LOCUS       NM_001016758            1743 bp    mRNA    linear   VRT 30-JUN-2020
DEFINITION  Xenopus tropicalis centrosomal protein 43 (cep43), mRNA.
ACCESSION   NM_001016758
VERSION     NM_001016758.2
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR855777.2.
            
            On Oct 14, 2005 this sequence version replaced NM_001016758.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR855777.2 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="5"
                     /map="5"
     gene            1..1743
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /note="centrosomal protein 43"
                     /db_xref="GeneID:549512"
                     /db_xref="Xenbase:XB-GENE-5752647"
     exon            1..167
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            168..282
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    169..171
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /note="upstream in-frame stop codon"
     CDS             199..1494
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /note="FGFR1 oncogene partner"
                     /codon_start=1
                     /product="centrosomal protein 43"
                     /protein_id="NP_001016758.1"
                     /db_xref="GeneID:549512"
                     /db_xref="Xenbase:XB-GENE-5752647"
                     /translation="

MSATEEDTELRDLLIQTLENNGILNKIKAELRSSVFLALEEQEKTQNKTPLVNEGLKKFLNTRDGRLVANLFTEFLQFFNLDFTLAVFQPEASLENGYDDRNHLAKELGIVESEGVKSGPLALELVRRCHQKDKIISGGEELSPKQLSEAQKKFDFYDKDKNGEISKDELRSLFLDLFPHFHRSMLERYVTDEFKAADKDFNNGINFHEFIGMYKRLFIHCRSVVTHDVPDIIHSPRRSLEGKANLQANYNQTDDRIEKNTLFSRESKQKLENHILTFEAKSDFNLNKLSFDNEERKTELDEDYLEGDSFFDDPIPKPEKTYGWKSDPPKHGGSVPAHATLPPLKTETSSRFGSLSTRESDRTGDEDDDYIDDFNSTSQRSDKSDVSIGEEIEEEELSVDDFIGSEKLEDLTLDHTISHTSDVADYLEDVS"

     misc_feature    340..582
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /note="FOP N terminal dimerization domain; Region:
                     FOP_dimer; pfam09398"
                     /db_xref="CDD:312785"
     misc_feature    643..843
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /note="EF-hand, calcium binding motif; A diverse
                     superfamily of calcium sensors and calcium signal
                     modulators; most examples in this alignment model have 2
                     active canonical EF hands. Ca2+ binding induces a
                     conformational change in the EF-hand motif, leading to...;
                     Region: EFh; cd00051"
                     /db_xref="CDD:238008"
     misc_feature    order(670..672,676..678,682..684,703..705,790..792,
                     796..798,802..804,823..825)
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238008"
     exon            283..336
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            337..391
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            392..480
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            481..618
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            619..675
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            676..746
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            747..808
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            809..870
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            871..954
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1169
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1282
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1325
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1419
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1710
                     /gene="cep43"
                     /gene_synonym="fgfr1op; FOP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

taatgacatgttaggcactgttgttcggctttgactgtgttaatagagtattgcatctcaatcggtggatcaaatggataccagtgagcccaaaagctaacgcaggttgttatgaatctgatattcctgaatttttgcgatgaatggaaacatttaatcagggttcgataattccataagcttctttacagagaaacaatgtctgcaacagaagaggacacagagttaagagatcttctgattcagaccctagaaaataatggcatccttaacaaaattaaggcagaactcagatcatctgtttttctggctttggaagaacaagagaaaacacagaacaagaccccacttgttaatgaaggtttgaagaaattcttaaatacgagagatggtcgtctggttgccaaccttttcacagaattccttcagtttttcaatcttgactttacattggcagtctttcaacctgaagctagtctggaaaatggatatgacgatcgtaatcatttagcaaaggagcttgggattgttgaatctgaaggtgtgaaaagtggtccactggcacttgagcttgtcagacgatgccatcaaaaagacaagattataagtgggggagaagaattatcacccaagcaactgtcggaagcacagaaaaagtttgatttctatgataaggataaaaatggtgaaattagcaaagatgaactccgatcactttttcttgatcttttcccacattttcatagaagcatgttggaaaggtacgtgactgatgaatttaaagctgcagataaggatttcaataatggtattaatttccacgaattcattgggatgtacaagcgtttgttcatccattgtagaagtgttgtaacacatgatgttcctgatattatacattccccacggaggtcattagaaggaaaggcaaatttacaagcaaattataatcagactgatgatcggattgaaaaaaatactctcttctctagagagtccaaacagaagcttgaaaaccacatattaacctttgaagccaaatcagatttcaatctaaacaagttatcctttgataatgaagagagaaaaacagaattggatgaagattatcttgaaggagattctttctttgatgatcctattccaaaaccagagaaaacatatggatggaaaagtgacccccctaagcatggtggaagtgttcctgctcatgcaactttgcctccattaaaaacagaaacaagttcccgctttggatcacttagcaccagagaatctgaccgaactggtgatgaagatgatgactacattgatgatttcaacagcaccagtcagcggtcagataaaagtgacgttagtattggtgaggaaatagaagaagaagaattatctgtagatgatttcattggtagtgaaaagcttgaagaccttacattggatcacactatatcacacactagtgatgtggcagattatttggaagatgtttcatagaagagagaaagcaaaattcatgacattttgaaatgtttatttgggtatcttgatcagatgtatttccagaacttcatacggacctattgagtttagcttatggcactgatcatgttgaactttccataaggttcacattcaaattataggaggtactgtaactcagactgtaattatattgtattttctttttaaataaaataaccatgtgctggacaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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