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2024-11-01 08:23:59, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       NM_001134562            3502 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RAS protein activator like 3 (Rasal3), transcript
            variant 2, mRNA.
ACCESSION   NM_001134562 XM_001077947 XM_234839
VERSION     NM_001134562.3
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3502)
  AUTHORS   Saito,S., Kawamura,T., Higuchi,M., Kobayashi,T.,
            Yoshita-Takahashi,M., Yamazaki,M., Abe,M., Sakimura,K., Kanda,Y.,
            Kawamura,H., Jiang,S., Naito,M., Yoshizaki,T., Takahashi,M. and
            Fujii,M.
  TITLE     RASAL3, a novel hematopoietic RasGAP protein, regulates the number
            and functions of NKT cells
  JOURNAL   Eur J Immunol 45 (5), 1512-1523 (2015)
   PUBMED   25652366
REFERENCE   2  (bases 1 to 3502)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 3502)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Dec 15, 2022 this sequence version replaced NM_001134562.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.27401.1,
                                           SRR26643284.9762.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                JAXUCZ010000007.1  12061845-12061883   c
            40-368              JAXUCZ010000007.1  12061383-12061711   c
            369-508             JAXUCZ010000007.1  12057942-12058081   c
            509-587             JAXUCZ010000007.1  12057737-12057815   c
            588-649             JAXUCZ010000007.1  12057581-12057642   c
            650-720             JAXUCZ010000007.1  12054461-12054531   c
            721-847             JAXUCZ010000007.1  12053947-12054073   c
            848-946             JAXUCZ010000007.1  12053766-12053864   c
            947-1483            JAXUCZ010000007.1  12052826-12053362   c
            1484-1628           JAXUCZ010000007.1  12052238-12052382   c
            1629-1773           JAXUCZ010000007.1  12051463-12051607   c
            1774-2010           JAXUCZ010000007.1  12050446-12050682   c
            2011-2212           JAXUCZ010000007.1  12050148-12050349   c
            2213-2331           JAXUCZ010000007.1  12049938-12050056   c
            2332-2722           JAXUCZ010000007.1  12048793-12049183   c
            2723-2880           JAXUCZ010000007.1  12048438-12048595   c
            2881-2944           JAXUCZ010000007.1  12047748-12047811   c
            2945-3502           JAXUCZ010000007.1  12047090-12047647   c
FEATURES             Location/Qualifiers
     source          1..3502
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..3502
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="RAS protein activator like 3"
                     /db_xref="GeneID:314596"
                     /db_xref="RGD:1309019"
     exon            1..39
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            40..368
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..3100
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="RAS protein activator like-3 isoform 2"
                     /protein_id="NP_001128034.1"
                     /db_xref="GeneID:314596"
                     /db_xref="RGD:1309019"
                     /translation="
MDPPLQNEDSQTQPSPLTSYRWHTGGRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNRLRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFALLEGRLVMLGEEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLSELDLGVERDVRVWPLHPSLLGEPYCFQVTWAGGSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAAPGVRAELWLDGALLARTAPRAGPDQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELERCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDPSKCPTPELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTRDSLEPLPTILQAIEEGRPVPVSVPMRLPLNTAHVQSSFSSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWARRRPDGERPQRRPRPVLRTQSVPARRPTHHRPAAGSKPRPKGSLRTGPATSGRAWARTSTSLPRKPSVPWQRQLDQPGDRYQTPGTHRPVGKLAEIQCEVAALREEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLGLKSLEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVNGADLSMGT"
     misc_feature    581..1021
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="Pleckstrin homology-like domain; Region: PH-like;
                     cl17171"
                     /db_xref="CDD:473070"
     misc_feature    938..1336
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="C2 domain; Region: C2; cl14603"
                     /db_xref="CDD:472691"
     misc_feature    1310..2281
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="Ras-GTPase Activating Domain of DAB2IP and similar
                     proteins; Region: RasGAP_DAB2IP; cd05136"
                     /db_xref="CDD:213338"
     misc_feature    order(1427..1429,1538..1540,1544..1546,1550..1555,
                     1559..1561,1568..1570,1580..1582,1856..1858,1880..1885,
