LOCUS       XM_019726513            5726 bp    mRNA    linear   MAM 22-DEC-2016
DEFINITION  PREDICTED: Rhinolophus sinicus argonaute 3, RISC catalytic
            component (AGO3), transcript variant X4, mRNA.
ACCESSION   XM_019726513
VERSION     XM_019726513.1
DBLINK      BioProject: PRJNA358073
KEYWORDS    RefSeq.
SOURCE      Rhinolophus sinicus (Chinese rufous horseshoe bat)
  ORGANISM  Rhinolophus sinicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera;
            Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_017738966.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Rhinolophus sinicus Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5726
                     /organism="Rhinolophus sinicus"
                     /mol_type="mRNA"
                     /isolate="Zhonghua_01"
                     /db_xref="taxon:89399"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="muscle"
     gene            1..5726
                     /gene="AGO3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:109444829"
     CDS             93..2222
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X4"
                     /protein_id="XP_019582072.1"
                     /db_xref="GeneID:109444829"
                     /translation="

MLLYLGKVEKIDLSRCQSNLCLGYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFNADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    168..320
                     /gene="AGO3"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    321..683
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(477..479,522..524,564..566,576..578,630..632,
                     651..653,657..659)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    816..2093
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1227..1229,1239..1241,1275..1286,1293..1295,
                     1317..1319,1326..1328,1338..1340,1350..1352)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1431..1433,1437..1439,1647..1649,2061..2063)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

