LOCUS       XM_066269665            6949 bp    mRNA    linear   MAM 05-JUL-2024
DEFINITION  PREDICTED: Saccopteryx bilineata argonaute RISC component 4 (AGO4),
            transcript variant X3, mRNA.
ACCESSION   XM_066269665
VERSION     XM_066269665.1
DBLINK      BioProject: PRJNA1130893
KEYWORDS    RefSeq.
SOURCE      Saccopteryx bilineata (greater sac-winged bat)
  ORGANISM  Saccopteryx bilineata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera;
            Emballonuridae; Emballonurinae; Saccopteryx.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_089492) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036850765.1-RS_2024_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/03/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6949
                     /organism="Saccopteryx bilineata"
                     /mol_type="mRNA"
                     /isolate="mSacBil1"
                     /db_xref="taxon:59482"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="liver"
                     /dev_stage="adult"
                     /geo_loc_name="Suriname: Sabajo"
                     /collection_date="2017-09-20"
                     /collected_by="Burton Lim"
     gene            1..6949
                     /gene="AGO4"
                     /note="argonaute RISC component 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 8
                     Proteins"
                     /db_xref="GeneID:136331348"
     CDS             420..2804
                     /gene="AGO4"
                     /codon_start=1
                     /product="protein argonaute-4 isoform X2"
                     /protein_id="XP_066125762.1"
                     /db_xref="GeneID:136331348"
                     /translation="

MVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKLTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA"

     misc_feature    429..683
                     /gene="AGO4"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    714..866
                     /gene="AGO4"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    867..1229
                     /gene="AGO4"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1023..1025,1068..1070,1110..1112,1122..1124,
                     1176..1178,1197..1199,1203..1205)
                     /gene="AGO4"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1368..2675
                     /gene="AGO4"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1779..1781,1791..1793,1827..1838,1845..1847,
                     1869..1871,1878..1880,1890..1892,1902..1904)
                     /gene="AGO4"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1983..1985,1989..1991,2229..2231,2643..2645)
                     /gene="AGO4"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      6949
                     /gene="AGO4"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

