LOCUS       NM_080694               2553 bp    mRNA    linear   ROD 01-MAY-2025
DEFINITION  Rattus norvegicus calcium voltage-gated channel auxiliary subunit
            gamma 6 (Cacng6), mRNA.
ACCESSION   NM_080694
VERSION     NM_080694.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2553)
  AUTHORS   Yang,L., Katchman,A., Morrow,J.P., Doshi,D. and Marx,S.O.
  TITLE     Cardiac L-type calcium channel (Cav1.2) associates with gamma
            subunits
  JOURNAL   FASEB J 25 (3), 928-936 (2011)
   PUBMED   21127204
REFERENCE   2  (bases 1 to 2553)
  AUTHORS   Lee,J.S., Kim,J.H., Bae,J.S., Kim,J.Y., Park,T.J., Pasaje,C.F.,
            Park,B.L., Cheong,H.S., Uh,S.T., Park,J.S., Jang,A.S., Kim,M.K.,
            Choi,I.S., Park,C.S. and Shin,H.D.
  TITLE     Association of CACNG6 polymorphisms with aspirin-intolerance
            asthmatics in a Korean population
  JOURNAL   BMC Med Genet 11, 138 (2010)
   PUBMED   20860846
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2553)
  AUTHORS   Chu,P.J., Robertson,H.M. and Best,P.M.
  TITLE     Calcium channel gamma subunits provide insights into the evolution
            of this gene family
  JOURNAL   Gene 280 (1-2), 37-48 (2001)
   PUBMED   11738816
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Oct 7, 2022 this sequence version replaced NM_080694.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.608.1, SRR26643289.815.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760475
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1379              JAXUCZ010000001.1  74661375-74662753   c
            1380-1454           JAXUCZ010000001.1  74656073-74656147   c
            1455-1592           JAXUCZ010000001.1  74654321-74654458   c
            1593-2553           JAXUCZ010000001.1  74648342-74649302   c
FEATURES             Location/Qualifiers
     source          1..2553
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..2553
                     /gene="Cacng6"
                     /note="calcium voltage-gated channel auxiliary subunit
                     gamma 6"
                     /db_xref="GeneID:140727"
                     /db_xref="RGD:628806"
     exon            1..1379
                     /gene="Cacng6"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    1025..1027
                     /gene="Cacng6"
                     /note="upstream in-frame stop codon"
     CDS             1049..1831
                     /gene="Cacng6"
                     /note="neuronal voltage-gated calcium channel gamma-6
                     subunit; calcium channel, voltage-dependent, gamma subunit
                     6"
                     /codon_start=1
                     /product="voltage-dependent calcium channel gamma-6
                     subunit"
                     /protein_id="NP_542425.1"
                     /db_xref="GeneID:140727"
                     /db_xref="RGD:628806"
                     /translation="

MMWSNFFMQEEDRRRTAVGRRRAQEQQNLGLTPEREGKIKLGLLVAIVGATLAVLAVGTEFWVELNTYKTNGSAVCEAAHLGLWKVCIKRLWQADVPAGRETCGPAELPGEANCTYFKFFTTGENAHIFQRTTKKEVNLAAAVIAVLGLTAMALGCLCVIMVLSKGAEFLLRLGAVCFGLSGLLLFVSLEVFRHSVRALLQGVNPETPPAPRLAYEYSWSLGCGVGAGLILLLGGVCFLLLTLPSWPWRSLCPKRGGPTA"

