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2025-05-09 20:07:04, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001145851 3881 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens prominin 1 (PROM1), transcript variant 5, mRNA.
ACCESSION NM_001145851
VERSION NM_001145851.1 GI:224994196
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3881)
AUTHORS Zeng,Z., Shaffer,J.R., Wang,X., Feingold,E., Weeks,D.E., Lee,M.,
Cuenco,K.T., Wendell,S.K., Weyant,R.J., Crout,R., McNeil,D.W. and
Marazita,M.L.
TITLE Genome-wide association studies of pit-and-fissure- and
smooth-surface caries in permanent dentition
JOURNAL J. Dent. Res. 92 (5), 432-437 (2013)
PUBMED 23470693
REFERENCE 2 (bases 1 to 3881)
AUTHORS Wei,Y., Jiang,Y., Zou,F., Liu,Y., Wang,S., Xu,N., Xu,W., Cui,C.,
Xing,Y., Liu,Y., Cao,B., Liu,C., Wu,G., Ao,H., Zhang,X. and
Jiang,J.
TITLE Activation of PI3K/Akt pathway by CD133-p85 interaction promotes
tumorigenic capacity of glioma stem cells
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 110 (17), 6829-6834 (2013)
PUBMED 23569237
REMARK GeneRIF: Activation of PI3K/Akt pathway by CD133-p85 interaction
promotes tumorigenic capacity of glioma stem cells.
REFERENCE 3 (bases 1 to 3881)
AUTHORS Rappa,G., Mercapide,J., Anzanello,F., Le,T.T., Johlfs,M.G.,
Fiscus,R.R., Wilsch-Brauninger,M., Corbeil,D. and Lorico,A.
TITLE Wnt interaction and extracellular release of prominin-1/CD133 in
human malignant melanoma cells
JOURNAL Exp. Cell Res. 319 (6), 810-819 (2013)
PUBMED 23318676
REMARK GeneRIF: Down-regulation of CD133 in malignant melanoma cells
impaired substrate and inter-cellular adhesion, cell motility and
invasion. Prominin-1 also mediates Wnt activation.
REFERENCE 4 (bases 1 to 3881)
AUTHORS Koyama-Nasu,R., Takahashi,R., Yanagida,S., Nasu-Nishimura,Y.,
Oyama,M., Kozuka-Hata,H., Haruta,R., Manabe,E., Hoshino-Okubo,A.,
Omi,H., Yanaihara,N., Okamoto,A., Tanaka,T. and Akiyama,T.
TITLE The cancer stem cell marker CD133 interacts with plakoglobin and
controls desmoglein-2 protein levels
JOURNAL PLoS ONE 8 (1), E53710 (2013)
PUBMED 23326490
REMARK GeneRIF: CD133 interacts with plakoglobin and knockdown of CD133 by
RNA interference (RNAi) results in the downregulation of
desmoglein-2.
REFERENCE 5 (bases 1 to 3881)
AUTHORS Canis,M., Lechner,A., Mack,B., Zengel,P., Laubender,R.P.,
Koehler,U., Heissmeyer,V. and Gires,O.
TITLE CD133 is a predictor of poor survival in head and neck squamous
cell carcinomas
JOURNAL Cancer Biomark 12 (2), 97-105 (2012)
PUBMED 23396254
REMARK GeneRIF: A gradual and inversely proportional correlation between
CD133 expression in head and neck tumours and decreased overall
survival was observed, along with a positive correlation with the
presence of lymph node metastases.
REFERENCE 6 (bases 1 to 3881)
AUTHORS Maw,M.A., Corbeil,D., Koch,J., Hellwig,A., Wilson-Wheeler,J.C.,
Bridges,R.J., Kumaramanickavel,G., John,S., Nancarrow,D., Roper,K.,
Weigmann,A., Huttner,W.B. and Denton,M.J.
TITLE A frameshift mutation in prominin (mouse)-like 1 causes human
retinal degeneration
JOURNAL Hum. Mol. Genet. 9 (1), 27-34 (2000)
PUBMED 10587575
REFERENCE 7 (bases 1 to 3881)
AUTHORS Kniazeva,M., Chiang,M.F., Morgan,B., Anduze,A.L., Zack,D.J., Han,M.
and Zhang,K.
