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2024-11-22 05:57:05, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       NM_022445               2439 bp    mRNA    linear   PRI 04-AUG-2024
DEFINITION  Homo sapiens thiamin pyrophosphokinase 1 (TPK1), transcript variant
            1, mRNA.
ACCESSION   NM_022445
VERSION     NM_022445.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2439)
  AUTHORS   Sahu,U., Villa,E., Reczek,C.R., Zhao,Z., O'Hara,B.P., Torno,M.D.,
            Mishra,R., Shannon,W.D., Asara,J.M., Gao,P., Shilatifard,A.,
            Chandel,N.S. and Ben-Sahra,I.
  TITLE     Pyrimidines maintain mitochondrial pyruvate oxidation to support de
            novo lipogenesis
  JOURNAL   Science 383 (6690), 1484-1492 (2024)
   PUBMED   38547260
REFERENCE   2  (bases 1 to 2439)
  AUTHORS   Jessulat,M., Amin,S., Hooshyar,M., Malty,R., Moutaoufik,M.T.,
            Zilocchi,M., Istace,Z., Phanse,S., Aoki,H., Omidi,K., Burnside,D.,
            Samanfar,B., Aly,K.A., Golshani,A. and Babu,M.
  TITLE     The conserved Tpk1 regulates non-homologous end joining
            double-strand break repair by phosphorylation of Nej1, a homolog of
            the human XLF
  JOURNAL   Nucleic Acids Res 49 (14), 8145-8160 (2021)
   PUBMED   34244791
  REMARK    GeneRIF: The conserved Tpk1 regulates non-homologous end joining
            double-strand break repair by phosphorylation of Nej1, a homolog of
            the human XLF.
REFERENCE   3  (bases 1 to 2439)
  AUTHORS   Au,L.W.C., Lee,H.H.C., Sheng,B., Chan,K.Y., Yau,E.K.C., Mak,C.M.,
            Chan,A.Y.W., Chan,A.Y.Y., Lau,C.K.Y., Mok,V.C.T. and Lam,C.W.
  TITLE     Movement disorders associated with thiamine pyrophosphokinase
            deficiency: Intrafamilial variability in the phenotype
  JOURNAL   Clin Neurol Neurosurg 199, 106258 (2020)
   PUBMED   33031988
  REMARK    GeneRIF: Movement disorders associated with thiamine
            pyrophosphokinase deficiency: Intrafamilial variability in the
            phenotype.
REFERENCE   4  (bases 1 to 2439)
  AUTHORS   Zhu,B., Wu,J., Chen,G., Chen,L. and Yao,Y.
  TITLE     Whole Exome Sequencing Identifies a Novel Mutation of TPK1 in a
            Chinese Family with Recurrent Ataxia
  JOURNAL   J Mol Neurosci 70 (8), 1237-1243 (2020)
   PUBMED   32361878
  REMARK    GeneRIF: Whole Exome Sequencing Identifies a Novel Mutation of TPK1
            in a Chinese Family with Recurrent Ataxia.
REFERENCE   5  (bases 1 to 2439)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 2439)
  AUTHORS   Nosaka,K., Onozuka,M., Nishino,H., Nishimura,H., Kawasaki,Y. and
            Ueyama,H.
  TITLE     Molecular cloning and expression of a mouse thiamin
            pyrophosphokinase cDNA
  JOURNAL   J Biol Chem 274 (48), 34129-34133 (1999)
   PUBMED   10567383
  REMARK    GeneRIF: This is the first report on the primary sequence for
            mammalian thiamin pyrophosphokinase, a protein that catalyzes the
            pyrophosphorylation of thiamin with adenosine 5'-triphosphate to
            form thiamin pyrophosphate.
REFERENCE   7  (bases 1 to 2439)
  AUTHORS   Egi,Y., Koyama,S., Shioda,T., Yamada,K. and Kawasaki,T.
  TITLE     Identification, purification and reconstitution of thiamin
            metabolizing enzymes in human red blood cells
  JOURNAL   Biochim Biophys Acta 1160 (2), 171-178 (1992)
   PUBMED   1332781
REFERENCE   8  (bases 1 to 2439)
  AUTHORS   Haas,R.H.