tatatttggggactgtagaccagtttatgatggaaaaagaagcctttacacagccaatccacttcctgtggcaactactggggtagatttagatgttactttacctggggaaggtggaaaagatcgacctttcaaggtgtcaatcaaatttgtgtctcggatatacgccggtggggcgttcctttttctcagctccagaaggatatgaccaccctctgggagggggcagggaagtatggtttggattccatcaatctgttcggcctgcgatgtggaaaatgatgcttaatattgatgtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgagcaaccaagacctctgactgattcgcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacgagaaggcctgccagtcatcaaacctttcctttgcagttagaaaatggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaaacatacatacctgccactagaagtctgtaatattgtggcagggcaacgatgtatcaagaagctaacggacaatcagacttccactatgatcaaagcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaagttcgggatgaaatggcccatgtaaccggacgcgtacttccagcacctatgctccagtatggaggacggaatcgtacagtagcaacaccaagccatggagtgtgggacatgcgagggaaacaattccacacgggagtggaaatcaaaatgtgggccatagcttgttttgccacacagaggcagtgcagagaagaaatactgaagggtttcacggaccagctgcgtaagatttctaaagatgcggggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactctgggctgcagctcattatcgtcattctgccagggaagacgccagtgtatgcggaagtgaaacgtgtaggagatacacttttgggtatggctacacagtgtgttcaagtcaagaacgtaataaaaacatcccctcaaactctctcaaacttgtgcctaaagataaatgttaaactcggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcactcacccaccagctggtgatgggaagaagccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgccacagtaagagttcagagaccccgacaggagatcatccaggacttggcctccatggtccgagaacttctcattcaattttataagtcaactcgattcaaacctactcgtatcatcttttatcgggatggtgtttcagagggacagtttaggcaggtattatattatgaactactagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtggttcagaagagacatcacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagacattacacacccctatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgataactgctttaatgcagatgaacttcagctgctaacttaccagctctgccacacttatgtgcgctgtacacgatctgtttctatacctgcaccagcgtattatgctcacctggtggcattcagagccagatatcatctcgtagacaaagaacatgacagtgctgaaggaagtcacgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaaatgtccaaggatgttctcggagaggaagaactgaaagatgaatcgacatacaacctatgtttccagtggagtcagttaggtggtgatgcctgcagccatacagaaaccaacactgtggggaccagggtctgatttttatgttgatactaggaagattgtttacttcatgaagaaacacagcaccattatgcaatatgaaaccagccaactgcttttttgtgcaatctcctgtaggaagtgtcgccattgttttgttttcactttctcgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaaaaaaaaaaaggaaaggaaaggtaaatgatggtttttaaaaaaacatgcctacatgaataatcagagattgttcacaattacgtgtgcaaaaaaattaatgtgcattcgtgtattcttgtaaaaggtatctgtgtatattttaaatatatacatgtatacttcatatgcatatatatctggatctacactgataatagatatatatgttctttgtgtatgttttatagttcattccattggggaacttcctttcccttttattatcctcccaccaccacttttatttctctctctacctcccttgcctttatctcctatatttttttccctaatcctacaagtgacattcaaatgctcatgtatctggttcatttgaatatgaagcatgacaaactagactttcattttgcacacccactcctgtctcttttctcatacaccattctgagtcctcaattcttgatattgcttacttaagaaacaaagttactttatatatgtgtgtgtgtgtatacatacacacacacacatatgtgtgtatgtgtttttgtgagagtttgtgtttgccccctccagctctgaacttacatttgccatttgtgcaatgtgtacataagcagtagcaacctaaactattctttttctttagtgagtatgttaaagctgctataaatataaaacctgtcagaagtttaactttttctgtctataagtgatatgtattcaaaagacttctgtttctatggctctataagtgatatgtattcaaaagacttctgtttctatgggttatacatggagatcccttaaagcttttataaagggtaaatattttaaatgattggaactctgtagggttgaggcctctgaaattgggtagagagagagaaggggttattgaggtttttataattttttttttttttttgctaggttacttgctgcctctcataccttaatgtgattttcatatatatatatttttatatatatgtatgtgtgtatatataaacatatatgtatgtgttttgaagtatagcttccttttctatttattaggatagtgctttaataattatagaactgtattggcaacatcattgatggaaatataatcatgtttatttgaagaactgacaactggtttttgctgtcttttagtgcaataagcagttttaaaggaaagctgtgtctgtttgacgtctttaccacagatagtgggagaaacaggcacctccataattttaaaagagcaaagtaacaccgccttaatttcaaaaggaaagttttgtaattttcaaatctaaagcatgtctttaaaaatcataatgaaaatgaaggaagttaatatcctaaatgagactgaccataaatattaaaaataaagttgaactgtgatttaagaaatcaccatgaatagattaaaatttagaagatattaaaattcttcgaaaataaatcatgtttattgaaaaatcatactggttaggtacccattttcattaactaaaatgaattaggaaaatgtgatatattttttttaatttttgctaatttatcaccagtgactttccttttaaaattagggttatggtgacaaaggcagttaggactttgaacgttttaaatgagttaaatcactgaaatgtgggaaaaacttttggaaaacttttttttattattgacttcactttacggtattaaaaagtactatgaagctgtcaaaaccaagttcaccagtaacattggattcaggggagctttgcactttttaactcatgaaaattgcatttaaaatttttttttgcactggttcatagtataaatattacagattgtttccagtgggcattgttattagcctttcagaattccatctgctcatgaaaatgaatggattagctctatagttcctcttacctgtaatccagtcttattgccaatttactgtattttgagcctaaaacctgagcccatgtcctccaacaggtatgaaatcttttgtccctctgccagaaaactaagaaagtactgtattttgtatgtttattatattgaagtgtctgaaatgcaatttacaacactgtctcaaagttctttacatgagataatatttatatagtatgtacattttttctcccaactctccctcctcctccaaaaaatttctgttatatatatatgattttgtttttttacgttgaaacttcactgaatacagtagtcaggaacatggacaagagaagaaaatggtgtgtcctagatggtaaaaacttgattgctgtgtgcttgttcagtgtgagtaaaacatcttcctttatctgtgggagttgcagtttcatgtgggaaactttaggacccagggaagagctgtagatacactttccctatttactgctttacctaattttcagttacttattttcacctgcgctagactgaagcccgtaatttaaatctatttggaaggacttttacagaggaaaaagaaaaaaattttaatataaagctttacctttgaagtgagttctttttttagggtttctttcttacagtttcaacattactagtttaagtttgattgatttaaaagaattgtatagtatatttctattttgcttactaacaagttggtatatcaaacttaattttaagaaatctgtgcttagaattttaagataaaagactaagaggcaaatactttttgaaattggttttcattattgtacttcttgcgtagaattcctgatcttttatttatttattatttttaagttgttttgaattcaatgaccaggaaactcaaaatgacctttctattcctgcccttgctcactaactatatcatgaatgctaaatttggtctgccgttttctgtgatgtataagaatggctttaaaatgtcagtcccagcaaatgatataattgattttcatgtgaagaagagttgggagtttaatgtatattttggatagcaaatatgtccatgtgaagtgctgataggtgttattgtattacagtatcaagttactggcattgaggaccatacatttataacactgtagctgctatatttatttatgtagactctgatagttactgcactaaacaatgaggaaatgagcaccagtcaaggctagtgttagacacccctcctttttttcccc

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