LOCUS       NM_001044295            1226 bp    mRNA    linear   ROD 16-MAY-2025
DEFINITION  Rattus norvegicus TPD52 like 1 (Tpd52l1), transcript variant 1,
            mRNA.
ACCESSION   NM_001044295 XM_001070150
VERSION     NM_001044295.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1226)
  AUTHORS   Boutros,R. and Byrne,J.A.
  TITLE     D53 (TPD52L1) is a cell cycle-regulated protein maximally expressed
            at the G2-M transition in breast cancer cells
  JOURNAL   Exp Cell Res 310 (1), 152-165 (2005)
   PUBMED   16112108
REFERENCE   2  (bases 1 to 1226)
  AUTHORS   Cho,S., Ko,H.M., Kim,J.M., Lee,J.A., Park,J.E., Jang,M.S.,
            Park,S.G., Lee,D.H., Ryu,S.E. and Park,B.C.
  TITLE     Positive regulation of apoptosis signal-regulating kinase 1 by
            hD53L1
  JOURNAL   J Biol Chem 279 (16), 16050-16056 (2004)
   PUBMED   14761963
REFERENCE   3  (bases 1 to 1226)
  AUTHORS   Boutros,R., Bailey,A.M., Wilson,S.H. and Byrne,J.A.
  TITLE     Alternative splicing as a mechanism for regulating 14-3-3 binding:
            interactions between hD53 (TPD52L1) and 14-3-3 proteins
  JOURNAL   J Mol Biol 332 (3), 675-687 (2003)
   PUBMED   12963375
REFERENCE   4  (bases 1 to 1226)
  AUTHORS   Byrne,J.A., Nourse,C.R., Basset,P. and Gunning,P.
  TITLE     Identification of homo- and heteromeric interactions between
            members of the breast carcinoma-associated D52 protein family using
            the yeast two-hybrid system
  JOURNAL   Oncogene 16 (7), 873-881 (1998)
   PUBMED   9484778
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On May 16, 2025 this sequence version replaced NM_001044295.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099809.1, CA338998.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               JAXUCZ010000001.1  27991235-27991356
            123-238             JAXUCZ010000001.1  28077246-28077361
            239-387             JAXUCZ010000001.1  28084611-28084759
            388-489             JAXUCZ010000001.1  28097414-28097515
            490-528             JAXUCZ010000001.1  28102864-28102902
            529-589             JAXUCZ010000001.1  28105495-28105555
            590-606             JAXUCZ010000001.1  28107329-28107345
            607-1226            JAXUCZ010000001.1  28109148-28109767
FEATURES             Location/Qualifiers
     source          1..1226
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..1226
                     /gene="Tpd52l1"
                     /note="TPD52 like 1"
                     /db_xref="GeneID:689256"
                     /db_xref="RGD:1594796"
     exon            1..122
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..595
                     /gene="Tpd52l1"
                     /note="isoform 1 is encoded by transcript variant 1; tumor
                     protein D53; tumor protein D52-like 1"
                     /codon_start=1
                     /product="tumor protein D53 isoform 1"
                     /protein_id="NP_001037760.1"
                     /db_xref="GeneID:689256"
                     /db_xref="RGD:1594796"
                     /translation="

MEAQAQGLLETEPLQGRDGDAIGSADLSSMLSEEEKDELKAELVQLEEEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSRSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISRKFGDMRYSIRHSISMPAMRNSPTFKSFEERVETTVTSLKV"

     misc_feature    194..556
                     /gene="Tpd52l1"
                     /note="Tumour protein D52 family; Region: TPD52;
                     pfam04201"
                     /db_xref="CDD:461225"
     exon            123..238
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            239..387
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            388..489
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            490..528
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            529..589
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            590..606
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            607..1226
                     /gene="Tpd52l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggcggcgtggctggcagtcttccgagctcgggcaccgctaccatctgctgctctgcgaggagtccgtggattccccgccgcgctcagctccacgccggccaccatggaggcgcaggcacaaggcttgttggagacggagccacttcaaggaagagatggggacgcaataggcagtgctgacctctctagcatgctttctgaggaggagaaggacgagctaaaggcagagttagttcagctagaagaggaaatcacaacattacgacaagttttgtcagcaaaagaaagacatctggttgagatcaaacagaaactcggcatgaacctgatgaacgagttaaagcagaacttcagcaggagctggcacgacatgcagaccacgactgcgtacaaaaaaacacacgaaaccctgagccacgcagggcagaaggcaacagcagctttcagtaatgtgggaactgccatcagcaggaagtttggcgatatgaggtactccatccgccattccataagtatgcctgccatgaggaattctcctactttcaaatcatttgaggagagggttgagacaactgttacaagcctcaaggtgtaaatgttttgcctacgaaagtaggtgggacaaaccacagtggtggcagttttgaggaggtcctgagctccacagcacacgccagctcccagaatgcttcagcaggcatccggcagaccagagaagaggatctgcagtgctaggcccagcctgggctgctgccggtcagtttgcctgctcatcccgttatgaagaccaaaatcccaccgggaaccccaagttttgacattgttatttaaatggggtctccaaaaagtttaatgaaatgatttctcttcgcacttgtgttgacgatggaccagtcgaccattactctggagtgtttacaaatgtcacctttaaaataggcaacctggagcacggtcctaactggtcctattcttgtctgtgtaactcaatgtatttcccaaacatgcagctactaattattagctttgcttttggctcagtctccataccactatgcatgtctgggagtgctgaggcctgtcagtgtgcagagccacaggggcactatttgatgactgtcgcctccagctggccaagtcactccaaacttcaccaaattgcttgtgatctctcacctacatcaatgtacatctatttaagtcattaaaataattcactatagcga

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