LOCUS       XM_068115545            4069 bp    mRNA    linear   VRT 04-SEP-2024
DEFINITION  PREDICTED: Myxine glutinosa NRDE-2, necessary for RNA interference,
            domain containing (NRDE2), transcript variant X1, mRNA.
ACCESSION   XM_068115545
VERSION     XM_068115545.1
DBLINK      BioProject: PRJNA1152620
KEYWORDS    RefSeq.
SOURCE      Myxine glutinosa (Atlantic hagfish)
  ORGANISM  Myxine glutinosa
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
            Myxini; Myxiniformes; Myxinidae; Myxininae; Myxine.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_090426) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_040869285.1-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Myxine glutinosa"
                     /mol_type="mRNA"
                     /isolate="MG_SS"
                     /isolation_source="wild captured"
                     /db_xref="taxon:7769"
                     /chromosome="5"
                     /sex="hermaphrodite"
                     /tissue_type="testes"
                     /dev_stage="adult"
                     /geo_loc_name="USA: Atlantic Ocean, Gulf of Maine"
                     /collection_date="2011-10"
     gene            1..4069
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins"
                     /db_xref="GeneID:137426728"
     CDS             236..3775
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X1"
                     /protein_id="XP_067971646.1"
                     /db_xref="GeneID:137426728"
                     /translation="

MEASGSLFPAFGFAVAAASTKPPAADFDWLRNQSFATKDSLILERSQRSEDNERSSELDIGSRSDESDHSALNQHRHEKGKDVSQEWTKKKKKKKKKKKKTNKELRKRQREENEDVGSSEEEEHCGHRKQGNTTEASLVPPEGAVRSMWLEETDPELGLCYVDRKPDSANLQFMSIYRGHIARYQRLGDSCLGLDHKRQQLLWNTSKSRKKRWKKLLLGSNERYFSAGVLPVPREVVRAKLGLSLLREFLPVEMGSDCAMSGNSVAKLDARDLYTSATALYLQGKGHGSGGGPEERKPVKKLTTKNLVAEKLQARAEEFNRQLREDPHDVARWLAFIRFQDEAALQEDEASVYDGSEGRKKTRSALLERRLAIVERALEANPSSTELKLSRLEAGAELWTSSHLAGEWKNLVFMYPNDASLWARYLMFAQSHQSTFSVSRVNSLYSKCLRTLASAVDGSLLSHPALPGTTESMFGIFLQQCHFLRQTGHAEKCVSLFQAAIDFNFFRPDNLNDVKTHGLVDFFETFWDSGEPHFGEKGARGWSAWMRQQEGGGWVSLDQKGVRANEGDEASEGMDEEEELGYRGDEREPRWQVWLRLEKSRERRHCIPWCPDVGKGKKEEDCDDPDRQVLYDDIGKSLFTLETKELRFRLVCAFLSFLGISTCSSRDLAASALDDPIVIFSRDDKGLLTEASMLMGTGRLDFVCDMSDAVGGTWAGVEGRRSQHAEDFIRGVLEQAIQLFTGDEQAAIALAWMQHERLKVELSQRASAQRRSRVLGKRARRLAKTLLKQPAHRNRLPLWLEMAKLEWVLQDFGSARRILDTALGAALKASSAATNELCALCLWYAKMELASGPPAEAFNRTVHILTAVVAEKGMAYMPSSGQTNPPLAVLKSRKAYERALEVALTCVEVAPVDVCDSVWHHPSSYVLLVSCFAFLQYASMGPLAADTLFESACEQLQKLLGASMAKEKPTGRVARDLEVLAEERAVLLRYHGVTELTSPRRLLRKALSCAATAFPSNAHLLRLYVQSETEGPGLGMGSLRRAFSEMTRRSDSIMPWLFSLYAEMERKRVVENGLGISLHPETGLQHRIQALFERALEKPSASACPLLWRFYLYFAAMRGQSEKAIGIFYRAVQACPWVKVLYLDAVRLFPERLQEMVDLLTEKELRVRLPLEELDILLE"

     misc_feature    716..994
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(716..736,743..748,758..763,767..769,773..817,
                     824..832,836..844,863..871,896..901,905..910,917..937,
                     962..973,974..994)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1187..2212
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
     polyA_site      4069
                     /gene="NRDE2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