  TITLE     Thiamin and the brain
  JOURNAL   Annu Rev Nutr 8, 483-515 (1988)
   PUBMED   3060175
  REMARK    Review article
REFERENCE   9  (bases 1 to 2439)
  AUTHORS   Bohn,H. and Winckler,W.
  TITLE     Isolation and characterization of four new placental tissue
            proteins (PP18, PP19, PP20, PP21)
  JOURNAL   Arch Gynecol 236 (4), 235-242 (1985)
   PUBMED   3896163
REFERENCE   10 (bases 1 to 2439)
  AUTHORS   Iwashima,A., Kinugasa,A. and Nose,Y.
  TITLE     Radiometric assay for thiamine pyrophosphokinase activity in human
            leukocytes
  JOURNAL   Acta Vitaminol Enzymol 5 (1), 41-45 (1983)
   PUBMED   6303095
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA135998.1, AF297710.1 and
            BC040555.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_022445.3.
            
            Summary: The protein encoded by this gene functions as a homodimer
            and catalyzes the conversion of thiamine to thiamine pyrophosphate,
            a cofactor for some enzymes of the glycolytic and energy production
            pathways. Defects in this gene are a cause of thiamine metabolism
            dysfunction syndrome-5. [provided by RefSeq, Apr 2017].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a). Variants 1 and 3 both encode the same isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF297710.1, AY206415.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000360057.7/ ENSP00000353165.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                DA135998.1         1-13
            14-2430             AF297710.1         1-2417
            2431-2439           BC040555.1         2807-2815
FEATURES             Location/Qualifiers
     source          1..2439
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q35"
     gene            1..2439
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /note="thiamin pyrophosphokinase 1"
                     /db_xref="GeneID:27010"
                     /db_xref="HGNC:HGNC:17358"
                     /db_xref="MIM:606370"
     exon            1..87
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       1
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1180732935"
     variation       3
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1828904104"
     variation       4
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1796797368"
     variation       5
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:550005885"
     variation       8
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189728006"
     variation       9
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1796796696"
     variation       10
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796796491"
     variation       13
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1796796202"
     variation       14..31
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="cgagcgccgagcggtcga"
                     /replace="cgagcgccgagcggtcgagcgccgagcggtcga"
                     /db_xref="dbSNP:1796794761"
     variation       17
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1175547514"
     variation       18
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1376168672"
     variation       21
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1016197357"
     variation       22
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1796795186"
     variation       25
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1467607150"
     variation       30..31
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="at"
                     /replace="ga"
                     /db_xref="dbSNP:34581809"
     variation       31
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1002298436"
     variation       32
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2152040408"
     variation       33
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796793984"
     variation       36
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:905234448"
     variation       37
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185802456"
     variation       38
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1796793084"
     variation       40
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:949955842"
     variation       42
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1173387852"
     variation       43
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1030219730"
     variation       45
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1796792069"
     variation       48
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1796791863"
     variation       50
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1585709384"
     variation       54
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1386035594"
     variation       55
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1313567278"
     variation       56
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2152040318"
     variation       57
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1346987382"
     variation       58
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:997353065"
     variation       61..62
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:1273279976"
     variation       62
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1452897808"
     variation       64
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:897657889"
     variation       65
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1796789427"
     variation       66
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796789201"
     variation       67
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1203560452"
     variation       68
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181214483"
     variation       71
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796788458"
     variation       73
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1004288399"
     variation       74
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1585709128"
     variation       75
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1053046690"
     variation       76
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1050545665"
     variation       77
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1048408593"
     variation       78
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796787526"
     variation       81..82
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="cc"
                     /replace="ccc"
                     /db_xref="dbSNP:937981133"
     variation       82
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1585709017"
     variation       83
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:932966885"
     variation       84
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1427905389"
     variation       85
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796786163"
     variation       87
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1170366502"
     exon            88..146
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       90
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1796687006"
     variation       93
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1215359628"
     variation       94
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:905233866"
     misc_feature    95..97
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /note="upstream in-frame stop codon"
     variation       96..97
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1464139097"
     variation       100
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796685894"
     variation       101
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1312584982"
     CDS             104..835
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /EC_number="2.7.6.2"
                     /note="isoform a is encoded by transcript variant 1;
                     placental protein 20; thiamine kinase; thiamine
                     diphosphokinase"
                     /codon_start=1
                     /product="thiamine pyrophosphokinase 1 isoform a"
                     /protein_id="NP_071890.2"
                     /db_xref="CCDS:CCDS5888.1"
                     /db_xref="GeneID:27010"
                     /db_xref="HGNC:HGNC:17358"
                     /db_xref="MIM:606370"
                     /translation="
MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLKVDVIVTLGGLAGRFDQIMASVNTLFQATHITPFPIIIIQEESLIYLLQPGKHRLHVDTGMEGDWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS"
     misc_feature    164..826
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /note="thiamin pyrophosphokinase; Region: PLN02714"
                     /db_xref="CDD:178316"
     variation       109
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1796685361"
     variation       113
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:766958215"
     variation       114
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:761269018"
     variation       115
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796683782"
     variation       116
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1360207392"
     variation       117
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2152038009"
     variation       119
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1300271718"
     variation       120
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1796682677"
     variation       122
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:751034120"
     variation       124
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201567119"
     variation       125
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:763434100"
     variation       127
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1796681209"
     variation       131..134
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="ccc"
                     /replace="cccc"
                     /db_xref="dbSNP:1194441329"
     variation       133
