LOCUS       NM_001013760            1010 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus claudin 34B3 (Cldn34b3), mRNA.
ACCESSION   NM_001013760 XM_138829
VERSION     NM_001013760.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1010)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 1010)
  AUTHORS   Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
            Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
            B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
            Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
            GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
            Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
            Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
            SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
            Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
            Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
            Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
            Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
            Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
            Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
            Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL670100.11.
            
            On Aug 28, 2018 this sequence version replaced NM_001013760.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048515.1, BU937105.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               AL670100.11        74325-74463
            140-1010            AL670100.11        76822-77692
FEATURES             Location/Qualifiers
     source          1..1010
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 38.3 cM"
     gene            1..1010
                     /gene="Cldn34b3"
                     /gene_synonym="EG238829; Gm4937"
                     /note="claudin 34B3"
                     /db_xref="GeneID:238829"
                     /db_xref="MGI:MGI:3648293"
     exon            1..139
                     /gene="Cldn34b3"
                     /gene_synonym="EG238829; Gm4937"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    87..89
                     /gene="Cldn34b3"
                     /gene_synonym="EG238829; Gm4937"
                     /note="upstream in-frame stop codon"
     exon            140..1010
                     /gene="Cldn34b3"
                     /gene_synonym="EG238829; Gm4937"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..794
                     /gene="Cldn34b3"
                     /gene_synonym="EG238829; Gm4937"
                     /codon_start=1
                     /product="claudin 34B3 precursor"
                     /protein_id="NP_001013782.1"
                     /db_xref="CCDS:CCDS53115.1"
                     /db_xref="GeneID:238829"
                     /db_xref="MGI:MGI:3648293"
                     /translation="

MPLKKCHRQMGGFALTTVAWLLCCISTGLPQWQVWHYEDPVILKPTVALVGMWRACIFHTDSNSSNTRVCYQYKYDGSIHLYIQVNQHLLLVSSFLGLFGKITTIIALSNVHMGRVRRNATCNPFRLSGILNIIASSFLYLAVLFNYIAIMSKWGIAFPPSFNLPFQPDIRKMGSATALAIIAAVFFLLSGTICLSSNLAIGKVPHSKM"

     sig_peptide     165..254
                     /gene="Cldn34b3"
                     /gene_synonym="EG238829; Gm4937"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     misc_feature    216..752
                     /gene="Cldn34b3"
                     /gene_synonym="EG238829; Gm4937"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
ORIGIN      

acgctcagagctgatggtgaagccagcaaggagcctcaaagtcttagtgagaggaccaatttccttgtcatctctactgcctcagataactgactgccaagcaacatcatctacagttcacttgtgaattgtgtctctgttctcaagcattaactgtcatcatcatgccattgaaaaagtgccatcgccaaatgggaggttttgctttgaccactgtggcctggctactctgctgcatatccacaggcctccctcagtggcaagtgtggcactatgaagatcctgtgatcctcaagcctacagtggctttagtgggcatgtggagagcctgcattttccacacagacagcaactccagcaacaccagagtatgttaccaatacaaatacgatggctccattcatttatatattcaagtaaaccagcacttgctgctggtttctagctttcttggtctttttgggaaaatcaccaccattattgctctttcgaatgtgcatatgggaagagtacggaggaatgccacctgcaatccatttagactttcaggcatactgaacatcattgctagcagctttctttaccttgctgttttgttcaattacatagccatcatgagcaaatgggggattgccttcccaccatctttcaatttgcctttccagccagacattcggaagatgggaagtgccacggctttggcaattatagctgcagttttctttctactaagtggcacaatttgcctttcttcaaatttagccataggcaaggtgccccattccaaaatgtaaatctctaccttacatagccttgaaatgccaggaaagataatgagtattcttcacatgtctacacgaatttacaaagaacttgaaaggatgccaattgtggcctatgaccaaaaaatagtccggttgactttctcttatcttttttaacttctttcgtgtttccttaatgcattatttggcttgtgggcttctattaaataaaatcttattttatgg

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