LOCUS       NM_001182068             993 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C Vta1p (VTA1), partial mRNA.
ACCESSION   NM_001182068
VERSION     NM_001182068.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 993)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 993)
  AUTHORS   Johnston,M., Hillier,L., Riles,L., Albermann,K., Andre,B.,
            Ansorge,W., Benes,V., Bruckner,M., Delius,H., Dubois,E.,
            Dusterhoft,A., Entian,K.D., Floeth,M., Goffeau,A., Hebling,U.,
            Heumann,K., Heuss-Neitzel,D., Hilbert,H., Hilger,F., Kleine,K.,
            Kotter,P., Louis,E.J., Messenguy,F., Mewes,H.W., Hoheisel,J.D. et
            al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XII
  JOURNAL   Nature 387 (6632 SUPPL), 87-90 (1997)
   PUBMED   9169871
REFERENCE   3  (bases 1 to 993)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 993)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 993)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 993)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 993)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   8  (bases 1 to 993)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Sequence update by submitter
REFERENCE   9  (bases 1 to 993)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001144).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..993
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XII"
     gene            <1..>993
                     /gene="VTA1"
                     /locus_tag="YLR181C"
                     /db_xref="GeneID:850878"
     CDS             1..993
                     /gene="VTA1"
                     /locus_tag="YLR181C"
                     /experiment="EXISTENCE:direct assay:GO:0001671 ATPase
                     activator activity [PMID:16505166|PMID:16601096]"
                     /experiment="EXISTENCE:direct assay:GO:0005768 endosome
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005771
                     multivesicular body [PMID:14701806]"
                     /experiment="EXISTENCE:direct assay:GO:0030674
                     protein-macromolecule adaptor activity [PMID:16505166]"
                     /experiment="EXISTENCE:genetic interaction:GO:0032511 late
                     endosome to vacuole transport via multivesicular body
                     sorting pathway [PMID:16505166]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0001671 ATPase
                     activator activity [PMID:16505166]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045324 late
                     endosome to vacuole transport [PMID:12953057]"
                     /note="Multivesicular body (MVB) protein; involved in
                     endosomal protein sorting; regulates Vps4p activity by
                     promoting its oligomerization; has an N-terminal Vps60-
                     and Did2- binding domain, a linker region, and a
                     C-terminal Vps4p binding domain"
                     /codon_start=1
                     /product="Vta1p"
                     /protein_id="NP_013282.1"
                     /db_xref="GeneID:850878"
                     /db_xref="SGD:S000004171"
                     /translation="

MASNAARVVATAKDFDKVGLGIIGYYLQLYAVELILSEEDRSQEMTALATELLDTIEAFKKEIGGESEAEDSDKSLHVMNTLIHDQEKAKIYMLNFTMSLYNEKLKQLKDGPWDVMLKRSLWCCIDLFSCILHLWKENISETSTNSLQKRIKYCKIYLSKLAKGEIGSSDEKTLDYADFADDSEEIKDEDVDHQTSDLENNNNDKVEGLAPKDQTTSYEPVDEVPEFIDDADSVNEEEQTVDKNEDAITKDEQQVVKKEVDLTRPSAPSEPAAAEHKSYTKDELTKIMDRASKIEQIQKLAKYAISALNYEDLPTAKDELTKALDLLNSI"

     misc_feature    28..483
                     /gene="VTA1"
                     /locus_tag="YLR181C"
                     /note="Vta1 like; Region: Vta1; pfam04652"
                     /db_xref="CDD:461380"
     misc_feature    880..984
                     /gene="VTA1"
                     /locus_tag="YLR181C"
                     /note="Vta1 C-terminal domain; Region: Vta1_C; pfam18097"
                     /db_xref="CDD:465647"
ORIGIN      

atggctagtaacgctgcaagggttgtcgctacagcgaaggattttgacaaagttgggttagggatcatcggatactatcttcagttatatgcggtggaattgatactgagtgaagaagatcggtcgcaagagatgaccgcactagcgacagaacttcttgatactattgaagcgtttaagaaggagattggcggcgagagtgaagcagaagacagtgacaaaagcttacacgttatgaacacgctaatacatgatcaagaaaaagccaaaatttatatgctaaattttacaatgtcgttgtataacgagaaactgaaacagctaaaagatggtccctgggatgttatgttaaaaagatcactttggtgttgtattgatttattttcatgcattttacacctgtggaaggaaaatataagtgaaacgagtacaaattcattacaaaaacgaattaagtattgcaaaatttatttgagtaaattggcaaagggtgaaattggttccagcgacgagaaaacgttagattatgcagattttgcggatgatagcgaggagattaaggatgaagatgttgatcaccagacaagcgatttggaaaacaataataatgataaagtcgaaggcctagccccaaaagaccaaacaacatcatacgagcctgtggatgaggtacctgaatttattgatgatgccgatagcgtaaacgaagaagaacagaccgtcgacaagaacgaagatgcaataacaaaagacgaacaacaagttgtgaagaaagaagtggatcttacgcgcccttctgcaccatcagaacctgctgcagcagagcataaatcgtatacaaaggatgagttgacaaaaattatggacagggccagtaaaatagagcaaattcaaaaacttgccaaatacgccataagcgcattgaattatgaagacctgcccaccgccaaagatgagttaactaaggcgttggatctgttaaattctatttga

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