2024-11-01 08:23:59, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_001134562 3502 bp mRNA linear ROD 31-MAR-2024 DEFINITION Rattus norvegicus RAS protein activator like 3 (Rasal3), transcript variant 2, mRNA. ACCESSION NM_001134562 XM_001077947 XM_234839 VERSION NM_001134562.3 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 (bases 1 to 3502) AUTHORS Saito,S., Kawamura,T., Higuchi,M., Kobayashi,T., Yoshita-Takahashi,M., Yamazaki,M., Abe,M., Sakimura,K., Kanda,Y., Kawamura,H., Jiang,S., Naito,M., Yoshizaki,T., Takahashi,M. and Fujii,M. TITLE RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells JOURNAL Eur J Immunol 45 (5), 1512-1523 (2015) PUBMED 25652366 REFERENCE 2 (bases 1 to 3502) AUTHORS Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M. and Stoorvogel,W. TITLE MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis JOURNAL Immunol Cell Biol 88 (8), 851-856 (2010) PUBMED 20458337 REFERENCE 3 (bases 1 to 3502) AUTHORS Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A. TITLE Defining the membrane proteome of NK cells JOURNAL J Mass Spectrom 45 (1), 1-25 (2010) PUBMED 19946888 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAXUCZ010000007.1. On Dec 15, 2022 this sequence version replaced NM_001134562.2. ##Evidence-Data-START## Transcript exon combination :: SRR26643295.27401.1, SRR26643284.9762.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386 [ECO:0006172] ##Evidence-Data-END## COMPLETENESS: full length. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-39 JAXUCZ010000007.1 12061845-12061883 c 40-368 JAXUCZ010000007.1 12061383-12061711 c 369-508 JAXUCZ010000007.1 12057942-12058081 c 509-587 JAXUCZ010000007.1 12057737-12057815 c 588-649 JAXUCZ010000007.1 12057581-12057642 c 650-720 JAXUCZ010000007.1 12054461-12054531 c 721-847 JAXUCZ010000007.1 12053947-12054073 c 848-946 JAXUCZ010000007.1 12053766-12053864 c 947-1483 JAXUCZ010000007.1 12052826-12053362 c 1484-1628 JAXUCZ010000007.1 12052238-12052382 c 1629-1773 JAXUCZ010000007.1 12051463-12051607 c 1774-2010 JAXUCZ010000007.1 12050446-12050682 c 2011-2212 JAXUCZ010000007.1 12050148-12050349 c 2213-2331 JAXUCZ010000007.1 12049938-12050056 c 2332-2722 JAXUCZ010000007.1 12048793-12049183 c 2723-2880 JAXUCZ010000007.1 12048438-12048595 c 2881-2944 JAXUCZ010000007.1 12047748-12047811 c 2945-3502 JAXUCZ010000007.1 12047090-12047647 c FEATURES Location/Qualifiers source 1..3502 /organism="Rattus norvegicus" /mol_type="mRNA" /strain="BN" /db_xref="taxon:10116" /chromosome="7" /map="7q11" gene 1..3502 /gene="Rasal3" /gene_synonym="RGD1309019" /note="RAS protein activator like 3" /db_xref="GeneID:314596" /db_xref="RGD:1309019" exon 1..39 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 40..368 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" CDS 53..3100 /gene="Rasal3" /gene_synonym="RGD1309019" /note="isoform 2 is encoded by transcript variant 2" /codon_start=1 /product="RAS protein activator like-3 isoform 2" /protein_id="NP_001128034.1" /db_xref="GeneID:314596" /db_xref="RGD:1309019" /translation="
MDPPLQNEDSQTQPSPLTSYRWHTGGRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNRLRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFALLEGRLVMLGEEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLSELDLGVERDVRVWPLHPSLLGEPYCFQVTWAGGSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAAPGVRAELWLDGALLARTAPRAGPDQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELERCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDPSKCPTPELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTRDSLEPLPTILQAIEEGRPVPVSVPMRLPLNTAHVQSSFSSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWARRRPDGERPQRRPRPVLRTQSVPARRPTHHRPAAGSKPRPKGSLRTGPATSGRAWARTSTSLPRKPSVPWQRQLDQPGDRYQTPGTHRPVGKLAEIQCEVAALREEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLGLKSLEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVNGADLSMGT"
misc_feature 581..1021 /gene="Rasal3" /gene_synonym="RGD1309019" /note="Pleckstrin homology-like domain; Region: PH-like; cl17171" /db_xref="CDD:473070" misc_feature 938..1336 /gene="Rasal3" /gene_synonym="RGD1309019" /note="C2 domain; Region: C2; cl14603" /db_xref="CDD:472691" misc_feature 1310..2281 /gene="Rasal3" /gene_synonym="RGD1309019" /note="Ras-GTPase Activating Domain of DAB2IP and similar proteins; Region: RasGAP_DAB2IP; cd05136" /db_xref="CDD:213338" misc_feature order(1427..1429,1538..1540,1544..1546,1550..1555, 1559..1561,1568..1570,1580..1582,1856..1858,1880..1885, 1892..1897,1904..1906,1967..1969,1976..1981,1988..1990, 2000..2002,2006..2008,2021..2026) /gene="Rasal3" /gene_synonym="RGD1309019" /note="putative RAS interface [polypeptide binding]; other site" /db_xref="CDD:213338" exon 