LOCUS       NM_001108155            3326 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus kinesin family member 23 (Kif23), mRNA.
ACCESSION   NM_001108155 XM_001073723 XM_236313
VERSION     NM_001108155.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3326)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 3326)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   3  (bases 1 to 3326)
  AUTHORS   Chang,Y.C., Chen,Y.J., Wu,C.H., Wu,Y.C., Yen,T.C. and Ouyang,P.
  TITLE     Characterization of centrosomal proteins Cep55 and pericentrin in
            intercellular bridges of mouse testes
  JOURNAL   J Cell Biochem 109 (6), 1274-1285 (2010)
   PUBMED   20186884
REFERENCE   4  (bases 1 to 3326)
  AUTHORS   Kamijo,K., Ohara,N., Abe,M., Uchimura,T., Hosoya,H., Lee,J.S. and
            Miki,T.
  TITLE     Dissecting the role of Rho-mediated signaling in contractile ring
            formation
  JOURNAL   Mol Biol Cell 17 (1), 43-55 (2006)
   PUBMED   16236794
REFERENCE   5  (bases 1 to 3326)
  AUTHORS   Yuce,O., Piekny,A. and Glotzer,M.
  TITLE     An ECT2-centralspindlin complex regulates the localization and
            function of RhoA
  JOURNAL   J Cell Biol 170 (4), 571-582 (2005)
   PUBMED   16103226
REFERENCE   6  (bases 1 to 3326)
  AUTHORS   Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E.,
            Fan,J.B., Abraham,R.T. and Jiang,W.
  TITLE     Functional analysis of human microtubule-based motor proteins, the
            kinesins and dyneins, in mitosis/cytokinesis using RNA interference
  JOURNAL   Mol Biol Cell 16 (7), 3187-3199 (2005)
   PUBMED   15843429
REFERENCE   7  (bases 1 to 3326)
  AUTHORS   Tomas,A., Futter,C. and Moss,S.E.
  TITLE     Annexin 11 is required for midbody formation and completion of the
            terminal phase of cytokinesis
  JOURNAL   J Cell Biol 165 (6), 813-822 (2004)
   PUBMED   15197175
REFERENCE   8  (bases 1 to 3326)
  AUTHORS   Mishima,M., Kaitna,S. and Glotzer,M.
  TITLE     Central spindle assembly and cytokinesis require a kinesin-like
            protein/RhoGAP complex with microtubule bundling activity
  JOURNAL   Dev Cell 2 (1), 41-54 (2002)
   PUBMED   11782313
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_236313.4, XM_001073723.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3326
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..3326
                     /gene="Kif23"
                     /note="kinesin family member 23"
                     /db_xref="GeneID:315740"
                     /db_xref="RGD:1308596"
     exon            1..107
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    22..24
                     /gene="Kif23"
                     /note="upstream in-frame stop codon"
     CDS             97..2955
                     /gene="Kif23"
                     /codon_start=1
                     /product="kinesin-like protein KIF23"
                     /protein_id="NP_001101625.1"
                     /db_xref="GeneID:315740"
                     /db_xref="RGD:1308596"
                     /translation="

MKSAKAKMPRKPVIKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVVNSTTVQLHTPEGYRLNRNGDYKETQYSFKRVFGTHTTQKELFDVVASPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRFVFKSNDRNSMEIQCEVDALLERQKREAMPIPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYLYDLLEEVQFDPIKPKLPQSKMLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQMYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARPVDKAICGLTPGRRYRNLPRAGPVGDEPLTEEILQSFPPLPPCKLLDVNDEETLPRLMDALEKRHRLRQLMTEELNKQCVAFKALFKEFDNSLSNKENYIQEKLNEKEKVISGQKSEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQHQKLQREFSDKRRLEARLQGMVTETTMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPEKPERPSRDRDREKIIQRSVSPSPVPLSSNNIAQISNGQQLMSQPQLHRRSNSCSSISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKACMVSDRRRGMCWTEGREMVPTFSSEIGVQEDHCRRNTPIPVRHRRSRSAGSRWVDHKPASNVQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQESPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP"

