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2025-01-31 08:15:57, GGRNA.v2 : RefSeq release 227 (Nov, 2024)

LOCUS       NM_001405237            5091 bp    mRNA    linear   ROD 11-SEP-2024
DEFINITION  Mus musculus histone deacetylase 5 (Hdac5), transcript variant 12,
            mRNA.
ACCESSION   NM_001405237 XM_030245586
VERSION     NM_001405237.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5091)
  AUTHORS   Li,N., Liu,T., Wang,Y.Y., Xu,T., Shi,H.J., Chang,L. and Zhu,L.J.
  TITLE     Hippocampal HDAC5-mediated histone acetylation underlies stress
            susceptibility in mice exposed to chronic social defeat stress
  JOURNAL   Neuroscience 557, 89-99 (2024)
   PUBMED   39127342
  REMARK    GeneRIF: Hippocampal HDAC5-mediated histone acetylation underlies
            stress susceptibility in mice exposed to chronic social defeat
            stress.
REFERENCE   2  (bases 1 to 5091)
  AUTHORS   Zhao,Y., Wang,H., Tang,Y., Wang,J., Wu,X., He,Z., He,Y. and Tang,Z.
  TITLE     SNHG16/miR-205/HDAC5 is involved in the progression of renal
            fibrosis
  JOURNAL   J Biochem Mol Toxicol 38 (1), e23617 (2024)
   PUBMED   38079211
  REMARK    GeneRIF: SNHG16/miR-205/HDAC5 is involved in the progression of
            renal fibrosis.
REFERENCE   3  (bases 1 to 5091)
  AUTHORS   Zhu,C., Piao,Z. and Jin,L.
  TITLE     HDAC5 inhibition attenuates ventricular remodeling and cardiac
            dysfunction
  JOURNAL   Orphanet J Rare Dis 18 (1), 266 (2023)
   PUBMED   37667300
  REMARK    GeneRIF: HDAC5 inhibition attenuates ventricular remodeling and
            cardiac dysfunction.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5091)
  AUTHORS   Kim,S.J., Hotta-Hirashima,N., Asano,F., Kitazono,T., Iwasaki,K.,
            Nakata,S., Komiya,H., Asama,N., Matsuoka,T., Fujiyama,T., Ikkyu,A.,
            Kakizaki,M., Kanno,S., Choi,J., Kumar,D., Tsukamoto,T.,
            Elhosainy,A., Mizuno,S., Miyazaki,S., Tsuneoka,Y., Sugiyama,F.,
            Takahashi,S., Hayashi,Y., Muratani,M., Liu,Q., Miyoshi,C.,
            Yanagisawa,M. and Funato,H.
  TITLE     Kinase signalling in excitatory neurons regulates sleep quantity
            and depth
  JOURNAL   Nature 612 (7940), 512-518 (2022)
   PUBMED   36477539
REFERENCE   5  (bases 1 to 5091)
  AUTHORS   Sharma,P., Karnam,K., Mahale,A., Sedmaki,K., Krishna Venuganti,V.
            and Kulkarni,O.P.
  TITLE     HDAC5 RNA interference ameliorates acute renal injury by
            upregulating KLF2 and inhibiting NALP3 expression in a mouse model
            of oxalate nephropathy
  JOURNAL   Int Immunopharmacol 112, 109264 (2022)
   PUBMED   36183679
  REMARK    GeneRIF: HDAC5 RNA interference ameliorates acute renal injury by
            upregulating KLF2 and inhibiting NALP3 expression in a mouse model
            of oxalate nephropathy.
REFERENCE   6  (bases 1 to 5091)
  AUTHORS   Lemercier,C., Verdel,A., Galloo,B., Curtet,S., Brocard,M.P. and
            Khochbin,S.
  TITLE     mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A
            transcriptional activity
  JOURNAL   J Biol Chem 275 (20), 15594-15599 (2000)
   PUBMED   10748098
REFERENCE   7  (bases 1 to 5091)
  AUTHORS   Zhou,X., Richon,V.M., Rifkind,R.A. and Marks,P.A.
