LOCUS       NM_001024328            1297 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus GTPase, IMAP family member 7 (Gimap7), mRNA.
ACCESSION   NM_001024328 XM_575465
VERSION     NM_001024328.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Schwefel D, Arasu BS, Marino SF, Lamprecht B, Kochert K, Rosenbaum
            E, Eichhorst J, Wiesner B, Behlke J, Rocks O, Mathas S and Daumke
            O.
  TITLE     Structural insights into the mechanism of GTPase activation in the
            GIMAP family
  JOURNAL   Structure 21 (4), 550-559 (2013)
   PUBMED   23454188
REFERENCE   2  (bases 1 to 1297)
  AUTHORS   Dion C, Carter C, Hepburn L, Coadwell WJ, Morgan G, Graham M, Pugh
            N, Anderson G, Butcher GW and Miller JR.
  TITLE     Expression of the Ian family of putative GTPases during T cell
            development and description of an Ian with three sets of
            GTP/GDP-binding motifs
  JOURNAL   Int Immunol 17 (9), 1257-1268 (2005)
   PUBMED   16103028
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CV075794.1 and BC091210.1.
            
            On Oct 1, 2005 this sequence version replaced NM_001024328.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ232730.1, DQ125348.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                CV075794.1         1-54
            55-1297             BC091210.1         1-1243
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..1297
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="GTPase, IMAP family member 7"
                     /db_xref="GeneID:500113"
                     /db_xref="RGD:1565750"
     exon            1..73
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /inference="alignment:Splign:2.1.0"
     exon            74..1271
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..992
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /codon_start=1
                     /product="GTPase, IMAP family member 7"
                     /protein_id="NP_001019499.1"
                     /db_xref="GeneID:500113"
                     /db_xref="RGD:1565750"
                     /translation="

MAELDDDSLRIVLVGKTGSGKSATANTILGQKIFTSRIAPHAVTQTCQKASRRWKERDLLVVDTPGLFDTKVNLETTSIEISRCVLQSCPGPHAIILVLQLNRFTIEEQETVTRIKAIFGKAVMKYLIILFTRKDELEDQNLNDFIEDSDTNLKSIIKECDSRYLAINNKAEGAEGEMQVQELMGFVESLVRSNGGLYFSDPIYKYAEQRLKKQVGILREIYTDVLEKEIRIVEEECGLGKLSTQEGEEKIQAIREKYNLKIGNLREAAEKNIFTWIVEEVKKVLLKIWHFFS"

     misc_feature    135..737
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="AvrRpt2-Induced Gene 1 (AIG1); Region: AIG1;
                     cd01852"
                     /db_xref="CDD:206651"
     misc_feature    153..176
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="G1 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    order(162..179,216..218,507..509,513..515,615..620)
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206651"
     misc_feature    237..260
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206651"
     misc_feature    240..242
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="G2 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    297..308
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="G3 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    order(303..311,339..392)
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206651"
     misc_feature    504..515
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="G4 box; other site"
                     /db_xref="CDD:206651"
     misc_feature    591..599
                     /gene="Gimap7"
                     /gene_synonym="Ian3"
                     /note="G5 box; other site"
                     /db_xref="CDD:206651"
ORIGIN      

gttccttcagggtttgtagaactgcagccagattccttgaggacagtgtgagagctcatctgtcctgcagaagtcaaggcacctggattccagagcttccacatcagaccatggctgaactggatgatgactctctgaggattgttctggtagggaaaacaggaagtggaaagagcgccacagcaaacaccatcctggggcaaaagatatttacttctagaatcgcaccccacgctgtcacccagacctgtcagaaggcatcccgcaggtggaaggaaagagacctcctggttgttgacaccccaggactcttcgacaccaaggtgaacctggaaaccaccagcattgaaatcagccggtgtgtccttcagtcctgccccgggcctcatgccatcattcttgttctgcaactgaatcgcttcacgatagaagagcaagagaccgttactaggatcaaggctatctttgggaaggcagtcatgaagtacctgatcatcttgttcacccgcaaagacgagttggaggaccagaacctaaacgatttcattgaagactcagatactaaccttaaaagcatcatcaaggagtgtgacagccgctatctggccatcaataacaaagcggagggggctgagggggaaatgcaggtgcaggaactgatggggtttgtagaatccctggtgcgcagcaatggcgggctctacttctctgatcccatatacaagtatgcagagcaaaggctgaagaaacaagtggggatcttgagggaaatttacactgacgtactagagaaggagattagaatagtggaggaggagtgtggtcttgggaaacttagtactcaggaaggagaggaaaaaatacaagccattagggaaaaatacaacctgaagataggaaacctacgtgaagcagcagagaaaaacatattcacttggattgttgaagaagttaagaaagttcttttgaaaatatggcattttttttcttaaggagtctgaattttttttccatttattctgagcatttcttccagctcactctctacaactcaccctgctggccctttcctacagccaccagccaccggcagatttaagagatagcaaacccaggaattcaatgcaccagggtcaggactcagtgtcaggctccaaggctggatcacacttggcgctcagctccctatgctagcctgtcctcccgttcccaccatgatgaactgaaatgactttgtaaccatgagcccaaataaacactgctatctttaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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