LOCUS       NM_001180425            1698 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C Tma64p (TMA64), partial mRNA.
ACCESSION   NM_001180425
VERSION     NM_001180425.3
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1698)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 1698)
  AUTHORS   Jacq,C., Alt-Morbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.,
            Bargues,M., Baron,L., Becker,A., Biteau,N., Blocker,H., Blugeon,C.,
            Boskovic,J., Brandt,P., Bruckner,M., Buitrago,M.J., Coster,F.,
            Delaveau,T., del Rey,F., Dujon,B., Eide,L.G.,
            Garcia-Cantalejo,J.M., Goffeau,A., Gomez-Peris,A., Zaccaria,P. et
            al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
  JOURNAL   Nature 387 (6632 SUPPL), 75-78 (1997)
   PUBMED   9169867
REFERENCE   3  (bases 1 to 1698)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 1698)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1698)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1698)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 1698)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   8  (bases 1 to 1698)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   9  (bases 1 to 1698)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001136).
            
            On Jul 30, 2012 this sequence version replaced NM_001180425.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1698
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="IV"
     gene            <1..>1698
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /db_xref="GeneID:851695"
     CDS             1..1698
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
                     [PMID:14759368]"
                     /experiment="EXISTENCE:physical interaction:GO:0006364
                     rRNA processing [PMID:14759368]"
                     /note="hypothetical protein that associates with
                     ribosomes; has a putative RNA binding domain; in mammals
                     the corresponding protein, eIF2D, has been shown to
                     possess translation initiation factor activity"
                     /codon_start=1
                     /product="Tma64p"
                     /protein_id="NP_010402.3"
                     /db_xref="GeneID:851695"
                     /db_xref="SGD:S000002524"
                     /translation="

MFKKEPHIKALSNLKNSERKKLLQTFQKQTNNEEYSFRTSTIKQTNFNGQKSVGTVYTDENNTPILFKEKHKEQLFPTVYSCWEYPALLPIVLTHGFVIEEHLFNGANLMISGSIPPFDPRCKIGTLCGIASKQAPETVLAIGIVELDLPSFDKVIGETGVAVKIIHHFNDGLSKVFKMKLEPPFVLSTQSKDNNISSKQIESSEQIKAVEKEQEDVKEASVDVEEIAEVLDHFTVSDVDYFITRALYYTLTQDKGLELPISASNFISNHIMRNLPPIDHNEVNVKKTSWKKSAKFLKHFEKEGFLKLKGKGDDLTIVGKNTDKDELKNFVPYKLGCSKSATESRESTTSKEKTSGMMYSLTLYKPFNLAKDLLKEVNLASHTYYTSQDIRSAVSQYISVKNLADTKDKGKVIMDDLLFDMVNKKKKVLNASRIIARGEILHPLLTNNFTEFYQIFKSDDTLLFKAPMKGSLPHIKIITEMKIGRKVITRVSNFEVFQVDPESLAADLRKICSGSTTISESQTFKCAEVQVQGPHGQSIIDHLNKLGIPSKWIDFENKLKKKKRK"

     misc_feature    4..258
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /note="Pre-PUA-like domain; Region: Pre-PUA; pfam17832"
                     /db_xref="CDD:436077"
     misc_feature    262..510
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /note="PUA RNA-binding domain of eukaryotic translation
                     initiation factor 2D and similar proteins; Region:
                     PUA_eIF2d-like; cd21156"
                     /db_xref="CDD:409298"
     misc_feature    order(289..294,304..306,319..324,328..330)
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:409298"
     misc_feature    1420..1668
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /note="C-terminal domain of eIF2D and related proteins;
                     Region: eIF2D_C; cd11608"
                     /db_xref="CDD:211321"
     misc_feature    order(1444..1446,1453..1458,1462..1464,1516..1518,
                     1525..1533,1537..1545,1549..1551,1594..1596,1603..1605)
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /note="putative rRNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:211321"
ORIGIN      

atgtttaagaaggagcctcacataaaagctttaagtaatttgaagaattccgaaagaaagaagttgctacaaacattccaaaaacaaacgaataatgaggaatatagctttcgtacttccactataaaacaaaccaactttaacggccagaaaagtgtaggaacggtttacacagatgagaataataccccaatattattcaaggaaaagcataaggagcaactttttccaactgtgtattcttgttgggaatatcctgcgttattgccgatcgttttaactcatggatttgttatagaagaacatttattcaacggcgctaacttaatgatttccggttcgatcccaccctttgatcctcgttgtaaaataggtactctttgtggtatagctagcaaacaggcaccagaaactgtcttagccatcggtattgtcgaattagatctaccgtcctttgataaagtaattggtgaaacaggagttgctgtcaaaatcatacatcatttcaatgatgggctctccaaagtctttaaaatgaaattggaacctccatttgttctcagtactcaatcaaaggataacaatatcagtagtaaacagatagaatcctcggagcaaatcaaggctgttgaaaaggaacaagaagatgtaaaagaagcgtctgttgatgtagaggagattgctgaagttctagaccatttcactgtgtcggatgtagattatttcattacaagagcattatattataccttgactcaagataaaggtttggaattacccatttcagcttctaacttcatctcaaaccacattatgcgtaatttgcctccaattgatcacaatgaagtcaatgtaaagaaaacttcatggaaaaaaagcgcaaaatttttgaaacacttcgagaaagaaggcttcttgaaattaaaaggaaagggggatgacttaactattgtgggcaaaaatactgacaaggatgagttaaagaactttgtgccatataagcttggttgtagcaagtctgccacagaaagtagggagagcacaacctcgaaggagaaaacatctggaatgatgtattcactgactctgtataaaccctttaatcttgccaaagatcttttgaaggaggttaatttggcttctcacacgtactacacctctcaggacattagaagcgcggtttctcagtatatttctgtcaagaacctagcagacacaaaagataaaggaaaagttattatggacgatctattattcgatatggtcaataagaagaagaaagtcttgaatgcttcacgtatcattgctagaggtgaaattttgcatcccttactcaccaataattttaccgagttctatcagatattcaaaagcgatgatactctcttgttcaaggcgccaatgaagggttcccttccgcatattaagattattactgaaatgaaaattggcagaaaagttattaccagagtgagcaattttgaagtgtttcaagtcgacccagaatcacttgcggctgacttaagaaagatttgtagcggatcgacaacaataagtgaatcacaaacattcaaatgtgctgaagtgcaggttcaaggtccacacggtcaatcgatcattgatcaccttaacaagctaggtattccaagcaaatggatagactttgagaacaagttgaagaagaaaaaaagaaagtag

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