LOCUS       NM_001108155            3326 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus kinesin family member 23 (Kif23), mRNA.
ACCESSION   NM_001108155 XM_001073723 XM_236313
VERSION     NM_001108155.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3326)
  AUTHORS   Kuo JC, Han X, Hsiao CT, Yates JR 3rd and Waterman CM.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   2  (bases 1 to 3326)
  AUTHORS   Chang YC, Chen YJ, Wu CH, Wu YC, Yen TC and Ouyang P.
  TITLE     Characterization of centrosomal proteins Cep55 and pericentrin in
            intercellular bridges of mouse testes
  JOURNAL   J Cell Biochem 109 (6), 1274-1285 (2010)
   PUBMED   20186884
REFERENCE   3  (bases 1 to 3326)
  AUTHORS   Kamijo K, Ohara N, Abe M, Uchimura T, Hosoya H, Lee JS and Miki T.
  TITLE     Dissecting the role of Rho-mediated signaling in contractile ring
            formation
  JOURNAL   Mol Biol Cell 17 (1), 43-55 (2006)
   PUBMED   16236794
REFERENCE   4  (bases 1 to 3326)
  AUTHORS   Yuce O, Piekny A and Glotzer M.
  TITLE     An ECT2-centralspindlin complex regulates the localization and
            function of RhoA
  JOURNAL   J Cell Biol 170 (4), 571-582 (2005)
   PUBMED   16103226
REFERENCE   5  (bases 1 to 3326)
  AUTHORS   Zhu C, Zhao J, Bibikova M, Leverson JD, Bossy-Wetzel E, Fan JB,
            Abraham RT and Jiang W.
  TITLE     Functional analysis of human microtubule-based motor proteins, the
            kinesins and dyneins, in mitosis/cytokinesis using RNA interference
  JOURNAL   Mol Biol Cell 16 (7), 3187-3199 (2005)
   PUBMED   15843429
REFERENCE   6  (bases 1 to 3326)
  AUTHORS   Tomas A, Futter C and Moss SE.
  TITLE     Annexin 11 is required for midbody formation and completion of the
            terminal phase of cytokinesis
  JOURNAL   J Cell Biol 165 (6), 813-822 (2004)
   PUBMED   15197175
REFERENCE   7  (bases 1 to 3326)
  AUTHORS   Mishima M, Kaitna S and Glotzer M.
  TITLE     Central spindle assembly and cytokinesis require a kinesin-like
            protein/RhoGAP complex with microtubule bundling activity
  JOURNAL   Dev Cell 2 (1), 41-54 (2002)
   PUBMED   11782313
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_236313.4, XM_001073723.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed/partial sample support SAMD00132261,
                              SAMD00132262 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3326
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..3326
                     /gene="Kif23"
                     /note="kinesin family member 23"
                     /db_xref="GeneID:315740"
                     /db_xref="RGD:1308596"
     exon            1..107
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    22..24
                     /gene="Kif23"
                     /note="upstream in-frame stop codon"
     CDS             97..2955
                     /gene="Kif23"
                     /codon_start=1
                     /product="kinesin-like protein KIF23"
                     /protein_id="NP_001101625.1"
                     /db_xref="GeneID:315740"
                     /db_xref="RGD:1308596"
                     /translation="

MKSAKAKMPRKPVIKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVVNSTTVQLHTPEGYRLNRNGDYKETQYSFKRVFGTHTTQKELFDVVASPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRFVFKSNDRNSMEIQCEVDALLERQKREAMPIPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYLYDLLEEVQFDPIKPKLPQSKMLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQMYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARPVDKAICGLTPGRRYRNLPRAGPVGDEPLTEEILQSFPPLPPCKLLDVNDEETLPRLMDALEKRHRLRQLMTEELNKQCVAFKALFKEFDNSLSNKENYIQEKLNEKEKVISGQKSEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQHQKLQREFSDKRRLEARLQGMVTETTMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPEKPERPSRDRDREKIIQRSVSPSPVPLSSNNIAQISNGQQLMSQPQLHRRSNSCSSISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKACMVSDRRRGMCWTEGREMVPTFSSEIGVQEDHCRRNTPIPVRHRRSRSAGSRWVDHKPASNVQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQESPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP"