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:775787586"
     variation       134
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1378581741"
     variation       137
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1170120839"
     variation       138
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1427098734"
     variation       143
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1425413327"
     exon            147..218
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       148
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:773494136"
     variation       149
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:772219407"
     variation       151..153
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="tt"
                     /replace="ttt"
                     /db_xref="dbSNP:1384497142"
     variation       152
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1164108275"
     variation       153
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:549604070"
     variation       154
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:775457916"
     variation       156
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769583875"
     variation       157
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1458013378"
     variation       159
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:745721039"
     variation       160
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1320401289"
     variation       174
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:780833566"
     variation       175
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:756968738"
     variation       176
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1451837020"
     variation       177
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2092459668"
     variation       179
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2092459596"
     variation       186
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:746600642"
     variation       188
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:777282424"
     variation       189
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2092459385"
     variation       190
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1312832296"
     variation       191
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:150306900"
     variation       192
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1384802514"
     variation       194
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:757858211"
     variation       195
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:531486319"
     variation       200
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368467309"
     variation       201
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:77358162"
     variation       203
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760990211"
     variation       211
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375142717"
     variation       214
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1426420988"
     variation       217
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:767736177"
     variation       218
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:781502530"
     exon            219..288
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       221
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2082418263"
     variation       222
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:387906936"
     variation       224
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199780530"
     variation       226
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2082417547"
     variation       227
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:754233959"
     variation       228
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:780585860"
     variation       230
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:756505847"
     variation       231
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1014328293"
     variation       233
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1173000398"
     variation       237
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:750785597"
     variation       238
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:767900232"
     variation       239
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:551699564"
     variation       241
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138773679"
     variation       246
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2082415487"
     variation       248
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1263946777"
     variation       251
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:387906935"
     variation       252
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2082414680"
     variation       254
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:761924102"
     variation       255
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202038293"
     variation       257
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:759534507"
     variation       259
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1458425939"
     variation       260
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201086987"
     variation       261..265
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="at"
                     /replace="atgat"
                     /db_xref="dbSNP:2082412299"
     variation       261
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1339131372"
     variation       262
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1275970944"
     variation       264
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:1220025919"
     variation       267
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373745325"
     variation       269
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1044054081"
     variation       270
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760506779"
     variation       271
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370527936"
     variation       272
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200717734"
     variation       275
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1334743435"
     variation       276..285
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="gagaga"
                     /replace="gagagaga"
                     /replace="gagagagaga"
                     /db_xref="dbSNP:1563989427"
     variation       277
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1049396049"
     variation       280
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1409218641"
     variation       282
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1312560571"
     variation       283
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1341596423"
     variation       285..287
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="aaa"
                     /replace="aaaa"
                     /db_xref="dbSNP:757877655"
     variation       285
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2082409301"
     exon            289..361
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       295
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:761102584"
     variation       298
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1355733682"
     variation       299
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2078416921"
     variation       300
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1452385735"
     variation       302
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1263716441"
     variation       304
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2078416139"
     variation       305
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2078415890"
     variation       309
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:773722179"
     variation       317..319
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="ttt"
                     /db_xref="dbSNP:1322900965"
     variation       323
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:772460138"
     variation       325
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1012517862"
     variation       326
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:960990842"
     variation       331
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190902373"
     variation       332..333
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="cc"
                     /db_xref="dbSNP:2150697710"
     variation       333
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145863885"
     variation       334
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142178442"
     variation       341..345
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="aga"
                     /replace="agaga"
                     /db_xref="dbSNP:1164548288"
     variation       342
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:749455380"
     variation       345..346
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:2150697552"
     variation       348
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1383168878"
     variation       349
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:970696642"
     variation       351
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:999450743"
     variation       352
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2150697410"
     variation       353
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1316443515"
     variation       355
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1379689058"
     variation       357
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:780011692"
     variation       359
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2078411338"
     variation       361
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2078411112"
     exon            362..457
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       362
