LOCUS       NM_001378274             857 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus claudin 34C2 (Cldn34c2), mRNA.
ACCESSION   NM_001378274 NM_001378243 XM_006528427
VERSION     NM_001378274.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Seker M, Fernandez-Rodriguez C, Martinez-Cruz LA and Muller D.
  TITLE     Mouse Models of Human Claudin-Associated Disorders: Benefits and
            Limitations
  JOURNAL   Int J Mol Sci 20 (21), 5504 (2019)
   PUBMED   31694170
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  AUTHORS   Baltzegar DA, Reading BJ, Brune ES and Borski RJ.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
REFERENCE   3  (bases 1 to 857)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   4  (bases 1 to 857)
  AUTHORS   Lal-Nag M and Morin PJ.
  TITLE     The claudins
  JOURNAL   Genome Biol 10 (8), 235 (2009)
   PUBMED   19706201
  REMARK    Review article
REFERENCE   5  (bases 1 to 857)
  AUTHORS   Van Itallie CM and Anderson JM.
  TITLE     Claudins and epithelial paracellular transport
  JOURNAL   Annu Rev Physiol 68, 403-429 (2006)
   PUBMED   16460278
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX649235.2.
            
            On Feb 6, 2020 this sequence version replaced NM_001378243.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               BX649235.2         52121-52237
            118-158             BX649235.2         57535-57575
            159-857             BX649235.2         77309-78007
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 49.81 cM"
     gene            1..857
                     /gene="Cldn34c2"
                     /gene_synonym="EG625591; Gm6604"
                     /note="claudin 34C2"
                     /db_xref="GeneID:625591"
                     /db_xref="MGI:MGI:3644765"
     exon            1..117
                     /gene="Cldn34c2"
                     /gene_synonym="EG625591; Gm6604"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    91..93
                     /gene="Cldn34c2"
                     /gene_synonym="EG625591; Gm6604"
                     /note="upstream in-frame stop codon"
     misc_feature    115..117
                     /gene="Cldn34c2"
                     /gene_synonym="EG625591; Gm6604"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     MFISKRAARNRTLAGFHIFDAS"
     exon            118..158
                     /gene="Cldn34c2"
                     /gene_synonym="EG625591; Gm6604"
                     /inference="alignment:Splign:2.1.0"
     exon            159..857
                     /gene="Cldn34c2"
                     /gene_synonym="EG625591; Gm6604"
                     /inference="alignment:Splign:2.1.0"
     CDS             181..819
                     /gene="Cldn34c2"
                     /gene_synonym="EG625591; Gm6604"
                     /codon_start=1
                     /product="claudin 34C2"
                     /protein_id="NP_001365203.1"
                     /db_xref="GeneID:625591"
                     /db_xref="MGI:MGI:3644765"
                     /translation="

MVLLNKSANHQIRGFTLATIACIMCNTSMALPEWRICYLNNSMLSYPSLAFVNIWEAYICHHNHNSSHLRDCHYYTCHNNLVPLDIRVSQILLLVANVVGLVGTVCSVFALQQLYTEELHKNNDYNPFVLSAVLNAIASTFIFLAVMCNHLSVPSKEEVSFLQSFQMPIFSNAQRAGRAMGLAYISAILFLLSAIIFISYCPSMEIKMFPRV"

ORIGIN      

gaatggaatactactcagctactaaaaacaaggacatcttgaaatttgcagtcagatgcatggaacgagaaaaggtcatcctgagtgatgtaaaccagatccagaaatacaaacatgtttatcagcaagagagctgcaagaaataggacccttgctggtttccacatatttgatgccagcatggtcctgctaaacaagtctgccaatcaccaaataagaggtttcactttagctacaatagcatgcataatgtgcaatacctctatggcccttccagaatggcgaatttgctacttgaacaactccatgctttcctacccaagtctggcttttgtgaatatttgggaggcctacatctgccaccacaaccacaactcaagccacctgagagattgccattactacacctgccataacaaccttgttcctttggatatccgggtatctcaaattctgctcctggttgcaaatgttgttggtctggttgggacagtttgttctgtctttgctctacagcagttatacacagaggaactgcataagaataatgactacaatccatttgttctttcagctgtcctcaatgctattgctagcacctttatttttcttgctgttatgtgtaatcacctctccgtgcccagcaaggaagaggtatctttcctgcaatctttccaaatgccaattttttccaatgctcaaagagcaggcagagccatgggattggcatacatatctgccatattgtttttattaagtgctataatttttatttcttactgtccttcaatggaaatcaaaatgtttccccgtgtctgaaaataaatttgcagcatacataaccttgaaaatcaaaa

//