LOCUS       NM_001100890            2724 bp    mRNA    linear   ROD 09-OCT-2023
DEFINITION  Rattus norvegicus G-rich RNA sequence binding factor 1 (Grsf1),
            mRNA.
ACCESSION   NM_001100890 XM_001073361 XM_223327
VERSION     NM_001100890.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2724)
  AUTHORS   Wang J, Lu J, Zhu Y, Huang Q, Gu Q, Tian S, Ge J, Lin X and Sha W.
  TITLE     Guanine-rich RNA sequence binding factor 1 regulates neuronal
            ferroptosis after spinal cord injury in rats via the GPX4 signaling
            pathway
  JOURNAL   Brain Res 1818, 148497 (2023)
   PUBMED   37506966
  REMARK    GeneRIF: Guanine-rich RNA sequence binding factor 1 regulates
            neuronal ferroptosis after spinal cord injury in rats via the GPX4
            signaling pathway.
REFERENCE   2  (bases 1 to 2724)
  AUTHORS   Pietras Z, Wojcik MA, Borowski LS, Szewczyk M, Kulinski TM,
            Cysewski D, Stepien PP, Dziembowski A and Szczesny RJ.
  TITLE     Dedicated surveillance mechanism controls G-quadruplex forming
            non-coding RNAs in human mitochondria
  JOURNAL   Nat Commun 9 (1), 2558 (2018)
   PUBMED   29967381
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2724)
  AUTHORS   Antonicka H and Shoubridge EA.
  TITLE     Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA
            Processing and Ribosome Biogenesis
  JOURNAL   Cell Rep 10 (6), 920-932 (2015)
   PUBMED   25683715
REFERENCE   4  (bases 1 to 2724)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 2724)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 2724)
  AUTHORS   Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J.
  TITLE     Dissecting Wnt/beta-catenin signaling during gastrulation using RNA
            interference in mouse embryos
  JOURNAL   Development 132 (11), 2599-2609 (2005)
   PUBMED   15857914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK474968.1, FM050032.1, CK601425.1 and BC103654.1.
            
            On or before Dec 20, 2009 this sequence version replaced
            XM_223327.4, XM_001073361.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                CK474968.1         1-39
            40-586              FM050032.1         1-547
            587-1029            CK601425.1         3-445
            1030-2724           BC103654.1         1-1695
FEATURES             Location/Qualifiers
     source          1..2724
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..2724
                     /gene="Grsf1"
                     /note="G-rich RNA sequence binding factor 1"
                     /db_xref="GeneID:305256"
                     /db_xref="RGD:1310858"
     exon            1..372
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..1458
                     /gene="Grsf1"
                     /codon_start=1
                     /product="G-rich sequence factor 1"
                     /protein_id="NP_001094360.1"
                     /db_xref="GeneID:305256"
                     /db_xref="RGD:1310858"
                     /translation="

MAGTRWVLGALLRGCGCNCSSCRRTGAACLPFYSAAGTFPSGVSGRRRLLLLLGAAAAAASQTRGLQLGPAAAGRLAGPVPVRPSAAAAAAASYSALRAPLLPRSLAAAAGPARGYCQESKTTYLEDLPPLPEYELSPSKLGEEVDDVYLIRAQGLPWSCTVEDVLSFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKPTPALSDGVVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSHKGKKMVSSPTTKYITEPEVVFEEHEVNEDARPMTAFESEKEIELPKEMSDKLAEAVDFGAVPSLHFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFDTHEDAVAAMLKDRSHVQHRYIELFLNSCPKGK"

