LOCUS       NM_001182385            1158 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C Yox1p (YOX1), partial mRNA.
ACCESSION   NM_001182385
VERSION     NM_001182385.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 1158)
  AUTHORS   Bowman,S., Churcher,C., Badcock,K., Brown,D., Chillingworth,T.,
            Connor,R., Dedman,K., Devlin,K., Gentles,S., Hamlin,N., Hunt,S.,
            Jagels,K., Lye,G., Moule,S., Odell,C., Pearson,D., Rajandream,M.,
            Rice,P., Skelton,J., Walsh,S., Whitehead,S. and Barrell,B.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII
  JOURNAL   Nature 387 (6632 SUPPL), 90-93 (1997)
   PUBMED   9169872
REFERENCE   3  (bases 1 to 1158)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 1158)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1158)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1158)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (bases 1 to 1158)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001145).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XIII"
     gene            <1..>1158
                     /gene="YOX1"
                     /locus_tag="YML027W"
                     /db_xref="GeneID:854981"
     CDS             1..1158
                     /gene="YOX1"
                     /locus_tag="YML027W"
                     /experiment="EXISTENCE:direct assay:GO:0000785 chromatin
                     [PMID:12464632]"
                     /experiment="EXISTENCE:direct assay:GO:0000977 RNA
                     polymerase II transcription regulatory region
                     sequence-specific DNA binding
                     [PMID:20385087|PMID:12464633]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:15282802|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0043565
                     sequence-specific DNA binding [PMID:19158363]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000082 G1/S
                     transition of mitotic cell cycle [PMID:12464633]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:12464633]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000082 G1/S
                     transition of mitotic cell cycle
                     [PMID:17314407|PMID:12464633]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:17314407|PMID:12464633]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000977 RNA
                     polymerase II transcription regulatory region
                     sequence-specific DNA binding [PMID:12464633]"
                     /note="Homeobox transcriptional repressor; binds to Mcm1p
                     and to early cell cycle boxes (ECBs) in the promoters of
                     cell cycle-regulated genes expressed in M/G1 phase;
                     expression is cell cycle-regulated; phosphorylated by
                     Cdc28p; relocalizes from nucleus to cytoplasm upon DNA
                     replication stress; YOX1 has a paralog, YHP1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Yox1p"
                     /protein_id="NP_013685.1"
                     /db_xref="GeneID:854981"
                     /db_xref="SGD:S000004489"
                     /translation="

MSQETKMLPSLSSLLSGTEISSSPVSPSFTNPRTSFHLDDRGTIKLPPLNTSINRPRSVESALRHTVTSLHENSSAYGDDMLKHTQSDSALSSQLNSSQETVDESHENLLLTPLNSKKRDYSVSSKKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQRIATSKSTTIIQTVSPPSPPLDVHATPLASRVKADILRDGSSCSRSSSSSPLENTPPRPHHSLNRRSSTPSIKRSQALTFHLNPQKKTLTPVKTSPNSRVNKLINSIDHSPSKAKRPVSNPSGSPKRKRKFGFKIVDQQPLKDLDPNAFRG"

     misc_feature    376..801
                     /gene="YOX1"
                     /locus_tag="YML027W"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
ORIGIN      

atgtcacaagaaacaaaaatgctaccttctctatctagtcttctatcgggaaccgaaatctcgtccagccccgtatcaccaagcttcactaatccaagaacgagttttcacctcgatgatcgcggaaccataaaattaccaccgctaaacaccagtatcaatcgtccaagatctgtggaaagcgccttgagacacactgttacatccttgcatgaaaatagcagcgcttatggtgatgacatgctcaagcacacgcaatcagactcagccctctcatctcagttgaatagttctcaagaaacagttgatgaatcacacgaaaaccttctactgactcccctaaatagcaaaaagagagattattcggtttcttcaaagaaaaacgacatattaacaccactctctgcagcgaagtcgattattatcccctctgcctctaaggaaaaaagacgtgcatttgctttcatcacacactcgcaggagaccttccctaagaaggagcctaagatcgacaacgctccactagcacgccgaaagagaagaagaacctcgtcccaggaactatctattcttcaggctgaatttgaaaaatgtcctgctccatcgaaggagaaacgaattgagttagctgaatcttgccatatgactgaaaaagccgttcaaatatggttccagaataaaagacaagcggttaaaaggcagagaatcgccacttcgaagtcaaccactataatacaaacggtatctccaccatctccgcctctggacgttcatgctacgccactagcatccagagtcaaggcggacatacttcgtgatggaagctcatgttctcgttcttcctcttcttcaccgctggaaaatacgccgccaaggcctcatcattccctaaataggcgctcatccacaccaagcataaagagaagccaggctttaacattccatctaaacccacaaaagaagacgttgactcccgtgaaaacgtctcccaacagcagagtaaataaattgatcaatagcatagatcattctccatccaaagccaagcgtccggtaagcaatccctccggctcccctaaaaggaagagaaaattcggattcaagatcgtcgatcaacaaccgttgaaggatcttgatccgaacgctttccgtggttga

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