LOCUS       XM_012957369            6518 bp    mRNA    linear   VRT 18-DEC-2019
DEFINITION  PREDICTED: Xenopus tropicalis argonaute 4, RISC catalytic component
            (ago4), transcript variant X5, mRNA.
ACCESSION   XM_012957369
VERSION     XM_012957369.3
DBLINK      BioProject: PRJNA205740
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_030678.2) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 18, 2019 this sequence version replaced XM_012957369.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Xenopus tropicalis Annotation
                                           Release 104
            Annotation Version          :: 104
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.3
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6518
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /strain="Nigerian"
                     /db_xref="taxon:8364"
                     /chromosome="2"
                     /sex="female"
                     /tissue_type="liver and blood"
                     /dev_stage="adult"
                     /note="F17 inbred"
     gene            1..6518
                     /gene="ago4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 24 ESTs, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 52 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:100495218"
                     /db_xref="Xenbase:XB-GENE-1006882"
     CDS             19..2658
                     /gene="ago4"
                     /codon_start=1
                     /product="protein argonaute-4 isoform X5"
                     /protein_id="XP_012812823.1"
                     /db_xref="GeneID:100495218"
                     /db_xref="Xenbase:XB-GENE-1006882"
                     /translation="

MEAVGPGESEIGEGGSKAEANGPPPTNLFQPPRRPGLGTLGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMPIFGDRQPGYDGKRNMYTAHPLPIGRDRVDLEVTLPGEGKDQTFKVTIQWVSVVSLQLLLEALAGHLSEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPVIEFMCEVLDVQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRVSNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKLTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQETTQELLYSQEVIQDLSNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELMAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA"

     misc_feature    19..2652
                     /gene="ago4"
                     /note="protein argonaute; Provisional; Region: PLN03202"
                     /db_xref="CDD:215631"
     misc_feature    1216..2529
                     /gene="ago4"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1633..1635,1645..1647,1681..1692,1699..1701,
                     1723..1725,1732..1734,1744..1746,1756..1758)
                     /gene="ago4"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1837..1839,1843..1845,2083..2085,2497..2499)
