LOCUS       NM_001434628            6528 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Rattus norvegicus GRIP and coiled-coil domain containing 2 (Gcc2),
            transcript variant 1, mRNA.
ACCESSION   NM_001434628 XM_006256375
VERSION     NM_001434628.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6528)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 6528)
  AUTHORS   Burguete,A.S., Fenn,T.D., Brunger,A.T. and Pfeffer,S.R.
  TITLE     Rab and Arl GTPase family members cooperate in the localization of
            the golgin GCC185
  JOURNAL   Cell 132 (2), 286-298 (2008)
   PUBMED   18243103
REFERENCE   3  (bases 1 to 6528)
  AUTHORS   Efimov,A., Kharitonov,A., Efimova,N., Loncarek,J., Miller,P.M.,
            Andreyeva,N., Gleeson,P., Galjart,N., Maia,A.R., McLeod,I.X.,
            Yates,J.R. 3rd, Maiato,H., Khodjakov,A., Akhmanova,A. and
            Kaverina,I.
  TITLE     Asymmetric CLASP-dependent nucleation of noncentrosomal
            microtubules at the trans-Golgi network
  JOURNAL   Dev Cell 12 (6), 917-930 (2007)
   PUBMED   17543864
REFERENCE   4  (bases 1 to 6528)
  AUTHORS   Derby,M.C., Lieu,Z.Z., Brown,D., Stow,J.L., Goud,B. and
            Gleeson,P.A.
  TITLE     The trans-Golgi network golgin, GCC185, is required for
            endosome-to-Golgi transport and maintenance of Golgi structure
  JOURNAL   Traffic 8 (6), 758-773 (2007)
   PUBMED   17488291
REFERENCE   5  (bases 1 to 6528)
  AUTHORS   Reddy,J.V., Burguete,A.S., Sridevi,K., Ganley,I.G., Nottingham,R.M.
            and Pfeffer,S.R.
  TITLE     A functional role for the GCC185 golgin in mannose 6-phosphate
            receptor recycling
  JOURNAL   Mol Biol Cell 17 (10), 4353-4363 (2006)
   PUBMED   16885419
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Nov 15, 2024 this sequence version replaced XM_006256375.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1696385.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                JAXUCZ010000020.1  26790585-26790654
            71-124              JAXUCZ010000020.1  26790905-26790958
            125-209             JAXUCZ010000020.1  26791877-26791961
            210-277             JAXUCZ010000020.1  26793152-26793219
            278-382             JAXUCZ010000020.1  26799262-26799366
            383-2824            JAXUCZ010000020.1  26800507-26802948
            2825-2897           JAXUCZ010000020.1  26803568-26803640
            2898-2998           JAXUCZ010000020.1  26805861-26805961
            2999-3097           JAXUCZ010000020.1  26806053-26806151
            3098-3217           JAXUCZ010000020.1  26807663-26807782
            3218-3382           JAXUCZ010000020.1  26809409-26809573
            3383-3487           JAXUCZ010000020.1  26809850-26809954
            3488-3650           JAXUCZ010000020.1  26810725-26810887
            3651-3751           JAXUCZ010000020.1  26815784-26815884
            3752-3829           JAXUCZ010000020.1  26815971-26816048
            3830-3967           JAXUCZ010000020.1  26816855-26816992
            3968-4089           JAXUCZ010000020.1  26818520-26818641
            4090-4266           JAXUCZ010000020.1  26820155-26820331
            4267-4484           JAXUCZ010000020.1  26822305-26822522
            4485-4679           JAXUCZ010000020.1  26824180-26824374
            4680-4831           JAXUCZ010000020.1  26825542-26825693
            4832-5033           JAXUCZ010000020.1  26827814-26828015
            5034-6528           JAXUCZ010000020.1  26835233-26836727
FEATURES             Location/Qualifiers
     source          1..6528