TITLE A new locus for autosomal dominant stargardt-like disease maps to
chromosome 4
JOURNAL Am. J. Hum. Genet. 64 (5), 1394-1399 (1999)
PUBMED 10205271
REFERENCE 8 (bases 1 to 3881)
AUTHORS Horn,P.A., Tesch,H., Staib,P., Kube,D., Diehl,V. and Voliotis,D.
TITLE Expression of AC133, a novel hematopoietic precursor antigen, on
acute myeloid leukemia cells
JOURNAL Blood 93 (4), 1435-1437 (1999)
PUBMED 10075457
REFERENCE 9 (bases 1 to 3881)
AUTHORS Miraglia,S., Godfrey,W., Yin,A.H., Atkins,K., Warnke,R.,
Holden,J.T., Bray,R.A., Waller,E.K. and Buck,D.W.
TITLE A novel five-transmembrane hematopoietic stem cell antigen:
isolation, characterization, and molecular cloning
JOURNAL Blood 90 (12), 5013-5021 (1997)
PUBMED 9389721
REFERENCE 10 (bases 1 to 3881)
AUTHORS Yin,A.H., Miraglia,S., Zanjani,E.D., Almeida-Porada,G., Ogawa,M.,
Leary,A.G., Olweus,J., Kearney,J. and Buck,D.W.
TITLE AC133, a novel marker for human hematopoietic stem and progenitor
cells
JOURNAL Blood 90 (12), 5002-5012 (1997)
PUBMED 9389720
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC012089.1, AY449691.1,
DB326234.1 and AA622198.1.
Summary: This gene encodes a pentaspan transmembrane glycoprotein.
The protein localizes to membrane protrusions and is often
expressed on adult stem cells, where it is thought to function in
maintaining stem cell properties by suppressing differentiation.
Mutations in this gene have been shown to result in retinitis
pigmentosa and Stargardt disease. Expression of this gene is also
associated with several types of cancer. This gene is expressed
from at least five alternative promoters that are expressed in a
tissue-dependent manner. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq, Mar 2009].
Transcript Variant: This variant (5) lacks an alternate in-frame
exon in the 5' coding region and a second in-frame exon in the 3'
coding region, compared to variant 1. The resulting isoform (5),
also known as s10, lacks an internal segment near the N-terminus
and a second internal segment near the C-terminus, compared to
isoform 1. The full structure of the 5' UTR for this variant has
not been determined.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
CDS exon combination :: AY449691.1 [ECO:0000331]
RNAseq introns :: mixed/partial sample support ERS025082,
ERS025083 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-212 BC012089.1 24-235
213-2714 AY449691.1 1-2502
2715-3335 BC012089.1 2807-3427
3336-3742 DB326234.1 138-544 c
3743-3878 DB326234.1 1-136 c
3879-3881 AA622198.1 6-8 c
FEATURES Location/Qualifiers
source 1..3881
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4p15.32"
gene 1..3881
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/note="prominin 1"
/db_xref="GeneID:8842"
/db_xref="HGNC:9454"
/db_xref="MIM:604365"
exon 1..432
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
misc_feature 162..164
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/note="upstream in-frame stop codon"
CDS 213..2714
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/note="isoform 5 precursor is encoded by transcript
variant 5; hProminin; hematopoietic stem cell antigen;
antigen AC133; prominin-like protein 1"
/codon_start=1
/product="prominin-1 isoform 5 precursor"
/protein_id="NP_001139323.1"
/db_xref="GI:224994197"
/db_xref="GeneID:8842"
/db_xref="HGNC:9454"
/db_xref="MIM:604365"
/translation="
MALVLGSLLLLGLCGNSFSGGQPSSTDAPKAWNYELPATNYETQDSHKAGPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSELESLKVNLNIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYRRMDSEDVYDDVETIPMKNPSQH
"
sig_peptide 213..269
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
misc_feature 276..2675
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/note="Prominin; Region: Prominin; pfam05478"
/db_xref="CDD:203254"
exon 433..488
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 489..694
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 695..815
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 816..879
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 880..969
