LOCUS       XM_059890179            4697 bp    mRNA    linear   MAM 26-DEC-2024
DEFINITION  PREDICTED: Bos taurus NRDE-2, necessary for RNA interference,
            domain containing (NRDE2), transcript variant X1, mRNA.
ACCESSION   XM_059890179
VERSION     XM_059890179.1
DBLINK      BioProject: PRJNA450837
KEYWORDS    RefSeq.
SOURCE      Bos taurus (domestic cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_037337.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_002263795.3-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/22/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4697
                     /organism="Bos taurus"
                     /mol_type="mRNA"
                     /isolate="L1 Dominette 01449 registration number 42190680"
                     /db_xref="taxon:9913"
                     /chromosome="10"
                     /sex="female"
                     /tissue_type="left lung"
                     /breed="Hereford"
     gene            1..4697
                     /gene="NRDE2"
                     /gene_synonym="C10H14orf102; C14orf102"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 9 ESTs, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="BGD:BT21207"
                     /db_xref="GeneID:100138828"
                     /db_xref="VGNC:VGNC:32259"
     CDS             1077..3854
                     /gene="NRDE2"
                     /gene_synonym="C10H14orf102; C14orf102"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X1"
                     /protein_id="XP_059746162.1"
                     /db_xref="GeneID:100138828"
                     /db_xref="BGD:BT21207"
                     /db_xref="VGNC:VGNC:32259"
                     /translation="

MNVDGLAVSSQPEALALEPLSFIPVKGVDDAAPPATSWLNPLGIYDQATTQWLQGQGPSEQESRPPDSQPDRESALLKARVEEFNRKVRESPRDTELWMAFVAFQDELMRSPGLYAVEEGEPETRKRSLRLVLEKKLAILERAIESNPSSVDLKLAKLKLCAEFWEPATLLKEWQKLIFLHPNNTALWQKYLLFCQSQFSTFSVSKIQSLYGKCLSTLSAVRDGSIVSHPELPGTEEAMFALFLQQCHFLRQAGHSEKAVSLFQAMVDFTFFKPDSVKGLPTKGQVEFFEPFWDSGEPRAGEKGARGWRAWMHQQEWGGWVAVGADDDDEEPEEEDQEIRDKALPRWQIWLAAERSRDHRHWRPWRPDKARKQTEEDCEDPERQVLFDDLGQSLIRLSSPDLQFQMMAAFLQFLGVPSGFSPPTPCLYLAMDENSIFDSELYDEKPLTFLDLSCSGVSCVGRMEPLGGRRWPRGPSREGEEFIRNVFHLALPLFAGRERSQLCVSWLRYEITKVVWCLHTKNKKRLKSQGKNCKKLAKNLLKEPDNRNSFCLWQQYAHLEWLLGNTEDARKVFDAALGTAGSRGLEDPELCELGLLYAALETELSPPVGGAAPARAVHVLSGLAERRPYGPCTGQVSAVHVLKARRAYEHALQDWLGERRGPDPGPPDRFSRLVSLAKCFMLFQYLTVGVDAAGRVYEQVFAGLRGSVSSEAAGLEGALEAVTLMHTSLLRFHGRVAAHPLAPLREALSEALRLYPGNQLLWRAYVQIQSKSHSASRTRRFFHAITRSTKLLEPWLFAIEAERMRKRLVDAVQRVDGREVHATLPETGLTHRIRALFESAVRSDHGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKALYMDAVEYFPDEMQEVVDLMTEKELRVRLPLEELELLLED"

     misc_feature    1323..2321
                     /gene="NRDE2"
                     /gene_synonym="C10H14orf102; C14orf102"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
     polyA_site      4697
                     /gene="NRDE2"
                     /gene_synonym="C10H14orf102; C14orf102"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

