagaaatggaaaaaggacggtgttcttggtcaactctgcaaaccaggttgctcaacaagtgtcagctgtcagaactcattcagatctcaaggttggggaatactcaaacctagaagtaaatgcatcttggacaaaagagagatggaaccaagagtttactaagcaccaggttctcattatgacttgctatgtcgccttgaatgttttgaaaaatggttacttatcactgtcagacattaaccttttggtgtttgatgagtgtcatcttgcaatcctagaccacccctatcgagaaattatgaagctctgtgaaaattgtccatcatgtcctcgcattttgggactaactgcttccattttaaatgggaaatgtgatccagaggaattggaagaaaagattcagaaactagagaaaattcttaagagtaatgctgaaactgcaactgacctggtggtcttagacaggtatacttctcagccatgtgagattgtggtggattgtggaccatttactgacagaagtgggctttatgaaagactgctgatggaattagaagaagcacttaattttatcaatgattgtaatatatctgtacattcaaaagaaagagattctactttaatttcgaaacagatactatcagactgtcgtgccgtattggtagttctgggaccctggtgtgcagataaagtagctggaatgatggtaagagaactacagaaatacatcaaacatgagcaagaggagctgcacaggaaatttttattgtttacagacactttcctaaggaaaatacatgcactatgtgaagagcacttctcacctgcctcacttgacctgaaatttgtaactcctaaagtaatcaaactgctcgaaatcttacgcaaatataaaccatatgagcgacagcagtttgaaagcgttgagtggtataataatagaaatcaggataattatgtgtcatggagtgattctgaggatgatgatgaggatgaagaaattgaagaaaaagagaagccagagacaaattttccttctccttttaccaacattttgtgcggaattatttttgtggaaagaagatacacagcagttgtcttaaacagattgataaaggaagctggcaaacaagatccagagctggcttatatcagtagcaatttcataactggacatggcattgggaagaatcagcctcgcaacaaacagatggaagcagaattcagaaaacaggaagaggtacttaggaaatttcgagcacatgagaccaacctgcttattgcaacaagtattgtagaagagggtgttgatataccaaaatgcaacttggtggttcgttttgatttgcccacagaatatcgatcctatgttcaatctaaaggaagagcaagggcacccatctctaattatataatgttagcggatacagacaaaataaaaagttttgaagaagaccttaaaacctacaaagctattgaaaagatcttgagaaacaagtgttccaagtcggttgatactggtgagactgacattgatcctgtcatggatgatgatgacgttttcccaccatatgtgttgaggcctgacgatggtggtccacgagtcacaatcaacacggccattggacacatcaatagatactgtgctagattaccaagtgatccgtttactcatctagctcctaaatgcagaacccgagagttgcctgatggtacattttattcaactctttatctgccaattaactcacctcttcgagcctccattgttggtccaccaatgagctgtgtacgattggctgaaagagttgtagctctcatttgctgtgagaaactgcacaaaattggcgaactggatgaccatttgatgccagttgggaaagagactgttaaatatgaagaggagcttgatttgcatgatgaagaagagaccagtgttccaggaagaccaggttccacgaaacgaaggcagtgctacccaaaagcaattccagagtgtttgagggatagttatcccagacctgatcagccctgttacctgtatgtgataggaatggttttaactacacctttacctgatgaactcaactttagaaggcggaagctctatcctcctgaagataccacaagatgctttggaatactgacggccaaacccatacctcagattccacactttcctgtgtacacacgctctggagaggttaccatatccattgagttgaagaagtctggtttcatgttgtctctacaaatgcttgagttgattacaagacttcaccagtatatattctcacatattcttcggcttgaaaaacctgcactagaatttaaacctacagacgctgattcagcatactgtgttctacctcttaatgttgttaatgactccagcactttggatattgactttaaattcatggaagatattgagaagtctgaagctcgcataggcattcccagtacaaagtatacaaaagaaacaccctttgtttttaaattagaagattaccaagatgccgttatcattccaagatatcgcaattttgatcagcctcatcgattttatgtagctgatgtgtacactgatcttaccccactcagtaaatttccttcccctgagtatgaaacttttgcagaatattataaaacaaagtacaaccttgacctaaccaatctcaaccagccactgctggatgtggaccacacatcttcaagacttaatcttttgacacctcgacatttgaatcagaaggggaaagcgcttcctttaagcagtgctgagaagaggaaagccaaatgggaaagtctgcagaataaacagatactggttccagaactctgtgctatacatccaattccagcatcactgtggagaaaagctgtttgtctccccagcatactttatcgccttcactgccttttgactgcagaggagctaagagcccagactgccagcgatgctggcgtgggagtcagatcacttcctgcggattttagataccctaacttagacttcgggtggaaaaaatctattgacagcaaatctttcatctcaatttctaactcctcttcagctgaaaatgataattactgtaagcacagcacaattgtccctgaaaatgctgcacatcaaggtgctaatagaacctcctctctagaaaatcatgaccaaatgtctgtgaactgcagaacgttgctcagcgagtcccctggtaagctccacgttgaagtttcagcagatcttacagcaattaatggtctttcttacaatcaaaatctcgccaatggcagttatgatttagctaacagagacttttgccaaggaaatcagctaaattactacaagcaggaaatacccgtgcaaccaactacctcatattccattcagaatttatacagttacgagaaccagccccagcccagcgatgaatgtactctcctgagtaataaataccttgatggaaatgctaacaaatctacctcagatggaagtcctgtgatggccgtaatgcctggtacgacagacactattcaagtgctcaagggcaggatggattctgagcagagcccttctattgggtactcctcaaggactcttggccccaatcctggacttattcttcaggctttgactctgtcaaacgctagtgatggatttaacctggagcggcttgaaatgcttggcgactcctttttaaagcatgccatcaccacatatctattttgcacttaccctgatgcgcatgagggccgcctttcatatatgagaagcaaaaaggtcagcaactgtaatctgtatcgccttggaaaaaagaagggactacccagccgcatggtggtgtcaatatttgatccccctgtgaattggcttcctcctggttatgtagtaaatcaagacaaaagcaacacagataaatgggaaaaagatgaaatgacaaaagactgcatgctggcgaatggcaaactggatgaggattacgaggaggaggatgaggaggaggagagcctgatgtggagggctccgaaggaagaggctgactatgaagatgatttcctggagtatgatcaggaacatatcagatttatagataatatgttaatggggtcaggagcttttgtaaagaaaatctctctttctcctttttcaaccactgattctgcatatgaatggaaaatgcccaaaaaatcctccttaggtagtatgccattttcatcagattttgaggattttgactacagctcttgggatgcaatgtgctatctggatcctagcaaagctgttgaagaagatgactttgtggtggggttctggaatccatcagaagaaaactgtggtgttgacacgggaaagcagtccatttcttacgacttgcacactgagcagtgtattgctgacaaaagcatagcggactgtgtggaagccctgctgggctgctatttaaccagctgtggggagagggctgctcagcttttcctctgttcactggggctgaaggtgctcccggtaattaaaaggactgatcgggaaaaggccctgtgccctactcgggagaatttcaacagccaacaaaagaacctttcagtgagctgtgctgctgcttctgtggccagttcacgctcttctgtattgaaagactcggaatatggttgtttgaagattccaccaagatgtatgtttgatcatccagatgcagataaaacactgaatcaccttatatcggggtttgaaaattttgaaaagaaaatcaactacagattcaagaataaggcttaccttctccaggcttttacacatgcctcctaccactacaatactatcactgattgttaccagcgcttagaattcctgggagatgcgattttggactacctcataaccaagcacctttatgaagacccgcggcagcactccccgggggtcctgacagacctgcggtctgccctggtcaacaacaccatctttgcatcgctggctgtaaagtacgactaccacaagtacttcaaagctgtctctcctgagctcttccatgtcattgatgactttgtgcagtttcagcttgagaagaatgaaatgcaaggaatggattctgagcttaggagatctgaggaggatgaagagaaagaagaggatattgaagttccaaaggccatgggggatatttttgagtcgcttgctggtgccatttacatggatagtgggatgtcactggagacagtctggcaggtgtactatcccatgatgcggccactaatagaaaagttttctgcaaatgtaccccgttcccctgtgcgagaattgcttgaaatggaaccagaaactgccaaatttagcccggctgagagaacttacgacgggaaggtcagagtcactgtggaagtagtaggaaaggggaaatttaaaggtgttggtcgaagttacaggattgccaaatctgcagcagcaagaagagccctccgaagcctcaaagctaatcaacctcaggttcccaatagctgaaaccgctttttaaaattcaaaacaagaaacaaaacaaaaaaaattaaggggaaaattatttaaatcggaaaggaagacttaaagttgttagtgagtggaatgaattgaaggcagaatttaaagtttggttgataacaggatagataacagaataaaacatttaacatatgtaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:23405 -> Molecular function: GO:0003725 [double-stranded RNA binding] evidence: IDA GeneID:23405 -> Molecular function: GO:0004525 [ribonuclease III activity] evidence: IDA GeneID:23405 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:23405 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA GeneID:23405 -> Molecular function: GO:0008026 [ATP-dependent helicase activity] evidence: IEA GeneID:23405 -> Molecular function: GO:0035198 [miRNA binding] evidence: IEA GeneID:23405 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA GeneID:23405 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: ISS GeneID:23405 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA GeneID:23405 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA GeneID:23405 -> Biological process: GO:0009791 [post-embryonic development] evidence: IEA GeneID:23405 -> Biological process: GO:0010070 [zygote asymmetric cell division] evidence: IEA GeneID:23405 -> Biological process: GO:0010467 [gene expression] evidence: TAS GeneID:23405 -> Biological process: GO:0010626 [negative regulation of Schwann cell proliferation] evidence: ISS GeneID:23405 -> Biological process: