LOCUS       NM_001079246            3325 bp    mRNA    linear   VRT 27-JUN-2020
DEFINITION  Xenopus tropicalis GTP binding protein 2 (gtpbp2), mRNA.
ACCESSION   NM_001079246
VERSION     NM_001079246.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 3325)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC125670.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC125670.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3325
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="5"
                     /map="5"
     gene            1..3325
                     /gene="gtpbp2"
                     /note="GTP binding protein 2"
                     /db_xref="GeneID:780171"
                     /db_xref="Xenbase:XB-GENE-996416"
     exon            1..284
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    81..83
                     /gene="gtpbp2"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     MPALGIPCQAGGGAGRRAGG"
     CDS             141..1895
                     /gene="gtpbp2"
                     /codon_start=1
                     /product="GTP-binding protein 2"
                     /protein_id="NP_001072714.1"
                     /db_xref="GeneID:780171"
                     /db_xref="Xenbase:XB-GENE-996416"
                     /translation="

MEPRVFELFGPAGGSGGTGARGKTKGKKAGKGRGRSSKSNNPPYLPPEAEEGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLSEEEMKASLHTLHRMAEKVGADITVLREREVDYDSDSPRKITEVLIRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVINYSESRTAEQICESASKMITFIDLAGHHKYLKTTIFGLTSYCPDFAMLVVSANTGIAGTTREHLGLAMALKVPFFLVVSKVDLCAAATVERTLRQLERTLKQPGCNKVPFMVRSEDDAVTAAQQFAQSPNITPIFAISSVTGESLDLLKVFLNILPPLTNSHEQEELMQQLPEFQVDEIYTVPEVGTVVGGTLYSGVCKEGEHLVVGPTDGGGFLPLKVCSIQRNRSTCRVLRAGQAATLALGEFERSLLRKGMVLVSPEALPTVCWVFEAEIVLLFHATSCRQGVQVTVHVGNVRQTAVLEHIHGKDELRTGEKAVVRFRFIKHPEYLKPGTKLLFREGMTKGIGHVCSLQVIATAIGDP"

     misc_feature    618..1280
                     /gene="gtpbp2"
                     /note="GTP binding protein 1 (GTPBP1)-like family includes
                     GTPBP2; Region: GTPBP1_like; cd04165"
                     /db_xref="CDD:206728"
     misc_feature    633..656
                     /gene="gtpbp2"
                     /note="G1 box; other site"
                     /db_xref="CDD:206728"
     misc_feature    order(642..659,1044..1049,1053..1055,1221..1229)
                     /gene="gtpbp2"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206728"
     misc_feature    order(678..704,708..785)
                     /gene="gtpbp2"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206728"
     misc_feature    756..758
                     /gene="gtpbp2"
                     /note="G2 box; other site"
                     /db_xref="CDD:206728"
     misc_feature    order(873..926,933..944)
                     /gene="gtpbp2"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206728"
     misc_feature    876..887
                     /gene="gtpbp2"
                     /note="G3 box; other site"
                     /db_xref="CDD:206728"
     misc_feature    1044..1055
                     /gene="gtpbp2"
                     /note="G4 box; other site"
                     /db_xref="CDD:206728"
     misc_feature    1221..1229
                     /gene="gtpbp2"
                     /note="G5 box; other site"
                     /db_xref="CDD:206728"
     misc_feature    1323..1583
                     /gene="gtpbp2"
                     /note="Domain II of the GTPBP family of GTP binding
                     proteins; Region: GTPBP_II; cd03694"
                     /db_xref="CDD:293895"
     misc_feature    1599..1862
                     /gene="gtpbp2"
                     /note="Domain III of the GP-1 family of GTPases; Region:
                     GTPBP_III; cd03708"
                     /db_xref="CDD:294007"
     exon            285..311
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            312..496
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            497..605