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1174570973"
     variation       366
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:775739918"
     variation       368
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2075632989"
     variation       373
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:973031491"
     variation       374..375
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="aaaataaacacaaattgt"
                     /db_xref="dbSNP:2075632166"
     variation       378
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1191650770"
     variation       380
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:961335325"
     variation       381
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2075631454"
     variation       383
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1478841378"
     variation       387
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:769874481"
     variation       396
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:746011122"
     variation       398
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:942240100"
     variation       399
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:776838304"
     variation       400
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:772204656"
     variation       403
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748032477"
     variation       405..406
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:2075629571"
     variation       408
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:778868865"
     variation       409..420
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="taa"
                     /replace="taagtgccttaa"
                     /db_xref="dbSNP:1220005801"
     variation       409
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:754758107"
     variation       412
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1255722699"
     variation       414
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:863224238"
     variation       414
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1441551399"
     variation       416
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1308654218"
     variation       425
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2075627535"
     variation       429
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:186564802"
     variation       430
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:748927409"
     variation       433
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1283537785"
     variation       436
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2151156056"
     variation       437
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2151156040"
     variation       438
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1588880738"
     variation       440
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1563779902"
     variation       445
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2075626010"
     variation       449
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:888024693"
     variation       452
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1352565065"
     variation       454
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1445682011"
     variation       457
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1045769598"
     exon            458..604
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       468
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:547285921"
     variation       469
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:863224236"
     variation       470
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1278197876"
     variation       471
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1217619180"
     variation       474
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:754068899"
     variation       478..480
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="gg"
                     /replace="ggg"
                     /db_xref="dbSNP:1339188094"
     variation       478
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:763870331"
     variation       479
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1399448036"
     variation       485
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760881424"
     variation       488
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2150829067"
     variation       490
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1454645001"
     variation       493..495
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="gcg"
                     /db_xref="dbSNP:2070003738"
     variation       494
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1358881813"
     variation       495
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:147602742"
     variation       497
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2150828894"
     variation       498
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1417315589"
     variation       500
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1267015614"
     variation       502
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:768703805"
     variation       507..508
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:2069999514"
     variation       507
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:762729038"
     variation       508
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369707518"
     variation       511
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2069998700"
     variation       512
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2069997438"
     variation       514
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:775364062"
     variation       517
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1476551905"
     variation       526
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2069995643"
     variation       528
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1265314976"
     variation       529
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:769525399"
     variation       532
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2069993680"
     variation       537
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:576168961"
     variation       538
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:770545870"
     variation       543
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1211951020"
     variation       545
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1325977316"
     variation       547
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1263990545"
     variation       548
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:746578228"
     variation       552
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:777144353"
     variation       556
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2069988406"
     variation       558
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1471756620"
     variation       562
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2069987335"
     variation       563
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1298381969"
     variation       564
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1158512516"
     variation       565
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1213824842"
     variation       566
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2150827870"
     variation       568
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1273766700"
     variation       572
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:866844744"
     variation       574
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2150827758"
     variation       578
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2069984416"
     variation       582
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:758949475"
     variation       583
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:753088448"
     variation       584
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:779361801"
     variation       585
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:755359509"
     variation       586
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:557906339"
     variation       587
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2150827494"
     variation       589
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:899357375"
     variation       591
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1037780458"
     variation       592
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1554562296"
     variation       594
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374946048"
     variation       600
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1374222446"
     variation       601
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201237707"
     variation       604
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1423121810"
     exon            605..716
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       605
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063727758"
     variation       606
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:931909509"
     variation       609
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2063727284"
     variation       612
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:922968495"
     variation       613
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371701702"
     variation       615
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2063726493"
     variation       616
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2129164924"
     variation       619
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2063726252"
     variation       620
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1223863598"
     variation       621
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1588141902"
     variation       621
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1285011402"
