LOCUS       NM_020565               1096 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus sulfotransferase family 3A, member 1 (Sult3a1), mRNA.
ACCESSION   NM_020565 XM_993130
VERSION     NM_020565.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1096)
  AUTHORS   Senggunprai,L., Yoshinari,K. and Yamazoe,Y.
  TITLE     Inhibitory effects of kynurenic acid, a tryptophan metabolite, and
            its derivatives on cytosolic sulfotransferases
  JOURNAL   Biochem J 422 (3), 455-462 (2009)
   PUBMED   19548878
  REMARK    Erratum:[Biochem J. 2009 Nov 1;423(3):442]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1096)
  AUTHORS   Takahashi,S., Sakakibara,Y., Mishiro,E., Kouriki,H., Nobe,R.,
            Kurogi,K., Yasuda,S., Liu,M.C. and Suiko,M.
  TITLE     Molecular cloning, expression, and characterization of mouse amine
            N-sulfotransferases
  JOURNAL   Biochem Biophys Res Commun 375 (4), 531-535 (2008)
   PUBMED   18725199
  REMARK    GeneRIF: These results imply that these two amine-sulfonating
            SULT3s may play essential roles in the metabolism and
            detoxification of aromatic amine compounds in the body.
REFERENCE   3  (bases 1 to 1096)
  AUTHORS   Freimuth,R.R., Wiepert,M., Chute,C.G., Wieben,E.D. and
            Weinshilboum,R.M.
  TITLE     Human cytosolic sulfotransferase database mining: identification of
            seven novel genes and pseudogenes
  JOURNAL   Pharmacogenomics J 4 (1), 54-65 (2004)
   PUBMED   14676822
REFERENCE   4  (bases 1 to 1096)
  AUTHORS   Sakakibara,Y., Yanagisawa,K., Takami,Y., Nakayama,T., Suiko,M. and
            Liu,M.C.
  TITLE     Molecular cloning, expression, and functional characterization of
            novel mouse sulfotransferases
  JOURNAL   Biochem Biophys Res Commun 247 (3), 681-686 (1998)
   PUBMED   9647753
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC125595.1.
            
            On Apr 2, 2008 this sequence version replaced NM_020565.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC125593.1, AF026075.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1096
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 18.82 cM"
     gene            1..1096
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /note="sulfotransferase family 3A, member 1"
                     /db_xref="GeneID:57430"
                     /db_xref="MGI:MGI:1931469"
     exon            1..51
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /inference="alignment:Splign:2.1.0"
     exon            52..203
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    53..55
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /note="upstream in-frame stop codon"
     CDS             62..943
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /EC_number="2.8.2.3"
                     /note="sulfotransferase-related protein SULT-X2;
                     sulfotransferase related gene X2; sulfotransferase 3A1"
                     /codon_start=1
                     /product="amine sulfotransferase"
                     /protein_id="NP_065590.2"
                     /db_xref="CCDS:CCDS23771.1"
                     /db_xref="GeneID:57430"
                     /db_xref="MGI:MGI:1931469"
                     /translation="

MDNKDEYLLNFKGYNFQKTLVKMEVVENIENYEIRDDDIFIVTYPKSGTIWTQQILSLIYFEGHRNRTENIETIDRAPFFEYNIHKLDYAKMPSPRIFSSHIPYYLVPKGLKDKKAKILYIYRNPKDVLISYFHFSNLMLIFQNPDTVESFMQTFLDGDVVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDLRSSVLKICSFLEKELSEEDVDAVVRQATFQKMKADPRANYEHIIKDELGTRNEMGSFLRKGVVGDWKHYLTVDQSERFDKIFHRNMKNIPLKFIWDINEE"

     misc_feature    167..901
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /note="Sulfotransferase domain; Region: Sulfotransfer_1;
                     pfam00685"
                     /db_xref="CDD:425820"
     exon            204..412
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /inference="alignment:Splign:2.1.0"
     exon            413..539
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /inference="alignment:Splign:2.1.0"
     exon            540..634
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /inference="alignment:Splign:2.1.0"
     exon            635..821
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /inference="alignment:Splign:2.1.0"
     exon            822..1096
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      962..967
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /note="hexamer: AATAAA"
     polyA_site      989
                     /gene="Sult3a1"
                     /gene_synonym="ST3A1; Sult-x2; Sultx2"
                     /note="major polyA site"
ORIGIN      

tcaggctgctggtgtaagcactatccagtttctttttgaagggcactagaggtaacaaattatggacaataaagatgaatatttgcttaacttcaaaggctataattttcagaaaactttagttaaaatggaagtagtggaaaatatagaaaattatgaaattcgagatgatgacatcttcattgtcacatatccaaagtctggtaccatctggacccagcagatcctttccttgatttattttgagggtcatcggaacagaactgaaaacatcgaaacaatagatagagcaccattttttgagtacaatattcacaaattagactatgccaaaatgccatcacctcgcatcttcagttcccacattccatattacttagtaccaaaaggtctcaaggacaaaaaagccaaaattctttatatctacagaaatcctaaagatgttttgatctcctattttcatttctcaaatttgatgcttatatttcaaaatccagacactgtagaaagttttatgcaaacatttctagatggagatgtggtaggaagcctttggtttgaccacataagaggctggtatgaacacagacatgatttcaatattatgttcatgagctttgaagacatgaagaaggacctcagaagctcagtgcttaaaatctgcagttttctggagaaagaactgagtgaagaagatgtggatgctgttgtgagacaagctacctttcagaaaatgaaagctgacccaagagcaaactatgaacacattataaaagatgaactcggaacaagaaatgagatgggaagtttccttcgcaaaggtgttgttggagactggaaacattatttgactgtggatcagagtgaaagatttgacaagatatttcacagaaacatgaaaaacatccccttaaaattcatctgggacataaatgaggagtagaatattaatcaccacgtgaataaaccatatgaaaatgtactagccagaggttgtactttaatattaaaattaatatatttgtctcatttaactattagttataaaacataattcacagacaaaatgattaccttgtgcctagattgttttcca

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