  TITLE     Identification of a transcriptional repressor related to the
            noncatalytic domain of histone deacetylases 4 and 5
  JOURNAL   Proc Natl Acad Sci U S A 97 (3), 1056-1061 (2000)
   PUBMED   10655483
REFERENCE   8  (bases 1 to 5091)
  AUTHORS   Kao,H.Y., Downes,M., Ordentlich,P. and Evans,R.M.
  TITLE     Isolation of a novel histone deacetylase reveals that class I and
            class II deacetylases promote SMRT-mediated repression
  JOURNAL   Genes Dev 14 (1), 55-66 (2000)
   PUBMED   10640276
REFERENCE   9  (bases 1 to 5091)
  AUTHORS   Grozinger,C.M., Hassig,C.A. and Schreiber,S.L.
  TITLE     Three proteins define a class of human histone deacetylases related
            to yeast Hda1p
  JOURNAL   Proc Natl Acad Sci U S A 96 (9), 4868-4873 (1999)
   PUBMED   10220385
REFERENCE   10 (bases 1 to 5091)
  AUTHORS   Verdel,A. and Khochbin,S.
  TITLE     Identification of a new family of higher eukaryotic histone
            deacetylases. Coordinate expression of differentiation-dependent
            chromatin modifiers
  JOURNAL   J Biol Chem 274 (4), 2440-2445 (1999)
   PUBMED   9891014
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL954730.15.
            
            On Apr 21, 2022 this sequence version replaced XM_030245586.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784648.803321.1,
                                           SRR7345562.2448644.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               AL954730.15        63571-63708         c
            139-360             AL954730.15        58300-58521         c
            361-432             AL954730.15        51982-52053         c
            433-692             AL954730.15        40473-40732         c
            693-834             AL954730.15        40196-40337         c
            835-949             AL954730.15        39988-40102         c
            950-1080            AL954730.15        39356-39486         c
            1081-1227           AL954730.15        39051-39197         c
            1228-1340           AL954730.15        38850-38962         c
            1341-1472           AL954730.15        38398-38529         c
            1473-1695           AL954730.15        37997-38219         c
            1696-1907           AL954730.15        36110-36321         c
            1908-2189           AL954730.15        35619-35900         c
            2190-2361           AL954730.15        34799-34970         c
            2362-2495           AL954730.15        33966-34099         c
            2496-2616           AL954730.15        33535-33655         c
            2617-2666           AL954730.15        33202-33251         c
            2667-2774           AL954730.15        32932-33039         c
            2775-2830           AL954730.15        32571-32626         c
            2831-2918           AL954730.15        32363-32450         c
            2919-3038           AL954730.15        31232-31351         c
            3039-3136           AL954730.15        30905-31002         c
            3137-3255           AL954730.15        30625-30743         c
            3256-3389           AL954730.15        30105-30238         c
            3390-3474           AL954730.15        29804-29888         c
            3475-3640           AL954730.15        29518-29683         c
            3641-5091           AL954730.15        27984-29434         c
FEATURES             Location/Qualifiers
     source          1..5091
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 65.82 cM"
     gene            1..5091
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="histone deacetylase 5"
                     /db_xref="GeneID:15184"
                     /db_xref="MGI:MGI:1333784"
     exon            1..138
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            139..360
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    201..203
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="upstream in-frame stop codon"
     CDS             339..3680
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /EC_number="3.5.1.98"
                     /note="isoform 10 is encoded by transcript variant 12;
                     histone deacetylase mHDA1; histone deacetylase 4"
