LOCUS       NM_001038676            1288 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus oocyte specific homeobox 7 (Obox7), mRNA.
ACCESSION   NM_001038676 XM_892373 XM_900082 XM_911321 XM_921973
VERSION     NM_001038676.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Ji,S., Chen,F., Stein,P., Wang,J., Zhou,Z., Wang,L., Zhao,Q.,
            Lin,Z., Liu,B., Xu,K., Lai,F., Xiong,Z., Hu,X., Kong,T., Kong,F.,
            Huang,B., Wang,Q., Xu,Q., Fan,Q., Liu,L., Williams,C.J.,
            Schultz,R.M. and Xie,W.
  TITLE     OBOX regulates mouse zygotic genome activation and early
            development
  JOURNAL   Nature 620 (7976), 1047-1053 (2023)
   PUBMED   37459895
REFERENCE   2  (bases 1 to 1288)
  AUTHORS   Sha,Q.Q., Zhu,Y.Z., Li,S., Jiang,Y., Chen,L., Sun,X.H., Shen,L.,
            Ou,X.H. and Fan,H.Y.
  TITLE     Characterization of zygotic genome activation-dependent maternal
            mRNA clearance in mouse
  JOURNAL   Nucleic Acids Res 48 (2), 879-894 (2020)
   PUBMED   31777931
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099488.1.
            
            On or before Jan 9, 2006 this sequence version replaced
            XM_892373.1, XM_900082.1, XM_911321.1, XM_921973.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099488.1, DV650568.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN01164131 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 8.27 cM"
     gene            1..1288
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /note="oocyte specific homeobox 7"
                     /db_xref="GeneID:194588"
                     /db_xref="MGI:MGI:3646231"
     exon            1..73
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /inference="alignment:Splign:2.1.0"
     exon            74..335
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    101..103
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /note="upstream in-frame stop codon"
     CDS             119..775
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /codon_start=1
                     /product="oocyte-specific homeobox protein 7"
                     /protein_id="NP_001033765.1"
                     /db_xref="CCDS:CCDS39775.1"
                     /db_xref="GeneID:194588"
                     /db_xref="MGI:MGI:3646231"
                     /translation="

MAEGPSLHPKLQVASNIPIEISSQIPQELAKNLPFQMSQSPLVTPGSTMQSSLSVPERNLLQQESEGPSRQSGCMPLSDKYVNKQTGLLASRNFRKERIVYSKEQQRLLQKHFDECQYPKEKKIVELAVLIGVTKMEIKKWFKNNRAKYRQMNLQNIKQALPESNGSSKAVSESTHFPGSIPVVASDNGESICSGTFGEDSIPKFNCSQESSLYCFQA"

     misc_feature    236..349
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4KL20.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    401..577
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /note="Homeodomain; DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:238039"
     misc_feature    order(401..415,419..421,470..472,488..490,527..529,
                     533..538,545..550,554..562,566..571)
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(407..409,416..418,536..538,545..550,557..559)
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            336..535
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /inference="alignment:Splign:2.1.0"
     exon            536..1264
                     /gene="Obox7"
                     /gene_synonym="EG194588; Gm4745"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

aagggcaggtcttctgagtagaattaaaacagacataggatttagcagattacagcaaccctctggattcctggttctccagtacaggaacatactccaataagttcagaacacacatatggctgaaggtccctccttgcatccaaaacttcaagtggcttcgaatatacccatagaaatcagttcccaaatacctcaagaactggcaaagaacttaccttttcaaatgagtcagagtcccctagtgaccccaggaagtacaatgcaatcaagtctttcagtccctgaaaggaacctacttcagcaagagtctgaaggaccatcaagacaatcaggttgtatgccactgtcagataaatatgtaaacaaacaaactggccttttggcttcaagaaattttcgaaaagaacgcattgtgtactccaaagaacagcagcgcctgctgcaaaaacattttgatgagtgccagtacccaaaggagaagaaaattgtggagctggctgtattgattggtgttacaaagatggagatcaagaaatggttcaagaacaaccgagctaagtacaggcagatgaacctccagaatattaaacaagcactgccagagtcaaatggaagctctaaagcggtttctgagtcaacccattttcctggttccatacctgttgttgcctctgacaatggagagtccatctgttcaggcacatttggtgaggattccattcccaaattcaactgcagccaggaatcttccctgtattgttttcaggcctgagatagggacatgtgttgtccgcaagaataccaagaatacctgcttgatggccatgcccctgttacagcttggaactctggtcaatcagcagcagttgaatatcagactgacttagcagtagctgaagctccagtcggcctggcatatgccgcccaagccccagaggatgctcacaattcaggtccatctgcagacaagctctggaaaaggatccttgaatacttttgacatatcagatgactggcttactctgagaaacccctccactccagcttacacctctcagttccttgacgagtccaggccttatggccaagaagaagtgtgttttacacaccattattctcagtatttggagaaataaccagtcttatctgtagaagcatcataccacagtgtagtgcgattgttttagtcagtttagctattaattttttttattgttagagaatatgttcattaaataaaaggagaaaatagtaaatttcaaaaaaaaaaaaaaaaaaaaaaaaa

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