     variation       628
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2063725378"
     variation       631
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1196524337"
     variation       632
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063724958"
     variation       633
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1588141821"
     variation       635
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2063724454"
     variation       638
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:767663147"
     variation       640
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1014869762"
     variation       641
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1006032778"
     variation       642
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:757320791"
     variation       643
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1588141696"
     variation       646
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1207019672"
     variation       648
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1252125179"
     variation       649
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:751636131"
     variation       650
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1308919226"
     variation       651
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063722196"
     variation       652
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1238398413"
     variation       654
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:765215331"
     variation       655
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:759464081"
     variation       658
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2063721111"
     variation       661
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2129164658"
     variation       662
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1441218983"
     variation       665
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1385750838"
     variation       666
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1044799012"
     variation       669
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063720083"
     variation       675
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1387873362"
     variation       676
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2063719520"
     variation       677
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:552035224"
     variation       679
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1554523224"
     variation       686
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:766107386"
     variation       696
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:907595094"
     variation       699
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063718370"
     variation       702
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:866927997"
     variation       703
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:867275874"
     variation       705
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:982965563"
     variation       706
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2063717194"
     variation       707..708
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:2063716844"
     variation       711
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1563460241"
     variation       714
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2063716323"
     variation       715
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2063716135"
     variation       716
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:367833269"
     exon            717..2439
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /inference="alignment:Splign:2.1.0"
     variation       717
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054449244"
     variation       719
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054448943"
     variation       722
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:771280369"
     variation       723
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:747262651"
     variation       724
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:778011281"
     variation       725
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1044707304"
     variation       727
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:548115884"
     variation       728
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:778438891"
     variation       731
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2128873194"
     variation       737
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:772262824"
     variation       738
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:748289097"
     variation       742
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1348005063"
     variation       743
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1304264962"
     variation       745
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779048294"
     variation       755
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054444944"
     variation       759
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371271054"
     variation       765..770
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="acgacg"
                     /replace="acgacgacg"
                     /db_xref="dbSNP:2054442370"
     variation       765
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:750322523"
     variation       766
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113536847"
     variation       767
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368458768"
     variation       768
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:751374816"
     variation       769
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:763896351"
     variation       770
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:568804217"
     variation       771
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:764746135"
     variation       772
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:113056357"
     variation       775
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1587146519"
     variation       776
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:925712502"
     variation       777
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1243579385"
     variation       778
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:777155582"
     variation       779
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2128872988"
     variation       780
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:550639617"
     variation       782
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1273620556"
     variation       783
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1262745925"
     variation       785
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054438525"
     variation       787
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1221823907"
     variation       788
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:761078676"
     variation       790
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054437657"
     variation       791
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054437359"
     variation       793
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:773555092"
     variation       797
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054436770"
     variation       798
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1587145897"
     variation       799
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:772352353"
     variation       803
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748307256"
     variation       804
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:749295013"
     variation       807
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054434904"
     variation       809
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1431932282"
     variation       813..814
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="gg"
                     /db_xref="dbSNP:2054434304"
     variation       816
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:978505783"
     variation       818
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1404980051"
     variation       819
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1334224608"
     variation       821
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1587145339"
     variation       823
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1470674236"
     variation       827
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1429327354"
     variation       834..835
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:2054431978"
     variation       834
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1587145176"
     variation       835
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:781237117"
     variation       836..837
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="cc"
                     /replace="ccc"
                     /db_xref="dbSNP:2054431441"
     variation       838
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1426707396"
     variation       839
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1421532143"
     variation       841
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1234856365"
     variation       843
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:757245567"
     variation       844
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054430171"
     variation       848
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1482797114"
     variation       851
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:746865416"
     variation       853
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:777643659"
     variation       854
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054429162"
     variation       858
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:758136518"
     variation       861
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054428628"