gtacactaaatgaagaagaagaataatacggaaggagaaacttgatcgtttggtctcgtccggttattttttctttcttttttctcgctggtctctctcggcgatgttgataactctcatgggccgcagtgacgtgattactccgcggtgacgacgatcgccaaacgtgatctcggccatcgggaacgcgaggtggcggtcccaggaaggacgcggtctcgaaggagacaccaccatggaggcttcagggtctctgttcccagccttcggtttcgctgttgctgcggcctccacgaagcctccggctgcagatttcgactggttgagaaatcaaagctttgcgaccaaagattctttgattttggaaagaagccaaagatctgaagataatgaaagatcatctgagcttgacataggctcaagaagtgatgagagtgatcattcggcattgaatcagcaccgtcatgaaaaggggaaggacgtatcacaagaatggacgaagaagaaaaaaaagaagaagaaaaaaaagaaaaagacgaataaggagttgagaaaacggcaacgagaagagaatgaggacgtaggttcttcagaagaggaagagcactgtgggcacaggaaacaaggaaacacaaccgaagcttctttggttccaccagaaggtgcggtccgttcaatgtggctggaagaaactgatcctgagttgggtctgtgttatgtggatcgcaagcctgactcggccaacttgcagtttatgtccatctatcgtggtcacatagccaggtaccagagattgggtgactcctgcttgggtctggaccacaaacgacagcagctgctctggaatacatcgaagtcaagaaagaaacgatggaaaaagttgctattggggtcgaatgagcgatatttctctgccggtgtccttccggtacctagagaggtggtccgggccaagttaggcctgtcccttctacgggagtttctccctgtggagatgggaagtgattgtgccatgtctggaaattcagttgcaaagctggatgcacgtgacctttacacctcggctacggcgctttatttacaaggaaagggtcacggtagcggaggaggacctgaggaaaggaagcctgttaagaaattgacgacaaagaaccttgttgcggaaaaactccaagcacgtgccgaggaattcaatcgccaattacgagaagatccgcatgatgtggcaaggtggctggctttcattcgctttcaggacgaagctgccctgcaggaagatgaagcctcggtttatgacggctcggagggacgaaagaagactcgctcagcacttctggaacggcgcttggccattgtggaacgggccttggaggcaaatcccagcagcacggagctgaaactgagtcgtcttgaagcaggggctgagctttggacttcgagccaccttgctggggagtggaagaacctggttttcatgtatccaaacgacgcttccctttgggctcgttatcttatgtttgcacagagccaccagtccaccttctcggtgtctcgcgtgaactcgctgtacagcaagtgcctgagaacgttggcatcagcggtcgatggttctctgctttcccaccctgcccttcctggcactactgaaagcatgtttggtatcttcctgcaacagtgccatttcttacggcaaactggtcatgctgagaagtgtgtttccctcttccaggctgctattgacttcaatttcttccgccctgacaacctaaatgatgtcaagacgcatggccttgtggatttctttgagacattttgggacagtggggaaccacacttcggtgagaagggagctcgaggctggagcgcctggatgcggcagcaggagggaggcgggtgggtgtcgctggaccagaaaggtgtgcgagcaaatgagggagatgaagcgagcgagggaatggatgaagaggaggaattggggtatcgaggagatgaacgtgaaccccgctggcaggtgtggctgaggcttgagaaatcccgtgagaggcggcactgcattccatggtgcccggatgttggcaaagggaaaaaggaagaggactgtgatgaccctgatcgccaggtcttgtatgatgacatcggaaagtcacttttcaccttggaaaccaaagagcttcgtttccgcctcgtctgtgccttcctgtctttccttggcatctcgacttgttcctctcgtgaccttgcagcctctgctctcgatgaccccatcgtcatctttagccgagatgacaaaggcttgctgactgaggcctccatgctgatgggcacaggacggctggattttgtttgtgacatgagcgatgcagttggaggaacatgggctggtgttgaaggccggaggagccaacatgcggaggacttcatacgtggtgtgttggagcaagccatacagctgttcacgggtgatgagcaggccgccattgctttggcctggatgcagcacgagagattaaaggttgagctgtcccaacgagcgtctgcacagcgccgttctcgtgtcctgggaaaacgtgctcgccgccttgccaagactctcctcaaacaaccggctcaccgcaatcgccttccgttatggctggaaatggccaagttggagtgggtgctgcaggactttggctcagcacgtcggatacttgatacagcacttggtgctgccctcaaggccagtagtgcagcaacaaatgagttgtgcgctctgtgtctgtggtacgccaagatggagctggcctcaggaccgccagctgaagccttcaatcggacagttcacatcctaactgccgttgtagcggaaaagggaatggcctacatgccatcgtcagggcagacaaatcctccgcttgcggtgctcaaatcacgcaaggcctacgagcgagcattggaagtggcattaacatgtgtggaggtggctcctgtggatgtatgtgacagtgtttggcatcaccctagttcttatgtcctacttgtgtcttgctttgcattcttgcaatatgcatcaatgggacccctggcagcagataccctatttgaaagcgcatgcgagcaactccagaaacttttgggtgccagcatggcgaaagagaagcccacggggcgagtagctcgtgacttggaagtcctggctgaagagagagcagtgttgctccgttatcatggcgtcacggaattgacatccccacgtaggctcctacgtaaggcgttgagttgcgcagcaacggcatttccttccaatgcacatctcctacggctgtacgtacagtcagagacagagggtcctgggcttggcatgggctcactgcggcgcgcattctctgagatgacacgtcgttctgacagcataatgccatggttgttctccttgtatgccgagatggagcgcaaacgggtggtggaaaatggtctgggcatctcgctccatcccgagaccggtctgcaacaccggatacaagctctgtttgaacgtgctcttgagaagcctagcgcttcggcctgtcctctcctgtggagattctacctttactttgcagcgatgcgagggcagtcggaaaaggctatcgggatcttctaccgtgctgtgcaggcctgcccttgggtcaaggtgctgtacttggatgctgtgcggttgtttccggagcgacttcaggaaatggttgacctcctcactgaaaaagagcttcgtgtacgtcttcctctggaggaattggacattttgttggaatgataactattagcaggccttgatggaagaagtttgatgctgtgaagcagcaaatgtttgcttcattcgtttgtgcggtatcatgggatctttggatgcggggagggtaatttttccgatgggtatccaaaatggaaggaccttctgtaccatttctcaccttttctttttaattaaaatgtcttatccccaaagcttcattgatccaaagaactgcaaatcggctgatcctggtatcgtcaaacatgaacaaggcttgttccttgtctgtacaataataaaatgcgcctatttgtt

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