LOCUS       XM_070514190            6272 bp    mRNA    linear   MAM 18-DEC-2024
DEFINITION  PREDICTED: Equus asinus NRDE-2, necessary for RNA interference,
            domain containing (NRDE2), transcript variant X2, mRNA.
ACCESSION   XM_070514190
VERSION     XM_070514190.1
DBLINK      BioProject: PRJNA1198117
KEYWORDS    RefSeq.
SOURCE      Equus asinus (ass)
  ORGANISM  Equus asinus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091796) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_041296235.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/16/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6272
                     /organism="Equus asinus"
                     /mol_type="mRNA"
                     /isolate="D_3611"
                     /db_xref="taxon:9793"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="Whole blood in anticoagulant"
                     /geo_loc_name="USA: Ithaca, New York"
                     /collection_date="2018-03-01"
                     /breed="Donkey"
     gene            1..6272
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 116 long SRA reads"
                     /db_xref="GeneID:106825367"
     CDS             624..3449
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X2"
                     /protein_id="XP_070370291.1"
                     /db_xref="GeneID:106825367"
                     /translation="

MKKNVGLMNIDGVAVSSQTAPPSSEPVSFIPVKDSDDAAPPVTAWLNPLGIYDQSTTQWLQGKGASEQESKQPDSQVDRESALLKAKVEEFNRRVREHPRDVQLWMAFVAFQDEVMKSPGLYAIEEGEQEKRKRSLKLLLEKKLAILERAIESNPSCVDLKLAKLQLCTELWEPATLLREWQKLIFLHPNNTALWHKYLLFCQSQFSTFSISKIHSLYGKCLSTLSAVKDGSILSHPELPGTEEAMFALFLQQCHFLRQAGHSEKAVSLFQAMVDFTFFKPDSVKGLPTKGQVEFFEPFWDSGEPRAGEKGARGWRAWMHQQERGGWVVISPDDEEEEPEDDDQEIRDNTLPRWQIWLAAERSRDQRHWRPWRPDKTKKQTEEDCEDPERQVLFDDIGQSLIRLSSQDLQFRLIAAFLQFLGVPCGVSPPASCLYLAMDENSIFDNGLCDEKPLTFLNLSFSGVSCVGRMDQLGCRRWTRAHGREGEDFIRNVFHLVLPLFSGKERSQLCLSWLQYEIAKVIWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENRNDFCLWKQYAHLEWLLGNMEDARKVFDTALSMAGSRELKDHELCELSLLYAELEVELLLDSRGAATARAVHILTRLTENGPCGPYAGQVLAVHILKARKAYEHALQDCLGEGCVSGLAPTNSLNCLTSLVKCFMLFQYLTVGIDATVRIYEQVFAKLKGSGSPEGCGQDDSAGTQRLSSVLEAVTLMHTSLLRFHMKVSVYPLAPLREALSEALKLYPGNQVLWRSYVQIQNKSHSASKTRRFFDAVTRSAKPLEPWLFAIEAEKMRKRLVETVQRVDGREVHATIPETGLTHRIKALFENAMRSDSGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKVLYMDAVEYFPDEMQEILDLMTEKELRVRLPLEELELLLED"

     polyA_site      6272
                     /gene="NRDE2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

accggcgcccgctcaccggcgccatttctgtggaggggaacggcggtgcggcctgtgatcatggcgctgttcccggcctttgcgggcgttagtgaagctcccgctagcggaagttctaggaaaggagtcctctgaaatcagagccatcagaggaaagtgacactaacagaaagctcaaatcaataagcagaaaaaagaagaaagagaaaaagaagaaaaggaagcatcagcatcataagaaaaccaagagaaaacatgggcagtcgagtagcagtggatctgagccagatactgattcggaaaaggacagatcttccagaagcatcagagacagtaaaagggaatcagagaaaccaaatcagcaaaataatgccactgctgatagtggacgtcgccttgtttggcttgaggacgttcaggctctgacaggagaaaccttcagaacagataagaagccggatcctgcaaactgggagtataagtctctctaccgtggagacatagcaaggtacaagaggaaaggagactcctgccttggcattaacccaaagaagcagtgtatatcttgggaggggacttccacgggaaagaagcatccacacaagcgtgttgaacgctattttatgaagaagaatgtgggattaatgaacattgacggagttgccgttagcagtcaaactgcacctccctcgtctgagcccgtctcatttatcccagtgaaggactcagatgatgcggctcctcctgttacagcctggttgaaccctctggggatttatgatcagtccaccacacagtggttacaaggaaagggtgcttcagagcaagaatcaaagcagccagactcacaggtggacagagagagcgcgctgctcaaggccaaggtggaggagtttaacaggagggtccgggagcatcctcgggatgttcagctgtggatggcgtttgttgcttttcaggacgaggtcatgaaaagtccgggcctgtatgccatcgaggaaggagagcaggaaaagcgaaagaggtccctgaagctgcttctggagaagaagctggccatcctggagcgggccattgaaagcaacccgagctgcgtggacctgaagctcgccaagctgcagctctgcacggagctctgggagcccgccaccctgctcagggagtggcagaaactcatattcttacatcccaacaatacagccctttggcataaatatcttttattttgccagagccagtttagcaccttttcaatatcaaaaattcacagtctttatggaaagtgcttgagtaccctgtctgctgttaaggatggcagcatcttgtctcaccctgagttgcccggcaccgaggaggccatgtttgccctctttcttcagcagtgccactttctgcggcaggccggtcactctgagaaggccgtctctctgttccaggccatggtcgacttcaccttcttcaaaccggacagtgtgaaagggctgcctaccaaaggccaggtggagttctttgagcccttttgggacagtggagagccccgggctggggagaagggcgcccggggctggagagcgtggatgcaccagcaggagcggggtggctgggtggtcatcagtccagatgatgaggaggaggaaccagaagatgatgatcaggaaataagagataacactctgcccaggtggcagatctggcttgctgctgagcggtcccgagaccagaggcactggcggccgtggcgcccagataagaccaagaagcagactgaggaagactgtgaggatccagagagacaggtgttgtttgatgatattggacaatctctgatccgactttccagccaggatcttcagtttcggctgattgcggccttcctgcagttcttgggcgtgccttgtggcgtcagccctcccgcctcctgcctttatctggccatggacgagaacagcatctttgataacggactttgtgatgaaaagccgttgactttcctcaacctgtcattttctggcgtcagctgtgttggccgcatggaccagttgggctgccggcgctggaccagagctcacggtcgagagggcgaggacttcatccgcaacgtcttccacctggtgctgcctttgttttccggcaaggagaggtctcagctctgcctctcctggttacagtacgagattgcaaaggtcatctggtgtctgcacactaaaaacaagaagagattaaagtcacaaggaaagaactgcaaaaagctagccaagaatctccttaaggagccggaaaaccgcaacgatttttgcctctggaagcagtatgcgcatctggagtggttgcttggcaacatggaggacgccaggaaggttttcgatacagcactcagcatggcagggagcagagaactgaaggatcacgaactctgtgagctcagtctgctctacgctgagctggaggtggagctgttgctagactcgagaggggccgccacagcccgagctgttcacatcttaaccaggctgactgagaatgggccctgtgggccctatgccgggcaggtcttggccgttcacattttgaaagctcggaaggcttatgaacacgcactgcaggactgcttgggtgagggctgtgtctctggactggctcccaccaactccttgaactgcctaactagcttggtcaaatgctttatgctctttcagtatttgaccgtggggatcgatgccactgtgcggatatacgagcaagtatttgcaaaactgaagggctctggttccccagaaggctgtggccaggatgacagtgccggcacccagcgtctgagcagtgttctcgaggctgtcacactgatgcacaccagcctgctcagattccacatgaaagtcagcgtttacccgctggcccctctgcgagaggcactctccgaggctttaaagttgtatccgggcaaccaggttctttggaggtcatatgtacagattcagaataagtctcacagtgccagtaagaccagaagattctttgatgcagtcaccaggtctgctaaacccttagagccttggttgtttgccattgaagccgagaaaatgaggaagagactagtggaaactgttcagagggtagatggtagagaggtccacgccacaattcctgagaccggcttgacacatcggatcaaagccctgtttgaaaatgcaatgcggagtgacagcggcagccagtgccccttactgtggaggatgtatttgaattttttggtttccttaggaaacaaggaaagaagcaaaggtgtgttctacaaagcacttcagaattgtccttgggcaaaggtgttgtacatggacgctgtggagtacttccccgatgagatgcaggagatcctggacctgatgactgagaaggagctccgggtgcgcctgccgctggaggagctggagcttctgcttgaggactagagaccaggaagggaatggggaccacatctctgaggcaacgttgcctgccctgtcggagccagggtgggcaagaggagaccagtgatgcacatgtgcaagcgtgtgttaacagacttttgctttagaagtttctcttgagaatgtctgggttaccagtctctcacctcttgcatattttttgcatgtgcaaatgacacaaaagctattgttttacatattatatatgtgcacatgtgtatatatgtctgtagacaagaatcacgctaagtgattacaaaacctactgtggttggtgtgtgcaagttctcgttcctttggctttcttagcccagccggtgccagcccccaccatggtgagtgtaccccctcagttggcatccttggtggtcctgccaagtcttatgggtcttgcagcctttgatatgaaaggtctggttactcaacactaggatctcctcccctgggcaggttagcaggagagcagatcttgcccttatcttcagagcagtgggaagtcatttaaaacttggtgttctggcctctatcaagtgtattaagagtttctcattattccctcagccctactctgtgacacttccatctgtggaccagcagcatcacctgggagcttgttagaaatgcagactctcaggccccttcctagcactgctgagtcagaatctgcatccgaacaggccttcctggggacttgtgtgcacactggtgtggaaggcactgcccaaagacataaggcctctgctgcaggggagggagcctgccagtgacctctgtctcagaggagagtggaatggagccagctccttccgaccaaacccagccctgcctgtgagatgtgcggaaggtacgccctcctctgctatgcatccgcactgcttaagatacgaaggcccagactggccatgttattttgatttctgaggggttcccagcttctctggctttttaaaaaaagtcatgatcttgagaattgctgaagacatatttccttggcacctcatccagaaaagccagtgttgcagaatagttttggctagaaactgacggacattggttgggaaggcaacatagagcactttctggggcagcgtctcagagcccccaaggaagttgccagccaaccatgtggatgcttaccttgctataccctgaactgctcagaaaggaaagagcagtgcaggaaacagacaaagaaaaggaaggggaaactgacacatttccaaacgctcttgagagagatgaggtttctgaatccgacaacaggcagggctggtatgggattcttcagccctgaccttttgagatttttaaggaaccctcaatctcttcgcaacatcagtacttccttcctggccccacagtgctgagaacccacagaacttccataagggaaagctgtcttttcttcctttgaagccacagccacatgaactcagactttgttgcttaaacaagaaagatcgctggctatgtggttaggatcatttctttcccattagctgctgttgtacagtaactccaccaccagctctgggggcaacaggtactgaagtctgcactccatgtaatcactcacagaagcttccctaacacctggatccacccacttggtgctgctgagcagcaggtgtggagacaccagaaagaagatgaactgttagagaaagagcacgctttattgggcagagagcactgcacgtgaccaacagacgaaggcagcccggtgggcatcctacacttatgctcaaaaacatacaggggatgttttgctaataaagaccaactggaacacggactcctggggcagcttccccagcctcatccctctgaggcgctgggagcccccactgccatttccttgaaggcacctgtggtccactagagatacagcccctcaggggtgccttcctgcttcttataaaggacattttctttagattttttgaagtcttcatttgttactttcattctgcgttctctcaaggccatcagaccagcttctgtacagattgcctgtaagacagaacagtatgttcagaaagtgaaacactttatttttattctaacaattaaaagagccattttgaaataaggtgtaagacacttagactaaacacacactgctcaaatcatttgggaaagattagatttcttaaatgttgtaagcattctaattattttctcaaaggatctgaggtggcttaaactgggagtgattaacaaagaggaggactggcccaggaatcggtgctccaggttctagtactggctcagcttctaacagctgtgtggcctggcaggtcagtaagttctcacagccccactttcgttaaagggagtcatactcctagaaaacagatgaaattatacccggcctggaaatctagaggcaacagagattatacctccatttcatttacccatactcagaacatgtattctagttaaagaagtttcagtatagtatttatggtaatatgtttattttctcaataattacttgccaaaagtagaacaaaacaagaacctatgtaatacaatgtgacaaaaacacagttaatcctggcactgaagtttctatttggttctggccctcaggatattcaagatggttcagtagaaaagagaaaccaaataggcaaaagggtgacatttggtaaactgaggtgatgggcctacgggtgtttactactgttgcagcttttctgaaggcttgaaatttttcaaaataaaaagttggtgcaaaattcaaaaataatttcaattttaaaaagagttttactcacgaactaagatactcatcta

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