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..6528
                     /gene="Gcc2"
                     /note="GRIP and coiled-coil domain containing 2"
                     /db_xref="GeneID:309798"
                     /db_xref="RGD:1305732"
     exon            1..70
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..5104
                     /gene="Gcc2"
                     /note="isoform 1 is encoded by transcript variant 1; 185
                     kDa Golgi coiled-coil protein; LIM and senescent cell
                     antigen-like domains 1; GRIP and coiled-coil
                     domain-containing protein 2"
                     /codon_start=1
                     /product="GRIP and coiled-coil domain-containing protein 2
                     isoform 1"
                     /protein_id="NP_001421557.1"
                     /db_xref="GeneID:309798"
                     /db_xref="RGD:1305732"
                     /translation="

MEVTDSAQDAVTAAPSGTPKSKLETLPREDLIKFAKKQMMLLQKAKARCTELDKEVEELKSKPVDGGTDDMIKVLTERLDALLLEKAETEQQCLCLKKENIKMKQEVEDSVTKLEETQKEFEQSHRNYVREMESVKNELIAVHSEHSKEKAALQRDLEGAVHRQAELLEQLKSQSDSEDNVKKLQEEIQNITAAFEEQTSCLQKQLEATSDEKQQEIIHLQKVIEDNAQHYQKDINTFQEEIVQLRATHKEEVNELMSQMETLAKEHEAAVNKLKENRVTLCETSETIPENYQCESESLNEDTSDASQENQKCSVALQEDPFAEHTVYDKVRQLEDSLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQSYVVEKLKYEREDLNRQLCCTVEQHNKEIQRLQEHHQKEISELSETFMSGSEKEKLALMFEIQGLKEQCENLQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQQASDVHELQQKLRTAFNEKDALLETINRLQGENEKLLSQELVSELESTMKNLKADNSMYLASLGQKDTLLQELEAKISSLAEEKDDFISKIKTSREEIDDLHQKWEREQKLSVELREAAEQAAQHNSELRQRVSELTGKLDEILREKSQNDQNIMVQMKTMTEDQEALSSKIKSLYEENNRLHSEKVQLSRDLEALQSQQDFAYKEHVAEFEKKLQLMVEERDDLNKLLENEQLQKSFVKTQLYEFLKQMRPSILEDNEEEDVVTVLKAVGESLVTVKEEKHNLVFEYDARVLELERRIKCLQEESVVQCEELRALVRDSEQEKILLRKELDEVTSTKEALQCDILEMKNTNEKTSLENQTLSTRVEELSRSLHSKNEVHNEKDLVIEHENLRLSLEQRESELQDVRAELMLLKDSLEKSPSVKNDQLSLVKELEEKIESLEKESKDKDEKISKIKLVAVRAKKELDSNRKEAQTLRDELESVQSEKDRLSASMKEFIQGAESYKNLLLEYDKQSEQLDVEKERANNFEHHIEDLTKQLRDSTCQYEKLTSDNEDLLARIETLQANARLLEAQILEVQRAKGVVEKELEAEKLQKEQKIKEHVSTTNELEELQLQFQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSKIEDLEQEMKIQKQKQETLQEEMTSLQSSVQHYEEKNAQIKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKIQLAEMTSEKHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRTAKAEQAAVTSEFENYKVRVHNVLKQQKNKSVSQAETEGAKQEREHLEMLIDQLKIKLQDSQNSLQISVSEFQTLQSEHDTLLERHNRMLQETVTKEAELREKLCSAQSENTMLKSEHAQTMCQLTSQNEALRNSFRDQVRHLQDEHRKTVETLQHQLSKVETQLFQLKSEPPTKSPASSHQPSKSLRERRTTDLPLLDMHTVTREEGEGMETTDSESVSSAGTHIQSLEQLLSSPDSKLERLTEASLWHTEFTKEELAEKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLRFIFLKPGSERERLLPVIDTMLQLSPEEKGKLATVAQGEEESASRSSGWASYLHSWSGLR"

     exon            71..124
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            125..209
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            210..277
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            278..382
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            383..2824
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2825..2897
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2898..2998
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2999..3097
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3098..3217
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3218..3382
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3383..3487
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3488..3650
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3651..3751
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3752..3829