GO:0014040 [positive regulation of Schwann cell differentiation] evidence: ISS GeneID:23405 -> Biological process: GO:0019827 [stem cell maintenance] evidence: IEA GeneID:23405 -> Biological process: GO:0021522 [spinal cord motor neuron differentiation] evidence: IEA GeneID:23405 -> Biological process: GO:0021675 [nerve development] evidence: ISS GeneID:23405 -> Biological process: GO:0021889 [olfactory bulb interneuron differentiation] evidence: IEA GeneID:23405 -> Biological process: GO:0021987 [cerebral cortex development] evidence: IEA GeneID:23405 -> Biological process: GO:0030324 [lung development] evidence: IEA GeneID:23405 -> Biological process: GO:0030422 [production of siRNA involved in RNA interference] evidence: IDA GeneID:23405 -> Biological process: GO:0030423 [targeting of mRNA for destruction involved in RNA interference] evidence: IMP GeneID:23405 -> Biological process: GO:0031054 [pre-miRNA processing] evidence: IDA GeneID:23405 -> Biological process: GO:0031069 [hair follicle morphogenesis] evidence: IEA GeneID:23405 -> Biological process: GO:0031643 [positive regulation of myelination] evidence: ISS GeneID:23405 -> Biological process: GO:0032290 [peripheral nervous system myelin formation] evidence: ISS GeneID:23405 -> Biological process: GO:0035116 [embryonic hindlimb morphogenesis] evidence: IEA GeneID:23405 -> Biological process: GO:0035196 [production of miRNAs involved in gene silencing by miRNA] evidence: ISS GeneID:23405 -> Biological process: GO:0035264 [multicellular organism growth] evidence: IEA GeneID:23405 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: IEA GeneID:23405 -> Biological process: GO:0045069 [regulation of viral genome replication] evidence: IEA GeneID:23405 -> Biological process: GO:0045664 [regulation of neuron differentiation] evidence: IEA GeneID:23405 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA GeneID:23405 -> Biological process: GO:0048536 [spleen development] evidence: IEA GeneID:23405 -> Biological process: GO:0048713 [regulation of oligodendrocyte differentiation] evidence: IEA GeneID:23405 -> Biological process: GO:0048754 [branching morphogenesis of an epithelial tube] evidence: IEA GeneID:23405 -> Biological process: GO:0048812 [neuron projection morphogenesis] evidence: ISS GeneID:23405 -> Biological process: GO:0051225 [spindle assembly] evidence: IEA GeneID:23405 -> Biological process: GO:0051607 [defense response to virus] evidence: IEA GeneID:23405 -> Biological process: GO:0051726 [regulation of cell cycle] evidence: IEA GeneID:23405 -> Biological process: GO:0055013 [cardiac muscle cell development] evidence: IEA GeneID:23405 -> Biological process: GO:0060119 [inner ear receptor cell development] evidence: IEA GeneID:23405 -> Biological process: GO:0060576 [intestinal epithelial cell development] evidence: IEA GeneID:23405 -> Biological process: GO:0070173 [regulation of enamel mineralization] evidence: IEA GeneID:23405 -> Biological process: GO:0071335 [hair follicle cell proliferation] evidence: IEA GeneID:23405 -> Biological process: GO:2000630 [positive regulation of miRNA metabolic process] evidence: IEA GeneID:23405 -> Cellular component: GO:0005829 [cytosol] evidence: TAS GeneID:23405 -> Cellular component: GO:0016442 [RNA-induced silencing complex] evidence: IDA ANNOTATIONS from NCBI Entrez Gene (20130726): NP_001258211 -> EC 3.1.26.-
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