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 970..1187
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
variation 971
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/replace="a"
/replace="g"
/db_xref="dbSNP:2286455"
exon 1188..1262
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 1263..1326
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 1327..1486
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 1487..1639
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 1640..1763
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 1764..1867
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 1868..1952
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 1953..2096
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2097..2168
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2169..2261
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2262..2315
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2316..2396
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2397..2465
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2466..2558
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2559..2674
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2675..2698
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2699..2738
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
exon 2739..3881
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/inference="alignment:Splign:1.39.8"
variation 2952
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/replace="c"
/replace="t"
/db_xref="dbSNP:2240687"
variation 3381
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/replace="a"
/replace="c"
/db_xref="dbSNP:2240688"
STS 3602..3849
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/standard_name="WI-22012"
/db_xref="UniSTS:18249"
STS 3670..3814
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/standard_name="RH121881"
/db_xref="UniSTS:137735"
variation 3833
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
/replace="c"
/replace="t"
/db_xref="dbSNP:1053767"
polyA_signal 3857..3862
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
polyA_site 3881
/gene="PROM1"
/gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
PROML1; RP41; STGD4"
ORIGIN
ggatggtgccttgagtgaatgacccccttggagaacattcttccgcatccctcgcctcaagccagcctcagacagaaaactgaagattcagcagatccagtgcttcctgctcctcttctgcccaggaacacgcttgccttccccaaggcttccagaagctctgaggcaggaggcaccaagttctacctcatgtttggaggatcttgctagctatggccctcgtactcggctccctgttgctgctggggctgtgcgggaactccttttcaggagggcagccttcatccacagatgctcctaaggcttggaattatgaattgcctgcaacaaattatgagacccaagactcccataaagctggacccattggcattctctttgaactagtgcatatctttctctatgtggtacagccgcgtgatttcccagaagatactttgagaaaattcttacagaaggcatatgaatccaaaattgattatgacaagattgtctactatgaagcagggattattctatgctgtgtcctggggctgctgtttattattctgatgcctctggtggggtatttcttttgtatgtgtcgttgctgtaacaaatgtggtggagaaatgcaccagcgacagaaggaaaatgggcccttcctgaggaaatgctttgcaatctccctgttggtgatttgtataataataagcattggcatcttctatggttttgtggcaaatcaccaggtaagaacccggatcaaaaggagtcggaaactggcagatagcaatttcaaggacttgcgaactctcttgaatgaaactccagagcaaatcaaatatatattggcccagtacaacactaccaaggacaaggcgttcacagatctgaacagtatcaattcagtgctaggaggcggaattcttgaccgactgagacccaacatcatccctgttcttgatgagattaagtccatggcaacagcgatcaaggagaccaaagaggcgttggagaacatgaacagcaccttgaagagcttgcaccaacaaagtacacagcttagcagcagtctgaccagcgtgaaaactagcctgcggtcatctctcaatgaccctctgtgcttggtgcatccatcaagtgaaacctgcaacagcatcagattgtctctaagccagctgaatagcaaccctgaactgaggcagcttccacccgtggatgcagaacttgacaacgttaataacgttcttaggacagatttggatggcctggtccaacagggctatcaatcccttaatgatatacctgacagagtacaacgccaaaccacgactgtcgtagcaggtatcaaaagggtcttgaattccattggttcagatatcgacaatgtaactcagcgtcttcctattcaggatatactctcagcattctctgtttatgttaataacactgaaagttacatccacagaaatttacctacattggaagagtatgattcatactggtggctgggtggcctggtcatctgctctctgctgaccctcatcgtgattttttactacctgggcttactgtgtggcgtgtgcggctatgacaggcatgccaccccgaccacccgaggctgtgtctccaacaccggaggcgtcttcctcatggttggagttggattaagtttcctcttttgctggatattgatgatcattgtggttcttacctttgtctttggtgcaaatgtggaaaaactgatctgtgaaccttacacgagcaaggaattattccgggttttggatacaccctacttactaaatgaagactgggaatactatctctctgggaagctatttaataaatcaaaaatgaagctcacttttgaacaagtttacagtgactgcaaaaaaaatagaggcacttacggcactcttcacctgcagaacagcttcaatatcagtgaacatctcaacattaatgagcatactggaagcataagcagtgaattggaaagtctgaaggtaaatcttaatatctttctgttgggtgcagcaggaagaaaaaaccttcaggattttgctgcttgtggaatagacagaatgaattatgacagctacttggctcagactggtaaatcccccgcaggagtgaatcttttatcatttgcatatgatctagaagcaaaagcaaacagtttgcccccaggaaatttgaggaactccctgaaaagagatgcacaaactattaaaacaattcaccagcaacgagtccttcctatagaacaatcactgagcactctataccaaagcgtcaagatacttcaacgcacagggaatggattgttggagagagtaactaggattctagcttctctggattttgctcagaacttcatcacaaacaatacttcctctgttattattgaggaaactaagaagtatgggagaacaataataggatattttgaacattatctgcagtggatcgagttctctatcagtgagaaagtggcatcgtgcaaacctgtggccaccgctctagatactgctgttgatgtctttctgtgtagctacattatcgaccccttgaatttgttttggtttggcataggaaaagctactgtatttttacttccggctctaatttttgcggtaaaactggctaagtactatcgtcgaatggattcggaggacgtgtacgatgatgttgaaactatacccatgaaaaacccatcacaacattgatagctgatgttgaaactgcttgagcatcaggatactcaaagtggaaaggatcacagatttttggtagtttctgggtctacaaggactttccaaatccaggagcaacgccagtggcaacgtagtgactcaggcgggcaccaaggcaacggcaccattggtctctgggtagtgctttaagaatgaacacaatcacgttatagtccatggtccatcactattcaaggatgactccctcccttcctgtctatttttgttttttacttttttacactgagtttctatttagacactacaacatatggggtgtttgttcccattggatgcatttctatcaaaactctatcaaatgtgatggctagattctaacatattgccatgtgtggagtgtgctgaacacacaccagtttacaggaaagatgcattttgtgtacagtaaacggtgtatataccttttgttaccacagagttttttaaacaaatgagtattataggactttcttctaaatgagctaaataagtcaccattgacttcttggtgctgttgaaaataatccattttcactaaaagtgtgtgaaacctacagcatattcttcacgcagagattttcatctattatactttatcaaagattggccatgttccacttggaaatggcatgcaaaagcaatcatagagaaacctgcgtaactccatctgacaaattcaaaagagagagagagatcttgagagagaaatgctgttcgttcaaaagtggagttgttttaacagatgccaattacggtgtacagtttaacagagttttctgttgcattaggataaacattaattggagtgcagctaacatgagtatcatcagactagtatcaagtgttctaaaatgaaatatgagaagatcctgtcacaattcttagatctggtgtccagcatggatgaaacctttgagtttggtccctaaatttgcatgaaagcacaaggtaaatattcatttgcttcaggagtttcatgttggatctgtcattatcaaaagtgatcagcaatgaagaactggtcggacaaaatttaacgttgatgtaatgaaattccagatgtaggcattccccccaggtcttttcatgtgcagattgcagttctgattcatttgaataaaaaggaacttggaaaacatg
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:8842 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:8842 -> Molecular function: GO:0042805 [actinin binding] evidence: IDA
GeneID:8842 -> Molecular function: GO:0045296 [cadherin binding] evidence: IPI
GeneID:8842 -> Biological process: GO:0010842 [retina layer formation] evidence: ISS
GeneID:8842 -> Biological process: GO:0045494 [photoreceptor cell maintenance] evidence: IMP
GeneID:8842 -> Biological process: GO:0060042 [retina morphogenesis in camera-type eye] evidence: IMP
GeneID:8842 -> Biological process: GO:0060219 [camera-type eye photoreceptor cell differentiation] evidence: IMP
GeneID:8842 -> Biological process: GO:0060219 [camera-type eye photoreceptor cell differentiation] evidence: ISS
GeneID:8842 -> Biological process: GO:0072112 [glomerular visceral epithelial cell differentiation] evidence: IMP
GeneID:8842 -> Biological process: GO:0072139 [glomerular parietal epithelial cell differentiation] evidence: IMP
GeneID:8842 -> Biological process: GO:2000768 [positive regulation of nephron tubule epithelial cell differentiation] evidence: IMP
GeneID:8842 -> Cellular component: GO:0001750 [photoreceptor outer segment] evidence: ISS
GeneID:8842 -> Cellular component: GO:0005615 [extracellular space] evidence: IEA
GeneID:8842 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
GeneID:8842 -> Cellular component: GO:0005887 [integral to plasma membrane] evidence: IEA
GeneID:8842 -> Cellular component: GO:0005903 [brush border] evidence: IEA
GeneID:8842 -> Cellular component: GO:0009986 [cell surface] evidence: IDA
GeneID:8842 -> Cellular component: GO:0016324 [apical plasma membrane] evidence: IEA
GeneID:8842 -> Cellular component: GO:0031528 [microvillus membrane] evidence: IEA
GeneID:8842 -> Cellular component: GO:0032420 [stereocilium] evidence: IEA
GeneID:8842 -> Cellular component: GO:0042622 [photoreceptor outer segment membrane] evidence: IDA
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DBCLS
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