LOCUS       NM_001183403             696 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C Dcp1p (DCP1), partial mRNA.
ACCESSION   NM_001183403
VERSION     NM_001183403.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 696)
  AUTHORS   Dujon,B., Albermann,K., Aldea,M., Alexandraki,D., Ansorge,W.,
            Arino,J., Benes,V., Bohn,C., Bolotin-Fukuhara,M., Bordonne,R.,
            Boyer,J., Camasses,A., Casamayor,A., Casas,C., Cheret,G.,
            Cziepluch,C., Daignan-Fornier,B., Dang,D.V., de Haan,M., Delius,H.,
            Durand,P., Fairhead,C., Feldmann,H., Gaillon,L., Kleine,K. et al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XV
  JOURNAL   Nature 387 (6632 SUPPL), 98-102 (1997)
   PUBMED   9169874
REFERENCE   3  (bases 1 to 696)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 696)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 696)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 696)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 696)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   8  (bases 1 to 696)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2010) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   9  (bases 1 to 696)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001147).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XV"
     gene            <1..>696
                     /gene="DCP1"
                     /locus_tag="YOL149W"
                     /gene_synonym="MRT2"
                     /db_xref="GeneID:854016"
     CDS             1..696
                     /gene="DCP1"
                     /locus_tag="YOL149W"
                     /gene_synonym="MRT2"
                     /experiment="EXISTENCE:direct assay:GO:0000290
                     deadenylation-dependent decapping of nuclear-transcribed
                     mRNA [PMID:11139489]"
                     /experiment="EXISTENCE:direct assay:GO:0000932 P-body
                     [PMID:12730603|PMID:23509072]"
                     /experiment="EXISTENCE:direct assay:GO:0003729 mRNA
                     binding [PMID:11139489]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:23706738]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:23706738|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0008047 enzyme
                     activator activity [PMID:16341225]"
                     /experiment="EXISTENCE:direct assay:GO:0098562 cytoplasmic
                     side of membrane [PMID:27146487]"
                     /experiment="EXISTENCE:direct assay:GO:0098745 RNA
                     decapping complex [PMID:12554866]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000932 P-body
                     [PMID:12730603]"
                     /experiment="EXISTENCE:physical interaction:GO:0098745 RNA
                     decapping complex [PMID:10508173]"
                     /note="Subunit of the Dcp1p-Dcp2p decapping enzyme
                     complex; decapping complex removes the 5' cap structure
                     from mRNAs prior to their degradation; enhances the
                     activity of catalytic subunit Dcp2p; regulated by DEAD box
                     protein Dhh1p; forms cytoplasmic foci upon DNA replication
                     stress"
                     /codon_start=1
                     /product="Dcp1p"
                     /protein_id="NP_014492.1"
                     /db_xref="GeneID:854016"
                     /db_xref="SGD:S000005509"
                     /translation="

MTGAATAAENSATQLEFYRKALNFNVIGRYDPKIKQLLFHTPHASLYKWDFKKDEWNKLEYQGVLAIYLRDVSQNTNLLPVSPQEVDIFDSQNGSNNIQVNNGSDNSNRNSSGNGNSYKSNDSLTYNCGKTLSGKDIYNYGLIILNRINPDNFSMGIVPNSVVNKRKVFNAEEDTLNPLECMGVEVKDELVIIKNLKHEVYGIWIHTVSDRQNIYELIKYLLENEPKDSFA"

     misc_feature    52..666
                     /gene="DCP1"
                     /locus_tag="YOL149W"
                     /gene_synonym="MRT2"
                     /note="mRNA decapping enzyme 1 (Dcp1); Region: Dcp1;
                     cd09804"
                     /db_xref="CDD:197362"
     misc_feature    order(52..57,67..69,73..78,85..90,118..120,124..126,
                     190..192,433..441,448..450,454..456)
                     /gene="DCP1"
                     /locus_tag="YOL149W"
                     /gene_synonym="MRT2"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:197362"
ORIGIN      

atgaccggagcagcaactgcagcagaaaactctgccacacagttagaattctatagaaaagctttgaatttcaacgttattgggagatacgatccaaaaataaagcaactactttttcacacaccacatgcgtcactgtataaatgggacttcaagaaggacgaatggaataaactagaatatcaaggtgttttggccatatatttgagagacgtctcgcaaaatacaaatcttctacccgtctccccacaagaagtagatatttttgattcacaaaatggtagtaataacattcaagtaaacaatggttctgacaatagcaacaggaatagcagtggaaatgggaactcttataaaagtaatgattcgctaacatataattgcggcaaaactttaagtggaaaggacatatacaattatggattgatcatattaaaccgaattaatcctgacaatttttctatgggcattgttcccaatagtgtcgtaaataaaagaaaagtatttaatgcagaagaggatacacttaacccactagagtgcatgggggtagaggtgaaagatgaattggtcattattaagaacttgaagcatgaggtctatggtatatggattcatacagttagtgatagacaaaatatctacgaactaataaaatatcttctggaaaatgagccaaaagattcttttgcttga

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