                     1892..1897,1904..1906,1967..1969,1976..1981,1988..1990,
                     2000..2002,2006..2008,2021..2026)
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="putative RAS interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:213338"
     exon            369..508
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            509..587
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            588..649
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            650..720
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            721..847
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            848..946
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1483
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1628
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1773
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..2010
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2011..2212
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2331
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2332..2722
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2723..2880
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2881..2944
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2945..3502
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
acagacggctgctggttctggactggccaggaaatcaagcagagactccgccatggacccaccgctgcagaatgaagattcccaaacgcagccctcgccgctgacgtcctatcgttggcacactggaggcagaggggagaagattgctggagggttccgctggggccgcttcgcaggctggggaagggccctgagccatcaggagcccatggtgagcagccagccagcccctagatctctgtttcgtcgggtcctctctgcacctcctaaggagtcacgacccaatcgcctccggttttccaagagcctgtgggggaggcacaagaacgtggtaccgctggaacccaagctaaatccgaaggccccagagccagagctggagttggagggagccccagacctgcgcgctgcacatatccctgagcctcccgcccctgacatgcctgtttggaacattgatggctttgccctgctcgaaggaagactggtgatgctcggtgaggaggagggtcctcgccaaatccgaatgggaagtgccagctcggaaagcagcatgcaggcagccttggggaacctcaaagacccagttcggactcctgggaaaattgagccggaagctactggttccaaccaggtccacaatgttcggaagttactcaagaggctgaaggagaagaaaagggccaagtcggaactgggagcccacactcctcgagatggaccctccagtgctcttggttccagagaatcgctggccacactctctgagctggacctaggcgttgagagggatgtgagagtctggccgctgcatcctagcctcctgggggagccatattgcttccaggtaacgtgggcaggtgggagccgctgtttctcttgtcgctcgagcgctgagagagaccgttggattgaggaccttcgtcggcagttccagcctagccaggacaatgtggaacgacaagagacctggctgacagtgtgggtgcacgaagccaaagggcttccccgagcagctgcacccggagtgcgtgcggagctgtggttggacggcgcgctactggcgcgcactgcccctcgggcgggccctgaccaactcttctgggccgaacgcttccacttcgaggcgttgccacctgcccgtcgcctgtcgctgcggctgcgcggagcaggcccggcaggggcaaccgtgggcagggtggtactagaactggacgaggtgagcatcccccgcgcgcctgccgcaggcctggagcgctggttccccgtgctcggggctccggcgggtgcggtgctacgggcgcggatcagggtacgatgtctgcgcgtgctgccgtcggagcgctataaggagttagcggagttcctcaccttccactacgcgcgcctgtgcatggcgctggagcccgcgctgtctgctcaggccaaggaggagctggcagcagccatggtgcgcgtgctacgagccactggccgagcgcaggcattggtgacagacctaggaaccgcagagctggagcgctgtggaggccgtgaagcgctgctattccgagaaaataccttagccacaaaggccattgatgaatacatgaaactggtggcacaggagtacctccaggagaccctgggccaggttgtgcggagtctctgtgcctccaccgaggactgtgaagtggaccccagcaagtgcccaacaccggagctgccaaaatgccaagctagactgcgaagcagttgtgaggaggtttttgaaaacatcatccactcttacaactatttcccagcagagctgggcaccgtgttctcaaattggcgggaagcatgcaaagcacgaggctctgaggcactgggcccccggctggtgtgtgcttctctcttcctaaggctcctatgccccgccatcttggcacctagcctctttggcctggcaccagagcaccccgccccaggcccagccagaactcttacactcatcgccaaggtcatccagaatcttgccaactgtgctccgtttggtgagaaggaagcctacatggtctttatgaatagcttcctggaagatcatggaccggccatgcgacacttcctggatcaggtagctatggtggacacagataccacacccagtggctaccagggaagtggagacctggccctccagttggcagttcttcatgtccagctctgcacaatctttgctgaacttgaccagaaaactcgagacagcttggaaccactacccaccatccttcaagccattgaggagggtcggcctgtcccagtgtctgtaccaatgcgtcttcccctgaacactgctcatgtccaatccagcttctcttcaggggagaaacccggcttcctggcaccccgagacctccccaagcacactcctctcatttccaagagccagtctttgcgcagctttcaaggggcaggaagctgggcccgtcggcggccagatggggagcggccccagcggcggccgcggccagtgctgcgcacacagagcgtccctgccagacgccctacccaccatcgccctgctgcgggttccaagcctcgacccaaaggctctctacgcactggtcctgcgacttccggacgggcctgggctaggacttccacctctctacctcggaagccatcggtgccttggcagcgccaactggaccagcccggggaccgataccaaactccgggaacgcaccgaccagtgggcaagctagcagagatacaatgcgaggtagctgcactccgcgaggaacagaaagccctgtcccatctggtggagtcgctgagtacccacatccaggccttgacggagcagcaagagcagctccgctgtcagctgcaggatctggactccagactgggagctgggatctcaaagttggattctaagggtggtctcccaagcaacggtagcctcgggctgaaaagtctggagcaccgcatgactgagatggaatgttctcagaaccagctgagggataccctccaaagcctacagcttctttcaaaaactccaggatctcggagccagcccccgcctctcaaagcaccatgtgtcaatggagctgatctgtcgatgggcacctgagtatttcaccccactccatacagtctggaagccaggagagccactacagaggattttctgactacctcagtccttcatggcccttagtaggggacagagtgggaggtgtcaatcactctggtaactgtgaggttgcccagtaaatctccatttcagaaaatcactggtttctctgcccctacaaagattaatgcaagagcatacccagttctctactcagctcccccaaattcttacctaatttgaagtctcccgaagatgaaaatgattagcaaaattgtcctcactattggtgtgatctaaggtcatcactctaaaagactccattctctcttctgtatctaaaaattctctgcatagttaaaggtattcaataaaaggtatttatcattgttgtgggaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]