LOCUS       XM_055254951            9521 bp    mRNA    linear   PRI 17-JUL-2024
DEFINITION  PREDICTED: Symphalangus syndactylus protein argonaute-3
            (LOC129468935), transcript variant X5, mRNA.
ACCESSION   XM_055254951
VERSION     XM_055254951.2
DBLINK      BioProject: PRJNA946760
KEYWORDS    RefSeq.
SOURCE      Symphalangus syndactylus (siamang)
  ORGANISM  Symphalangus syndactylus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hylobatidae; Symphalangus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_072441) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Mar 6, 2024 this sequence version replaced XM_055254951.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_028878055.3-RS_2024_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/16/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9521
                     /organism="Symphalangus syndactylus"
                     /mol_type="mRNA"
                     /isolate="Jambi"
                     /db_xref="taxon:9590"
                     /chromosome="12"
                     /sex="male"
                     /cell_line="Jambi"
                     /cell_type="lymphoblastoid"
                     /tissue_type="blood"
     gene            1..9521
                     /gene="LOC129468935"
                     /note="protein argonaute-3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 41
                     long SRA reads, 11 Proteins"
                     /db_xref="GeneID:129468935"
     CDS             188..2068
                     /gene="LOC129468935"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X4"
                     /protein_id="XP_055110926.1"
                     /db_xref="GeneID:129468935"
                     /translation="

MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    188..529
                     /gene="LOC129468935"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(323..325,368..370,410..412,422..424,476..478,
                     497..499,503..505)
                     /gene="LOC129468935"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    662..1939
                     /gene="LOC129468935"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1073..1075,1085..1087,1121..1132,1139..1141,
                     1163..1165,1172..1174,1184..1186,1196..1198)
                     /gene="LOC129468935"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1277..1279,1283..1285,1493..1495,1907..1909)
                     /gene="LOC129468935"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      9521
                     /gene="LOC129468935"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