369..508 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 509..587 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 588..649 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 650..720 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 721..847 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 848..946 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 947..1483 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 1484..1628 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 1629..1773 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 1774..2010 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2011..2212 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2213..2331 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2332..2722 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2723..2880 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2881..2944 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" exon 2945..3502 /gene="Rasal3" /gene_synonym="RGD1309019" /inference="alignment:Splign:2.1.0" ORIGIN
acagacggctgctggttctggactggccaggaaatcaagcagagactccgccatggacccaccgctgcagaatgaagattcccaaacgcagccctcgccgctgacgtcctatcgttggcacactggaggcagaggggagaagattgctggagggttccgctggggccgcttcgcaggctggggaagggccctgagccatcaggagcccatggtgagcagccagccagcccctagatctctgtttcgtcgggtcctctctgcacctcctaaggagtcacgacccaatcgcctccggttttccaagagcctgtgggggaggcacaagaacgtggtaccgctggaacccaagctaaatccgaaggccccagagccagagctggagttggagggagccccagacctgcgcgctgcacatatccctgagcctcccgcccctgacatgcctgtttggaacattgatggctttgccctgctcgaaggaagactggtgatgctcggtgaggaggagggtcctcgccaaatccgaatgggaagtgccagctcggaaagcagcatgcaggcagccttggggaacctcaaagacccagttcggactcctgggaaaattgagccggaagctactggttccaaccaggtccacaatgttcggaagttactcaagaggctgaaggagaagaaaagggccaagtcggaactgggagcccacactcctcgagatggaccctccagtgctcttggttccagagaatcgctggccacactctctgagctggacctaggcgttgagagggatgtgagagtctggccgctgcatcctagcctcctgggggagccatattgcttccaggtaacgtgggcaggtgggagccgctgtttctcttgtcgctcgagcgctgagagagaccgttggattgaggaccttcgtcggcagttccagcctagccaggacaatgtggaacgacaagagacctggctgacagtgtgggtgcacgaagccaaagggcttccccgagcagctgcacccggagtgcgtgcggagctgtggttggacggcgcgctactggcgcgcactgcccctcgggcgggccctgaccaactcttctgggccgaacgcttccacttcgaggcgttgccacctgcccgtcgcctgtcgctgcggctgcgcggagcaggcccggcaggggcaaccgtgggcagggtggtactagaactggacgaggtgagcatcccccgcgcgcctgccgcaggcctggagcgctggttccccgtgctcggggctccggcgggtgcggtgctacgggcgcggatcagggtacgatgtctgcgcgtgctgccgtcggagcgctataaggagttagcggagttcctcaccttccactacgcgcgcctgtgcatggcgctggagcccgcgctgtctgctcaggccaaggaggagctggcagcagccatggtgcgcgtgctacgagccactggccgagcgcaggcattggtgacagacctaggaaccgcagagctggagcgctgtggaggccgtgaagcgctgctattccgagaaaataccttagccacaaaggccattgatgaatacatgaaactggtggcacaggagtacctccaggagaccctgggccaggttgtgcggagtctctgtgcctccaccgaggactgtgaagtggaccccagcaagtgcccaacaccggagctgccaaaatgccaagctagactgcgaagcagttgtgaggaggtttttgaaaacatcatccactcttacaactatttcccagcagagctgggcaccgtgttctcaaattggcgggaagcatgcaaagcacgaggctctgaggcactgggcccccggctggtgtgtgcttctctcttcctaaggctcctatgccccgccatcttggcacctagcctctttggcctggcaccagagcaccccgccccaggcccagccagaactcttacactcatcgccaaggtcatccagaatcttgccaactgtgctccgtttggtgagaaggaagcctacatggtctttatgaatagcttcctggaagatcatggaccggccatgcgacacttcctggatcaggtagctatggtggacacagataccacacccagtggctaccagggaagtggagacctggccctccagttggcagttcttcatgtccagctctgcacaatctttgctgaacttgaccagaaaactcgagacagcttggaaccactacccaccatccttcaagccattgaggagggtcggcctgtcccagtgtctgtaccaatgcgtcttcccctgaacactgctcatgtccaatccagcttctcttcaggggagaaacccggcttcctggcaccccgagacctccccaagcacactcctctcatttccaagagccagtctttgcgcagctttcaaggggcaggaagctgggcccgtcggcggccagatggggagcggccccagcggcggccgcggccagtgctgcgcacacagagcgtccctgccagacgccctacccaccatcgccctgctgcgggttccaagcctcgacccaaaggctctctacgcactggtcctgcgacttccggacgggcctgggctaggacttccacctctctacctcggaagccatcggtgccttggcagcgccaactggaccagcccggggaccgataccaaactccgggaacgcaccgaccagtgggcaagctagcagagatacaatgcgaggtagctgcactccgcgaggaacagaaagccctgtcccatctggtggagtcgctgagtacccacatccaggccttgacggagcagcaagagcagctccgctgtcagctgcaggatctggactccagactgggagctgggatctcaaagttggattctaagggtggtctcccaagcaacggtagcctcgggctgaaaagtctggagcaccgcatgactgagatggaatgttctcagaaccagctgagggataccctccaaagcctacagcttctttcaaaaactccaggatctcggagccagcccccgcctctcaaagcaccatgtgtcaatggagctgatctgtcgatgggcacctgagtatttcaccccactccatacagtctggaagccaggagagccactacagaggattttctgactacctcagtccttcatggcccttagtaggggacagagtgggaggtgtcaatcactctggtaactgtgaggttgcccagtaaatctccatttcagaaaatcactggtttctctgcccctacaaagattaatgcaagagcatacccagttctctactcagctcccccaaattcttacctaatttgaagtctcccgaagatgaaaatgattagcaaaattgtcctcactattggtgtgatctaaggtcatcactctaaaagactccattctctcttctgtatctaaaaattctctgcatagttaaaggtattcaataaaaggtatttatcattgttgtgggaa
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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