                     /codon_start=1
                     /product="histone deacetylase 5 isoform 10"
                     /protein_id="NP_001392166.1"
                     /db_xref="GeneID:15184"
                     /db_xref="MGI:MGI:1333784"
                     /translation="
MNSPNESDGMSGREPSLEILPRTPLHSIPVAVEVKPVLPGAMPSSMGGGGGGSPSPVELRGALAGPMDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLLGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGTGPGVSSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMIPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDTSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQMQLGKILTKTGELSRQPTTHPEETEEELTEQQEALLGEGALTIPREGSTESESTQEDLEEEEEEEEEEEEDCIQVKDEDGESGPDEGPDLEESSAGYKKLFADAQQLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGSMKSPTDQPTVVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLGKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAQEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPSVNAVATLEKVIEIQSKHWSCVQRFAAGLGCSLREAQTGEKEEAETVSAMALLSVGAEQAQAVATQEHSPRPAEEPMEQEPAL"
     misc_feature    339..404
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    453..527
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    540..800
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Glutamine-rich N-terminal helical domain of HDAC5,
                     a Class IIa histone deacetylase; Region:
                     ClassIIa_HDAC5_Gln-rich-N; cd10164"
                     /db_xref="CDD:197400"
     misc_feature    order(543..548,552..557,564..566,576..578,585..587,
                     597..599,606..608,618..623,627..632,639..644,651..653,
                     663..665,672..674,684..686,702..704,714..716)
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="dimer interface A, C [polypeptide binding]; other
                     site"
                     /db_xref="CDD:197400"
     misc_feature    order(552..557,564..566,576..578,585..590,597..602,
                     606..611,618..623,627..632,639..647,651..659,663..668,
                     672..680,684..689,702..707,714..722)
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:197400"
     misc_feature    order(576..578,588..590,600..602,609..611,621..623,
                     630..632,642..647,654..659,666..668,678..680,687..689)
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="dimer interface A, D [polypeptide binding]; other
                     site"
                     /db_xref="CDD:197400"
     misc_feature    order(630..632,642..644,675..680,687..689,705..707,
                     717..722)
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="dimer interface A, B [polypeptide binding]; other
                     site"
                     /db_xref="CDD:197400"
     misc_feature    894..1151
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1083..1085
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Phosphoserine, by AMPK, CaMK1, SIK1 and PKD/PRKD1.
                     /evidence=ECO:0000269|PubMed:17468767,
                     ECO:0000269|PubMed:21454484; propagated from
                     UniProtKB/Swiss-Prot (Q9Z2V6.2); phosphorylation site"
     misc_feature    1182..1184
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Phosphothreonine, by PKC.
                     /evidence=ECO:0000250|UniProtKB:Q9UQL6; propagated from
                     UniProtKB/Swiss-Prot (Q9Z2V6.2); phosphorylation site"
     misc_feature    1752..1820
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1800..1802
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Phosphoserine, by AMPK, CaMK1, SIK1 and PKD/PRKD1.
                     /evidence=ECO:0000269|PubMed:17468767,
                     ECO:0000269|PubMed:21454484; propagated from
                     UniProtKB/Swiss-Prot (Q9Z2V6.2); phosphorylation site"
     misc_feature    1905..1907
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:Q9UQL6; propagated from
                     UniProtKB/Swiss-Prot (Q9Z2V6.2); acetylation site"
     misc_feature    1914..2171
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    2136..2138
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9UQL6; propagated from
                     UniProtKB/Swiss-Prot (Q9Z2V6.2); phosphorylation site"