     misc_feature    1175..1237
                     /gene="Cacng6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VHW7.1);
                     transmembrane region"
     misc_feature    1187..1717
                     /gene="Cacng6"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
     misc_feature    1475..1537
                     /gene="Cacng6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VHW7.1);
                     transmembrane region"
     misc_feature    1553..1615
                     /gene="Cacng6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VHW7.1);
                     transmembrane region"
     misc_feature    1709..1771
                     /gene="Cacng6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VHW7.1);
                     transmembrane region"
     exon            1380..1454
                     /gene="Cacng6"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1592
                     /gene="Cacng6"
                     /inference="alignment:Splign:2.1.0"
     exon            1593..2553
                     /gene="Cacng6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gactgggtagtggcgagcaaagccggacgcttcggaggcatcgcggagctggggccgtcgcggcgcagaggcaggagagctcaagggacccgtgccggggagacccgggtgggaagcccaaagggagcgcgggaccccgagctgagtctggagcgatcctggccgagcaggccttgggagcctgggggagggggagccgagtgactgcagacagactgactgagagtccctttccaagccctgtgtcccccagggtatttattttgccctggttttctgagcctgagtgtggaccacagtgccttgatctaagccctgtcctgactacaggttttcctcctgggccctcagagtggcccccggcctctttttctggacctcactgtgattctcagccactgtgggagacctggactcttttctgagcagttcctggcttgcctatactccctcgaattccattggggccccgaattaactgtgaatactggaggattctccttgcctttcagacttggagagatatcaaactttacctgtgaaatcccaattctaactcttgtattgcccaaaagtgtactgatttctcctttctcaaagtctgagcctgaagaaacttaaactatctcctcaaacacatgaaagacctcagcttccctctttgggaaaactctgaggcttactggagaccccatcagcagcctatagagactggacaagttttccccctgggttcttcagtcttcctcttgggtccgtaaacttcagagtagcctagcttttttcctaggcctcacctgtgccaacttcatgtgcacaagccctggcggcatccttaggccaagactatagttagtttctcttctcaggggcagaggcctccactcttgcatttcgggttcagctttttctcattcccaatctgattgacactgaggccactacttcctttgaaagtgcaggccctgctccctgccccttaagacccctctgcacgggtctttctgactccttgaagctctcctgagccccagccgatcccatcatcatgatgtggtctaacttcttcatgcaagaggaagaccgtcgtcggacggctgtgggccggcgtcgtgcccaagaacagcagaatctcggcttgactccggagcgagagggcaagatcaagctggggttgctggtggctatcgtgggtgccactctggctgtgctagctgtgggcaccgagttctgggtggaactcaatacatacaagaccaacggcagcgccgtctgtgaggccgcccatttggggctgtggaaggtgtgcatcaagcgactgtggcaggcggatgtacccgcgggcagggagacctgtggcccagctgagctgccaggagaagcaaactgcacctacttcaagttcttcaccacgggggaaaatgcgcacatcttccagagaaccaccaagaaagaggtaaacctggcagctgctgtgatagctgtgctgggcctgacagccatggccttgggctgcctctgtgtcatcatggtgctcagtaaaggtgcagagttcctgctccgcttgggagctgtctgctttggcctctcaggcctgctgctctttgtcagcctggaggtgttccggcattccgtcagagccctgctgcagggggtcaaccctgagacccctccagctccacgcctggcctatgagtattcctggtccctaggctgtggtgtgggcgctggtctaatcctgctgctggggggagtctgtttcctcctgctcaccctgccttcctggccctggaggtcactgtgccccaagcggggtggcccaactgcctagagcgctggcctgctttctgaaggcatctgccaaccctgcctcagtttccagctttctcctcaggacttttcatctctcttctagagaaactgtttttcccactctggtgggctcatttcacaaaatgtcttggtccctcatcttctctctgtaaataatgcctttgggggtgtggggaatggctcagtaagtaaatcgcttgctgagcaagcttgaggacttggaatttgagtccccagaactcactttaaaagccagcacagtagtccatgtctataattccaatgttgggaaggcagagattagaggaaccttggagctcactgaccagttagcctagtcaattattgaggtcaggttcagtgagagaccctgtctcaaacaataaggcaggagcaacaaaggaagatgcctgatgctaaactctgacacacacacacacacacacacacacacacacacacacacacacacaccacagtagttgaatttgggttgcttgaggtaggatgggaagttccctggggaaacttctagggatccgatgggagatggatgggtgaaagggctggggtcccagaaggatttgggagctttctttccaattcctcgctgatccacggaatggagagacgtcctacaactgctggatggaacaaggaagagcccgggtccaacttcactgtcatcagacttgggattaaaggtttgaagatgtgaca

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