     misc_feature    166..1398
                     /gene="Kif23"
                     /note="Kinesin motor domain, KIF23-like subgroup; Region:
                     KISc_KIF23_like; cd01368"
                     /db_xref="CDD:276819"
     misc_feature    order(193..195,430..432,439..441,445..456,1105..1107)
                     /gene="Kif23"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:276819"
     misc_feature    order(1261..1263,1270..1272,1279..1281)
                     /gene="Kif23"
                     /note="microtubule interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:276819"
     misc_feature    <1600..>2100
                     /gene="Kif23"
                     /note="DNA double-strand break repair ATPase Rad50;
                     Region: PRK03918"
                     /db_xref="CDD:235175"
     misc_feature    2482..2790
                     /gene="Kif23"
                     /note="Arf6-interacting domain of mitotic kinesin-like
                     protein 1; Region: MKLP1_Arf_bdg; pfam16540"
                     /db_xref="CDD:435410"
     exon            108..177
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            178..306
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            307..412
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            413..549
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            550..659
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            660..830
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            831..943
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1065
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1168
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1248
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1368
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1495
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1651
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1809
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1983
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2163
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2475
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2703
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2704..2786
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2787..2868
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2869..2939
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2940..3326
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gcggccgcagcctccacggcttagttcccgccagccctgctccggtcggagcccgacgtcccgcgcgcgcgtcaggacagcacggagactgcggtcatgaagtcggcgaaggctaagatgcccaggaaacctgtaataaaaaaaggatctcagacaaaccttaaagatccagtgggggtgtactgtagggtgcgcccactgagctttcctgaccaagagtgctgtgtggaagtggtcaatagtacaaccgtgcagctccacacccctgagggctatcgactcaacagaaatggagactacaaggagactcagtactcatttaagcgggtatttggcacgcacaccacccagaaggagctttttgatgttgtggctagtcccttggtagatgacctcattcatggcaagaatggtcttttatttacatatggtgtgacgggaagtggaaaaacctacacaatgacagggtctccagggtccggaggcctgcttcctcgttgtttgaatatgatctttaacagcatagggtcatttcaagcaaaacgtttcgtgtttaagtctaatgataggaacagtatggaaatacagtgtgaagtcgatgccttgttagaacggcagaaaagagaagccatgcccattccaaagaccccctctagcaagcgacaagcagatccagagtttgcagatatgataaatgtacaagaattctgcaaagcagaagaagttgatgaagacagtgtctatggagtgtttgtctcttacattgaaatctataataattacctatatgatctattggaagaagtgcagtttgatcccataaagcccaaactcccacaatctaaaatgctccgagaagataagaaccacaatatgtatgttgcaggatgtacagaagtagaagtgaagtctacggaggaggcgttcgaggttttctggagaggtcagaaaaagagacgtattgctaacacccatttgaatagagagtccagtcgttcacatagcgtgttcagcattaaacttgtccaggctcccctggatgctgatggagacaatgtcttacaggaaaaagagcaaattactataagccagctgtctttggtagatcttgctggaagtgaaagaactaaccgtactaaagcagaagggaacaggttacgtgaagctggaaacattaatcagtcattgatgacactaagaacatgcatggaagtcctgagagagaaccagatgtatggaaccaacaagatggttccatatcgagattcaaagctaacgcatctattcaagaactactttgatggggaggggaaggttcggatgatcgtgtgtgtgaatcctaaggctgaagactatgaagaaagcttgcaagtcatgagatttgctgaagtaacccaagaagtggaagtagcaagaccagtagacaaggcgatatgtggcctgacaccggggagacggtacagaaacctgcctcgggcgggcccagttggagatgaacctttgactgaagagattctacagagcttcccaccactgcccccatgcaagcttttggatgtcaatgatgaggagacccttccaagactgatggatgctttggagaaacgacatcgcttacgacaactgatgactgaggagcttaacaaacaatgtgtagctttcaaagccttattcaaagaatttgacaattctctatcaaataaagaaaactacattcaggaaaaactaaatgaaaaagaaaaagtgatctcaggacagaaatcagaaatagaacgactggagaagaaaaacaaaactttggagtacaagattgagattttggagaaaacaactacgatctatgaagaagataagcgcaatctgcagcaggagcttgaaagccagcatcagaagctccagcgggagttttctgacaagcgcagattagaagccaggttgcaaggcatggtgacagaaacgacgatgaagtggcagaaggaatgtgagcgtcgggtggcagccacccagctagagatgcagaacaaactctgggtcaaagatgaaaagctcaaacagctgaaggccattgtgactgaacccaaacctgagaagccagagagaccctcccgggaccgggaccgggagaaaatcattcagagatctgtctctccttcacctgtgcctctttctagtaacaatattgctcagatttccaacggccagcaactcatgagccagccccagcttcacagacgctctaactcttgcagcagcatttctgtagcttcctgtatttcggaatgggagcagaaactgtctccattcagcacccctgtcaatgtcacctctcttgcaaggcacaggcagcaggagccaggacaaagtaaagcgtgtatggtgtcagacagaaggcgagggatgtgctggactgaaggcagggagatggtccctacattcagcagtgagataggcgtacaagaggaccactgccgcaggaacacaccaattcctgtacgacacagaaggtcccgctctgcagggagcagatgggtagatcataagcctgcctctaatgtgcaaactgagacagtcatgcagccacatgtccctcatgccatcacagtgtctgttgcaaatgaaaaggcactagctaagtgtgagaagtacatgctgacccaccaggaactggcctctgatggggagattcagactaaagtaattaagggtgatgtttataagacgagaggaggtggacagtcggttcagtttactgatattgagactttaaaacaagaatcgccaactggtagtcgaaaacgaagatcgtccacactagcacctgcccaacccgatggtacagagtctgaatggaccgatgtagaaacaaggtgttctgttgctgttgaaatgagagcaggatctcagctgggacccggatatcagcaccacgcacaacccaagcgcaagaaaccttgaactgacaaccctggtgacagaaggaggttttttgctcgtgttggtgatttacccaaagccgcaccagatgcagtgtcttgagtcgtcttgcagaagaatgtgtctagatcacattgccttttttattgtgacttttcaactgttctgaatattttctaagattttataaaaaacaaacaaatgctgctattgattagctgcaaaaaaatgcactttagacatatttaacaattaagatttttcaaagtaaaaatggtgactggccaatggttaaaccattttagggaaggtatttagaattttgtatgtatatattcactctctgacctttatatatgccaaaacagctaaataaaaaagcactcagaggc

//