LOCUS       XM_067242700            3825 bp    mRNA    linear   VRT 13-AUG-2024
DEFINITION  PREDICTED: Osmerus mordax NRDE-2, necessary for RNA interference,
            domain containing (nrde2), mRNA.
ACCESSION   XM_067242700
VERSION     XM_067242700.1
DBLINK      BioProject: PRJNA1145451
KEYWORDS    RefSeq.
SOURCE      Osmerus mordax (rainbow smelt)
  ORGANISM  Osmerus mordax
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Stomiati; Osmeriformes;
            Osmeridae; Osmerus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_090058) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_038355195.1-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/12/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3825
                     /organism="Osmerus mordax"
                     /mol_type="mRNA"
                     /isolate="fOsmMor3"
                     /db_xref="taxon:8014"
                     /chromosome="9"
                     /sex="male"
                     /tissue_type="muscle, testes, liver, kidney, brain, misc"
                     /dev_stage="adult"
                     /geo_loc_name="Canada: Placentia Bay Newfoundland"
                     /lat_lon="47.431645 N 53.826133 W"
                     /collection_date="2019-10-17"
                     /collected_by="Amber Messmer"
     gene            1..3825
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 Proteins"
                     /db_xref="GeneID:136948717"
     CDS             5..3613
                     /gene="nrde2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_067098801.1"
                     /db_xref="GeneID:136948717"
                     /translation="

MALFPAFAGLASTKVDEPHKELEWLTNQSFRSDEALSLHQRAVEKSIQLKQPAADTRLLSSEEEEEDRNDVSSKKRKKKEKKKKKKKHRRKRSGRPSDSSGSDSDTVYPSDLLKKDAEEPSQQPQVQCQLEGKFAWLDDLQSPPAQLFCLDRKADSANWQYKSLYRGDIARYRRKGQSCLGLDPRRQAISWAESESSNRKRSDKNRKQTERYFCSSARPLLKAPPVPSLPGAPAPGPTLEYIPLPLCPKEGGAGAGSGPVSWVNPLGVYDDSTSLWLQGRGHSEQGQGQEPSRDKDSSAALLAGRVEDFNRRLRETPTDTQLWLQFLHFQDELWDAGGFGGEGGSREAERGGRSLRASVEKKMSIAERALESNPGCVALQLERLRLSRELCEPAALQKEWRKLVFLHPNSAPIWREYLLFTQSHFSTFSVSKVNSAYGKCLSTLAAVQDGSMTSHPALPGTQESMLDIFVQQCHFLRQAGHSEKAACLFQALLDFTFFKPDSVKDLPTRQQVEFFEPFWDSGEARVGERGARGWKAWMLQQERGGWLLPNTDDDDDDDEDPEEELKDRTWPKGRIWLDIETSREANHWLPWRPDKAKGQSVEDCEDPDRQVLFDDIGQSLIRVNSPELKLRLMFHFLQFLGLPTGALDCSSAHTAPWWSSLLEDLSLLGEVPQAQPPLTAYHLPAPLVSPVGHMTTLQGARKWADLGKQGEEFLTNVFQMLLPLFPSKQRAVLYLCWLQYEKLKVLRCVRHGNKRRLRVQGKRSKRVAKCLLKEPENRGWLPLWREYAHLEWLLGNLADARKVFDSALVLGVAGGLADSSLCHLCLLYAQLEVEEAAGQSVAGGGQVGPATGSAAVYVLTKLAEGGSYAAFSGELAPVAVLKARRTYELALHTCLAGLEKQEDPGKELNAQGQKLGGLGQWNQPSLVSGLVGCYALFQYLTVGVEAAQAVYSLARERLGQLHSRPDANSDANLANANTDPSPASVASANRLASECEYLAVQQAALLHYHTSTSVYPLRPLRETLTSALQLHPTSAPLWRLYVQVENRYHSAGRARRFCHGIARGCASVVPRLFAISAEQHRKQLLDSAIRSCSQGEALPTLPENGLSNRIRSLFENALATEQGTHCPLLWRMNMHFLVSDGSVEKGRAVFYKALQDVPWAKGVYMDAVRLFPEHMQEYLDLLTEKELRLRLPMEEMDILLED"

     misc_feature    446..742
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(446..469,476..481,491..496,500..502,506..550,
                     557..565,569..577,602..610,629..634,638..643,650..670,
                     698..709,716..742)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    929..1927
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

