2024-11-01 07:57:05, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_001414936 3635 bp mRNA linear ROD 31-MAR-2024 DEFINITION Rattus norvegicus RAS protein activator like 3 (Rasal3), transcript variant 1, mRNA. ACCESSION NM_001414936 XM_006241059 VERSION NM_001414936.1 KEYWORDS RefSeq; RefSeq Select. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 (bases 1 to 3635) AUTHORS Saito,S., Kawamura,T., Higuchi,M., Kobayashi,T., Yoshita-Takahashi,M., Yamazaki,M., Abe,M., Sakimura,K., Kanda,Y., Kawamura,H., Jiang,S., Naito,M., Yoshizaki,T., Takahashi,M. and Fujii,M. TITLE RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells JOURNAL Eur J Immunol 45 (5), 1512-1523 (2015) PUBMED 25652366 REFERENCE 2 (bases 1 to 3635) AUTHORS Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M. and Stoorvogel,W. TITLE MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis JOURNAL Immunol Cell Biol 88 (8), 851-856 (2010) PUBMED 20458337 REFERENCE 3 (bases 1 to 3635) AUTHORS Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A. TITLE Defining the membrane proteome of NK cells JOURNAL J Mass Spectrom 45 (1), 1-25 (2010) PUBMED 19946888 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAXUCZ010000007.1. On Dec 15, 2022 this sequence version replaced XM_006241059.4. ##Evidence-Data-START## Transcript exon combination :: SRR26643292.28658.1, SRR26643284.9761.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-501 JAXUCZ010000007.1 12061383-12061883 c 502-641 JAXUCZ010000007.1 12057942-12058081 c 642-720 JAXUCZ010000007.1 12057737-12057815 c 721-782 JAXUCZ010000007.1 12057581-12057642 c 783-853 JAXUCZ010000007.1 12054461-12054531 c 854-980 JAXUCZ010000007.1 12053947-12054073 c 981-1079 JAXUCZ010000007.1 12053766-12053864 c 1080-1616 JAXUCZ010000007.1 12052826-12053362 c 1617-1761 JAXUCZ010000007.1 12052238-12052382 c 1762-1906 JAXUCZ010000007.1 12051463-12051607 c 1907-2143 JAXUCZ010000007.1 12050446-12050682 c 2144-2345 JAXUCZ010000007.1 12050148-12050349 c 2346-2464 JAXUCZ010000007.1 12049938-12050056 c 2465-2855 JAXUCZ010000007.1 12048793-12049183 c 2856-3013 JAXUCZ010000007.1 12048438-12048595 c 3014-3077 JAXUCZ010000007.1 12047748-12047811 c 3078-3635 JAXUCZ010000007.1 12047090-12047647 c FEATURES Location/Qualifiers source 1..3635 /organism="Rattus norvegicus" /mol_type="mRNA" /strain="BN" /db_xref="taxon:10116" /chromosome="7" /map="7q11" gene 1..3635 /gene="Rasal3" /gene_synonym="RGD1309019" /note="RAS protein activator like 3" /db_xref="GeneID:314596" /db_xref="RGD:1309019" exon 1..501 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" CDS 117..3233 /gene="Rasal3" /gene_synonym="RGD1309019" /note="isoform 1 is encoded by transcript variant 1" /codon_start=1 /product="RAS protein activator like-3 isoform 1" /protein_id="NP_001401865.1" /db_xref="GeneID:314596" /db_xref="RGD:1309019" /translation="
MKTECGQTTRRSVTFWSCSRDSAMDPPLQNEDSQTQPSPLTSYRWHTGGRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNRLRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFALLEGRLVMLGEEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLSELDLGVERDVRVWPLHPSLLGEPYCFQVTWAGGSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAAPGVRAELWLDGALLARTAPRAGPDQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELERCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDPSKCPTPELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTRDSLEPLPTILQAIEEGRPVPVSVPMRLPLNTAHVQSSFSSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWARRRPDGERPQRRPRPVLRTQSVPARRPTHHRPAAGSKPRPKGSLRTGPATSGRAWARTSTSLPRKPSVPWQRQLDQPGDRYQTPGTHRPVGKLAEIQCEVAALREEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLGLKSLEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVNGADLSMGT"
misc_feature 714..1154 /gene="Rasal3" /gene_synonym="RGD1309019" /note="Pleckstrin homology-like domain; Region: PH-like; cl17171" /db_xref="CDD:473070" misc_feature 1071..1469 /gene="Rasal3" /gene_synonym="RGD1309019" /note="C2 domain; Region: C2; cl14603" /db_xref="CDD:472691" misc_feature 1443..2414 /gene="Rasal3" /gene_synonym="RGD1309019" /note="Ras-GTPase Activating Domain of DAB2IP and similar proteins; Region: RasGAP_DAB2IP; cd05136" /db_xref="CDD:213338" misc_feature order(1560..1562,1671..1673,1677..1679,1683..1688, 1692..1694,1701..1703,1713..1715,1989..1991,2013..2018, 2025..2030,2037..2039,2100..2102,2109..2114,2121..2123, 2133..2135,2139..2141,2154..2159) /gene="Rasal3" /gene_synonym="RGD1309019" /note="putative RAS interface [polypeptide binding]; other site" /db_xref="CDD:213338" exon 502..641 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 642..720 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 721..782 