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            606..803
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            804..978
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1198
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1334
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1393
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1565
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1730
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1731..3241
                     /gene="gtpbp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gaagcggccggctgggcagtggggcagagtggggcagcgggctgtgcggcgctttcctaggctggtacctccggagcctcatgcccgccctgggcattccgtgccaggcagggggaggagcgggccgcagggccggcgggatggagccgcgggtgtttgagctgttcgggccggcaggaggcagcggtgggaccggagcccgggggaaaacgaaagggaagaaagcggggaagggccgagggcggagtagcaaaagcaacaaccctccctacctacccccggaggcagaagaagggaatattgagtataagctgaagctggtgaacccgtctcagtaccgctttgagcatttggtgacgcagatgaaatggcgcctgcaggagggccggggcgaggcggtgtaccaaataggggtggaggataacggcctgttggtggggctgtcggaggaggagatgaaagcctcactgcacaccctgcaccgtatggcagagaaggtgggcgctgacatcacggttctgcgcgagcgagaggtggattatgacagcgactccccgaggaagataacggaggttctgatccgcaaggtccctgacaaccagcagttcctggacttgcgggtcgcggtactggggaacgtggactcggggaagtctacgctgctgggggtcctgacgcagggagagttggacaacgggcggggccgggcccggctcaacctcttccgccacctccatgagatccaatcgggtcggacttccagcatcagctttgagatcctgggcttcaatagcaaaggggaggtgataaattacagcgagtcgcgcacggcggagcagatctgtgagagcgcctccaaaatgatcacgttcatcgacctcgccgggcaccacaagtacctgaaaaccacgatctttggcctgactagctactgccccgacttcgccatgctggttgtgagcgccaacacgggcattgcgggcacaacgcgggagcacctgggcctggccatggcactcaaggttcccttctttctggtggtcagtaaggtggatctgtgtgccgcggccacggtggagcgcaccctccggcagctggagcgcaccctgaaacagcccgggtgcaacaaggtgccctttatggtgcgctcggaggatgatgcagtaacggcagcgcagcagtttgcccagtcgcccaacatcacccccatctttgccatctccagtgtcactggggagtccctggatctactcaaagtcttcctgaatattctgccccccctcaccaacagccacgagcaggaagagctgatgcagcagctgcctgagttccaggtggatgaaatctacaccgtgccggaggtggggactgtggtgggcgggaccttgtacagtggggtgtgcaaggagggggagcacctggtcgtcggccccacagatggggggggtttcttgcccctgaaagtctgcagcatccagaggaaccgatccacgtgccgcgtcctccgcgcgggtcaggcggccacattggcgctgggggagtttgagcgctcgctgctccgcaaggggatggtgctggtgagcccggaggcgctgcccacggtatgttgggtgtttgaggcggagattgtgctgctgttccacgccacgtcctgccggcaaggggtgcaggtcacggtgcacgtggggaacgtccgacagacggccgtgttggagcacattcatggcaaggatgagctgcggacgggggagaaggcagtcgttcgcttccgcttcattaaacaccctgagtacctgaagccgggcaccaagctcctgttccgcgagggcatgaccaagggcatcgggcacgtgtgcagcctgcaggtgattgcgacggccattggcgacccttgatctcctgcggttggacccatggggcgctgggctccacaggcacccaatcagaagccagggaaggcggggccggcccgaggagccatatagactggcattggtcagatcctgccccaagctcacccattggacgaagcagctgatttataattcccttcgcccgcgtcgcttttatgccgaaaaatgacttttatacgagaaaaagaaaccgttttacatgtatttttatgattcccgataaaaaccttttattagtggaatttgcggagtcaccggatcccaatgggaagttttagtgcaattttactggggaatttccagtgtatcattggggcaataacccaactgcccctcattgtgccccttggcacccactgtctgggcttctacataagcacccacattggggtgaaactgggacccccagctgctcccctgtaccccctgcacttgggagggtgggtagagttttggggcaaaacaggtgagtactgggggcaaactgggttcacttacccaggggcaagaattagggcccccaggggcagtctctctctgtctatatttgctcatttacaaattcccagaaatccctttgatttactgaaccactttgtaatttaccccggtcagttaccccttggcgggtatcttggccccgggccttctgcttttacctaagagtgtagagaaagcagccaatgagagaaacccataacgcacaactgattggaggaaaccctaatgcccagccaatcagcctgaaggaaaaaatctttcccccaaaccaactttttcattttatttttgtcgggcacaagaggtaaataaaacgaggtaactgctgcccccccaacccccccccccccccccccggtgctgagaaggggcaggaatgggaaaactaatgggggttcagcagccagagaagtgcagagatttgattggtagagagaccctgcgctccctattggctcattgcttgatccaaagcaactgtcccacagccaatggggtaactgtgtgacacctgttcaatgtaaggggcgtggccaattcaggatcagggcgggtgctaaccctgcacccaatcagcctgtggcccacctagtgcctttcctccagcagggggcgccaggggtgccgctgatacagaccttgcacaatggtgtcgattctcccctgtatatcagctcttgggccgagctctcgccattctctctgcccccccccaaactctgctgcttctcttcttcttcttgtgcagctttatattggggggccctgtgtgtccccaaaatttctctctctgcatgtcacctacacaataaaatgttttatggaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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