taacatggcactgtttccagcgtttgcaggattagcgagtacaaaagttgacgaaccacataaagaactggaatggctgaccaaccaaagtttccgctccgacgaggctctttcccttcaccagcgtgcggtagaaaagtctatccagctcaagcagccagcagcagatacaagactgttgtcaagtgaggaggaggaggaagaccggaatgatgtttcgtccaagaagaggaagaagaaggagaagaagaagaagaagaagaagcacaggagaaagaggagcgggaggccttcagacagcagcgggtcggattcagacaccgtctatcccagcgaccttctgaaaaaggatgcagaggagcctagtcagcagccccaggtccagtgccagctggaggggaagtttgcgtggctggatgacctccagagtccccctgcccagctcttctgtctggaccgcaaagcagactctgctaactggcagtacaagtctctgtacaggggagacattgccaggtaccggaggaagggccagtcctgtctgggcctggacccacgcaggcaggccatcagctgggccgagtccgaatcctcaaacaggaagcgatctgacaagaacaggaagcagacagagcgctacttctgctcctctgcccgccctctgctgaaagcccctcccgttccctccctccccggggcgcctgcacccggccccaccctcgagtacatccccctgcccctctgccccaaggaggggggtgcaggggcgggatctggacccgtgagctgggtcaaccccctaggggtgtacgatgactccacctccctctggctacagggccgtggccacagtgagcaggggcagggccaggagccctccagggacaaggacagcagcgccgccctgctggctgggagggtggaggacttcaacaggaggctgagagagacgcccacagacactcagctctggctgcagttcttgcacttccaggatgaactgtgggatgcgggagggtttgggggggaggggggatcgagggaggcggagcgtggcggacggtcgttgcgagcgtctgtggagaagaagatgagcatcgcggagcgcgcgttggagagtaacccggggtgcgtggccctgcagctggagaggctgcgtctgagccgggagctgtgcgagcctgcagccctgcagaaagagtggaggaagctggtgttcctgcatcccaacagcgcccccatctggagggagtacctgctgttcacgcagagtcacttcagcaccttctccgtgtcaaaggtcaactccgcctacgggaagtgcctgagcacgctcgctgctgtgcaggatggaagtatgacgtcacacccagccctgcccggcacccaggaaagcatgctggacatctttgtgcagcagtgtcatttcctgcgtcaggcgggacactctgagaaggctgcgtgtctgttccaggctctgctagacttcaccttcttcaaaccagacagcgttaaagacctgcccaccagacagcaggtagagtttttcgagcccttctgggacagcggggaggccagggtgggagagaggggcgcccgaggctggaaggcctggatgcttcagcaggagagaggaggctggcttctacctaatacagatgatgatgatgatgatgatgaagatccagaagaggagctgaaggacaggacctggccaaaggggaggatctggttggacattgagacatcccgtgaggccaaccattggctgccctggaggccggacaaagctaagggccaatcggtggaagactgtgaggacccagacagacaggttctgtttgatgacatcggtcagtctctgattcgtgtgaatagtccagagctcaagctacgtctaatgtttcacttcctgcagttcctgggtttgcctacaggggcgctagactgctcctctgcccacaccgccccctggtggagctcactgcttgaggacctgtctctcctgggggaggtgccccaagctcagccgccactcacagcgtaccacctcccagccccattggtcagccccgtgggacacatgaccaccctgcagggtgccaggaagtgggcagatctgggcaagcagggggaggagtttctgaccaacgtgttccagatgcttctgcccctattcccttccaagcagagagcagttctgtatctctgctggctgcagtacgaaaaactcaaggtgctgcgctgcgtgcggcacggcaacaagcgtcgtcttcgcgtccaggggaagaggagcaagcgtgtggccaagtgtctcctcaaggagcctgagaaccgcggctggctgcctctctggcgcgaatacgcacacctggagtggcttctgggtaatctggcagacgcccgcaaggtgtttgactccgccctggtgctgggtgtagccggggggctggctgactcgtccctctgccacctctgtctgctgtacgcccagctagaagtagaggaggcagcaggacagagcgtggccgggggtggccaggttgggccagccacgggctcagctgctgtgtacgttctgaccaaactagctgagggggggagctacgcagctttttctggagagctggctcccgttgcggtgctgaaggctaggaggacctacgaactggccctgcacacctgcctggctggcctggagaagcaggaggaccccgggaaggaactgaatgctcaggggcagaagcttggaggcttggggcagtggaaccagcccagcctggtgtcgggcctggtgggctgctacgccctgttccagtacctgactgtgggggtggaggctgctcaggccgtgtacagcctggccagggaaaggctgggacagctccattccaggcctgacgctaacagcgacgctaacctggctaatgctaacacggatcctagcccagctagcgtagcgagtgctaaccggctagcctcggagtgcgagtacctggctgtccagcaggctgcgctgttgcactatcacaccagcaccagtgtgtacccgctgagacccctcagagagaccctcacctctgccctgcagctccaccccactagtgcccccctgtggaggctctatgtacaggtggaaaaccgttaccacagtgccggcagggcgcggaggttctgccacggcattgccaggggctgtgccagtgtggtgcctcggctctttgccatcagcgcggagcagcacaggaagcagcttctggattctgccatcaggtcttgttcccaaggcgaagcactccccaccctgccagagaacggacttagcaaccgtatccgctcgctgtttgagaacgccctagcgaccgagcaggggacccactgtcctctactgtggaggatgaacatgcacttcctggtgtctgatgggagtgtggagaagggcagggctgtcttctacaaggctttacaggatgtcccctgggccaagggagtgtacatggatgcggtgcgtctgttcccagagcacatgcaggagtatctggacctgctgacagagaaggagttgagactgaggctccccatggaggagatggacatcctgctggaggactgacgcttcccatgatgcactgctgctaccatgccaggagatggacatcctgctggaggactgatgcttcccatgatactgctgctaccatgccaggagaggctggttggatagacatcagatttcattggaaccgatgtgacactgtgaatttgggaatataaatattttgatgtatcccatttgaataatttacttgtttaataaatgttact

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