LOCUS       NM_029007               3402 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus LRAT domain containing 1 (Lratd1), mRNA.
ACCESSION   NM_029007
VERSION     NM_029007.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3402)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3402)
  AUTHORS   Hoffmann,S., Schmitteckert,S., Raedecke,K., Rheinert,D.,
            Diebold,S., Roeth,R., Weiss,B., Granzow,M., Niesler,B.,
            Griesbeck,A., Eckstein,V., Zimmermann,W.H., Just,S. and
            Rappold,G.A.
  TITLE     Network-driven discovery yields new insight into Shox2-dependent
            cardiac rhythm control
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1864 (4-5), 194702 (2021)
   PUBMED   33706013
REFERENCE   3  (bases 1 to 3402)
  AUTHORS   Kamino,H., Yamazaki,Y., Saito,K., Takizawa,D., Kakizaki,S.,
            Moore,R. and Negishi,M.
  TITLE     Nuclear receptor CAR-regulated expression of the FAM84A gene during
            the development of mouse liver tumors
  JOURNAL   Int J Oncol 38 (6), 1511-1520 (2011)
   PUBMED   21424122
  REMARK    GeneRIF: FAM84A is up-regulated by CAR during the development of
            liver tumors.
REFERENCE   4  (bases 1 to 3402)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   5  (bases 1 to 3402)
  AUTHORS   Muhlfriedel,S., Kirsch,F., Gruss,P., Chowdhury,K. and Stoykova,A.
  TITLE     Novel genes differentially expressed in cortical regions during
            late neurogenesis
  JOURNAL   Eur J Neurosci 26 (1), 33-50 (2007)
   PUBMED   17614941
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC005488.1.
            
            On Jun 9, 2003 this sequence version replaced NM_029007.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC005488.1, SRR1660817.295640.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3402
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 6.93 cM"
     gene            1..3402
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /note="LRAT domain containing 1"
                     /db_xref="GeneID:105005"
                     /db_xref="MGI:MGI:2145011"
     exon            1..217
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    179..181
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /note="upstream in-frame stop codon"
     exon            218..3380
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /inference="alignment:Splign:2.1.0"
     CDS             254..1132
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /note="protein FAM84A; family with sequence similarity 84,
                     member A"
                     /codon_start=1
                     /product="protein LRATD1"
                     /protein_id="NP_083283.2"
                     /db_xref="CCDS:CCDS25820.1"
                     /db_xref="GeneID:105005"
                     /db_xref="MGI:MGI:2145011"
                     /translation="

MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDEEEDLDERGQPDKFGVKGPPGCSPCPESPSRHHHHLLHQLVLNETQFSAFRGQECIFSKVTGGPQGADLSVYAVTALPAICEPGDLLELLWLQPATEQPAPAPHWAVYVGGGQIIHLHQGEIRQDSLYQAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLEENKVHTARFHSLEDLIREKRRIDASGRLRVLQELEDFVDDKE"

     misc_feature    365..367
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q96KN4; propagated from
                     UniProtKB/Swiss-Prot (Q9D650.1); phosphorylation site"
     misc_feature    680..922
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /note="NlpC/P60 family; Region: NLPC_P60; cl21534"
                     /db_xref="CDD:473902"
     regulatory      3361..3366
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /note="hexamer: ATTAAA"
     polyA_site      3380
                     /gene="Lratd1"
                     /gene_synonym="2310003N02Rik; 4731402F03Rik; Fam84a; Nse1"
                     /note="major polyA site"
ORIGIN      

