LOCUS       NM_001079153            3780 bp    mRNA    linear   VRT 02-FEB-2024
DEFINITION  Xenopus tropicalis 2-phosphoxylose phosphatase 1 (pxylp1), mRNA.
ACCESSION   NM_001079153
VERSION     NM_001079153.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 3780)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC123016.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC123016.1, CX913378.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3780
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="5"
                     /map="5"
     gene            1..3780
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="2-phosphoxylose phosphatase 1"
                     /db_xref="GeneID:780077"
                     /db_xref="Xenbase:XB-GENE-979576"
     exon            1..36
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /inference="alignment:Splign:2.1.0"
     exon            37..169
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    64..66
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="upstream in-frame stop codon"
     CDS             91..1596
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /EC_number="3.1.3.2"
                     /note="acid phosphatase-like protein 2; acid
                     phosphatase-like 2"
                     /codon_start=1
                     /product="2-phosphoxylose phosphatase 1"
                     /protein_id="NP_001072621.1"
                     /db_xref="GeneID:780077"
                     /db_xref="Xenbase:XB-GENE-979576"
                     /translation="

MLLRNRFLLLLALAGLLAFLSLSLQFFSRWLPVSLQLKTEMQVFPEFPVRLIQVGQGREEGLGAKNRKRIMPEPLTEPPALNPLYEANLYCNTPGAKERSMEGHAPPNLKLLSVQVIIRHGDRYPLYTIPKTKRPDIDCVLEPGRKPSHPHLTDFISHMSKGVDTQMDGTLGSLPRLPNHILCEMGELTQTGVVQHLRNGQLLKEIYLKKHRLLTSAWTAKHLYFESTGKSRTLQSGLALLYSLLPNFDWKKINVKHQWSTIFCSNHCDCPMRNHYLEEEQRRQYNFRVKNSLLEKTYINMAKIVGIPTRQLRASNPIDSLLCNFCHNATFPCTKNGCIDLEHFKVIKTHQLEDEKERYEKQLYFKYALMATHPLLNQTANRMLRIAEGKKDELFALYSAHDVTLSPILSALGLREARFPRFAARLVFELWHDPEKANNHYVRVLYNGEDVTFQTSFCRDQLRSSKRPLCPLKKFSTFVQKDMFSSLNSTSYYDACHQRLF"

