LOCUS       NM_001401527            1173 bp    mRNA    linear   PLN 01-JAN-2023
DEFINITION  Oryza sativa Japonica Group rac-like GTP-binding protein 1
            (LOC4325879), mRNA.
ACCESSION   NM_001401527 XM_015766159
VERSION     NM_001401527.1
KEYWORDS    RefSeq.
SOURCE      Oryza sativa Japonica Group (Japanese rice)
  ORGANISM  Oryza sativa Japonica Group
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP
            clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Wang Q, Li Y, Ishikawa K, Kosami KI, Uno K, Nagawa S, Tan L, Du J,
            Shimamoto K and Kawano Y.
  TITLE     Resistance protein Pit interacts with the GEF OsSPK1 to activate
            OsRac1 and trigger rice immunity
  JOURNAL   Proc Natl Acad Sci U S A 115 (49), E11551-E11560 (2018)
   PUBMED   30446614
  REMARK    GeneRIF: This study concluded that OsSPK1 is a direct and key
            signaling target of Pit-mediated immunity via RAC1 activation.
REFERENCE   2  (bases 1 to 1173)
  AUTHORS   Yamaguchi K, Imai K, Akamatsu A, Mihashi M, Hayashi N, Shimamoto K
            and Kawasaki T.
  TITLE     SWAP70 functions as a Rac/Rop guanine nucleotide-exchange factor in
            rice
  JOURNAL   Plant J 70 (3), 389-397 (2012)
   PUBMED   22142166
  REMARK    GeneRIF: Reduction of OsSWAP70A and OsSWAP70B mRNA levels by RNA
            interference resulted in the suppression of chitin elicitor-induced
            defense gene expression and ROS production. It is likely that
            OsSWAP70 regulates immune responses through activation of OsRac1.
REFERENCE   3  (bases 1 to 1173)
  AUTHORS   Fujiwara M, Hamada S, Hiratsuka M, Fukao Y, Kawasaki T and
            Shimamoto K.
  TITLE     Proteome analysis of detergent-resistant membranes (DRMs)
            associated with OsRac1-mediated innate immunity in rice
  JOURNAL   Plant Cell Physiol 50 (7), 1191-1200 (2009)
   PUBMED   19502382
  REMARK    GeneRIF: OsRac1-mediated innate immunity is associated with
            detergent-resistant membranes.
REFERENCE   4  (bases 1 to 1173)
  AUTHORS   Kikuchi S, Satoh K, Nagata T, Kawagashira N, Doi K, Kishimoto N,
            Yazaki J, Ishikawa M, Yamada H, Ooka H, Hotta I, Kojima K, Namiki
            T, Ohneda E, Yahagi W, Suzuki K, Li CJ, Ohtsuki K, Shishiki T,
            Otomo Y, Murakami K, Iida Y, Sugano S, Fujimura T, Suzuki Y,
            Tsunoda Y, Kurosaki T, Kodama T, Masuda H, Kobayashi M, Xie Q, Lu
            M, Narikawa R, Sugiyama A, Mizuno K, Yokomizo S, Niikura J, Ikeda
            R, Ishibiki J, Kawamata M, Yoshimura A, Miura J, Kusumegi T, Oka M,
            Ryu R, Ueda M, Matsubara K, Kawai J, Carninci P, Adachi J, Aizawa
            K, Arakawa T, Fukuda S, Hara A, Hashizume W, Hayatsu N, Imotani K,
            Ishii Y, Itoh M, Kagawa I, Kondo S, Konno H, Miyazaki A, Osato N,
            Ota Y, Saito R, Sasaki D, Sato K, Shibata K, Shinagawa A, Shiraki
            T, Yoshino M, Hayashizaki Y and Yasunishi A.
  CONSRTM   Rice Full-Length cDNA Consortium; National Institute of
            Agrobiological Sciences Rice Full-Length cDNA Project Team;
            Foundation of Advancement of International Science Genome
            Sequencing & Analysis Group; RIKEN
  TITLE     Collection, mapping, and annotation of over 28,000 cDNA clones from
            japonica rice
  JOURNAL   Science 301 (5631), 376-379 (2003)
   PUBMED   12869764
  REMARK    Erratum:[Science. 2003 Sep;301(5641):1849]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CI594958.1, AK071126.1, CI241725.1 and AU030691.1.
            
