LOCUS       NM_001181538            1683 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C Set4p (SET4), partial mRNA.
ACCESSION   NM_001181538
VERSION     NM_001181538.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1683)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 1683)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (bases 1 to 1683)
  AUTHORS   Galibert,F., Alexandraki,D., Baur,A., Boles,E., Chalwatzis,N.,
            Chuat,J.C., Coster,F., Cziepluch,C., De Haan,M., Domdey,H.,
            Durand,P., Entian,K.D., Gatius,M., Goffeau,A., Grivell,L.A.,
            Hennemann,A., Herbert,C.J., Heumann,K., Hilger,F., Hollenberg,C.P.,
            Huang,M.E., Jacq,C., Jauniaux,J.C., Katsoulou,C.,
            Karpfinger-Hartl,L. et al.
  TITLE     Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
            X
  JOURNAL   EMBO J. 15 (9), 2031-2049 (1996)
   PUBMED   8641269
REFERENCE   4  (bases 1 to 1683)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1683)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1683)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (bases 1 to 1683)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001142).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1683
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="X"
     gene            <1..>1683
                     /gene="SET4"
                     /locus_tag="YJL105W"
                     /db_xref="GeneID:853339"
     CDS             1..1683
                     /gene="SET4"
                     /locus_tag="YJL105W"
                     /experiment="EXISTENCE:direct assay:GO:0006338 chromatin
                     remodeling [PMID:34625508]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1900407
                     regulation of cellular response to oxidative stress
                     [PMID:30082318]"
                     /note="Chromatin-associated protein involved in control of
                     stress response; regulates response to oxidative stress;
                     involved in control of gene repression in subtelomeric
                     chromatin; contains a SET domain; SET4 has a paralog,
                     SET3, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Set4p"
                     /protein_id="NP_012430.1"
                     /db_xref="GeneID:853339"
                     /db_xref="SGD:S000003641"
                     /translation="

MTSPESLSSRHIRQGRTYTTTDKVISRSSSYSSNSSMSKDYGDHTPLSVSSAASETLPSPQYMPIRTFNTMPTAGPTPLHLFQNDRGIFNHHSSSGSSKTASTNKRGIAAAVALATAATIPFPLKKQNQDDNSKVSVTHNESSKENKITPSMRAEDNKPKNGCICGSSDSKDELFIQCNKCKTWQHKLCYAFKKSDPIKRDFVCKRCDSDTKVQVNQVKPMIFPRKMGDERLFQFSSIVTTSASNTNQHQQSVNNIEEQPKKRQLHYTAPTTENSNSIRKKLRQEKLVVSSHFLKPLLNEVSSSNDTEFKAITISEYKDKYVKMFIDNHYDDDWVVCSNWESSRSADIEVRKSSNERDFGVFAADSCVKGELIQEYLGKIDFQKNYQTDPNNDYRLMGTTKPKVLFHPHWPLYIDSRETGGLTRYIRRSCEPNVELVTVRPLDEKPRGDNDCRVKFVLRAIRDIRKGEEISVEWQWDLRNPIWEIINASKDLDSLPDPDKFWLMGSIKTILTNCDCACGYLGHNCPITKIKNFSEEFMRNTKESLSNKSYFNTIMHNCKP"

     misc_feature    487..621
                     /gene="SET4"
                     /locus_tag="YJL105W"
                     /note="PHD finger superfamily; Region: PHD_SF; cl22851"
                     /db_xref="CDD:473978"
     misc_feature    order(523..534,544..546,604..606)
                     /gene="SET4"
                     /locus_tag="YJL105W"
                     /note="histone H3 binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:276966"
     misc_feature    1036..1581
                     /gene="SET4"
                     /locus_tag="YJL105W"
                     /note="SET domain (including post-SET domain) found in
                     Schizosaccharomyces pombe SET domain-containing protein 3
                     (SETD3) and similar proteins; Region: SET_SpSET3-like;
                     cd19183"
                     /db_xref="CDD:380960"
     misc_feature    order(1072..1077,1126..1128,1156..1158,1198..1221,
                     1270..1284,1306..1308,1381..1383,1414..1434)
                     /gene="SET4"
                     /locus_tag="YJL105W"
                     /note="putative active site [active]"
                     /db_xref="CDD:380960"
     misc_feature    order(1072..1077,1198..1209,1270..1284,1420..1422)
                     /gene="SET4"
                     /locus_tag="YJL105W"
                     /note="putative SAM binding site; other site"
                     /db_xref="CDD:380960"
ORIGIN      

atgacttcaccggaatcactatcttctcgtcatatcaggcaaggaaggacatacacaaccacagacaaggtcatatcgcggtcgtcgtcgtactcatctaatagttcaatgtctaaagattacggcgatcacacacccttgtccgtcagcagtgcagcttcagagacattaccctcacctcagtatatgccgataaggacattcaatacaatgcctacagctggcccaacgcctttacatttatttcaaaatgacaggggcattttcaaccatcattcttcatcaggctcatcaaaaacggcatcaacaaataaaagaggaatagcagcagcagtagcattggcaactgctgccaccataccatttccactgaaaaaacagaatcaagatgataattccaaggtctcggtaacacacaatgaatcatcgaaagaaaataaaattacaccctccatgagagcagaagataacaaacctaaaaatggttgcatctgcggttcaagtgactccaaggatgagttgtttatacagtgtaacaaatgtaaaacgtggcagcacaagttatgttatgctttcaaaaaatcagatccaataaaaagagattttgtttgcaaaagatgtgacagtgatacgaaagtgcaggttaatcaagtaaaaccaatgatattccctagaaaaatgggagatgagcgattatttcaattttcatccatagtgacaacttcagcatcgaacacaaatcagcatcaacagtctgtgaataacatagaggaacagcccaagaaacgtcaacttcattataccgccccaacaactgaaaatagcaatagtatacggaaaaaattgaggcaagaaaaactggtagtatcaagccactttctgaagccactactgaatgaggtaagttcttccaatgacacggaattcaaagcaataacaatatcagagtataaggacaaatatgttaagatgtttattgataaccattatgatgacgattgggttgtttgttctaactgggaaagctcaaggtcagctgacatcgaggtaagaaaatcatcaaatgaaagagattttggagtcttcgctgcagattcttgtgttaaaggtgagctaattcaagaatatttgggcaaaattgattttcaaaaaaattatcagacagatccaaataatgactatcgtttgatgggaacgacaaaacctaaagtactttttcatccacattggcctttatatatagactctcgagaaacaggcggattaacaagatacataagacggagttgtgagcccaatgtggaactagtaacggtaagaccgcttgacgaaaaaccaagaggagataatgattgtagagttaaatttgttttaagggctataagagatattcgtaagggagaagagataagcgtagaatggcaatgggatttgagaaatcctatttgggagataataaatgcatctaaagatttggattccctaccggatcccgacaagttctggttgatggggtcaataaagactattttaacaaattgtgattgtgcatgtgggtacttgggccataattgtccaataactaaaatcaaaaacttttctgaagaattcatgaggaatacgaaggaatccctatctaataaatcttactttaatacaataatgcacaactgtaagccataa

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