                     /gene="ago4"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gagaggacagcagcggagatggaggcggtggggcctggtgagtcggagattggtgagggggggagcaaagcggaagcaaatggccctccaccgacgaacctcttccagcctccgcggcgtcctggactgggaacgctgggaaagccaattcggctactggccaatcattttcaggttcagatcccgaagatagatgtctaccattatgatgtggacatcaaaccagagaaaaggccaaggagagtcaacagggaggtggtggatacaatggtgcgtcatttcaagatgccgatttttggagatcgccagccaggttatgatggcaaaaggaacatgtacactgctcaccctctaccaattggcagggacagagttgatttggaagtgacccttcctggtgaaggtaaagaccagacattcaaagtcactattcagtgggtctctgtggtgagccttcagcttcttttagaggctttagctggacatctaagtgaagtaccggatgattctgttcaggctcttgatgtaatcactcgccatctaccatccatgaggtatacaccagttggtcggtctttcttctctcctcctgaaggttattatcacccactcggtggtgggcgagaagtatggtttggctttcaccagtctgttcgtccagccatgtggaacatgatgctcaatatagatgtttctgcgactgccttttaccgtgctcagccggtcatagaatttatgtgtgaagtcctagacgtgcagaacatcaatgaacaaacaaagcctttgactgattcacagcgtgtcaagttcaccaaagaaataagaggtctgaaagttgaagtgacgcactgtggacaaatgaaaagaaagtacagggtgtgcaatgttactagaagaccagcaagccaccagacgtttcctttgcagttggagaatggtcaagccatggagtgtaccgttgctcagtattttaagcagaaatatagcttacagttaaaatatccacatctcccttgtctgcaagtgggacaggagcagaaacacacatacttgccacttgaggtttgcaacattgtagctggacagcgatgtattaagaaactgacagacaatcagacttccaccatgatcaaagctacagctcgatctgctccagacagacaggaggagatcagcaggctggtgaagagtaacagtatggtcggtggaccagatccataccttaaggagtttggtattgttgttcataatgaaatgacagagctaacaggcagagtcttgccagcaccaatgcttcagtatggcggaagagtgagtaataaaactgtagccacaccaaaccagggtgtttgggacatgagaggaaagcagttctacgctggtattgagatcaaagtttgggctgttgcttgttttgcaccacaaaagcagtgcagagaagacttgttaaaaagtttcactgatcagttgagaaagatctccaaagatgcagggatgcccattcaaggtcagccttgcttctgtaaatatgcccaaggtgcggacagtgtggagccaatgttcaaacatctgaagttgacatatgttggtcttcaacttattgtggtgattttgcctggcaagaccccagtttatgcggaggtgaaacgagtaggggacacactacttggtatggccactcagtgtgttcaggtgaaaaatgtagtcaagacttctcctcagacactatcaaacctctgcctgaaaatcaatgccaagctggggggaattaacaacgtgttggttcctcaccaaagaccttcagtgtttcaacagcctgttatatttctgggagcagatgtaacacacccccctgctggggatggcaagaaaccttccattgcagctgtagtgggcagcatggatgggcatcccagccgctactgtgccactgtgcgtgttcagacctcgcgccaagagacaacccaagagctgctgtacagccaggaagttattcaagaccttagcaacatggttcgggaactgcttattcagttctacaagtcaactcggttcaaacccactagaattatctattatagaggaggtgtttctgaaggtcaaatgaaacaggtggcatggcctgagcttatggctattcgaaaggcctgcatcagcttggaagaagattacaggcctggaataacatacattgttgtacaaaaaaggcatcatacaaggcttttttgcgctgacaaaacagaaagggttggaaagagtggcaatgtgccagcaggaactactgttgacagcacaataacacatccatcagagtttgatttctatctctgtagtcatgctgggattcagggaacaagtcgtccatctcattaccaggttctctgggatgataactgcttcactgctgatgaactccaactgcttacctaccagctgtgtcacacatatgtgcgttgcacacgatctgtttcgatccctgcccctgcctactatgctcgactcgttgcatttagagcaaggtatcatcttgtggataaggatcacgacagtgctgaaggaagccatgtatctggtcagagcaatggtcgagatcctcaggctctggccaaagctgttcagattcaccacgacacacagcacacaatgtactttgcctgacagcacagtgagagctggcacaaactctcctcatccttcttttccaatccctgaaatctgttaagcagacttccctgtaatgttcagggccagttctgtctcttggcttcccaccagcacattttggactttttgcactgaatctctttatgatggcatttgaatggaggaaagatgcaaacatttttatttagttatgtaaaaaaacttatggattgtcttctgatgcattggactgaatatttacctcaagctcaaaagatatctgaacattttactccaagcaactcttgttgtgttaattatttttaatttgcaagccagcatttcatcatccttggttgtaacaaaaatgtacatgcttttttgtctcaacatgctgctttgcgactgtacttaaacggaaaagtgtaactgagtggggccatagacttgctaaatgaggtttagtccttactgtaaaataccttcttaatgtttttacaggtaatgccgtctgtcaggtttcttaaccattgcaaacttgtactttttaatgagtgcaggctgcaaatctattgcactatattgcatattaattaaggtaagtttttatttctgtataaaatgaatgtgtaatattaagatttaatataagggccatgtggcgagcactgccatataatttttcacatgcagattgccattactcttccttccccagacaccttttgctgcccaaaacatgttagtattttgccagcacacacagatgcccgtgttattgctgctgcagtttgataaagtttttactctcgaagggatggggtgtggggtaccattttatggcaataacacatttttagtatcatttactatcatttcggcatccacatggtttctgggtgttgtatgatgtagacgttgtctcctttcattaccagtgaatttgtggggaatctgttttacaaaattaccttctcactcttaaggtttttctctgctggttttttttgagcatgtttttttttctgtctatgtgatgtagattgttacttccagtatagcctatgacctctattgttggcagagaatccttcattgccagcagggcaggccctgcatttacaaagaattaaagctccttgactgttgggagagatttaggcagctttgggcccgctgagactacacgatttataccagcattttctattcgtgttggttctctggacccagactaacaaagtgcatgtttgtataatctgcatgtacaacattttcttattatgcctttattcagtttattatttttatgaatgaaaaccaacccatttctgtatacacatgctcttacctgtcctccttgatccctccactctaaaaggttcttgagataaacctttgcagtgctcaactacctgcaggttttgtgatgtggcaactccattaactttaacaagccctgtcttttgtttctctggtatacctcagttgcatttactgctttttttcctgctctaattatccatgttcttacagcatgacaacaggtttgaccattgattttctttttcttctctccatatctacacagaatatacctcactgggacagtagaagttgtgaatgggagggttattgtgctgctttgggctttattgctgcttggtaacccactttagtgccaggaggacctcctgaaggtgctaaggttgtaatcttttgtatgtagtgtgtttgcagttgcagcttggtgagaatctccatatgaccttgatagctttgctgtgtttactggtgattatttcttcagcagttccatttccccagattataactggtgacacatagggctgtttttatgggtcatgccatttgttggcccactgtttattatatgtatattgtgtaactagaccaaaacattgattggctcacatcagaagagcagtcccatgctatctctgatttgctgcatacatagccagccaggatttctgttttcagtgactaactctctaatcatttcaggtatgaggtatgttctaagtactcattcagaggtatttttttaaaataattgcccaatttggttaaaattataattgccgggcctgatctagcttaggagtaagtttattaccaaaggcaagtttcttggctatcttaggagatatcaggcagctatgagctacagtcccaagcaattgaggcttcttggaaaggtttagtttagataccctgttaggcttaaaacttagctcaattgggtttaactagcaagtttgagtatttcatgtgactgacagacaatgacatcatctaatgtaaagtacagggcaaatctagtactgaaacatccaaaatgaacaataatatgaatttgtggtcatttctgtattaaaactataaaatgttaatgccaatgaaatttagaagtccactgtaggaaatgttatgtagtgaaaaaatgcagacctacgtagcaccatttatgcaatatgtgaaaaaaacagaaggctattgcttttcactcccatagcattaagagttttaagcccctttgggttgcgatcatcaacagtgttttctattacggcttacacaataagcaacaagataactgtgccatgagcttcagtatgcagccgactttattgccgtgtcgagctttggccactcgtgactattaaagggtcagctacacacttgtatatagatataaaactgagccaggatacctacagcagtggagatctgtacagttttgaaagtatgattatgtctttgttaggaccgcaatatcagatgaggttttttttgtttttttttcattttgtttgatttctggttaaggataaagggacatgggtgggtgggaaggtagcattaagtagaagtggggtatgtgttttgtaaacttttgaaacactgcacaatttgtgttgcagcaatactattgtgaactttttttttttgttttttttttctcttttccctagtaaatagcagggggtgtgcttggatcagtgttttggggaaaattcgtacctgttttaagaggtttgagtagctgttgcatattttcagtttctctcttatgagactttttaaagggaatctgttatgaatgttcaggaatttgtaaaataatttggtgacatttttcaacttttactaaattgtacaccctaatcggtgtttctcaaatatgtattttccgttcttactggcaattaaattttttttttactggttctcaaaagaattctaagtcccaatgagaactctagacttgtccagttacagcctttctatacacagtcaacccattacttgtttgtaagtgtaaaagaaaaatttatgctttaaaattgcccgttattgaaactttgtataccatacggggaaatgaggggtgttggtcattttgcaccaaagtaaagaaattacagattttagatgttaatactgcagtctgaaaatgcatagttgttttttcaagttaactggcatcctaattacaagactatattgaaaaaagcatttcatatttagagtgatggatctgaagatttaaaggctatatccaggtagataccagactgctgactggtaggacagtctgtgtgttcttatgattggcccttcattaagcggtagtaattcagaatctgtgtttaaactttgcttcagataagtgaatcaaggtcaagtgagagttgtaggcctctaaccatgcttgtaagagcacttggtgtattaaacccgcactttggcatagcctatgaatacaacagcctgcctagtatgaaggggtttatttgcagagtattctcaaggtaagtttggtctgtgtagatagttgtagcataaga

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