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 783..853 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 854..980 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 981..1079 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 1080..1616 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 1617..1761 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 1762..1906 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 1907..2143 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2144..2345 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2346..2464 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2465..2855 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2856..3013 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 3014..3077 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 3078..3635 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" ORIGIN
acagacggctgctggttctggactggccaggaaatcaaggtaagagagggtgtacgtgtggcaccctcaagtgtgttctgtcctttggaggcaaagctgagaagagactggggaagatgaagacagaatgtgggcagacaacgcgcagaagtgtcaccttttggtcttgtagcagagactccgccatggacccaccgctgcagaatgaagattcccaaacgcagccctcgccgctgacgtcctatcgttggcacactggaggcagaggggagaagattgctggagggttccgctggggccgcttcgcaggctggggaagggccctgagccatcaggagcccatggtgagcagccagccagcccctagatctctgtttcgtcgggtcctctctgcacctcctaaggagtcacgacccaatcgcctccggttttccaagagcctgtgggggaggcacaagaacgtggtaccgctggaacccaagctaaatccgaaggccccagagccagagctggagttggagggagccccagacctgcgcgctgcacatatccctgagcctcccgcccctgacatgcctgtttggaacattgatggctttgccctgctcgaaggaagactggtgatgctcggtgaggaggagggtcctcgccaaatccgaatgggaagtgccagctcggaaagcagcatgcaggcagccttggggaacctcaaagacccagttcggactcctgggaaaattgagccggaagctactggttccaaccaggtccacaatgttcggaagttactcaagaggctgaaggagaagaaaagggccaagtcggaactgggagcccacactcctcgagatggaccctccagtgctcttggttccagagaatcgctggccacactctctgagctggacctaggcgttgagagggatgtgagagtctggccgctgcatcctagcctcctgggggagccatattgcttccaggtaacgtgggcaggtgggagccgctgtttctcttgtcgctcgagcgctgagagagaccgttggattgaggaccttcgtcggcagttccagcctagccaggacaatgtggaacgacaagagacctggctgacagtgtgggtgcacgaagccaaagggcttccccgagcagctgcacccggagtgcgtgcggagctgtggttggacggcgcgctactggcgcgcactgcccctcgggcgggccctgaccaactcttctgggccgaacgcttccacttcgaggcgttgccacctgcccgtcgcctgtcgctgcggctgcgcggagcaggcccggcaggggcaaccgtgggcagggtggtactagaactggacgaggtgagcatcccccgcgcgcctgccgcaggcctggagcgctggttccccgtgctcggggctccggcgggtgcggtgctacgggcgcggatcagggtacgatgtctgcgcgtgctgccgtcggagcgctataaggagttagcggagttcctcaccttccactacgcgcgcctgtgcatggcgctggagcccgcgctgtctgctcaggccaaggaggagctggcagcagccatggtgcgcgtgctacgagccactggccgagcgcaggcattggtgacagacctaggaaccgcagagctggagcgctgtggaggccgtgaagcgctgctattccgagaaaataccttagccacaaaggccattgatgaatacatgaaactggtggcacaggagtacctccaggagaccctgggccaggttgtgcggagtctctgtgcctccaccgaggactgtgaagtggaccccagcaagtgcccaacaccggagctgccaaaatgccaagctagactgcgaagcagttgtgaggaggtttttgaaaacatcatccactcttacaactatttcccagcagagctgggcaccgtgttctcaaattggcgggaagcatgcaaagcacgaggctctgaggcactgggcccccggctggtgtgtgcttctctcttcctaaggctcctatgccccgccatcttggcacctagcctctttggcctggcaccagagcaccccgccccaggcccagccagaactcttacactcatcgccaaggtcatccagaatcttgccaactgtgctccgtttggtgagaaggaagcctacatggtctttatgaatagcttcctggaagatcatggaccggccatgcgacacttcctggatcaggtagctatggtggacacagataccacacccagtggctaccagggaagtggagacctggccctccagttggcagttcttcatgtccagctctgcacaatctttgctgaacttgaccagaaaactcgagacagcttggaaccactacccaccatccttcaagccattgaggagggtcggcctgtcccagtgtctgtaccaatgcgtcttcccctgaacactgctcatgtccaatccagcttctcttcaggggagaaacccggcttcctggcaccccgagacctccccaagcacactcctctcatttccaagagccagtctttgcgcagctttcaaggggcaggaagctgggcccgtcggcggccagatggggagcggccccagcggcggccgcggccagtgctgcgcacacagagcgtccctgccagacgccctacccaccatcgccctgctgcgggttccaagcctcgacccaaaggctctctacgcactggtcctgcgacttccggacgggcctgggctaggacttccacctctctacctcggaagccatcggtgccttggcagcgccaactggaccagcccggggaccgataccaaactccgggaacgcaccgaccagtgggcaagctagcagagatacaatgcgaggtagctgcactccgcgaggaacagaaagccctgtcccatctggtggagtcgctgagtacccacatccaggccttgacggagcagcaagagcagctccgctgtcagctgcaggatctggactccagactgggagctgggatctcaaagttggattctaagggtggtctcccaagcaacggtagcctcgggctgaaaagtctggagcaccgcatgactgagatggaatgttctcagaaccagctgagggataccctccaaagcctacagcttctttcaaaaactccaggatctcggagccagcccccgcctctcaaagcaccatgtgtcaatggagctgatctgtcgatgggcacctgagtatttcaccccactccatacagtctggaagccaggagagccactacagaggattttctgactacctcagtccttcatggcccttagtaggggacagagtgggaggtgtcaatcactctggtaactgtgaggttgcccagtaaatctccatttcagaaaatcactggtttctctgcccctacaaagattaatgcaagagcatacccagttctctactcagctcccccaaattcttacctaatttgaagtctcccgaagatgaaaatgattagcaaaattgtcctcactattggtgtgatctaaggtcatcactctaaaagactccattctctcttctgtatctaaaaattctctgcatagttaaaggtattcaataaaaggtatttatcattgttgtgggaa
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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