caggacttgccaggtggagcagacgcccaagccagcgtagacacggagcgcatccgcaccgctctgggtacctcacctcactgctcgtctccggatagatcggaaccgcagtcccacgcgactccaggacccactcgccactgccgcctccacagcacccatggggacctggagactttaaaaggagtttggggtttcgggcgcagggaaatcacggatctcagttgctggccctggcctcgccgcgtcattgatgggcaaccaactggaccgcatcacccacctcaactacagcgagttgcccactggggacccatctgggattgagaaggacgagctgcgagtcggggttgcctacttcttctcggatgaggaggaggacctggacgaacgcgggcagccggacaagtttggtgtgaagggccccccaggttgcagcccttgcccagagagccccagccgccaccaccaccacctgctgcaccagctcgtcctcaacgagactcagttctccgccttccggggccaggaatgcatcttttccaaagtgaccggcggccctcagggcgccgacttgagtgtctacgcggtcactgcgctgccggcgatctgcgagccaggcgacctgctagagctcttgtggctacagccggcgaccgagcagcccgcgccagcccctcactgggccgtctacgtgggcggcgggcagatcatccacctgcaccaaggcgagatccgccaggacagcctgtaccaggcgggcgcggccaacgtgggccgggtggtgaatagctggtaccgctaccgcccgctggtggccgagctagtggtgcagaacgcctgtggccacctgggcctcaagagcgaggagatctgctggacgaactccgagagcttcgctgcctggtgccgctttggaaagcgcgagttcaaggctggcggggaggtccccgcaggaacgcagccgccgcaacagcagtattatctcaaagtgcatctggaggagaacaaagtccacacggcccggttccacagcctggaggacctcatccgcgagaagcgtcgcatagacgccagtggccgcctgcgagtgctgcaggagcttgaggactttgtggacgacaaggagtagcctcagaggggcagctcggcgtgccagttcccacgcccggagttccctttcggtccccgcagttctgcaccccatgttcccctaacgcgcccgcccagggccagcggctggaagcttcgggaactcaccaccacccaccgcactgggcgggagcagctgcgcgctcctaagacaaccctggtgttggtgatcatgccagggtaatccagcctgcgcctctgccctgggttgtgaagggaaagagggagtgggcaaaaggggagcaaggacactacctttccagggagccaagggtcagtgactcttctgcagacagggcaaatatccttagtcacagggaaccgtcacccaccacccccagatgtgcacacacaaaccagtcggaggtgagagttggtcttttcaggacacaattcaactcccgaatggagagtggatgtgcccccggatatcagaattcccatgaaaccgagcctgtctctgtactttggagcacttcagggactccaggttaccctgaggctgcctggaactgtcttgcagctctccagcccagagtctcctgacaaagcattccaggctgagctagataggattgacttctcagtttgagcaactggaagccgatgccattcccggcttgaccgacacttgccagaaggaaagccttctgggtcccgggaggaaaatggttgaagcacctttttgggagaggagggcctgctggctccggaaaaggagctaattcacctggcctgtgggcacttgaacttaggaaggaggaggctttttgctcggaagcccttgattgcttcccttctcactcagagtcctgtattcagcgggactgaaggagagggaggcagggaagatctacaacattccagaaaccagcattaggacagcctagccagtgtctttagtttggcttttcctaactagaaggcaggaggcaggaggcaggtggagattgtttgtaaaatgaaacagcagttttccaacgatatcaacaaagcctacagtgtcgatgcttctcttgatcatttttagtaacatgctaatgaaatttcaaattgaaatttttattttcatggctttaatccatgatagcttaaatactgggggccattaggagtggaatttagctaagaccttagctgacattgctttcactctggtttttctcaactcttatgagaattctgtttggggatattataattattccttttttttttttttttcctggctttacaaagtaggcctgcaatggtggagctgtttattagtgtgtatattgtactgaattttttcagttcaagggtctgctgctttggtgaaaattgctagcaagttccatgagggttcttttcttcattctgtttaccatcatcatctcatctttgcattcccccctctcctcacctcttgatcccccttgaaaggaatttagagttcatgggctttggggcccgcttttgtagcttgtcctgatgtttatttctgagaacagggaagcgctcttagaagcaggacagaatgtgtgtctttctaaacatgaaggttatgtgacgctcctttctttgggcaagagtttgtggatttttctccaaggggtacaaccccagcctaactgatcgttacttgattctttgtgttacacacaccttggaaggtgcacagtctctcatgagggagtttgtcaaataatgatgtttagctcatggttgcaagcaattggatactatggtttcattgaacagcaaacactatgtccaaagccactttcttggcatttcaaaactaatgcaataaaaactagtagaagttagcaggcagggaaatgccatttccatggtaaatggtttgtttctgttttctggggatttttgttgttttattttgtttcattttgttctcatgctggattcattctctgatcttgagtcaaaaggtcaaatcaatgaaatatgaactaaagtatttttctgaagccaatcgagtgatttattttttaaaactgcttatgttttttctttcagcacatacaacagcaaaacttttgtaaacttaacctttgcatgtatggagaactgaaagtcatttatttctctaacttagtcttttggcaaatgacagattgatgaccataaaccgaattctttcttgtgtctacacacaccatatcctttcctgtgtcctactactgtatcttggctccctgctgaattaaataccatcctaagcaaaaaaaaaaaaaaaaaaaaaaa

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