LOCUS       NM_001399007            1109 bp    mRNA    linear   ROD 25-FEB-2022
DEFINITION  Rattus norvegicus mitochondrial ribosomal protein L15 (Mrpl15),
            transcript variant 3, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001399007
VERSION     NM_001399007.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1109)
  AUTHORS   Brown A, Rathore S, Kimanius D, Aibara S, Bai XC, Rorbach J, Amunts
            A and Ramakrishnan V.
  TITLE     Structures of the human mitochondrial ribosome in native states of
            assembly
  JOURNAL   Nat Struct Mol Biol 24 (10), 866-869 (2017)
   PUBMED   28892042
REFERENCE   2  (bases 1 to 1109)
  AUTHORS   Brown A, Amunts A, Bai XC, Sugimoto Y, Edwards PC, Murshudov G,
            Scheres SHW and Ramakrishnan V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   3  (bases 1 to 1109)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1109)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1109)
  AUTHORS   Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S
            and Russo T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   6  (bases 1 to 1109)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000160.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR8487226.14856.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-173               JACYVU010000160.1  2738062-2738234
            174-328             JACYVU010000160.1  2739543-2739697
            329-488             JACYVU010000160.1  2740406-2740565
            489-612             JACYVU010000160.1  2745245-2745368
            613-1109            JACYVU010000160.1  2745984-2746480
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q12"
     gene            1..1109
                     /gene="Mrpl15"
                     /note="mitochondrial ribosomal protein L15"
                     /db_xref="GeneID:297799"
                     /db_xref="RGD:1304796"
     exon            1..173
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..950
                     /gene="Mrpl15"
                     /EC_number="3.6.5.3"
                     /note="isoform 3 is encoded by transcript variant 3; 39S
                     ribosomal protein L15, mitochondrial"
                     /codon_start=1
                     /product="39S ribosomal protein L15, mitochondrial isoform
                     3"
                     /protein_id="NP_001385936.1"
                     /db_xref="GeneID:297799"
                     /db_xref="RGD:1304796"
                     /translation="

MAGMAFGRGTSLDLLRSLPRVSLANLKPSLNSRKRERRPRDRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHRHQYQPLSLRRLQYLIDLGRVDPTQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFQAKVNIEVQMASELAIAAIEKNGGVVTTAFYDPRSLEILCKPVPFFLRGQPIPKRMLPPEALVPYYTDAKNRGYLADPAKFPEARLELAMKYGYVLPDVTKDELFRMLSTRKDPRQIFFGLAPGWIVNMADKKILKPTDENLLKYYSS"

     misc_feature    222..584
                     /gene="Mrpl15"
                     /note="Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A;
                     Region: Ribosomal_L27A; pfam00828"
                     /db_xref="CDD:425890"
     exon            174..328
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            329..488
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            489..612
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            613..1109
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggggcgtggccgtaaagcaatgcggagccttcgccgccttctgggcgcccttgaaaggaccgtgggccatggctggcatggcgtttggccgcgggaccagtctggaccttctgcggtccttgccgagagtgagcctggccaatctgaagcccagtcttaactccagaaaacgggaaagacgtccaagagatcggagaagaggtaggaagtgtggcagaggccataaaggagaaagacagagaggaacccggcccaggctgggctttgagggagggcagactccattttacatccgaatcccaaaatatggatttaatgaaggacataggcaccagtatcagcctctgagtctcaggagactacagtatctcattgatttaggtcgagttgatccaactcaacctattgacttaacgcagcttgtgaatgggagaggtgtgaccatccagccacttaaaagggattatggggtccagctggttgaagagggtgctgatacttttcaagcaaaagttaatattgaggtgcagatggcttcagaattagccattgctgcaattgaaaaaaatggtggtgttgttactacagccttctatgacccaagaagtctagaaattctgtgcaagcctgttccattctttctgcgcggacaacccattccaaagagaatgcttccacccgaggcgctggtgccctattataccgatgcgaaaaaccgggggtacctggccgaccctgccaagtttcctgaagcaagactggaacttgccatgaagtatggctatgtccttcctgatgtcacgaaagacgaactcttcagaatgctcagcacccgcaaggatccaaggcagattttctttggtcttgctcctggctggatagtgaatatggcagataagaaaattctaaaacctacagatgagaatcttctcaagtattacagctcctgaactgccttcagtaaatcagacatgtgagccaggggggctgaacacgggctcgtgtgggccttaaagccgaggggctggtaccgcctgcactggtcaggtttcttgttctttttccatctgaaattaaataacaggcagcaaaagctgcatcggaactga

//