     variation       863
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1263886047"
     variation       864
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:532067918"
     variation       865
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:564993869"
     variation       867
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375718551"
     variation       869
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1298362670"
     variation       871
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:754558149"
     variation       873..884
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="tctca"
                     /replace="tctcatttctca"
                     /db_xref="dbSNP:1312497823"
     variation       873
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:753267970"
     variation       874
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054426851"
     variation       876
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054426659"
     variation       881..902
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="ctcaaca"
                     /replace="ctcaacagttcattgctcaaca"
                     /db_xref="dbSNP:1278607831"
     variation       886
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:766932422"
     variation       887
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2128872649"
     variation       900
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054426025"
     variation       903
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1333771418"
     variation       904
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1358292660"
     variation       906..907
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="ac"
                     /db_xref="dbSNP:1314594548"
     variation       907
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:575636592"
     variation       908..909
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="ttc"
                     /db_xref="dbSNP:1227746352"
     variation       908
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:867075548"
     variation       910
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054424324"
     variation       911
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054424118"
     variation       912
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1288419131"
     variation       918
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:540800145"
     variation       924
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113719353"
     variation       929
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054423092"
     variation       930
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2128872566"
     variation       931
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:753388291"
     variation       932
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1277518313"
     variation       932
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:1313100970"
     variation       933
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054422235"
     variation       936
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1587143930"
     variation       938
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2128872544"
     variation       939
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:115576202"
     variation       940
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054421522"
     variation       944
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:543389713"
     variation       945
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054421117"
     variation       948
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1026508154"
     variation       950
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:146756933"
     variation       955
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054420265"
     variation       963
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1183608374"
     variation       967
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054419829"
     variation       970
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054419615"
     variation       975
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:899305639"
     variation       980
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054419217"
     variation       994
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054418969"
     variation       995..999
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="at"
                     /replace="attat"
                     /db_xref="dbSNP:1477084862"
     variation       1000
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054418466"
     variation       1004
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1587143657"
     variation       1015
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054418058"
     variation       1022
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054417816"
     variation       1026
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1773172106"
     variation       1027
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1016771607"
     variation       1031
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054417407"
     variation       1032
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1357261906"
     variation       1033
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054416944"
     variation       1034
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1170249999"
     variation       1036
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1175244358"
     variation       1037
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054416251"
     variation       1042
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054416030"
     variation       1046
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:1431866912"
     variation       1062
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2128872411"
     variation       1063
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:545388950"
     variation       1068
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1168066006"
     variation       1070
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054415112"
     variation       1071
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1308572806"
     variation       1072
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:905273590"
     variation       1073
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1433706738"
     variation       1076
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1273788267"
     variation       1083
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054413936"
     variation       1102
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054413714"
     variation       1104
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:578014433"
     variation       1111
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054413173"
     variation       1114
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054412950"
     variation       1115
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054412708"
     variation       1117
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054412489"
     variation       1118
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1236126933"
     variation       1120
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1183005235"
     variation       1123
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:553449834"
     variation       1130
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1255928723"
     variation       1131
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1207652980"
     variation       1134
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1449885724"
     variation       1140
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054410779"
     variation       1142
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054410555"
     variation       1144
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1198222590"
     variation       1145
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1342444326"
     variation       1150
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054409766"
     variation       1151
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054409525"
     variation       1154
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:948041192"
     variation       1155
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1273403752"
     variation       1160
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1224650930"
     variation       1174
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1323038931"
     variation       1178
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054408346"
     variation       1179..1183
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="aga"
                     /replace="agaga"
                     /db_xref="dbSNP:2054407703"
     variation       1180
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054408126"
     variation       1182
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:760888653"
     variation       1188
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054407481"
     variation       1189
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054407253"
     variation       1190
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1587142853"
     variation       1192
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054406607"
     variation       1195
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:992690442"
     variation       1202
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1169092666"
     variation       1203
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:533725648"
     variation       1212
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054405708"
     variation       1215
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054405497"
     variation       1218
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:895759001"