     misc_feature    2286..2288
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9UQL6; propagated from
                     UniProtKB/Swiss-Prot (Q9Z2V6.2); phosphorylation site"
     misc_feature    2346..3605
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Histone deacetylase 5; Region: HDAC5; cd10007"
                     /db_xref="CDD:212531"
     misc_feature    2361..3395
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Histone deacetylase"
     misc_feature    order(2805..2810,2832..2837,2919..2921,2925..2927,
                     3201..3203,3321..3323)
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="putative active site [active]"
                     /db_xref="CDD:212531"
     misc_feature    3552..3677
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Nuclear export signal. /evidence=ECO:0000250"
     misc_feature    3600..3677
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Z2V6.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    3633..3635
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9UQL6; propagated from
                     UniProtKB/Swiss-Prot (Q9Z2V6.2); phosphorylation site"
     exon            361..432
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            433..692
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            693..834
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            835..949
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1080
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1227
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1340
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1472
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1695
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..1907
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            1908..2189
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2361
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2362..2495
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2496..2616
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2617..2666
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2667..2774
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2775..2830
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2918
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            2919..3038
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            3039..3136
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            3137..3255
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            3256..3389
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            3390..3474
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            3475..3640
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     exon            3641..5091
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3742..3747
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="hexamer: AACAAA"
     polyA_site      3762
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="major polyA site"
     regulatory      5059..5064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
                     /note="hexamer: AATAAA"
     polyA_site      5091
                     /gene="Hdac5"
                     /gene_synonym="HD5; Hdac4; mHDA1; mKIAA0600"
ORIGIN      
gttgttgttggtggcggcggcgagcggagccggaggagccgccgcaaagatggaggagccgtcgaggaggcgctgccgctgctgttgccgccgctgctgccgccgccgcccgcgaagccggagctcgagccgcagcggggatgccgttctgagtgcctgactgcctcgccccgccccgaaggatggccttggatgggcattagaggcactgcggccctgggctcgggctcctgtcccgtccgtctgtctgttatcgtctgtctctcttgacatcacagcagctccgccccctcccgtcccagcccccaacgtcagcttcctgcaggcccagagccggcatgaactctcccaacgagtcggatggcatgtcaggccgggaaccatccttggaaatcctgccacggactcctctgcacagcatccctgtggcagtggaggtgaagccggtgctgccaggagccatgcccagctccatggggggtggaggtggaggtagccccagccccgtggagcttcggggggctctggcgggccccatggaccctgcgctacgggagcagcaactgcagcaggagctcctggtcctcaagcagcagcagcagctccagaagcagctcctgttcgccgagttccagaagcagcacgaccacttgacgcggcagcacgaggtccagctgcagaagcacctcaagcagcaggagatgctggcggctaagaggcagcaggagctggagcagcagcggcagcgggagcagcagcggcaggaggagctggagaaacagcggctggagcagcagctgctcatcctgcgcaacaaggagaagagcaaagagagtgccatcgccagcaccgaggtaaagctgaggctccaggaattcctgttgtccaagtcaaaggagcccacgccaggcggcctcaaccattccctcccacagcaccccaaatgctggggagcccaccacgcttctttggaccagagttcccctccccagagcggccctcctgggacgcctccctcctacaaattgcctttgcttgggccctatgacagccgtgatgactttcccctccgtaaaacggcctcggaacccaacttaaaagtacgttcgaggctaaaacagaaggtagccgagaggagaagcagtcccctcctgcgtcgaaaggatggcactgttattagtacttttaagaagagagcagttgagatcaccggcacggggcctggggtgtcgtccgtgtgtaacagtgcgcccggctctggccccagctctcccaacagttcccacagcaccatcgctgagaacggctttactggctcagtccccaacatccccactgagatgatcccccagcaccgggccctccctctggacagttccccaaaccagttcagcctctatacgtctccttctctgcccaacatctccctagggctgcaggccactgtcactgtcaccaactcgcacctcaccgcctccccgaagctgtcaacacagcaggaggctgagaggcaggcccttcagtccctgcggcagggcggcacactgaccggcaagttcatgagcacatcctccatccctggctgcctgttgggagtggcactggagggtgacacaagcccccacgggcacgcttccctgctgcagcacgttttgctcctggagcaggcccggcaacagagcacgctcatagcagtgccgctccatgggcagtccccactggtgacgggtgaacgtgtggccaccagcatgaggacggtgggtaagctcccgaggcaccgacctctgagccgcactcagtcctccccgctgccgcagagtccccaggccctgcagcagctggtcatgcagcagcagcaccagcagttcctggagaagcagaagcagcagcagatgcagctgggcaagatccttaccaaaactggggagctgtcaaggcagcccaccactcacccggaggagacagaagaggagctgacggagcagcaggaggccttgctgggagagggggccctgaccattccccgggaaggctctacagaaagtgagagcacccaggaagacctagaagaggaggaggaggaggaggaggaggaagaggaggactgcattcaggtcaaggatgaggatggcgagagtggtcctgatgaaggccctgacttagaagagtccagtgctggttacaaaaagttgttcgcagatgcccagcagttacagcccctccaggtgtaccaggcacccctcagcctggccactgtgcctcatcaggccctgggccgcacccagtcctcacctgctgctcctgggagcatgaagagccccacagaccaacccactgtggtgaagcacctcttcaccacaggtgtggtctatgacacgttcatgctgaagcaccagtgtatgtgcggaaacacacacgtgcacccagagcacgccggccgcatccagagcatctggtcccggctgcaggaaactggtctgctcggcaagtgtgagcggatccggggtcgtaaagccacactggatgaaatccagaccgtgcactctgagtaccacaccctgctctatgggaccagcccccttaaccggcagaagctggacagcaagaagctgcttggccccatcagccagaagatgtacgccatgctgccctgtgggggcattggggtggacagtgacacggtgtggaatgagatgcactcctcaagtgccgtgcgaatggcagtgggctgcctggtggagctggccttcaaggtggctgcaggagagctcaagaatggatttgctatcatccggcccccaggacaccatgctgaggagtccacagccatgggattctgcttcttcaactccgtagccatcacagctaaactcctgcagcagaagctgagcgtgggcaaggtcctcatcgtggactgggatattcaccatggcaacggcacccagcaagcattctacaacgatccctctgtgctctacatctccctgcatcgctacgacaacgggaacttctttccaggctctggggctcctgaagaggttggtggagggccaggtgtggggtacaacgtaaatgtggcgtggacaggaggtgtggatccccccattggagatgtggaatacctgacagccttcaggacagtggtgatgcccattgcccaggagttctcacctgacgtcgtcctagtctccgctgggtttgatgctgttgaaggacatctgtctccactgggtggctattctgtcaccgccagatgttttggccacttgaccaggcagctcatgacactggctgggggccgggtggtgctggccctggagggaggccatgacttgaccgccatctgtgatgcctctgaggcctgtgtctcggctctgctcagcgtggagctgcagcccttggatgaagcagtcttgcagcaaaagcccagcgtcaatgcggttgccacactagagaaagtcatcgagatccagagcaaacactggagctgtgtacagaggtttgccgctggtctgggctgctcgctgcgggaggctcagacaggtgagaaagaggaggccgagactgtgagcgccatggccctgctttccgtgggggctgagcaggcccaggctgttgccactcaagagcacagccccaggccagcagaggagcccatggagcaggagcctgccctgtgacaccctggcccccatccctctgggcttcatcattgtgattttgtttattttttctattaaaaacaaaaagtcacacattcaacaacgtgtgccgtgtgggtctctcagcctcgcccgcctccaagctgtttcagaaccccctcccactacaagggccctgggtcagctttcgaatccattccttctatggggcattgggtgcagtacccactttgcccatgttgtatcccatacccaattccccgtactcttctaccgtggacagtgctccaggcagtactgccaactctggagctgcctgagatgggaacagtgattggtgcctggacttcagttggcttttggggaatgccttaatttgaaatctgcccctctccaccctcaggatgatgtactaccatttaagatgcagaatcgagggaaggtaggcgtccaccccaaactttcccttcctctctatctccctcaccattctgcagactctcctctttggcctcagcactgaagactcgtgcccaggatgtaggccttagacttgtggccaggcttcttgtctcttactcctgagtatcccaggagctcaaagggtaccgggtggtgtgcagcggggttagaaggggccaggaggacctgcgtatgcaggcaggttctccactttttttctattaaactctccgtcttgtgctggaccagtataaggaggggagaaggtagaccctgcatgggggcttcaggttcatgcaagcccctctgatgttctgggccagattttctccatccatcagcctgctgcaagcagaagggtcaagatccagctcccttctggagcctttttgctttgaaacctggggatcgtgaaagacagggtagatatagttctagaatagacagggccagaaccctgtctagaagccacccctgtcccccagaggtgttgggggggggggagtccagctctcagcaggaggttgttaggagctatccatcttttccagtagccttgtgtccagaggctggagcccacagacttccagtgaatgtggtctagcctgtaggaaaccaaagatgggaaatggctcctaaggggccaatttttcttcccctataccacatccccagggctcagctatctgtttccatattgtccgtatggggcctgagcagggctgagggagctggggagtcccaccactattagttttctgtgtgtttgcgtgctgtctgtatcatccttgcactgaaccagaggctgctcacctcccactctctccccgtaggctgatcttatcctgtgccaacccactcctgctttgtctccctggacatggattttagttcagtagtttgtatcccaacacatggtttttgtcttcgtgtaaataaacttatttgtggcagtgctttctgggaa
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]