LOCUS       NM_001009501            1408 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus Ly49 inhibitory receptor 5 (Ly49i5), mRNA.
ACCESSION   NM_001009501 XM_579301
VERSION     NM_001009501.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1408)
  AUTHORS   Naper C, Dai KZ, Kveberg L, Rolstad B, Niemi EC, Vaage JT and Ryan
            JC.
  TITLE     Two structurally related rat Ly49 receptors with opposing functions
            (Ly49 stimulatory receptor 5 and Ly49 inhibitory receptor 5)
            recognize nonclassical MHC class Ib-encoded target ligands
  JOURNAL   J Immunol 174 (5), 2702-2711 (2005)
   PUBMED   15728478
  REMARK    GeneRIF: Ly49i5 is an inhibitory receptor structurally related to
            Ly49i5 that recognizes ligands encoded within the
            histocompatibility class Ib region of rat u and l haplotypes.
REFERENCE   2  (bases 1 to 1408)
  AUTHORS   Nylenna O, Naper C, Vaage JT, Woon PY, Gauguier D, Dissen E, Ryan
            JC and Fossum S.
  TITLE     The genes and gene organization of the Ly49 region of the rat
            natural killer cell gene complex
  JOURNAL   Eur J Immunol 35 (1), 261-272 (2005)
   PUBMED   15593300
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000151.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001009501.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY649836.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA5760400, SAMN06680416
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                JACYVU010000151.1  326427-326493       c
            68-266              JACYVU010000151.1  324617-324815       c
            267-356             JACYVU010000151.1  323152-323241       c
            357-566             JACYVU010000151.1  322070-322279       c
            567-709             JACYVU010000151.1  320901-321043       c
            710-813             JACYVU010000151.1  314448-314551       c
            814-1408            JACYVU010000151.1  300800-301394       c
FEATURES             Location/Qualifiers
     source          1..1408
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1408
                     /gene="Ly49i5"
                     /note="Ly49 inhibitory receptor 5"
                     /db_xref="GeneID:494211"
                     /db_xref="RGD:1359210"
     exon            1..67
                     /gene="Ly49i5"
                     /inference="alignment:Splign:2.1.0"
     exon            68..266
                     /gene="Ly49i5"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    104..106
                     /gene="Ly49i5"
                     /note="upstream in-frame stop codon"
     CDS             155..988
                     /gene="Ly49i5"
                     /note="killer cell lectin-like receptor family A member"
                     /codon_start=1
                     /product="Ly49 inhibitory receptor 5"
                     /protein_id="NP_001009501.1"
                     /db_xref="GeneID:494211"
                     /db_xref="RGD:1359210"
                     /translation="

MTEQEVTYTTVRFHKSSVFQNEVRSEETQSAKEIGHRESSVPWKLIVIALGILCLLLLVTVAVLVTNIFQYRHELQKTRNRHHNCSTMENDINLKEETLRNMSVQCIPSNTLLNLFNREQNRWYKKTKTVLASPQHTARCVEMHWFCHGIKCYYFIMDIRTWHECKQTCQNYNLSFLKIDDKDELKFLQEHFIRESYWIGLSYNNIKKEWSWIDNSPLNCDLLACKPLQKTGYCIYFSMTGLHYDDCGKRHLCICEKGMDKITAPLCSVKERSQSAA"

     misc_feature    272..619
                     /gene="Ly49i5"
                     /note="Ly49-like protein, N-terminal region; Region: Ly49;
                     pfam08391"
                     /db_xref="CDD:429969"
     misc_feature    578..925
                     /gene="Ly49i5"
                     /note="C-type lectin-like domain (CTLD) of the type found
                     in natural killer cell receptors (NKRs); Region:
                     CLECT_NK_receptors_like; cd03593"
                     /db_xref="CDD:153063"
     misc_feature    order(740..742,824..826,875..877,881..886)
                     /gene="Ly49i5"
                     /note="ligand binding surface [chemical binding]; other
                     site"
                     /db_xref="CDD:153063"
     exon            267..356
                     /gene="Ly49i5"
                     /inference="alignment:Splign:2.1.0"
     exon            357..566
                     /gene="Ly49i5"
                     /inference="alignment:Splign:2.1.0"
     exon            567..709
                     /gene="Ly49i5"
                     /inference="alignment:Splign:2.1.0"
     exon            710..813
                     /gene="Ly49i5"
                     /inference="alignment:Splign:2.1.0"
     exon            814..1408
                     /gene="Ly49i5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggtcaatttctccaccaattgggtgaccaatttcctccacgagaatcgcatcgggatagagacacagatctaggtaccttcctataggtgaacatttaaaatttgaaaaaaaaacaattctcaaggctccagtatacttcatatattccagaagatgactgagcaagaggttacttacacaactgtgagatttcataagtcgtcagtgttccagaacgaagtgaggtctgaggagactcaaagtgctaaagaaattggccacagagagagttcagtcccctggaagctcattgtgatagctcttggaatcctctgtttacttctgctggttactgttgcagtattggtaacaaacatttttcagtatagacatgaacttcagaaaacccgaaaccgtcaccataactgcagcaccatggaaaatgatatcaacttaaaggaagaaacgttgagaaatatgtctgtacagtgtattcccagcaatactcttctgaacttattcaacagagaacaaaacagatggtacaaaaaaactaagactgttttagcttcccctcagcacacagccaggtgtgttgaaatgcactggttctgccatggtataaaatgttattatttcatcatggacataagaacatggcatgaatgtaaacagacctgccagaactacaacttatcctttctgaagattgatgataaggatgaactgaagttccttcaggaacactttattcgagaaagttactggattggattgtcatataataatataaaaaaggaatggtcatggattgacaacagcccgttgaattgtgatttgttggcatgtaaaccactacaaaaaaccggatactgtatatatttcagtatgacaggtctacattatgatgactgtggtaaaagacatctctgtatctgtgaaaaagggatggacaaaatcactgccccattgtgcagtgtgaaggaaaggtcacagtctgctgcatgaatagagagatgaggtccacagggaagaaatctgctgaaaattgactgaacagcagacacagtaatccgttctggcacatgaagcagcttgcatgtggagaatggacatcctttgctccaatacccaaacaattccctcacattgtctcatgaatgacacaggaccacatggagaactcaataaagaatgaatctatcaaatcgtcattaggatatttccatagaccatggcttgatagcacaattaataactaacctgcagttgtgggttttcatgtgttggtttgttactctttgatatatttttggtgtagaaaaagttagcatttttaatagccttttgaaatgaagaactgtggaagggaggtctgatggggtgatgtctggactgttaataaataaaataattttgaaaacctta

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