LOCUS       NM_001047852            3230 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus BCL2-associated transcription factor 1 (Bclaf1),
            mRNA.
ACCESSION   NM_001047852 XM_001055723 XM_001073455 XM_214967
VERSION     NM_001047852.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3230)
  AUTHORS   Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel
            JA, Saule S, McPherson JP and Goureau O.
  TITLE     Involvement of Bcl-2-associated transcription factor 1 in the
            differentiation of early-born retinal cells
  JOURNAL   J Neurosci 34 (4), 1530-1541 (2014)
   PUBMED   24453340
  REMARK    GeneRIF: Bclaf1 facilitates the differentiation of early retinal
            precursors into retinal ganglion cells, amacrine cells, and
            horizontal cells rather than into cone photoreceptors.
REFERENCE   2  (bases 1 to 3230)
  AUTHORS   Horiuchi K, Kawamura T, Iwanari H, Ohashi R, Naito M, Kodama T and
            Hamakubo T.
  TITLE     Identification of Wilms' tumor 1-associating protein complex and
            its role in alternative splicing and the cell cycle
  JOURNAL   J Biol Chem 288 (46), 33292-33302 (2013)
   PUBMED   24100041
REFERENCE   3  (bases 1 to 3230)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 3230)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 3230)
  AUTHORS   Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S
            and Russo T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   6  (bases 1 to 3230)
  AUTHORS   Liu H, Lu ZG, Miki Y and Yoshida K.
  TITLE     Protein kinase C delta induces transcription of the TP53 tumor
            suppressor gene by controlling death-promoting factor Btf in the
            apoptotic response to DNA damage
  JOURNAL   Mol Cell Biol 27 (24), 8480-8491 (2007)
   PUBMED   17938203
REFERENCE   7  (bases 1 to 3230)
  AUTHORS   Kasof GM, Goyal L and White E.
  TITLE     Btf, a novel death-promoting transcriptional repressor that
            interacts with Bcl-2-related proteins
  JOURNAL   Mol Cell Biol 19 (6), 4390-4404 (1999)
   PUBMED   10330179
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC161968.1.
            
            On Aug 28, 2008 this sequence version replaced NM_001047852.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161968.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3230
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     gene            1..3230
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /note="BCL2-associated transcription factor 1"
                     /db_xref="GeneID:293017"
                     /db_xref="RGD:1309704"
     exon            1..119
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            120..223
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    213..215
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /note="upstream in-frame stop codon"
     exon            224..337
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..2999
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /codon_start=1
                     /product="bcl-2-associated transcription factor 1"
                     /protein_id="NP_001041317.2"
                     /db_xref="GeneID:293017"
                     /db_xref="RGD:1309704"
                     /translation="

MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRIYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTITPQNAPREDSRGRSSFYPDGGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEAPKEKGSEKGRTDGDWDDQEVLDYFSDKESAKQKFHDSEGDDTEETEDYRQFRKSVLADQGKSFATSSHRNTEEEGPKYKSKVSLKGSRESDGFREEKNYKLKETAYIVERPSTTKDKHKDEDKGSDRITVKKEVQSPEQVKSEKLKELFDYSPPLHKSLDAREKSIFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSPAVTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSALRKHTRLAGDERVFKEEIQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKPYRDDSKHKGREQDHSRSSSSSASPSSPSSREEKESKKEREDEFKSHHEMKDYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNPGPNNSNSTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE"

