LOCUS       NM_001159275            1346 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus solute carrier family 25 (mitochondrial carrier,
            ornithine transporter) member 2 (Slc25a2), mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001159275 XM_111757 XM_909128
VERSION     NM_001159275.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Oyama Y, Miyata H, Shimada K, Fujihara Y, Tokuhiro K, Garcia TX,
            Matzuk MM and Ikawa M.
  TITLE     CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched
            genes dispensable for male fertility in mice
  JOURNAL   Asian J Androl 24 (3), 266-272 (2022)
   PUBMED   34290169
REFERENCE   2  (bases 1 to 1346)
  AUTHORS   Garg,A., O'Rourke,J., Long,C., Doering,J., Ravenscroft,G.,
            Bezprozvannaya,S., Nelson,B.R., Beetz,N., Li,L., Chen,S.,
            Laing,N.G., Grange,R.W., Bassel-Duby,R. and Olson,E.N.
  TITLE     KLHL40 deficiency destabilizes thin filament proteins and promotes
            nemaline myopathy
  JOURNAL   J Clin Invest 124 (8), 3529-3539 (2014)
   PUBMED   24960163
REFERENCE   3  (bases 1 to 1346)
  AUTHORS   Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M,
            Noonan JP, Zhang MQ, Myers RM and Maniatis T.
  TITLE     Comparative DNA sequence analysis of mouse and human protocadherin
            gene clusters
  JOURNAL   Genome Res 11 (3), 389-404 (2001)
   PUBMED   11230163
REFERENCE   4  (bases 1 to 1346)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     Large exons encoding multiple ectodomains are a characteristic
            feature of protocadherin genes
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3124-3129 (2000)
   PUBMED   10716726
REFERENCE   5  (bases 1 to 1346)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     A striking organization of a large family of human neural
            cadherin-like cell adhesion genes
  JOURNAL   Cell 97 (6), 779-790 (1999)
   PUBMED   10380929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077159.1.
            
            On or before Apr 11, 2009 this sequence version replaced
            XM_909128.3, XM_111757.7.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK077159.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1346              AK077159.1         2-1347
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.54 cM"
     gene            1..1346
                     /gene="Slc25a2"
                     /gene_synonym="Ornt2"
                     /note="solute carrier family 25 (mitochondrial carrier,
                     ornithine transporter) member 2"
                     /db_xref="GeneID:83885"
                     /db_xref="MGI:MGI:2137907"
     exon            1..1346
                     /gene="Slc25a2"
                     /gene_synonym="Ornt2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    40..42
                     /gene="Slc25a2"
                     /gene_synonym="Ornt2"
                     /note="upstream in-frame stop codon"
     CDS             250..1047
                     /gene="Slc25a2"
                     /gene_synonym="Ornt2"
                     /note="ornithine transporter 2; mitochondrial ornithine
                     transporter"
                     /codon_start=1
                     /product="mitochondrial ornithine transporter 2"
                     /protein_id="NP_001152747.1"
                     /db_xref="CCDS:CCDS50258.1"
                     /db_xref="GeneID:83885"
                     /db_xref="MGI:MGI:2137907"
                     /translation="

MQTFPQLYKGLADCFLKTYNQVGIRGLYRGTSPALLAYVTQGSVLFMCFGFCQQFVRKVARVEQNAELNDLETATAGSLASAFAALALCPTELVKCRLQTMYEMKMSGKIAQSYNTIWSMVKSIFMKDGPLGFYRGLSTTLAQEIPGYFFYFGGYEISRSFFASGGSKDELGPVPLMLSGGFAGICLWLIIFPVDCIKSRIQVLSMFGKPAGLIETFISVVRNEGISALYSGLKATLIRAIPSNAALFLVYEYSRKMMMNMVEEY"

     misc_feature    <250..423
                     /gene="Slc25a2"
                     /gene_synonym="Ornt2"
                     /note="Mitochondrial carrier protein; Region: Mito_carr;
                     pfam00153"
                     /db_xref="CDD:395101"
     misc_feature    <514..735
                     /gene="Slc25a2"
                     /gene_synonym="Ornt2"
                     /note="Mitochondrial carrier protein; Region: Mito_carr;
                     pfam00153"
                     /db_xref="CDD:395101"
     misc_feature    754..1032
                     /gene="Slc25a2"
                     /gene_synonym="Ornt2"
                     /note="Mitochondrial carrier protein; Region: Mito_carr;
                     pfam00153"
                     /db_xref="CDD:395101"
ORIGIN      

agcggccggagagtgcggcggcggcccaaggctttggtttgagtagccttgacaaggagacagagacacaggtccgcagcagctggccgtgggcgcaaaagagacttggcttctgacgacaccctcgggagggtggaggaacatgaagtccaccctgccatccaagccgccatagacctcactgcgggcgcagcagggggcggagcttgtgtgctgactgggcaacccttcgacaccataaaagtaaagatgcagacatttcctcagctgtacaaaggccttgccgactgcttcctgaaaacatacaaccaagtgggcatccgtggcctttacaggggaaccagtcctgcactgctagcctatgtcacccagggttctgtcctgttcatgtgctttggcttttgccaacagtttgtcaggaaagtggctagagtggagcagaatgcagagctgaacgacttggagactgctactgctgggtcgctggcttctgcatttgctgcgctggctctctgccccactgagcttgtgaagtgtcggctgcagaccatgtatgagatgaagatgtcagggaagatagcacaaagctataacacaatttggtctatggttaagagtatcttcatgaaggatggtcccttaggcttctatcgtggactctcgaccactcttgctcaggaaatacctggctatttcttctactttgggggctatgaaatcagtcgatcattttttgcatcagggggatcaaaggatgaactaggccctgtccctttgatgttaagtggaggctttgctgggatctgtctctggcttatcatattcccagtggactgcattaaatccagaatccaggttctttctatgtttgggaagcctgcaggattaatcgaaacctttataagtgttgtgagaaatgaagggatatcagccttgtattctggattgaaagccactctgattcgagccatcccttccaatgctgctctctttttggtttatgagtacagcagaaagatgatgatgaacatggtggaagaatactgaagtgtctattgatgagtccttgtctgagcacatgaatgagaggaccacagctctacatgtcaaagagttcaagaccaacatggagttagctttgactgggaatttcgggtttgtcttcccttcctcaaatctcataccttgtggagagatctttatatcatatggtttcttcctgcaatcctactgaaataggaaaatcactagttttgctggtggtgggatctacagggtgaacccaagactctatgtacttaatctcaattatcaaggcttcttcataaatctatatatgcatcttg

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