LOCUS       XM_019726515            5581 bp    mRNA    linear   MAM 22-DEC-2016
DEFINITION  PREDICTED: Rhinolophus sinicus argonaute 3, RISC catalytic
            component (AGO3), transcript variant X6, mRNA.
ACCESSION   XM_019726515
VERSION     XM_019726515.1
DBLINK      BioProject: PRJNA358073
KEYWORDS    RefSeq.
SOURCE      Rhinolophus sinicus (Chinese rufous horseshoe bat)
  ORGANISM  Rhinolophus sinicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera;
            Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_017738966.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Rhinolophus sinicus Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5581
                     /organism="Rhinolophus sinicus"
                     /mol_type="mRNA"
                     /isolate="Zhonghua_01"
                     /db_xref="taxon:89399"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="muscle"
     gene            1..5581
                     /gene="AGO3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:109444829"
     CDS             197..2077
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X5"
                     /protein_id="XP_019582074.1"
                     /db_xref="GeneID:109444829"
                     /translation="

MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFNADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    197..538
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(332..334,377..379,419..421,431..433,485..487,
                     506..508,512..514)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    671..1948
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1082..1084,1094..1096,1130..1141,1148..1150,
                     1172..1174,1181..1183,1193..1195,1205..1207)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1286..1288,1292..1294,1502..1504,1916..1918)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gaatagatagaggagaaaaaactaatctgagaagccagttaggaggctttttcaatcactagttcaggtttcagtctacatgttacttccttgagaagcagtatttgacacccttcacccccccatccagccatcccccaagtctgagttagtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgagcaaccaagacctctgactgattcgcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacgagaaggcctgccagtcatcaaacctttcctttgcagttagaaaatggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaaacatacatacctgccactagaagtctgtaatattgtggcagggcaacgatgtatcaagaagctaacggacaatcagacttccactatgatcaaagcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaagttcgggatgaaatggcccatgtaaccggacgcgtacttccagcacctatgctccagtatggaggacggaatcgtacagtagcaacaccaagccatggagtgtgggacatgcgagggaaacaattccacacgggagtggaaatcaaaatgtgggccatagcttgttttgccacacagaggcagtgcagagaagaaatactgaagggtttcacggaccagctgcgtaagatttctaaagatgcggggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactctgggctgcagctcattatcgtcattctgccagggaagacgccagtgtatgcggaagtgaaacgtgtaggagatacacttttgggtatggctacacagtgtgttcaagtcaagaacgtaataaaaacatcccctcaaactctctcaaacttgtgcctaaagataaatgttaaactcggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcactcacccaccagctggtgatgggaagaagccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgccacagtaagagttcagagaccccgacaggagatcatccaggacttggcctccatggtccgagaacttctcattcaattttataagtcaactcgattcaaacctactcgtatcatcttttatcgggatggtgtttcagagggacagtttaggcaggtattatattatgaactactagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtggttcagaagagacatcacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagacattacacacccctatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgataactgctttaatgcagatgaacttcagctgctaacttaccagctctgccacacttatgtgcgctgtacacgatctgtttctatacctgcaccagcgtattatgctcacctggtggcattcagagccagatatcatctcgtagacaaagaacatgacagtgctgaaggaagtcacgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaaatgtccaaggatgttctcggagaggaagaactgaaagatgaatcgacatacaacctatgtttccagtggagtcagttaggtggtgatgcctgcagccatacagaaaccaacactgtggggaccagggtctgatttttatgttgatactaggaagattgtttacttcatgaagaaacacagcaccattatgcaatatgaaaccagccaactgcttttttgtgcaatctcctgtaggaagtgtcgccattgttttgttttcactttctcgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaaaaaaaaaaaggaaaggaaaggtaaatgatggtttttaaaaaaacatgcctacatgaataatcagagattgttcacaattacgtgtgcaaaaaaattaatgtgcattcgtgtattcttgtaaaaggtatctgtgtatattttaaatatatacatgtatacttcatatgcatatatatctggatctacactgataatagatatatatgttctttgtgtatgttttatagttcattccattggggaacttcctttcccttttattatcctcccaccaccacttttatttctctctctacctcccttgcctttatctcctatatttttttccctaatcctacaagtgacattcaaatgctcatgtatctggttcatttgaatatgaagcatgacaaactagactttcattttgcacacccactcctgtctcttttctcatacaccattctgagtcctcaattcttgatattgcttacttaagaaacaaagttactttatatatgtgtgtgtgtgtatacatacacacacacacatatgtgtgtatgtgtttttgtgagagtttgtgtttgccccctccagctctgaacttacatttgccatttgtgcaatgtgtacataagcagtagcaacctaaactattctttttctttagtgagtatgttaaagctgctataaatataaaacctgtcagaagtttaactttttctgtctataagtgatatgtattcaaaagacttctgtttctatggctctataagtgatatgtattcaaaagacttctgtttctatgggttatacatggagatcccttaaagcttttataaagggtaaatattttaaatgattggaactctgtagggttgaggcctctgaaattgggtagagagagagaaggggttattgaggtttttataattttttttttttttttgctaggttacttgctgcctctcataccttaatgtgattttcatatatatatatttttatatatatgtatgtgtgtatatataaacatatatgtatgtgttttgaagtatagcttccttttctatttattaggatagtgctttaataattatagaactgtattggcaacatcattgatggaaatataatcatgtttatttgaagaactgacaactggtttttgctgtcttttagtgcaataagcagttttaaaggaaagctgtgtctgtttgacgtctttaccacagatagtgggagaaacaggcacctccataattttaaaagagcaaagtaacaccgccttaatttcaaaaggaaagttttgtaattttcaaatctaaagcatgtctttaaaaatcataatgaaaatgaaggaagttaatatcctaaatgagactgaccataaatattaaaaataaagttgaactgtgatttaagaaatcaccatgaatagattaaaatttagaagatattaaaattcttcgaaaataaatcatgtttattgaaaaatcatactggttaggtacccattttcattaactaaaatgaattaggaaaatgtgatatattttttttaatttttgctaatttatcaccagtgactttccttttaaaattagggttatggtgacaaaggcagttaggactttgaacgttttaaatgagttaaatcactgaaatgtgggaaaaacttttggaaaacttttttttattattgacttcactttacggtattaaaaagtactatgaagctgtcaaaaccaagttcaccagtaacattggattcaggggagctttgcactttttaactcatgaaaattgcatttaaaatttttttttgcactggttcatagtataaatattacagattgtttccagtgggcattgttattagcctttcagaattccatctgctcatgaaaatgaatggattagctctatagttcctcttacctgtaatccagtcttattgccaatttactgtattttgagcctaaaacctgagcccatgtcctccaacaggtatgaaatcttttgtccctctgccagaaaactaagaaagtactgtattttgtatgtttattatattgaagtgtctgaaatgcaatttacaacactgtctcaaagttctttacatgagataatatttatatagtatgtacattttttctcccaactctccctcctcctccaaaaaatttctgttatatatatatgattttgtttttttacgttgaaacttcactgaatacagtagtcaggaacatggacaagagaagaaaatggtgtgtcctagatggtaaaaacttgattgctgtgtgcttgttcagtgtgagtaaaacatcttcctttatctgtgggagttgcagtttcatgtgggaaactttaggacccagggaagagctgtagatacactttccctatttactgctttacctaattttcagttacttattttcacctgcgctagactgaagcccgtaatttaaatctatttggaaggacttttacagaggaaaaagaaaaaaattttaatataaagctttacctttgaagtgagttctttttttagggtttctttcttacagtttcaacattactagtttaagtttgattgatttaaaagaattgtatagtatatttctattttgcttactaacaagttggtatatcaaacttaattttaagaaatctgtgcttagaattttaagataaaagactaagaggcaaatactttttgaaattggttttcattattgtacttcttgcgtagaattcctgatcttttatttatttattatttttaagttgttttgaattcaatgaccaggaaactcaaaatgacctttctattcctgcccttgctcactaactatatcatgaatgctaaatttggtctgccgttttctgtgatgtataagaatggctttaaaatgtcagtcccagcaaatgatataattgattttcatgtgaagaagagttgggagtttaatgtatattttggatagcaaatatgtccatgtgaagtgctgataggtgttattgtattacagtatcaagttactggcattgaggaccatacatttataacactgtagctgctatatttatttatgtagactctgatagttactgcactaaacaatgaggaaatgagcaccagtcaaggctagtgttagacacccctcctttttttcccc

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