agggctccgtggacccggcccccggagccgtgcacgccccctccgcgagccaggaccccgggccgcgcgctccccgcgccccgtccccgcccgccgggcgcgcgcgctggctctcgctcccgctccagctggcagcggcggcggcagcggcggggattgtttttgttgtcgctgaggccggaagagccgtgggagccgggtccctgtccccgggccaggcgccgccgccgccgccgccccctgcccggcgcccgcatctccgcggcgcccctcctcagcgccaatattccggagatcaagcggtacgcggcggcggcggcggcggcggcggggcccggagcgggaagtgccggggaccggggcgaggcggcccccgccgccgccatggaggcgctgggaccagggaggtagtagatacaatggtgcggcacttcaagatgcagatatttggtgatcggcagcctgggtatgacggcaaaagaaacatgtacacagcacatccactaccaatcggacgggatagggttgatatggaagtgacccttccaggtgagggtaaagaccaaacctttaaagtgtctgttcagtgggtatcagttgtgagccttcagttgcttttagaagctttagccgggcacttgaatgaagtcccagatgactcagtacaagcacttgatgttatcacaagacaccttccctccatgaggtataccccagtgggtcgttcctttttctcacctccggaaggttactaccatcctctgggcggaggccgggaggtctggttcggctttcatcagtctgtgagaccagccatgtggaacatgatgctcaatattgatgtatctgcaactgctttctaccgggctcagcccatcattgagttcatgtgtgaggttttagatattcagaacatcaatgaacagaccaaacctcttacagactcccagcgtgtcaagtttaccaaagaaatcagaggtcttaaagtggaggtgactcactgtggacagatgaaacggaaatatcgagtttgtaatgtgactagacggcctgccagtcatcaaacttttcctttacagctagaaaatggtcaagctatggaatgcactgtagctcaatattttaagcaaaagtatagcctgcagctgaaataccctcatcttccctgtctccaagtgggacaagagcaaaagcatacatacttgccacttgaggtctgtaatattgtggcaggacaacgatgtataaagaaactcactgacaatcagacttccacaatgatcaaagccacggcaagatctgctcccgacagacaggaagaaatcagtagactggtgaagagtaacagcatggtgggtggacctgacccataccttaaagaatttggtattgttgtccacaatgaaatgacagagctcacaggcagggtacttccagcaccaatgctacaatatggaggccggaataaaacagtagccacacccaaccagggtgtctgggacatgcgaggaaagcagttttatgctggcattgaaattaaagtttgggcagttgcttgttttgcgcctcagaaacaatgtagggaagatttactaaagagtttcactgaccagctccgtaaaatctctaaggatgcagggatgcccatccagggtcagccatgtttctgcaagtacgcacagggtgcagacagcgtggagcccatgtttaaacatctgaaactgacatatgtgggcctacagctgatagtagtgatcttgcctgggaagacgccagtatatgcggaggtgaaacgtgttggagataccctcctgggtatggccacgcagtgtgtccaggtaaaaaatgtagtgaagacctcaccacagaccctttccaacctttgcctgaagataaatgcaaagcttggaggaattaacaacgtgcttgtacctcatcaaaggccatcagtgttccagcagcctgtcatcttcctgggagcagatgtcacacacccacctgcaggggacgggaaaaagccttccattgctgctgtcgttggcagtatggatggccacccaagccggtactgtgccaccgttcgggtgcagacctcccgccaggagatctcccaagagctcctctatagtcaggaggtaatccaggaccttactaacatggttcgagagctattgatccagttctacaaatccacacgcttcaaacccacacggatcatctattaccgtggaggggtatccgagggacaaatgaaacaggtagcttggccagaactaatagcaattcgaaaggcatgtattagcttggaagaagattaccggccaggaataacctatattgtggtacagaaaagacatcacacacgactcttctgtgcagataaaacagaaagggtgggtaaaagtggcaatgtaccagcgggcactaccgtggatagcaccatcacacatccatctgagtttgacttttacctctgtagtcatgcaggaattcagggaaccagccgtccttcacattaccaggtcttatgggatgacaactgtttcaccgcagatgagctccagctactgacgtaccagctatgtcacacatacgtgcggtgtacacgctcggtctctatcccagcccctgcatattatgcccggcttgtagcattcagagcaaggtatcatctggtggacaaagatcatgacagtgcagaaggcagtcatgtgtcaggacagagcaacggccgagatcctcaggccttggctaaagctgtgcagatccaccatgatacgcagcacacaatgtattttgcctgagagtctcagaagaactcaactaatttggcaccccatgcagcctcaaaatgtttccaatgcctaccgcttctagagagagccaagttgacttcagtttttcttctaccagcagctcggaatagttgcactgaataaatactttgcagcactgtctgatgtatcaacaaaattgagccattttttaaaagtaatagatactcatagattgtcttttctgatgcactggactaatttttacctcaacatgcaaaggctgatgataagcctgaactttctaaaggactttacaagaaaggtttctatggaatattttgctagctgcggtgttcaccgcatccctctagtcttatcagagaaggttattccttttttctgtattcatcgagtgggatgtctgcatcagtgggagagaaaaaccaaacaatctacttcagtttagtgtaactcttttaattgtatgggtccatagactttttaatggagatttctgacttcgccactgtaaatgcctttaatgagcattaattttttgaaagttttacagagttttattagttttactattttatcttattgatctgtacagacttgtactggtgcaagtacaggccgccaggcaattgcactatatttggctccagattcaaaagggcaattctcttatttgggtgactcttgtcaatgtgtaacacaaacagacataatgcctgtcatggtgacagataacactgccatgataaaaagtactcatgttttccccctctttgaaaaaaaattagttttagtatttttcaaagttttcaaaagtgcccattttatgctgctgtgtggtttgtcacatctacatggtttttaaacttttctcatagaaagttaactttggcaataaacattttttaaggtctctttactcccccctccccaacaatgagttttctagataaaattttggtatgattttattagctatttcttatagatcataatctgacaattcctaaaatcggtcagagaagacatatttccatgccttttttttttttttttttgtatttttctgaagctggaaatggggaggcaggcagtcaaacagactcctgcatgcgcccgaccgggatccacccggcacgcccaccagggggcgatgctctgcccatccggggccattgctctgttgcgaccagagccactccagcgcctggggcagaggccaaggagccgtccccagcgcccgggtcatcttttgctccaatggagcctcagctgcgggaggggaagagagagacagagaggaaggagagggggaagggtggagaagcagatgggcgcctcccctgtgtgccctgtccgggaatcgaacccggaacttccgcacgccaggccgacactctaccactgagccaaccggccagggcctttccatgccttttttaaagaattattttttatctgttttatagccacagttggtgtcctgtcactttgttttaaaataagctagagccaggatgcttccttactgggtcggctttgccaatccttaaggcacattgagtgatgctgcaacttgcaaaaacgtaccagcatttaaaactttttcctgggaatcaaggtttctatgtaattactcacagtgcaaattttgtgcttctctttcaacctgaaatgtacgtggtgaggtttccttgtttttagtaaagtaatactgaatagaaaggttgattattcttaatagacactggattccgttcacaggaagatgggattccttacgtgtccaagcaaagggagttgatctaaagcaaataccagttacaatgtaggggaaaatgtattttgtatttagtatagataatactttgtaaatggacaacagttacatagagtcttgatagttcagccagtattgcccagcccagatttcactggcttgtaactctctatcctgggacctcaggagtgagagctggaaaaggggataaaaggctcagagccacactccacatggatgaggaaggtgctgggggaagagatagacacaatgcagtaaaccgaatttgccccctctgtatggaaacactgaatatgatggtgaagggtgtttgcttgaacttattagccggtccaaatcttttaaactagccttctcaaaatcccagcaatataaagccctgtttttcttcagtcttttaaacaagcttgtaaatacatttgaagtttacatttctatgtgctgttgatcagcggcgccaccagtgtttgctgggactggtgtctggtgtctgagagttatataatgtatatagggtcctgtagctcattaagcggagtgcagacatccttatttctctgcatacagtgagatgaaagcaagctctgtaattgaggcacaatatagtgaagagatggcagatgttaatttcttaaggttttcctttcttgcaaatacctcacttggctactacaaatcaggagatgttggtgaggggctggctactgcttttattcacacttgttcagggagagcacagaaaatacccttcagcatggccaccctggacccaagaggaggaaaaacaagctttttttaggaggaggactcgccaaagtccaggatgtgaagaactcttggtggctggctggctggccagcgggcaccacacctgcacttgagtacctcaagcttgcttgttaacgcacagaagaagaaacttcacttctcaccatctcctggcacgaatagagcagggagcaaagcagggtgcctggaagccctgattcacttgcctgcagttgtgctacacgctcaaccttgaactctacagtttgtacaacctcagtcagtcctaacacactgggtcaaatgagtgtggtggtggaggaaaagccgggaggcctatttttataggaaaacagtacctttaagggtgcaacgctatcattttggacaaaaggaaagaaatatgaaagacctgagattattggaaaaaacttgctgagggttaaatcttgaagaaataatcactggaaaaaaatgaagagaagaaataactgctgcagaatcagagttgcagcaatactattgcaagcaagtctgaatgcatagttttaattgggcttgaccatttgaatttgtaaccctctggactgactgaatcgttatgcatgtgtcaatcaatgggaggtgtgcattctctaaaagtaggtttaggatgcttggggttttttttttacaatgcagcctgtttaggcactgtcatgtagtgtgaaagatttaaatgtagcaatgctaaagagtaacaatttggggacaagttgcggggacattaagagagtggtgaagatccaaatgttgaaccaattatattttgttgttagctgttgaaccctgggaaatttataaagagaactagctggcttaacgcagctagttctaggcaggcagaacacattcattcttactgtaaattctatttgctgcttccaaaggtgatgatttacgagcagacatactctatatggtctgtattttaggaactggtgtccagcctatatcagagcttagctacatgctcagctaacctacccttcctgtgggaaatggtaatccactttttaacaaggctcaccctctctaccctgccctagcaaccctttgtggatatgctgtaaggttttcttgctcaatagcaaggtggtaactctgctttcattttaagaaagtggaggctgagggcattgtatcaatacagcatcaactccaaggatttttccttgtagaattaaagggaagatccttgctattgattaaccattttcttatcccttgctattgacatagtcatgctctttctgtgtctagtggctgaaaatgtttgcatttgttcatttgactaatggtgtaatttttgtttctatattgtttaacatgtaatgttttaaaatgtattttattaaagttggactggatgtatgtctctagcaatacgaggtactttctaaactattaagggagaggtggtatacccatgttgagataagatgatgattgtttaaattttacaatttttttttggcctgcagggatattttgtgtttttgtgtccaaaaaagaataaattggcattcttgtgccaaaagttgtt

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