LOCUS       NM_001180390            1485 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C Stn1p (STN1), partial mRNA.
ACCESSION   NM_001180390
VERSION     NM_001180390.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1485)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 1485)
  AUTHORS   Jacq,C., Alt-Morbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.,
            Bargues,M., Baron,L., Becker,A., Biteau,N., Blocker,H., Blugeon,C.,
            Boskovic,J., Brandt,P., Bruckner,M., Buitrago,M.J., Coster,F.,
            Delaveau,T., del Rey,F., Dujon,B., Eide,L.G.,
            Garcia-Cantalejo,J.M., Goffeau,A., Gomez-Peris,A., Zaccaria,P. et
            al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
  JOURNAL   Nature 387 (6632 SUPPL), 75-78 (1997)
   PUBMED   9169867
REFERENCE   3  (bases 1 to 1485)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 1485)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1485)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1485)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 1485)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   8  (bases 1 to 1485)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   9  (bases 1 to 1485)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001136).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1485
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="IV"
     gene            <1..>1485
                     /gene="STN1"
                     /locus_tag="YDR082W"
                     /db_xref="GeneID:851655"
     CDS             1..1485
                     /gene="STN1"
                     /locus_tag="YDR082W"
                     /experiment="EXISTENCE:direct assay:GO:0043047
                     single-stranded telomeric DNA binding [PMID:17293872]"
                     /experiment="EXISTENCE:direct assay:GO:0061770 translation
                     elongation factor binding [PMID:31006804]"
                     /experiment="EXISTENCE:genetic interaction:GO:0016233
                     telomere capping [PMID:9042864|PMID:15132993]"
                     /experiment="EXISTENCE:genetic interaction:GO:0032211
                     negative regulation of telomere maintenance via telomerase
                     [PMID:17947422]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016233
                     telomere capping [PMID:15132993|PMID:9042864]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032211
                     negative regulation of telomere maintenance via telomerase
                     [PMID:17947422]"
                     /experiment="EXISTENCE:physical interaction:GO:0016233
                     telomere capping [PMID:15132993|PMID:9042864]"
                     /experiment="EXISTENCE:physical interaction:GO:1990879 CST
                     complex [PMID:11230140|PMID:9042864]"
                     /note="Telomere end-binding and capping protein; plays a
                     key role with Pol12p in linking telomerase action with
                     completion of lagging strand synthesis, and in a
                     regulatory step required for telomere capping; similar to
                     human Stn1"
                     /codon_start=1
                     /product="Stn1p"
                     /protein_id="NP_010367.1"
                     /db_xref="GeneID:851655"
                     /db_xref="SGD:S000002489"
                     /translation="

MDKYGHIAHQEGDVCYYIPRLFKYNSYYSGTEDVRIFVGDLKYRMRVSLQICEKYYDRRLSMLFWKNHPLQQIHLIGCIIGLQFKWIGKQEYIFFQLDDCTSDSSLVGYTSDMRFLTCKVKKDSILSWGLNITDLIGLTLHVYGQASLNYQELQVEYLRLCYSLTEEIDHWKITMNMREQLDTPWSLSDFVIGELFTQEQEWTPETSQIEVVNPDFVGIGYKTPESKRNETTFIEQLQEERLKDELEIISPYNSTDTSNSVHSLSFRFVSSLKDFPETHFLNSGDQIDNGNDEQLKKLEYQSANLPVMIPNRTSAKSNLMLILLGLQMKEISNSDLYKLKEVRSVVTSLASFLFQQQNVGVMKSFDSLEKEAFRDLVNRLVSQGLIGLKDKTSETFDLLPLKNLFEYAEKRISVLMKLQCYTGTVQLSHVQEKLHLPYITTNGIVDVFKECLKRTKKQYPEVLKNWWIDLDPKNGMEDQNSGILLHLEYAAAYS"

     misc_feature    31..783
                     /gene="STN1"
                     /locus_tag="YDR082W"
                     /note="Telomere regulation protein Stn1; Region: Stn1;
                     pfam10451"
                     /db_xref="CDD:371062"
     misc_feature    955..1467
                     /gene="STN1"
                     /locus_tag="YDR082W"
                     /note="Telomere capping C-terminal wHTH; Region: Stn1_C;
                     pfam12659"
                     /db_xref="CDD:463659"
ORIGIN      

atggataagtacggacatatagctcatcaagaaggcgatgtttgttattatattccaaggctgttcaaatacaacagttattatagtgggacagaggacgttcgaatatttgttggagatttaaagtaccggatgagagtttctttgcaaatttgcgaaaagtattatgataggcggttgtcgatgttgttctggaaaaatcatcctttacagcaaatacaccttattggctgcatcattggactccagttcaaatggattgggaaacaagaatacattttttttcagttggacgattgtacttcagactcttcattggtgggttatactagtgacatgagattcttaacatgtaaagttaagaaggatagcatcctatcatgggggttgaacataaccgatttgataggcttaactcttcatgtctacgggcaagcaagtttgaactatcaagagcttcaagttgaatatttaagattatgctacagtttaacggaagaaatagatcattggaaaatcacaatgaacatgcgtgagcaacttgacacgccttggtccttaagcgattttgtaattggagaattgttcacgcaagagcaagagtggacacctgagacatcacagattgaggtagtaaacccggattttgtaggtatagggtacaaaaccccagaaagtaaaagaaatgaaactactttcatcgagcaactgcaagaagaacgcttgaaggatgaattagaaattattagtccatacaatagcacagatacttcgaatagtgtgcattccttgtcatttcggtttgtatcgtcgctaaaggattttcctgaaactcactttttgaattcaggtgatcaaattgacaacggcaatgacgaacagttaaaaaaactagaatatcaaagcgctaatctacctgtgatgattcccaataggacatcagcaaagtcaaacttgatgttgatcctattaggactacaaatgaaagagatttctaattctgacctttacaaactaaaggaagtacgcagcgtagtaactagcttagcatcgtttttgtttcaacaacaaaatgttggcgtcatgaaatcttttgactctttggaaaaggaagcgtttcgagacctggttaatcgtctagtcagccagggtttgatcggattaaaagataaaacaagtgagacatttgatttgcttcctctaaaaaatctttttgaatatgctgaaaaacgtatatcagttctaatgaagctacaatgttatacaggcactgtgcaattaagtcatgttcaggaaaagctacatttgccgtacataacaacgaacggcatcgttgatgttttcaaagaatgtcttaaaaggacaaagaaacagtatcctgaggtactaaaaaattggtggattgatcttgatccgaagaatggtatggaggaccaaaacagtggaatattattacatttggaatacgcagcagcatattcataa

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