LOCUS       XM_019726514            5576 bp    mRNA    linear   MAM 22-DEC-2016
DEFINITION  PREDICTED: Rhinolophus sinicus argonaute 3, RISC catalytic
            component (AGO3), transcript variant X5, mRNA.
ACCESSION   XM_019726514
VERSION     XM_019726514.1
DBLINK      BioProject: PRJNA358073
KEYWORDS    RefSeq.
SOURCE      Rhinolophus sinicus (Chinese rufous horseshoe bat)
  ORGANISM  Rhinolophus sinicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera;
            Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_017738966.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Rhinolophus sinicus Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5576
                     /organism="Rhinolophus sinicus"
                     /mol_type="mRNA"
                     /isolate="Zhonghua_01"
                     /db_xref="taxon:89399"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="muscle"
     gene            1..5576
                     /gene="AGO3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:109444829"
     CDS             192..2072
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X5"
                     /protein_id="XP_019582073.1"
                     /db_xref="GeneID:109444829"
                     /translation="

MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFNADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    192..533
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(327..329,372..374,414..416,426..428,480..482,
                     501..503,507..509)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    666..1943
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1077..1079,1089..1091,1125..1136,1143..1145,
                     1167..1169,1176..1178,1188..1190,1200..1202)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1281..1283,1287..1289,1497..1499,1911..1913)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gaatagatagaggagaaaaaactaatctgagaagccagttaggaggctttttcaatcactagttcaggtttcagtctacatgttacttccttgagaagcagtatttgacacccttcacccccccatccagccatcccccaagtctgatttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgagcaaccaagacctctgactgattcgcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacgagaaggcctgccagtcatcaaacctttcctttgcagttagaaaatggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaaacatacatacctgccactagaagtctgtaatattgtggcagggcaacgatgtatcaagaagctaacggacaatcagacttccactatgatcaaagcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaagttcgggatgaaatggcccatgtaaccggacgcgtacttccagcacctatgctccagtatggaggacggaatcgtacagtagcaacaccaagccatggagtgtgggacatgcgagggaaacaattccacacgggagtggaaatcaaaatgtgggccatagcttgttttgccacacagaggcagtgcagagaagaaatactgaagggtttcacggaccagctgcgtaagatttctaaagatgcggggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactctgggctgcagctcattatcgtcattctgccagggaagacgccagtgtatgcggaagtgaaacgtgtaggagatacacttttgggtatggctacacagtgtgttcaagtcaagaacgtaataaaaacatcccctcaaactctctcaaacttgtgcctaaagataaatgttaaactcggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcactcacccaccagctggtgatgggaagaagccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgccacagtaagagttcagagaccccgacaggagatcatccaggacttggcctccatggtccgagaacttctcattcaattttataagtcaactcgattcaaacctactcgtatcatcttttatcgggatggtgtttcagagggacagtttaggcaggtattatattatgaactactagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtggttcagaagagacatcacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagacattacacacccctatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgataactgctttaatgcagatgaacttcagctgctaacttaccagctctgccacacttatgtgcgctgtacacgatctgtttctatacctgcaccagcgtattatgctcacctggtggcattcagagccagatatcatctcgtagacaaagaacatgacagtgctgaaggaagtcacgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaaatgtccaaggatgttctcggagaggaagaactgaaagatgaatcgacatacaacctatgtttccagtggagtcagttaggtggtgatgcctgcagccatacagaaaccaacactgtggggaccagggtctgatttttatgttgatactaggaagattgtttacttcatgaagaaacacagcaccattatgcaatatgaaaccagccaactgcttttttgtgcaatctcctgtaggaagtgtcgccattgttttgttttcactttctcgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaaaaaaaaaaaggaaaggaaaggtaaatgatggtttttaaaaaaacatgcctacatgaataatcagagattgttcacaattacgtgtgcaaaaaaattaatgtgcattcgtgtattcttgtaaaaggtatctgtgtatattttaaatatatacatgtatacttcatatgcatatatatctggatctacactgataatagatatatatgttctttgtgtatgttttatagttcattccattggggaacttcctttcccttttattatcctcccaccaccacttttatttctctctctacctcccttgcctttatctcctatatttttttccctaatcctacaagtgacattcaaatgctcatgtatctggttcatttgaatatgaagcatgacaaactagactttcattttgcacacccactcctgtctcttttctcatacaccattctgagtcctcaattcttgatattgcttacttaagaaacaaagttactttatatatgtgtgtgtgtgtatacatacacacacacacatatgtgtgtatgtgtttttgtgagagtttgtgtttgccccctccagctctgaacttacatttgccatttgtgcaatgtgtacataagcagtagcaacctaaactattctttttctttagtgagtatgttaaagctgctataaatataaaacctgtcagaagtttaactttttctgtctataagtgatatgtattcaaaagacttctgtttctatggctctataagtgatatgtattcaaaagacttctgtttctatgggttatacatggagatcccttaaagcttttataaagggtaaatattttaaatgattggaactctgtagggttgaggcctctgaaattgggtagagagagagaaggggttattgaggtttttataattttttttttttttttgctaggttacttgctgcctctcataccttaatgtgattttcatatatatatatttttatatatatgtatgtgtgtatatataaacatatatgtatgtgttttgaagtatagcttccttttctatttattaggatagtgctttaataattatagaactgtattggcaacatcattgatggaaatataatcatgtttatttgaagaactgacaactggtttttgctgtcttttagtgcaataagcagttttaaaggaaagctgtgtctgtttgacgtctttaccacagatagtgggagaaacaggcacctccataattttaaaagagcaaagtaacaccgccttaatttcaaaaggaaagttttgtaattttcaaatctaaagcatgtctttaaaaatcataatgaaaatgaaggaagttaatatcctaaatgagactgaccataaatattaaaaataaagttgaactgtgatttaagaaatcaccatgaatagattaaaatttagaagatattaaaattcttcgaaaataaatcatgtttattgaaaaatcatactggttaggtacccattttcattaactaaaatgaattaggaaaatgtgatatattttttttaatttttgctaatttatcaccagtgactttccttttaaaattagggttatggtgacaaaggcagttaggactttgaacgttttaaatgagttaaatcactgaaatgtgggaaaaacttttggaaaacttttttttattattgacttcactttacggtattaaaaagtactatgaagctgtcaaaaccaagttcaccagtaacattggattcaggggagctttgcactttttaactcatgaaaattgcatttaaaatttttttttgcactggttcatagtataaatattacagattgtttccagtgggcattgttattagcctttcagaattccatctgctcatgaaaatgaatggattagctctatagttcctcttacctgtaatccagtcttattgccaatttactgtattttgagcctaaaacctgagcccatgtcctccaacaggtatgaaatcttttgtccctctgccagaaaactaagaaagtactgtattttgtatgtttattatattgaagtgtctgaaatgcaatttacaacactgtctcaaagttctttacatgagataatatttatatagtatgtacattttttctcccaactctccctcctcctccaaaaaatttctgttatatatatatgattttgtttttttacgttgaaacttcactgaatacagtagtcaggaacatggacaagagaagaaaatggtgtgtcctagatggtaaaaacttgattgctgtgtgcttgttcagtgtgagtaaaacatcttcctttatctgtgggagttgcagtttcatgtgggaaactttaggacccagggaagagctgtagatacactttccctatttactgctttacctaattttcagttacttattttcacctgcgctagactgaagcccgtaatttaaatctatttggaaggacttttacagaggaaaaagaaaaaaattttaatataaagctttacctttgaagtgagttctttttttagggtttctttcttacagtttcaacattactagtttaagtttgattgatttaaaagaattgtatagtatatttctattttgcttactaacaagttggtatatcaaacttaattttaagaaatctgtgcttagaattttaagataaaagactaagaggcaaatactttttgaaattggttttcattattgtacttcttgcgtagaattcctgatcttttatttatttattatttttaagttgttttgaattcaatgaccaggaaactcaaaatgacctttctattcctgcccttgctcactaactatatcatgaatgctaaatttggtctgccgttttctgtgatgtataagaatggctttaaaatgtcagtcccagcaaatgatataattgattttcatgtgaagaagagttgggagtttaatgtatattttggatagcaaatatgtccatgtgaagtgctgataggtgttattgtattacagtatcaagttactggcattgaggaccatacatttataacactgtagctgctatatttatttatgtagactctgatagttactgcactaaacaatgaggaaatgagcaccagtcaaggctagtgttagacacccctcctttttttcccc

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