     misc_feature    460..696
                     /gene="Grsf1"
                     /note="RNA recognition motif 1 (RRM1) found in G-rich
                     sequence factor 1 (GRSF-1) and similar proteins; Region:
                     RRM1_GRSF1; cd12730"
                     /db_xref="CDD:410129"
     misc_feature    760..990
                     /gene="Grsf1"
                     /note="RNA recognition motif 2 (RRM2) found in G-rich
                     sequence factor 1 (GRSF-1) and similar proteins; Region:
                     RRM2_GRSF1; cd12505"
                     /db_xref="CDD:409928"
     misc_feature    1216..1440
                     /gene="Grsf1"
                     /note="RNA recognition motif 3 (RRM3) found in G-rich
                     sequence factor 1 (GRSF-1) and similar proteins; Region:
                     RRM3_GRSF1; cd12733"
                     /db_xref="CDD:410132"
     exon            373..529
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            530..685
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            686..829
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            830..965
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1150
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1272
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1408
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1484
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..2696
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gcgccgcctccggagcccatggccgggacgcgctgggtgctaggggcgttgctccggggctgcggctgcaactgcagcagctgccggcgaaccggtgccgcctgcctgcccttctactcggccgccggcactttcccgtccggcgtctctggccgccgccgcctgctgctactcctcggggccgccgcggccgccgcttcgcagacgcggggcctgcagctcgggcctgcggccgccgggagactggcgggtcccgtccctgtccggccctccgccgccgcggcggctgccgcgtcctactcggcgttgcgcgccccgctgcttccgcgatcgctggccgccgccgcgggcccggcgcggggttactgccaggagtccaaaactacctacctggaagacctcccaccactacctgagtacgaactgagcccatccaagttaggagaagaggtggatgatgtttacctcattcgagctcagggtctgccctggtcctgcactgtggaagatgtcctcagctttttctcagactgcagaatccgaaacagtgagaatggaatacatttcctcctgaacagagatggcaaacggaggggcgatgccttgattgaaatggagtccgagcaggatgtacagaaggccttggaaaagcaccggatgtacatggggcagcggtatgtggaagtgtatgaaataaacaacgaagatgtggatgccttaatgaagagcctacaggtcaagcctacgcctgcactcagtgacggtgtggtccgcctgagaggactcccttacagctgcaatgaaaaggacattgtggacttctttgcaggactgaacatagtagacatcacttttgtgatggactatagagggagaagaaaaacaggggaagcctatgtacagtttgaagaaccagaaatggccaaccaagcgcttctgaagcacagggaagagattggtaaccgatacatagagatatttccaagcagaaggaatgaagttcgcacacacgttggatctcataaaggaaagaaaatggtgtcttctcctactaccaaatatataactgaaccagaagtggtgtttgaggaacatgaagttaatgaggacgctcggcccatgacagcttttgaaagtgaaaaagagatagagttgcctaaggagatgtcagacaaacttgcagaggctgttgactttggagctgtgccgtccctgcattttgtccacatgagaggattgcctttccaagccaatgcccaggacatcataaatttctttgccccactgaagcctgtgagaatcaccatggagtacagctccagcggaaaggccactggagaagctgacgtgcactttgatacccatgaggatgctgttgctgccatgctcaaggaccggtcgcatgtccaacataggtatattgagctgttcctaaattcatgtcctaaaggaaaataagacttgaacagaccccagaagataaggatggagcaggaagcacctcgtttgcacatctctggcataaaaagatgagttgattggcagtggctgctggagaaaggatctgtgcgtctcagtgctgtgtctacaccgagaaagatgcggctgggactctgaaataagcctcacatgtacattttcgtctaagcagtggttgagaaagtcgggcctgtgtgttgagttttctgacacagaggccatattacagacgtgagatgatctttccacccagtgctgctcctcagatccttactcctggttgttgcctctgactgagggctctgatacaaagctcatggaataaattaatggtgtatttttaccaagcactcaccaaagcagcaggaggttcagaactttactaagccagtctgattgggtcaaacagttttgctttttttcattttgattttcatttgattacttagggatagaacttttaaaaaatagcaaaccacagattagtgagtgtaagtgaccactcggcagttttgtctttagaaacactttgcctccttaagcctttgacctgaaagcatttgacgttggtgcctgtctgtgtcttggaaacctagacttcacttccttcacgtttttttggacaaatcttaaggctattaggtttgaaatcgtaatgtgacatatcaaagcagtccagactggtaaggacattaatcgcttcacttgaattaaaccagctctagataagggggaaacaatcttaagtctcctcctctgcttttccagtggggtagccatcccatattttagaacaagtaggggtgccttgcttaaataaaactagcatttcatgtataattgtgtgaaggttctatggctagagctgtatttctgtcacattgtggcagcaccttctgctttaatactaaatagcttgttatttaaatattggataaaatggctggcttcaaaaatagtcattaataaacttaactttatgtatacctgtgtagaagaatcaaagtcctgtatattttctttgccttgttcctattctcagggtgacagctgccaccaagagataataagtctcactcttcagattgaattttctgagctttcagaggtggtaacctggaagaaacgtgtattgcttagttcataaccacctgggattaccagctaaggggcaaaattactgtcctgtagacaataaatgaaggtttcaagtcgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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