     misc_feature    702..2480
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /note="THRAP3/BCLAF1 family; Region: THRAP3_BCLAF1;
                     pfam15440"
                     /db_xref="CDD:434719"
     misc_feature    <2715..>2912
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /note="CASC3/Barentsz eIF4AIII binding; Region: Btz;
                     cl09653"
                     /db_xref="CDD:447763"
     exon            338..1249
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1915
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2085
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2191
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2192..2276
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2277..2452
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2453..2633
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..2780
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2781..2993
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2994..3207
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gagccgagctagcgcgacgaggccacctctatggtcttcctctccttctggagtcgggaaatggccgctgtgtagttacagcggaggtaaatcctgagaatcgtgcttcggcgtgtcaggaatttgaatttagagtttaatttcctataacattctctacaagaagaatcttggcagtatcttaaagacatcactgacttctggatcctgtataaagcccaaggagaaaagaaatgggccgctccaattctagatcacattcttcaagatccaagtctagatcacagtctagttctagatcaagatcaagatcacattctagaaagaagagatacagttctaggtctcgttccagaacatattcaaggtctcgtagtagagatcgtatttattctagagattatcgtcgggattacaggaataatagaggaatgagacgaccttatgggtacagaggaaggggtagagggtattatcaaggaggaggaggtagatatcaccgaggtggctatagacctgtttggaatagaaggcactctaggagtcctaggcgaggtcggtcacggtccaggagcccgaaaagaagatctgtgtcttctcaaagatcccgaagcagatctcgccggtcatacagatcctctaggtctccaagatcatcatcatctcgttcttcatccccttatagcaaatctcctgtctctaaaagacgagggtctcaggaaaaacagaccaaaaaagctgaaggggaaccccaagaagagagtcctttgaaaagcaaatcacaggaggaaccaaaggatacttttgaacatgatccatctgaatctattgatgagtttaataaatctgctacatctggtgatatttggcctggcctttcagcttatgataatagtccaaggtcacctcatagtccttcacctattgctaccccacccagtcagagttcatcatgctcagatgcccccatgcttagtacagtccactctgccaaaaataccccctctcagcactcacattccattcagcacagtcctgagaggtctggatccggttctgttgggaatgggtctagtcgatatagtccttctcagaatagtccgattcatcacatcccatcacgaagaagccctgcaaagacaatcacaccacagaatgctccaagagaggactctagggggcggtcctctttttatcctgacggaggaggagatcaggaaacagcaaagacaggaaagtttttgaaaaggtttacagatgaagagtctagagtattcctgcttgataggggtaataccagggataaagaggccccaaaggagaaagggtccgagaaaggcaggacagacggagattgggacgatcaggaggttctagattactttagtgataaagagtctgcaaaacaaaagttccatgattctgaaggggatgacacagaggagacagaggattatagacagtttaggaagtcagtcctggcagatcaggggaagagctttgctacttcatctcaccggaatactgaggaggaaggacccaagtacaagtccaaagtttcactaaaaggcagtagagaaagtgatggatttagagaagaaaaaaattataaactgaaagagactgcatacatagtggaaaggcctagcactacaaaggacaagcacaaggacgaagacaaaggctctgacagaataacagtgaagaaagaagtgcagtcaccggagcaggtaaagtctgaaaagctcaaagagctctttgattacagtccccctctacacaagagtctggacgcacgagaaaagtccatcttcagagaggagagcccgctgaggatcaaaatgatagccagtgattctcaccgtcctgaagtcaaactcaaaatggcccctgttcctctggatgactccaacagacctgcctccttgactaaagacaggctacttgctagcacgcttgtccattctgtcaagaaagaacaagaattccgatccatctttgaccacattaagttgcctcaggccagcaaaagcacttcagagtcatttatacaacacattgtatccttggttcatcacgtgaaagagcaatacttcaaatcacctgcagtgaccctaaacgagcggttcacttcataccagaaagctactgaagagcatagtacccggcaaaagagccctgagatacacaggaggattgacatctctccaagcgctctgaggaagcatacccgtttagcaggagacgagagagtttttaaagaagaaattcaaaagggagataaaaaattaaggtgtgattcggctgatcttcggcatgacattgaccgtcgccgcaaagaaagaagtaaagagcggggagattccaagggttcgagggaatctagtggatcaagaaagcaagagaaaacaccaaaggattacaaggagtacaaaccttacagagatgacagcaaacataaagggagagagcaagatcattctcggtcatcgtcctcttcagcatcgccttcgtcacccagctcccgagaagagaaagagagtaagaaagaaagagaagacgagtttaaatctcaccatgagatgaaagactactcaggatttgcaggagttagcaggccacgaggaaccttttttcggatcagaggcagaggaagagcccgaggcgtttttgctgggacaaaccctggtccaaacaactcaaactccactttccaaaagagaccgaaggaagaggagtgggatccagagtataccccaaagagcaagaagtacttcttgcacgatgacagagatgatggtgtggattattgggccaaaagaggaagaggtcgtggtacttttcaacgcggcagagggcgctttaatttcaaaaaatcaggtagcagtccaaaatggactcatgacaaataccaaggagatgggattgttgaggatgaagaggagaccatggaaaataatgaagagaagaaggataggcgcaaagaagaaaaggaatagtctcaagattgcatcagggagcagaacttgacacttaatttttttaaacctgatttttgttttcaaataagaatgtaagcattttacttaaaatgtactgtttgcaagtagtctatagaaattttgttttaagtcttcaaatatcttgaaaatagtagactgtatgttgaaaattgtactgaaataaagtagaagacgttcaatatcaaaaaaaaaaaaaaaaaaaaaaaa

//