            On Feb 15, 2022 this sequence version replaced XM_015766159.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN03003383
                              [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-412               CI594958.1         1-412
            413-471             AK071126.1         413-471
            472-873             CI241725.1         1-402
            874-1173            AU030691.1         288-587
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Oryza sativa Japonica Group"
                     /mol_type="mRNA"
                     /db_xref="taxon:39947"
                     /chromosome="1"
                     /map="1"
     gene            1..1173
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="rac-like GTP-binding protein 1"
                     /db_xref="GeneID:4325879"
     exon            1..233
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    66..68
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="upstream in-frame stop codon"
     CDS             123..767
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="LOC_Os01g12900"
                     /codon_start=1
                     /product="rac-like GTP-binding protein 1"
                     /protein_id="NP_001388456.1"
                     /db_xref="GeneID:4325879"
                     /translation="

MSSAAAATRFIKCVTVGDGAVGKTCMLICYTCNKFPTDYIPTVFDNFSANVSVDGSVVNLGLWDTAGQEDYSRLRPLSYRGADVFILSFSLISRASYENVQKKWMPELRRFAPGVPVVLVGTKLDLREDRAYLADHPASSIITTEQGEELRKLIGAVAYIECSSKTQRNIKAVFDTAIKVVLQPPRHKDVTRKKLQSSSNRPVRRYFCGSACFA"

     misc_feature    150..668
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="Rho-related protein from plants (Rop)-like; Region:
                     Rop_like; cd04133"
                     /db_xref="CDD:206705"
     misc_feature    order(156..158,246..251,255..260,264..266,270..272,
                     297..299,309..314,318..326,342..344,351..353)
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="putative GEF (guanine nucleotide exchange factor)
                     interaction site [polypeptide binding]; other site"
                     /db_xref="CDD:206705"
     misc_feature    171..194
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="G1 box; other site"
                     /db_xref="CDD:206705"
     misc_feature    order(180..197,312..317,321..323,489..491,495..497,
                     612..617)
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206705"
     misc_feature    237..263
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9SSX0.1);
                     Region: Effector region. /evidence=ECO:0000255"
     misc_feature    243..263
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206705"
     misc_feature    246..248
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="G2 box; other site"
                     /db_xref="CDD:206705"
     misc_feature    order(249..251,318..320,342..344,348..350)
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="putative GDI (guanine nucleotide dissociation
                     inhibitor) interaction [active]"
                     /db_xref="CDD:206705"
     misc_feature    order(249..254,324..326,342..344)
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="putative GAP (GTPase-activating protein)
                     interaction site [polypeptide binding]; other site"
                     /db_xref="CDD:206705"
     misc_feature    order(252..257,342..344,351..353)
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="putative effector interaction site [active]"
                     /db_xref="CDD:206705"
     misc_feature    312..323
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="G3 box; other site"
                     /db_xref="CDD:206705"
     misc_feature    order(321..326,342..353,366..374)
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206705"
     misc_feature    486..497
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="G4 box; other site"
                     /db_xref="CDD:206705"
     misc_feature    609..617
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /note="G5 box; other site"
                     /db_xref="CDD:206705"
     exon            234..321
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
     exon            322..431
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
     exon            432..495
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
     exon            496..560
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
     exon            561..626
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
     exon            627..733
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
     exon            734..1157
                     /gene="LOC4325879"
                     /gene_synonym="OsRac1; Rac1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggcaagttcaaacggagctggaggcagagctagagtgagactgtgagagtgaacaagagataagctaagctagtacagcaaccagcaagaacaaagaagagtggccggagtgggcgggggagatgagctcggcggcggcggcgacgaggttcatcaagtgcgtcaccgtgggggacggcgcggtggggaagacgtgcatgctcatctgctacacctgcaacaagttccccaccgattacatccccaccgtgttcgacaacttcagcgccaatgtctccgtggacgggagcgtcgtcaacctcggcctctgggacactgcaggtcaggaggattacagcaggttgaggcctctgagctacaggggagccgatgtgttcatcctgtccttctccctgataagcagggcgagctatgagaatgttcagaagaagtggatgccagagcttcgccggtttgcgcctggtgttcctgtagttcttgttggaaccaagttggatctccgtgaagatagggcctatcttgctgatcatccagcttcttccataataacaacggagcagggagaagaactgaggaagctaataggagcggtcgcctacatcgaatgcagctccaagacacagagaaacattaaagctgttttcgacactgccatcaaagtggtgcttcaacctccaagacataaggatgtaaccagaaagaaactccaatcaagctccaatcggccagtaaggcggtacttttgcggaagcgcttgtttcgcgtagtcaataaccaagaagaaaaaaatgtggtttttgttccatcaccatgatgttcagatggccccatggatctactcagaatgggatagaagatcatggttgaatcaacattgcttgcagctaggaggaacttctagttctctttttttctgcagtggagctccttttgtttctcctttctctttttttcttatgttgtaaaagctccagaaagttttacccttggtaataagatgtgctcttctggatggctacctttacccgtatctcctttcactttgcgaaatgttggaaactactggacctaacagacctaacagacaaacaaaaaagaagccacatgcttcaaccttttcttatatactttggattgaatacataggaagttaattaaaaaaaaaaaaaaaaa

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