ctggcccttgtccagcgttggctgtttcgagtacgcttgtaacaagcttgcgagaacgcttgtgcacagccctttgtgtagggttgcggtttcccttttcttgggtaaatccctgggaatagaattgctgggccacggggcgaggtctgcgtttgggtttcgtttgttttttactgccaggcccgttccccccggcggcccgtgagccccggctcccctccaggtggctggccgcggctcggtgtcgccgccctttccctcatcctggctgtcctggtgggtctgcgctcggggcaccgtggttctcgcgggcctttcgttggtgactcacgacgctgaccacttcttcatgtgtttacggccgcgcgtgtcttttgtgccgtttctgctcacatcttttgctgatgtttgaattgggttgtttgtgtagcacacacacggaaagggcacagttttcctcagctttcctacagatactcagcagtcatgtgtttgtagctccggggacgcctacacgacccataaaagcattttagagcccagcctcttttcctgtagggtagaaaatagccaaatgtaattttatttgacacactttgtctcgggattaaaaaaagaaccttagacctctctattatcttctgaagtagacagcacggaggaaaagggactggtgtaggagtcggagggcctggcgtcacctgaggcctcagcgtccttattgaagaacaccgtcgagggcaggcgatggtttcccctcgcctggcacccgcggtgcggccctaggtggcgtgatgacggtgctgtgcagggcttaggggcgggtgggtactgaggtctggaagacaggcgtgatctgaaattcgtgagacgcagacgaaacagcagggtagaggaaaagtcctcgtacttctctgagtagaaacagtttggagggaagatacaagaggaaaggagactcctgcctcggcctcaacccgaagaagcaatgtatatcttgggaggggaattccacagaaaagaagcgttcccacaagcacatcgagcgctactttacgaagaagagcgtggggttgatgaacgtggacggcctcgccgtcagcagtcagcccgaagctctggcgttggagccgctctcctttatcccggtgaagggcgtggatgacgcggctccccctgctaccagctggctgaaccctctggggatttacgaccaagccactacgcagtggttacagggacagggtccttcagagcaggagtccaggccaccagactcacagcccgacagagagagcgcgctcctcaaggccagggtggaggagtttaacaggaaggtccgcgagagccctcgggacacggagctgtggatggccttcgttgctttccaggacgagctcatgagaagtccgggcctctatgccgtggaggaaggagagccggagacgcggaagcggtccctccggctggtcctggagaagaagctggccatcctggagcgggccatcgagagcaacccgagcagtgtggacctgaagctcgccaagctgaagctctgcgccgagttctgggagcccgccactctgctcaaagagtggcagaaactgatcttcttacatcccaacaacacagccctctggcagaaatacctgttgttctgccagagccagttcagcaccttctccgtatcaaaaattcagagtctgtacgggaagtgcttgagcaccctgtccgccgtgagggacggcagcatcgtctcccaccccgagctgcccggcaccgaggaggccatgtttgccctcttcctccagcagtgccacttccttcggcaggctggccactccgagaaggccgtgtctctgttccaggccatggtcgacttcacgttcttcaagccggacagcgtgaagggcctgcccaccaaaggccaggtggagttctttgagcccttctgggacagcggcgagccccgggccggggagaagggcgcccgaggctggcgagcctggatgcaccagcaggagtggggcggctgggtggccgtcggcgcagatgacgacgacgaggagccggaggaggaagaccaggagattagagacaaggctctgccccggtggcagatctggctggccgccgagcggtcccgagaccacaggcactggaggccgtggcgcccggacaaggccaggaagcagacggaggaagactgcgaggaccccgagagacaggtgttgtttgacgatcttgggcagtctctgatccgactgtccagcccggatctccagtttcagatgatggcggccttcctgcagttcctgggggtgccttccggcttcagcccccccaccccctgcctctatctggccatggatgagaacagcatcttcgacagcgaactttatgatgaaaagcctttgactttcctcgacctctcctgctccggcgtcagctgtgtaggccgcatggagcccctgggtggccggcgctggccccggggtcccagtcgagagggcgaggagtttatccgcaatgtcttccacctggcactgcctctgtttgcaggcagggagcggtctcagctctgcgtctcctggctacggtacgagatcaccaaggtcgtttggtgtctgcacactaaaaacaagaagagattaaagtcacaaggaaagaactgcaaaaaactagccaagaatctcctcaaggagccggacaaccgcaacagcttttgcctctggcagcagtatgcgcatctggagtggttgctgggcaacacagaggatgcccggaaggtcttcgacgcggccctgggcactgccgggagccggggcctggaggacccggagctctgtgagctcggcctgctctacgccgcgctggagacggagctgtcgccgcccgtgggcggggccgccccggcccgcgccgtgcacgtgctgagcgggctggcggagcgccgcccctacgggccgtgcacgggacaggtgtcggctgtgcacgttttgaaggctcggagggcatacgaacacgcgctgcaggactggctgggggagcgccgcggccccgacccaggcccccccgaccgcttcagccgcctggtcagcctggcgaagtgcttcatgctcttccagtacctgaccgtgggggtcgacgccgctgggcgcgtctacgagcaggtgtttgcggggctcaggggctctgtctcctcggaggctgccggcctggagggcgccctggaggccgtcaccctgatgcacaccagcctgctcaggttccacggcagggttgccgcccacccgctggctcccctgcgagaggcgctctcagaggctttacggttgtacccgggcaaccagcttctctggagggcgtacgtgcagattcagagcaagtcgcacagcgccagcaggaccagaagattcttccacgccatcaccaggtccaccaaactcctggagccctggctgtttgcgatcgaagcggagaggatgcggaagaggctggtggacgccgtgcagagggtggacggtagagaggtccatgccacccttcccgagaccggcctgacgcaccggatcagagccctgtttgagagcgccgtgcggagcgaccacggcagccagtgccccctgctgtggaggatgtacctgaacttcctggtttccttaggaaataaagaaagaagcaaaggtgtgttctacaaagcactgcagaattgtccttgggcaaaggcgctgtacatggatgccgtcgagtacttccccgacgagatgcaggaggtcgtggacctgatgacggagaaggagctgcgggtgcgcctgccgctcgaggagctggagctgctgctggaggactagacgctgggggccgggcccagccccggaacacgggcacgcgcatgcccagacctgtgccctgaagggtcctccctgacgcgcgtctaggctgtcagtctcaccttctgcagtttctgcacatgcgaatgacacaaagctgacattctgcacacgatacatgtgaatgtgtggaatgtgaatgtggccggttggcgtgcacagacaaggatcacgccaaagctgtcacggctcgtgtgggtccttctggtccactctcccctgcccagcccgggtgaaggttcttctgtgggcatccttggggatcctgccaagtctcctggctcttgcagtccaaagaaaggtctggttactcaccaggccctccgccctgcggctggtgagcccattctgcccatttttcagaccagagcagctgggagtcgtgtaaagcttggagttctcagctgcatcacacgtgtccttcctgttcccggagctccactcgtggacatctcgcctgcagacccggcagccagcgtcgccggaagctcatgcgcctggagaccctgggcccacccggccctgctgagtcagatggggctctaggaggactgagtcgggactgaacaaacaaggaccccgctgcaggggagcgcggcctgctcctccccagcaaacccatctctgcctcagagacgccgaacgttcgcttccagctgcgtcagctgcgctctcatccgattttcaagagcggtgatcaacacccgacagagcggaaatgctttttgttctccgaggtcctgcttttttaaacacagtggacttctctgcattgcgtttcttattaaatcatgctctctagaa

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