     misc_feature    109..171
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q0IHQ9.1);
                     transmembrane region"
     misc_feature    418..1431
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="Histidine phosphatase domain found in a
                     functionally diverse set of proteins, mostly phosphatases;
                     contains a His residue which is phosphorylated during the
                     reaction; Region: HP; cl11399"
                     /db_xref="CDD:472174"
     misc_feature    order(445..450,457..459,784..786,1291..1296)
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="catalytic core [active]"
                     /db_xref="CDD:132717"
     misc_feature    1072..1074
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
                     from UniProtKB/Swiss-Prot (Q0IHQ9.1); glycosylation site"
     misc_feature    1219..1221
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
                     from UniProtKB/Swiss-Prot (Q0IHQ9.1); glycosylation site"
     misc_feature    1552..1554
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
                     from UniProtKB/Swiss-Prot (Q0IHQ9.1); glycosylation site"
     exon            170..226
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /inference="alignment:Splign:2.1.0"
     exon            227..397
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /inference="alignment:Splign:2.1.0"
     exon            398..524
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /inference="alignment:Splign:2.1.0"
     exon            525..664
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /inference="alignment:Splign:2.1.0"
     exon            665..3766
                     /gene="pxylp1"
                     /gene_synonym="acpl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctcagggatcatcgggctcactgatcagactgccaggaatgttcagggattgcactgaaaacatgaagaaaaagtagaagacacagaagaatgcttctccgaaaccgatttctcttactgctggccttagctggactgctggcctttctaagcctcagcctgcaattcttttccagatggttgcctgtcagtctgcagcttaagactgaaatgcaggtgtttccagagttcccggtgcgtctgatccaagttggtcaaggcagagaggaaggtctgggtgccaaaaaccggaaaagaatcatgcctgagcctttgacagagccacctgcattaaatccactctatgaagcaaatctctattgcaatactccgggagccaaagaaagaagcatggaaggccatgctcctcccaatttaaagttgttgtctgtacaagtaattatccggcatggagacaggtatccattatataccattcccaaaaccaagagacctgatattgactgtgtacttgaaccaggcaggaaaccatctcatcctcatttgacagatttcattagccatatgtcaaaaggagtagacacacaaatggatggcaccttgggcagcttgcctcgcttacccaaccacattctgtgtgaaatgggagagctgactcagacaggtgtagtgcaacatctcagaaatgggcagctgctgaaggaaatctacttgaagaaacaccgactcctaacgagtgcatggactgcaaagcatctctatttcgaatccactggaaaaagtaggacattgcaaagtgggctggccctgctttacagccttctgcctaattttgactggaagaaaataaatgttaagcaccaatggagtacaatattttgctctaaccactgtgactgcccaatgaggaaccattatctagaagaagaacagcgtcgccagtacaattttcgagtgaagaacagcctcctagagaagacctacataaatatggccaaaatagtaggtatccccactaggcagttaagggcctcaaaccctatagactcattactgtgtaatttctgccacaatgcaacctttccttgcaccaaaaatggctgcattgacttggagcactttaaagtcatcaagacacatcaactggaagatgaaaaagaaagatatgaaaagcaactttatttcaaatatgcactgatggcaacccatcctcttttgaaccagacggccaacagaatgctccgtattgcagaaggcaaaaaggatgagctttttgctttgtactctgcccatgatgtgaccctctcccctatattgagtgctttgggtctcagagaagccagattcccaagatttgctgctcgcttagtttttgaactgtggcacgacccagagaaagcaaacaatcactatgtgagggtactgtataacggggaagatgttacgtttcagacctctttctgccgagatcagctaaggagttcaaagcgtcccctgtgcccgcttaaaaaatttagcacttttgtccagaaagatatgttttcatcccttaatagcacaagctactatgatgcttgccatcagcggctattttgaaatttttagaatgtaaagaacaatttgactggtcttggtaatttcttgtcggtaacatcagcattaggtactctctcctttctgccatggtttcataaaaatggaacttatttagtgtggtttttgtttaatttcccttaattggccttaaaaagtatggcggcattgctaaacatgttcactgaacaccctgctctgcatatctgtttttttacatgagtgggagtttccttattgcttaactcagaggcacctgtatgttcaaaacagttttactgctctagtggaaaatgactgacaatttaattaacatggcagctccctataatgtaatgcaatgcagatatacagttatggtttgctttcatacttaattggctgttaaaaagaaaactgggtatgttttaactttactacagttctgttctgtatcattgctgtgttgacagcaaacaccatcagtatgctgttacatcactaatatggctgctatactgtattgtcctgatctagagaccgtgtcagttacatgactatcccttttagtctggttgcagactataccagcaatgcttgatccaaacacccagttcagacgccaaatatctgttttgttcctataaacttattgaaaagctattttaaataagcaaggaaattgtttaatatttggatgaaggaaggtttgccatcctagatagtacaacttcccttttatttaggacatttaaaagtgaatattggcaaacctcacttaaccagtgaagagacattggtatgatctgtaaatcaacattaaagaatggtcattgacagtagtgctgccatgaaaactcttggggccccgtacgactgaatagttggggccctcctctgcttgttactggcacagcaggccctttttaagctccacaagggcccaaaatagtgccttgcctgcctcagtgttgggaggggggggggggaaatataaaagaaaaattgctgtccagggtcccaagcctaaaatttcctgtttccaccttatggcagtcctaagaagctttgtagcaaactaactttatccaagagggtggggaaagtatcctttgtaaatatatcatggttgtttggtgcttttaccttgtgaaaagtctcatagtggtgaactgacagctggtttatttttctataagtaatatacagtaagtgtttttacctcagtggcttcttggaggccgtttggtatcttacatagacctttgtagcagttttacgtgcaaatatttttaaatacaagtacatctagcacccaagctactgttatctggacattgcttgaaataatgggaactttttactgtatattattgagtacattcattgaattaaacagttccttttgttgtttacttagatatttatatgatattgcctaatattaagccatccaattgcagaccttccaaacaggtataatagaagtatccacagaattacattgtatagtattagtattttggctctgtcagagcactgaatgtattttcaggttaatgacaacattccaaatcaagagagagccattcatgtgcacaatggtgcttttaggaatcctgttttatctgcaccgtgaatttgtacatagcattgtcttttgaagcttgtggaaaatatttagccctgggcataagtagtacagcaaataactaaaatgtcaatacaataatggaactcccagaaatggaagacataattcagtgcataaatgatttagccacatgtttatttaggaaaagaccaagctttcatatatgctaaaatccacaacgctgaccatttctgttaccaatagggccaaatgacattttgatacagttttgatacatttgagactataaaactgggcagaacacagtgtcatcgtcgtggcccccccccccccctgcttattgcataccagctgtttcagccaccaaaaactgttcccaccaccctgcaggttaggtgcaggcaacaggatacatgcgggctgtggcccatcaggatattcctggtgtcttgctagcccagtctgactctggcaggacagaaaatgccatttctcagaggttgcctcttggctagaaatgccttttggtcaaattaaaaaaactacatattatcaattaaaaaaactgatgaatctttaaaaaaaaaaaaaaa

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