2025-04-05 08:43:23, GGRNA.v2 : RefSeq release 228 (Jan, 2025)
LOCUS NR_130333 84 bp RNA linear ROD 23-FEB-2021 DEFINITION Mus musculus microRNA 466m (Mir466m), microRNA. ACCESSION NR_130333 VERSION NR_130333.1 KEYWORDS RefSeq. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 1 to 84) AUTHORS Ji Q, Pan C, Wang J, Yang Z, Li C, Yang C, Zhang W, Wang M, Dong M, Sun Z and Nie S. TITLE Long non-coding RNA Hsp4 alleviates lipopolysaccharide-induced apoptosis of lung epithelial cells via miRNA-466m-3p/DNAjb6 axis JOURNAL Exp Mol Pathol 117, 104547 (2020) PUBMED 32976821 REMARK GeneRIF: Long non-coding RNA Hsp4 alleviates lipopolysaccharide-induced apoptosis of lung epithelial cells via miRNA-466m-3p/DNAjb6 axis. REFERENCE 2 (bases 1 to 84) AUTHORS Polikepahad S and Corry DB. TITLE Profiling of T helper cell-derived small RNAs reveals unique antisense transcripts and differential association of miRNAs with argonaute proteins 1 and 2 JOURNAL Nucleic Acids Res 41 (2), 1164-1177 (2013) PUBMED 23185045 REFERENCE 3 (bases 1 to 84) AUTHORS Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C and Bartel DP. TITLE Mammalian microRNAs: experimental evaluation of novel and previously annotated genes JOURNAL Genes Dev 24 (10), 992-1009 (2010) PUBMED 20413612 REFERENCE 4 (bases 1 to 84) AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ. TITLE miRBase: microRNA sequences, targets and gene nomenclature JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006) PUBMED 16381832 COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation provided by NCBI staff in collaboration with miRBase. The reference sequence was derived from AL772216.15. Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. ##Evidence-Data-START## Transcript is intronless :: SRR7345562.2290708.1, SRR7652917.383295.1 [ECO:0000345] ##Evidence-Data-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-84 AL772216.15 42697-42780 FEATURES Location/Qualifiers source 1..84 /organism="Mus musculus" /mol_type="transcribed RNA" /strain="C57BL/6" /db_xref="taxon:10090" /chromosome="2" /map="2 8.22 cM" gene 1..84 /gene="Mir466m" /gene_synonym="mmu-mir-466m" /note="microRNA 466m" /db_xref="GeneID:100526481" /db_xref="MGI:MGI:4834277" /db_xref="miRBase:MI0014050" precursor_RNA 1..84 /gene="Mir466m" /gene_synonym="mmu-mir-466m" /product="microRNA 466m" /db_xref="GeneID:100526481" /db_xref="MGI:MGI:4834277" /db_xref="miRBase:MI0014050" exon 1..84 /gene="Mir466m" /gene_synonym="mmu-mir-466m" /inference="alignment:Splign:2.1.0" ncRNA 15..37 /ncRNA_class="miRNA" /gene="Mir466m" /gene_synonym="mmu-mir-466m" /product="mmu-miR-466m-5p" /db_xref="miRBase:MIMAT0014882" /db_xref="GeneID:100526481" /db_xref="MGI:MGI:4834277" /db_xref="miRBase:MI0014050" ncRNA 51..72 /ncRNA_class="miRNA" /gene="Mir466m" /gene_synonym="mmu-mir-466m" /product="mmu-miR-466m-3p" /db_xref="miRBase:MIMAT0014883" /db_xref="GeneID:100526481" /db_xref="MGI:MGI:4834277" /db_xref="miRBase:MI0014050" ORIGIN
tgtgtgtgttcttgtgtgtgcatgtgcatgtgtgtatatgaatatacatatacatacacacatacacacgcacgtacacacaca
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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