     misc_feature    166..1398
                     /gene="Kif23"
                     /note="Kinesin motor domain, KIF23-like subgroup; Region:
                     KISc_KIF23_like; cd01368"
                     /db_xref="CDD:276819"
     misc_feature    order(193..195,430..432,439..441,445..456,1105..1107)
                     /gene="Kif23"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:276819"
     misc_feature    order(1261..1263,1270..1272,1279..1281)
                     /gene="Kif23"
                     /note="microtubule interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:276819"
     misc_feature    <1600..>2100
                     /gene="Kif23"
                     /note="DNA double-strand break repair ATPase Rad50;
                     Region: PRK03918"
                     /db_xref="CDD:235175"
     misc_feature    2482..2790
                     /gene="Kif23"
                     /note="Arf6-interacting domain of mitotic kinesin-like
                     protein 1; Region: MKLP1_Arf_bdg; pfam16540"
                     /db_xref="CDD:465166"
     exon            108..177
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            178..306
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            307..412
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            413..549
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            550..659
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            660..830
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            831..943
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1065
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1168
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1248
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1368
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1495
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1651
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1809
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1983
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2163
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2475
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2703
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2704..2786
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2787..2868
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2869..2939
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
     exon            2940..3326
                     /gene="Kif23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gcggccgcagcctccacggcttagttcccgccagccctgctccggtcggagcccgacgtcccgcgcgcgcgtcaggacagcacggagactgcggtcatgaagtcggcgaaggctaagatgcccaggaaacctgtaataaaaaaaggatctcagacaaaccttaaagatccagtgggggtgtactgtagggtgcgcccactgagctttcctgaccaagagtgctgtgtggaagtggtcaatagtacaaccgtgcagctccacacccctgagggctatcgactcaacagaaatggagactacaaggagactcagtactcatttaagcgggtatttggcacgcacaccacccagaaggagctttttgatgttgtggctagtcccttggtagatgacctcattcatggcaagaatggtcttttatttacatatggtgtgacgggaagtggaaaaacctacacaatgacagggtctccagggtccggaggcctgcttcctcgttgtttgaatatgatctttaacagcatagggtcatttcaagcaaaacgtttcgtgtttaagtctaatgataggaacagtatggaaatacagtgtgaagtcgatgccttgttagaacggcagaaaagagaagccatgcccattccaaagaccccctctagcaagcgacaagcagatccagagtttgcagatatgataaatgtacaagaattctgcaaagcagaagaagttgatgaagacagtgtctatggagtgtttgtctcttacattgaaatctataataattacctatatgatctattggaagaagtgcagtttgatcccataaagcccaaactcccacaatctaaaatgctccgagaagataagaaccacaatatgtatgttgcaggatgtacagaagtagaagtgaagtctacggaggaggcgttcgaggttttctggagaggtcagaaaaagagacgtattgctaacacccatttgaatagagagtccagtcgttcacatagcgtgttcagcattaaacttgtccaggctcccctggatgctgatggagacaatgtcttacaggaaaaagagcaaattactataagccagctgtctttggtagatcttgctggaagtgaaagaactaaccgtactaaagcagaagggaacaggttacgtgaagctggaaacattaatcagtcattgatgacactaagaacatgcatggaagtcctgagagagaaccagatgtatggaaccaacaagatggttccatatcgagattcaaagctaacgcatctattcaagaactactttgatggggaggggaaggttcggatgatcgtgtgtgtgaatcctaaggctgaagactatgaagaaagcttgcaagtcatgagatttgctgaagtaacccaagaagtggaagtagcaagaccagtagacaaggcgatatgtggcctgacaccggggagacggtacagaaacctgcctcgggcgggcccagttggagatgaacctttgactgaagagattctacagagcttcccaccactgcccccatgcaagcttttggatgtcaatgatgaggagacccttccaagactgatggatgctttggagaaacgacatcgcttacgacaactgatgactgaggagcttaacaaacaatgtgtagctttcaaagccttattcaaagaatttgacaattctctatcaaataaagaaaactacattcaggaaaaactaaatgaaaaagaaaaagtgatctcaggacagaaatcagaaatagaacgactggagaagaaaaacaaaactttggagtacaagattgagattttggagaaaacaactacgatctatgaagaagataagcgcaatctgcagcaggagcttgaaagccagcatcagaagctccagcgggagttttctgacaagcgcagattagaagccaggttgcaaggcatggtgacagaaacgacgatgaagtggcagaaggaatgtgagcgtcgggtggcagccacccagctagagatgcagaacaaactctgggtcaaagatgaaaagctcaaacagctgaaggccattgtgactgaacccaaacctgagaagccagagagaccctcccgggaccgggaccgggagaaaatcattcagagatctgtctctccttcacctgtgcctctttctagtaacaatattgctcagatttccaacggccagcaactcatgagccagccccagcttcacagacgctctaactcttgcagcagcatttctgtagcttcctgtatttcggaatgggagcagaaactgtctccattcagcacccctgtcaatgtcacctctcttgcaaggcacaggcagcaggagccaggacaaagtaaagcgtgtatggtgtcagacagaaggcgagggatgtgctggactgaaggcagggagatggtccctacattcagcagtgagataggcgtacaagaggaccactgccgcaggaacacaccaattcctgtacgacacagaaggtcccgctctgcagggagcagatgggtagatcataagcctgcctctaatgtgcaaactgagacagtcatgcagccacatgtccctcatgccatcacagtgtctgttgcaaatgaaaaggcactagctaagtgtgagaagtacatgctgacccaccaggaactggcctctgatggggagattcagactaaagtaattaagggtgatgtttataagacgagaggaggtggacagtcggttcagtttactgatattgagactttaaaacaagaatcgccaactggtagtcgaaaacgaagatcgtccacactagcacctgcccaacccgatggtacagagtctgaatggaccgatgtagaaacaaggtgttctgttgctgttgaaatgagagcaggatctcagctgggacccggatatcagcaccacgcacaacccaagcgcaagaaaccttgaactgacaaccctggtgacagaaggaggttttttgctcgtgttggtgatttacccaaagccgcaccagatgcagtgtcttgagtcgtcttgcagaagaatgtgtctagatcacattgccttttttattgtgacttttcaactgttctgaatattttctaagattttataaaaaacaaacaaatgctgctattgattagctgcaaaaaaatgcactttagacatatttaacaattaagatttttcaaagtaaaaatggtgactggccaatggttaaaccattttagggaaggtatttagaattttgtatgtatatattcactctctgacctttatatatgccaaaacagctaaataaaaaagcactcagaggc

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