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3830..3967
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3968..4089
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4090..4266
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4267..4484
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4485..4679
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4680..4831
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4832..5033
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            5034..6528
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agaggcggagtacctaggacgcctgaaaaggccgaggtggccgcgggtcgctgccacgatggaggtaacggattctgctcaagatgctgtgactgcagcaccctccgggaccccgaaatccaagctagaaacattgcccagagaagatctcatcaagtttgccaagaagcagatgatgctcctacagaaagccaaagcaaggtgtacagaattagacaaagaagttgaagagctcaaatcaaaacctgttgacggaggaactgatgatatgattaaggtgctaactgaacgcttggatgctcttcttctggaaaaagcagagactgaacaacagtgtctgtgtctcaaaaaagaaaatattaaaatgaagcaagaggttgaggattctgtaactaaactggaagagacacaaaaagagtttgaacaatcacatagaaactacgtaagagaaatggaaagtgttaaaaatgaactgatagcagtacactcagagcacagcaaagaaaaggctgccttacaaagagacctggagggagcagtccataggcaagcagagctgttagaacagctcaagtctcagagcgactctgaagataatgttaaaaaactacaggaagagattcagaacattacagcagcatttgaggaacaaacgtcatgtctacaaaagcaattagaagctaccagtgatgaaaaacagcaagagattattcatctccagaaagtcattgaggacaacgctcagcactaccaaaaagatattaatactttccaagaagagattgtgcagctgagagctacacacaaagaagaagttaatgagctgatgtctcaaatggaaacattagctaaagaacatgaggcagcagtaaataagctaaaagagaacagagtgacactgtgtgagacaagtgagaccattccagagaattaccaatgtgaatcagaaagcttaaatgaagacacctcagatgcaagccaggagaatcaaaaatgctctgtggccttacaggaagatccttttgcagaacatacagtgtatgataaagtcagacaattggaagattcattaaaagaactggaatctcaacatagtatcttaaaagatgaagtgacttatatgaataatctcaagttaaaacttgaaatggatgcccagcatataaaggatgagtttttccatgaaagagaagacttggagtttaaaattaatgaactgttgctggccaaagaagaacagagctacgtagtagaaaaattaaaatatgagcgagaagatttaaataggcagctttgctgtactgtggaacaacataacaaagaaatacagcgtcttcaggagcaccatcagaaagaaatctctgaactaagtgagacatttatgtcaggttcagaaaaagaaaagttagcattaatgtttgaaatacagggacttaaggaacagtgtgaaaatctacaacatgaaaagcaagaggtagttctaaattatgagagtttacgagagatgatggaaattttacaaacggaacttggagaatctgctggaaaaataagtcaagagtttgaaacaatgaagcaacagcaagcatctgatgttcatgagcttcagcagaagctaagaactgcttttaacgaaaaagacgctcttcttgaaactataaatcgcctacaaggagaaaatgaaaaattattatcacaagaattggtatcagaactcgaaagtaccatgaagaaccttaaggcagataatagcatgtacttagccagccttggtcaaaaagataccctgttacaagaattagaagcaaagataagttctcttgctgaagaaaaagatgattttataagtaaaatcaaaacttcccgtgaagagatagatgatctccatcagaaatgggaaagggaacagaaactgtctgtagaactcagggaagcagcagagcaagccgcccagcacaacagtgaactgagacaaagagtaagtgaattaacaggaaaactagatgaaatattaagagaaaagagtcaaaatgaccaaaacattatggttcaaatgaaaaccatgacagaagaccaagaagcattgtcatctaaaatcaagtctctttatgaggaaaacaatagactgcattctgaaaaggtccagttgagtagagatttagaagctcttcagtctcaacaagattttgcctataaagagcatgttgctgaattcgaaaagaaactccagttaatggttgaagaacgagatgatttaaataaactgcttgaaaatgagcaacttcagaagtcatttgtcaaaactcagttgtacgagtttcttaagcaaatgaggccaagcattttagaagataatgaagaggaagatgttgtcacagttctaaaagctgtgggtgaatccttagtgacagtaaaggaagaaaagcataacttagtctttgaatatgatgcgagagtattagaattagaaaggaggattaagtgccttcaagaggagagtgtagttcagtgtgaagaactaagggctttagtaagagactctgaacaagagaaaattctcctaagaaaagaattagatgaagtcacatcaacaaaagaggccctgcagtgtgatattctagaaatgaagaatactaatgaaaaaacaagccttgaaaatcagactctttcaactcgggttgaagaattatcgcggtcattacacagcaaaaatgaagtccataatgaaaaggatcttgtcatagaacatgaaaacctgaggctatcgcttgagcagagggagtctgagctacaagatgtgagagcagaattgatgctgctgaaggattccttagagaaatcgccttctgtaaaaaatgatcaactttcattggtaaaagagctggaagaaaaaatagaaagtctggaaaaagaatccaaagacaaggatgagaaaatcagtaagataaaactagtcgctgtgagagcaaagaaagaactagattctaacaggaaagaggcccagacactacgggacgaactcgagtccgtacagtcagaaaaggaccgcttatctgcttctatgaaggagtttatccaaggagcagaaagctataagaatcttctgttagaatatgacaagcagtcagaacagctggatgtggaaaaagaacgtgctaataattttgaacatcacatagaagaccttaccaaacaattaagagattcgacttgccagtatgaaaaactaacttccgacaatgaggatctcctggctcgaattgagaccctgcaggctaatgccaggttattagaagcacagatcttagaggtccagagagccaaaggagtagtagaaaaagaactggaagctgaaaaacttcagaaagagcagaaaattaaggaacatgtcagtactacaaatgagcttgaagaacttcaactccaatttcaaaaggaaaagaagcagcttcagaaaacgatgcaagaattagaactggttaaaaaggatgcccaacagaccacgttgatgaatatggaaatagcagattacgaacgtttgatgaaagaattaaatcaaaagttaacaaataaaaacagtaagatagaagatttggagcaagaaatgaaaattcagaaacagaaacaagaaaccctacaagaagaaatgacttccctgcagtcttcagtacagcactacgaagaaaagaacgcccaaatcaagcagctgcttgtgaaaaccaaaaaggaactggcagatgcaaagcaagcagaaactgatcacttactactccaggcgtctttaaagggcgagctggaagcaagccagcagcaagtagaagtctataaaattcagctagctgagatgacatctgagaaacacaaaatccatgagcacctgaagacttctgcggaacagcaccagcgcacactaagtgcataccagcagagggtggtggccctgcaggaagagagccgcactgccaaggcagagcaagctgctgtcacctctgaatttgagaactacaaagtccgggttcataacgttctaaaacaacagaaaaataaatctgtgtctcaggctgaaactgagggagctaaacaagaaagggaacacctggaaatgctgattgaccaactgaaaatcaagttacaggacagccaaaacagcttacaaatcagtgtgtcagagttccagacactgcagtctgagcatgacactctgctagagaggcacaaccggatgctgcaggaaactgtgaccaaagaggcggaacttcgggaaaagttatgttcagctcaatctgagaacaccatgttgaagtctgaacacgcccagacaatgtgtcagctgacatcccagaatgaggccctccgtaacagcttccgagaccaagttcgacacttgcaggatgagcacagaaagacagtggagaccttgcagcaccagctctccaaggtggaaactcagctcttccagctcaagagtgagccacccacaaaaagccctgcttcttcccatcaaccttcaaaaagcctccgagaaagacggaccacagacctcccccttctggacatgcacactgtgacccgagaggagggggaagggatggagacaactgacagtgagtctgtgtcttcggccggcacacacattcagtccttggagcagctccttagctctcctgacagcaagcttgaacgtcttacagaggcctccttatggcatacagaatttaccaaagaagaattggctgagaagctcagttccaccacgaagagtgcagatcacttaaatggcctgcttcgggagacagaggctaccaacgccatccttatggagcaaattaagcttctcaaaagtgaaataagaagactggaaagaaaccaagagcgggagaagtctgtggctaacctggagtacttgaagaatgtcctactgcggttcattttcctgaagccgggtagtgaaagagagaggcttcttcctgtgatagacacgatgctgcagctcagccctgaagaaaagggaaagcttgccacagttgctcaaggtgaggaagaaagtgcctctcgttcctctggatgggcatcctaccttcatagctggtctggactgcgataggttgacagaaagaagattctttagtgatgcaacagaactcctttggaaaagctgggtatcatttgatcatgaagtgtgcatctctgttcacatcccctgatgattgtacatatgtatagcccatgtatatagaatctcatcttgtagtaaaaggacatcagcttgaagtagtggtaccaattgttcatggtcctctaactcagcatgtggcctcatggtctctgtgatctccacccacagaggaaacggttcattcctgcactctggaaccccaggagacactcatttctaagtagtattgtgaattttgatattgaactaaattttggtaccaaaccaactggggaatttaatcttttaaaataatgtttcaagattgaggaaatgctttattgataaggttgacatgtttattaaaagattatgaagtaaatatgctatggtttaattatgaggctaacttaaattgcaattcagtcagttactttaaaataaacctccctcccatttgtaattttcaaaattggccctagtcctggtaatgtgacactgacagaataggtgggctccacctcagctgatgtgttctgtggtgtctccaggcttgtttgctgccactcataagccatgagtctcttttgagaattccctacatctcaaaacagtgactgtcttactcagcattaaatctacatgtgaacctggtgcttccagtattgttcaagtattcttatttcctaagcaggaccccagagggctcagaccctctattggtgaacaagcctagctgggggagtgtctctgtccttatgtctctggaaatactatattgactagattaaaattgtgctcttaaatcagatttgggggttatattttaatatgtaatttgttaatgaatagtgctgtctggagtcttaagcttacgtttattctccagttgtcagtctcagcttgaaactgtcctttagtcactatgaatattggtttccaacctggtttgactgaaatttactgctgacatgttgagtttgttctcttaaagctgtttgactctcagtgttcgctctacctgtgttagaacagacctagcaagtgagtgtgctgattcaaacacatctctctcagctgactctttaaggtaaggttttctacctttataaactgtgaatgtgagtatgcccagcggaatcccatgtaatttcagtactatttaaataaactccatgttttctttgggcctaatatgccttttgaagtctgtataaacttgttttcaaatctaatctgttcatatgaatataataaaaataccttttgcatggtaaaaattactttgattacaaaagatatatatatgctttttgtgaccagcaataagaaactgtaatgactgatatttctattaaatgcacttaactata

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