atatgaccaccctctgggagggggcagggaagtgtggtttggattccatcagtctgttcggcctgccatgtggaaaatgatgcttaatatcgatgttagaaactggaaatgtttctaaagtttatttggatggaagtttagcatttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgatattcataatattgatgaacaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaaaggtttgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacaaggaggcctgccagtcatcaaacctttcctttacagttagaaaatggccaaactgtggagagaacggtagcgcagtatttcagagaaaagtatactcttcagctgaagtacccgcaccttccctgtctgcaagtcgggcaggagcagaaacacacctacctgccgctagaagtctgtaatattgtggcaggacaacgatgtatcaagaagctaacagacaatcagacttccactatgatcaaggcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaagttcgggatgaaatggctcatgtaactggacgtgtacttccagcacctatgctccagtatggaggacggaatcggacagtagcaacaccgagccacggagtatgggacatgcgagggaaacaattccacacaggagttgaaatcaaaatgtgggctatcgcttgttttgccacccagaggcagtgcagagaagaaatactgaagggtttcacagaccagctgcgtaagatttctaaggatgcagggatgcccatccagggccagccatgcttctgcaaatatgcacagggggcagacagcgtagagcccatgttccggcatctcaagaacacatattctggcctacagcttattatcgtcatcctgccagggaagacaccagtgtatgcggaagtgaaacgtgtaggagacacacttttgggtatggctacacaatgtgttcaagtcaagaatgtaataaaaacatctcctcaaactctctcaaacttgtgcctaaagataaatgttaaactcggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagccgatgtcactcatccacctgctggtgatggaaagaagccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgccacagtaagagttcagagaccccggcaggagatcatccaggacttggcctccatggtccgggaacttcttattcaattttataagtcaactcggttcaagcctactcgtatcatcttttatcgggatggtgtttcagaggggcagtttaggcaggtattatattatgaactactagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtagttcagaagagacatcacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagacattacacacccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagtcgtccttcacactatcatgttttgtgggatgataactgctttactgcagatgaacttcagctgctaacttaccagctctgccacacttacgtacgctgtacacgatctgtttctatacctgcaccagcgtattatgctcacctggtagcatttagagccagatatcatctcgtggacaaagaacatgacagtgctgaaggaagtcacgtttcaggacaaagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtacttcgcttaaatagtccaagtatattctctgagaggaagtactgaaagatgaattgacatacaacgtatgtttccagtggagtcaattgagtaaggacacctccagccatacagaaaccaacactgtgtgggggccaaggtctgatccttatgttaatacaaggaagattgtttacttcatcaaggaacacagcatcattatgcaatatgaaaccagccaactgctttttgtgcggtctcctataggaagtatcgcaattgttttgttttcatttcttgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaagtaaagaaaaagtaaatgatggtttaaaaaatacacaccttcatgaataatcaaagtgatttttcaaaattatatgtgcaaaaaatgtgcattcatctattcttgtaaaaggtgtctgtgtatttttaaaatatatacatccatacttcatatgcatatatatctagatctggattgataatagatatatatgtgtctgttatatattttagagttcattccactggggaactttctttcccttttattctacccccactaccgcctttatttctctatttcccttgccttcatcacctacatttttttcctaatcctaccagtgacattcaaatgttgacgtatctggttcgtttgaatataaaatatggcaaactagatttctacttttattttgcataccctactcctgactcctatctcatacacaattctgagttctcaactcttgatattactgtcttaagaaacaaaattttatatatatatatatgtatgcatacatacacagacacatacacacacatatatatacataaaataactttctgtgagagtgtgtctctcccctcccgctcagaacatacatttaccatttgggcaatttgtatataagcagtagcaacctgcactattccttctcttttttctttttcttttttttttgttttttatttttttatgagacagagtctcgctctgtcactaggctggagtgcagtggcgagatctcggctcactgcaacttccgcctctcgggttcaagcaattctcctgcctcagcctcccgagtagctggtactacaggcatgtgccaccacacccaactaatttttgtatttttagtagagacggggtttcaccgtgttggccaggatggtctcgatctcttgaccttgtgatccacccgcctcgacctcccaaagtgctgggattacaggcgtgagccaccacacccggcctactattctttttctttagtgagtttgttaaagctgctataaatataaaacctgtcagaagttgtaactctttctctctgataagtgatgtgttttctgaagccttctgtttctatgggttatacatggaaattctttaaagattttataaagggtaaatattttaaaagattagaactctgtagggttgagacctctgaaattgagtagagagagagaagggtttgttgagggatttttttgttttgttttttgatagtttacttgctgcctctcataccttaatgtgattttcatatattttttatatatacatgtatgtgtgtgtatataaacacatatgtatgtgtttggaagtgtagcttccttttcttttatatttattagaatagtgctttaataattatagaattgtattggcagcatcttttatagacatataatcatgtttattttaagaactgacaacttgtttttgctatcctttagtgcaataagcagttttaaaggaaagttgtgtctgtttgcatctttaccatggatagtaggaggaacaggcacctccataatttaaaagggcaaataatacagccttaatttcagaaggaaagttttgtaattttcggttttaaagcatatcttttaaaattcatcatgataaaaggctggatgcggtggctcatgcctataatcctagcgctttgggaggccgagacaggtgtattacctgagctcaggagtttgagaccagcctggccaacgtggtgaaaccccatctctactaaaaatacaaaaattagctgggcgtggtagcaggcacctctaatcccagctactcgggaggctgaggcaggattgcttgaacccaggaggtggaagttgcagtgagccaagattgcaccattgcactccagcctgggcaacaaatgcaaaactccatctcaaaagaaaaaaaaatcataatgaaaatgaagtgaaattgcctaaatgagtccaacttgaatattagaaataaagttgaacttttatataagaaataatcgtgaatagcttaacatatttaaattatttgcaaatagatgtgtttattgaagaatcatattggctagatgctcattttcatttactaaaatgaatcaggaaaatgcaagataatattttaaaacttgtgctaatgtatcaccagtggaactttccttttaaaattaaggtgatagtaacaaaggaagttaggactttgatcattttaaatcagttaaatcactgaaatgtgggaaattgttttacaaaacttttattgattacactttaaggtgttaaaaagtactataaagctatcaaaaccgagtttatcagtaacattggattcaggggagctttgcactttgtaactcatgaaaattgcattttgattttttttttttgcactggttcagagtatagatactacagattgtttccagtgggcattgttgttagcctttcagaattccatctgcacatgaaacctaatggatttaagatctttagtttctctcttacctgtaatccactattattgccaattcactgtattttgagcctaaaatctgagcccatgtcctccgacaggcatgaaatcttttgtccctctgccagaaaactacgaaagtactgtattttgtgtgtttattattttgaagtgtctgaaatgcaatttacaacactgttgcaaagaactttacaaaaggtaatatttgtatcgtatatacattttttctcccagccttctcccatctcctccagaaaaatttcctataaagatggatttttttacactgaaattttactgaatatagtcaggatcatgggcaagagaagaaaatagtatacccaagatgataaaaagttaattcatctatgcttggtcaatgtgagtaaaacatcttcctttatcatgggagctgcacagattcatgtgggaaactttagggagtgactatagataccctttctctatggactctgtcacctaattttcagtcactcatatatgctagagtggagcccttaatttaaatctatttggaagaacttttttaagatgaaaaatattttttctaaattataaagctttaccttttgagtgatttctttttaagagtgctcttacactagtcagctagtgtaagagctagtttaaagttgattaacttgaaagaatatgtatactatatttctattttgctaacaaatggtatattaattaccactggttcttaattacaagaaaacttgtgcttagaattttaagataaaaggctaagtgaccaatgcttcttgaaatttgtcctatttattgttgcacttctggtgtagaatttctaatcttttttattttaaaaaagttttgcttttttttaagttaaacatgaaattcacagtggcccttctgctcctgcccttgctcactaactatatcatgaatgctaaattttggtcttcttttttctatgatgtgtcttacaagactgactgtaaaatatcagtctggcaactagataattgattttcatatgaagaagagttgggagtttaatgtatattcttgatggttaatctgtctacataaagtgctgatacatgtattatattacagtatcacgttactggcatggaggaccatacacttccaatactgtagctgctatatttatttaagtagagtctgacagttactgcactaaacaataaggagataagcaggattcaaggctagtgttagacccttttttttcctaagagtaaggacacggaatatcaaagtaacaaagggtgctgccattttagtttcaatttaatatcaggatattctttgttttagaaatgtagattttgacttttacagtttgaaaaagggtacctcagcctcctcagtactggttttttggcacatttcaacagaaatattagattccctttctttttcttaatagtgatcttctaacaagtttcttggagaaactattgttctaagggaaatccctgtttataacctattaatatatttctattcctagaagagagtctggcaggggttctagtaggaattactgagtgtttcagaaggcacttgatagcggcatctctgctttccagcacagggattctcagccttctaaagatctagaccagtttccaagctagcttctccacagcccaccactgcctagtgtttacttgtgtattctctaatggattttaggaggataggccttctgacagacagaatcacgaaagacttaaggcatgtctagggaaataaaagctgacttgcccttcagcaggaatgactggcagcggatctctgtgttcaaggaaagggtgagcgctaagcatgccagtgatggatccaaagtatttagatggattgcacaccaggaattagagaccatttgtgactcaaggaacttgatggatctgtttagagacctacatgaatttgccaagggcagtgatttttatgaaattcaagaagcaaacgacttggatacagctagaatatgttgcagtcttcctatttcaaacttgattttaatatttttaccaagaagtttaactgacaactctgcaaaattttcattcagtatcattaaacctgagttaaatgtttgcttagcttatcctcttagatgttcttctgttgaacaggcaggttgcccttaacagtaacttgctacttaaattaccttttattagttagtcaagctgcaaaaatatcattagtctggcatctttattttggctttatccatatgaagtattcattattttcattctttctgagaattcataaatgtcttaaagcttcagtaagaattgttgggaggtttgacatcaagtaacgccttcctgtgtagcagtataaccctaatttagaacccttgttttcctatttcagtcctcatatttgatcatagaaaagcacttttgtgattctataggggtcaaaaaataagccaagaataggtaagtcagtacagaaatcagaaagtgagaattttctccaaaaaagcttttaaaaaagtcctgtttatactaagaacattctcgatcagttgcaatgttagaaatgatactgtgattagtgaatgccaagctgagtcccaggaagcagggagggggagtgtgtgtgtgtgtgtgtgtgtgtatgagtgtgtatatatataatctcacacacacacacacacacaaagggaaaaattattttgacttttttcctacttttaaaatggcacatttaagtttgtaattttccatgtcagtcaacataatttttcaaactaagatataatggtcaaggcttgtgctaatattacctactactcattgacatttatattactttacccatcaaaactagtactccagatgtttacatcattgattaaatctcaagaatcttttgttcttaaaatatggaagttaaagattttaatttgaattaaagacagaaggatgataaattcaatatagagggttgagatttaccagtgagaaaccctgttgaagtatcaggtaaatggtgtgataaaattagaatcctatcaaatcacctatccagccattggggtcccttccttttttagactaatttctaaggtaaccaaaatctgatgtatctatgttagggtctcagtaaagcaaagatgtttgtcagggcatagactcttgagttaaattttttaatcattttttaaagcaaggcggttcttagaaagtgccttttcagaagatggtgctgtagatttttatttttcaaatagcacgaagctaagaattttaaagataaattattttagaactccaagagtgtgacagtttcataaaaataatgttagttgttgtcctgaatctcgtccaagggaaccaagaaaagcttttatgcagtaaagtatctaggtaaatgctcaccaaatttattttgtaaatttgaaaacaaaatatttagtagaattacctcttttaattcccaactgtgttggaggaaatccataatgcacataaaacagcaaacctacttaactttttaacaagattatgggtatagtaccagtgtccaaagggaaatgtaacttgcctggaatcataggcaacattttctaattaatcttttttttttttttttttttgagacaaagtctcactctgtcacctaggctggagtgcagtggtgcgatctcagcttactgcaaactccgcctcccgggttcaagtgattctcgtgcctcagcctcccaagtagctgggattacaggcatgcaccaccacacccggcctaattagtcattattaagaaggactgctcataaaggcagtaccaaatcatcattcagatcagcttaagtgagaaagcaaaatgatgatctctattgttagagaaattttcttttctagacaccaaggaatattttaaatgattttttgttttttctaggatgcaggaactatgaaaaatgatgacaaggcatttaaaagggtatgatcagttaaatagaagtaggatgtacaaaattgtgcttaaggggaaataagcaaaagaaaggaaaatagcaggacctttcatactaattagaaatgtagttacctaccagagggcaactttgctccataccaggaagcagtaaatagcagtaaatgatcatctaggcacttgtttcctgtgaatttggtgagcattcttccagaaaataagactaaaagcaaacaacaacaaaaaaaataccacacctcagtaaccttgtatgctgcattatataataatgatagtaaaattatattgtttggagtgtactgtgtctgtttgcaaatatacatgcacattaaacttttttgtttttataatgtcttaatagcaattatgagtttatttttgttaagattaatttttctattgtgatgtttatatttattggcaatttgtgtgcaacttttatattttgcttgttggttttaaggtattttatttttatagatatttctagctttcctcattctttgtaatagcagcaaagattaagatggagtgttaatataccaaccaaactacgaattccataaactctagagtttggatttttaccaataaaccattaacactattttgtaacttagaa

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