LOCUS       NM_001012749            1443 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus Ly49 stimulatory receptor 5 (Ly49s5), mRNA.
ACCESSION   NM_001012749
VERSION     NM_001012749.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Naper C, Dai KZ, Kveberg L, Rolstad B, Niemi EC, Vaage JT and Ryan
            JC.
  TITLE     Two structurally related rat Ly49 receptors with opposing functions
            (Ly49 stimulatory receptor 5 and Ly49 inhibitory receptor 5)
            recognize nonclassical MHC class Ib-encoded target ligands
  JOURNAL   J Immunol 174 (5), 2702-2711 (2005)
   PUBMED   15728478
  REMARK    GeneRIF: Ly49s5 is a stimulatory receptor structurally related to
            Ly49i5 that recognizes ligands encoded within the
            histocompatibility class Ib region of the rat u haplotype.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY649832.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: AY846265.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN16676786 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="PVG"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1443
                     /gene="Ly49s5"
                     /note="Ly49 stimulatory receptor 5"
                     /db_xref="GeneID:503662"
                     /db_xref="RGD:1359728"
     exon            1..115
                     /gene="Ly49s5"
                     /inference="alignment:Splign:2.1.0"
     exon            116..282
                     /gene="Ly49s5"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    141..143
                     /gene="Ly49s5"
                     /note="upstream in-frame stop codon"
     CDS             171..1004
                     /gene="Ly49s5"
                     /codon_start=1
                     /product="Ly49 stimulatory receptor 5"
                     /protein_id="NP_001012767.1"
                     /db_xref="GeneID:503662"
                     /db_xref="RGD:1359728"
                     /translation="

MSEQEVPCSTVRFKKSSGLRYQVRPKETQRPREAGCRVPWQLTVIAIGILLSLRLVAVAMLVTNIFQFSHEKHELQKTRNRHPNCSTMEKDINLKEETLRTMSVECTSSNALLDLFNREQNRWYKKTKTVLASPQHPARCVEMHWFCHGIKCYYFIMDIRTWHECKQTCQNYNLSFLKIDDKDELKFLQDHIIRDSYWVGLSYNNIKKEWSWIDSSPLNCDLLACKPLQKTGYCIYFSMTGLHYDDCGKRHLCICEKGMDKIPAPLCSVKERSQSAV"

     misc_feature    282..635
                     /gene="Ly49s5"
                     /note="Ly49-like protein, N-terminal region; Region: Ly49;
                     pfam08391"
                     /db_xref="CDD:429969"
     misc_feature    594..941
                     /gene="Ly49s5"
                     /note="C-type lectin-like domain (CTLD) of the type found
                     in natural killer cell receptors (NKRs); Region:
                     CLECT_NK_receptors_like; cd03593"
                     /db_xref="CDD:153063"
     misc_feature    order(756..758,840..842,891..893,897..902)
                     /gene="Ly49s5"
                     /note="ligand binding surface [chemical binding]; other
                     site"
                     /db_xref="CDD:153063"
     exon            283..363
                     /gene="Ly49s5"
                     /inference="alignment:Splign:2.1.0"
     exon            364..582
                     /gene="Ly49s5"
                     /inference="alignment:Splign:2.1.0"
     exon            583..725
                     /gene="Ly49s5"
                     /inference="alignment:Splign:2.1.0"
     exon            726..829
                     /gene="Ly49s5"
                     /inference="alignment:Splign:2.1.0"
     exon            830..1424
                     /gene="Ly49s5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctcagaggaaagttagttttgtctttcatctgggagcctctttgtggatacagaccgggaaaggtcaactctttccagtactttccaactgaatcacattgggatagagacacagaaaacactcaatgccggattttaactgaaaacagacttcatacatcactcccaaaatgagtgagcaagaggttccttgctcaactgtgagatttaaaaagtcttcagggttgaggtaccaagtgaggcctaaggagactcaaagacccagggaagctggctgcagagtcccctggcagctcactgtgattgctattggaatccttctttcccttcggctggttgctgttgcaatgttggtgacaaacatttttcagtttagtcatgaaaaacatgaactgcagaaaactcgaaaccgtcaccctaactgcagcaccatggaaaaggacatcaacttaaaggaagaaacgctgagaactatgtctgtagagtgtacttccagcaatgcgcttctggacttattcaacagagaacagaacagatggtacaaaaaaactaagactgttttagcttcccctcagcacccagccaggtgtgttgaaatgcactggttctgccatggtataaaatgttattatttcatcatggacataagaacatggcatgaatgtaaacagacctgccagaactacaacttatcctttctgaagatagatgataaggatgaactgaagttcctccaggaccacattattcgagacagttactgggttggattgtcatataataatataaaaaaggaatggtcatggattgacagcagtccattgaattgtgatttgttggcatgtaaaccactacaaaaaacaggatactgtatatatttcagtatgacaggtctacattatgatgactgtggtaaaagacatctctgtatctgtgaaaagggaatggacaaaatccctgctccattgtgcagtgtgaaggaaaggtcacagtctgctgtgtgaagagagagatgaggtccacagggaagaaatctgctgaaaattggctcaacggcagacacagtaatcccttctggcacatgaggagcttgcatgtggagagtggacatcctttgctccaagacccaaatgattccctcacattgtctcctgaatgacacagaggaccacatggagaactcgataaataatgaatgtatcaaatcgtcattaggatatttccatagcccatggcttgatagcacaattaataattaatctgcagttatgttttcatgtgttggttagttactctttgttatttttttggtgtagaaaaagttagcatttttaataaccttttgagatgaagaactgtggaaatgaggtctgatgggagtggtgtctggactgttaataaataaaataattttgaaaaccttaaaaaaaaaaaaaaaaaaaa

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