     variation       1219
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1353415609"
     variation       1221
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1403577831"
     variation       1226
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1322306095"
     variation       1227
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1309637751"
     variation       1231
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054404171"
     variation       1234
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054403977"
     variation       1236
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1331240283"
     variation       1238
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1410151297"
     variation       1243
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1053000138"
     variation       1248
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054403031"
     variation       1251
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1371440274"
     variation       1255
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054402504"
     variation       1263
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054402305"
     variation       1266
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1229629488"
     variation       1273
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054401907"
     variation       1278
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1272337308"
     variation       1279
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:1563153140"
     variation       1280
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1563153113"
     variation       1284
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054400903"
     variation       1288..1296
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="ttat"
                     /replace="ttatcttat"
                     /db_xref="dbSNP:2054399745"
     variation       1290
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1307706589"
     variation       1293
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054400331"
     variation       1295
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1354823408"
     variation       1296
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142197214"
     variation       1298
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:193069601"
     variation       1299
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:978919363"
     variation       1301..1308
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="aaaaaa"
                     /replace="aaaaaaa"
                     /replace="aaaaaaaa"
                     /replace="aaaaaaaaa"
                     /db_xref="dbSNP:569988300"
     variation       1306
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:943170146"
     variation       1308
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054398221"
     variation       1309
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:910284305"
     variation       1310
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054397787"
     variation       1314
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:987125201"
     variation       1317
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1374651930"
     variation       1318
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1587141981"
     variation       1319
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054396868"
     variation       1323
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054396642"
     variation       1325
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1005074969"
     variation       1331
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2128871915"
     variation       1332
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054396222"
     variation       1334
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1162602824"
     variation       1335
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:886170908"
     variation       1336
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054395641"
     variation       1340
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:954355523"
     variation       1342
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054395272"
     variation       1345
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2128871886"
     variation       1354
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:919525300"
     variation       1359..1362
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="tact"
                     /replace="tactact"
                     /db_xref="dbSNP:549792609"
     variation       1360
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054394827"
     variation       1361..1362
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="ct"
                     /db_xref="dbSNP:2054394414"
     variation       1366
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054394214"
     variation       1368
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1387423115"
     variation       1369
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054393796"
     variation       1373
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1435413811"
     variation       1374
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1320689430"
     variation       1375
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1416250410"
     variation       1377
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:762859688"
     variation       1378
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1285305501"
     variation       1382
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:536179132"
     variation       1391
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054391727"
     variation       1392
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1226628984"
     variation       1395
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:972257196"
     variation       1397
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1483563672"
     variation       1406
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054391052"
     variation       1407
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:963883195"
     variation       1413
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054390655"
     variation       1419
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054390450"
     variation       1421
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054390234"
     variation       1422
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1465514839"
     variation       1424
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:898630354"
     variation       1432
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054389566"
     variation       1436
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1016471913"
     variation       1438
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2128871750"
     variation       1439
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1440488141"
     variation       1442..1463
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="gaaaga"
                     /replace="gaaagagaaatgatgtgaaaga"
                     /replace="gaaagagaaatgatgtgaaagagaaatgatgtgaaaga"
                     /db_xref="dbSNP:140880403"
     variation       1442
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054388947"
     variation       1445..1449
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="aga"
                     /replace="agaga"
                     /db_xref="dbSNP:2054388487"
     variation       1446
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054388703"
     variation       1448
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2128871726"
     variation       1450
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1587141255"
     variation       1451
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1186704885"
     variation       1453
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054387826"
     variation       1463
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054387584"
     variation       1464
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200480908"
     variation       1467..1474
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="atgat"
                     /replace="atgatgat"
                     /db_xref="dbSNP:2054387111"
     variation       1474
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054386895"
     variation       1476
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:969528971"
     variation       1477
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:569140093"
     variation       1478
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:542340947"
     variation       1480
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769920534"
     variation       1486
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372934267"
     variation       1489
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054385421"
     variation       1494
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149043256"
     variation       1495
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:532154714"
     variation       1496
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1357884235"
     variation       1499
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054384800"
     variation       1502
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054384581"
     variation       1503
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2128871612"
     variation       1506
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:750793171"
     variation       1511
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1332616640"
     variation       1512
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054383858"
     variation       1515
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054383656"
     variation       1516
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1287799223"
     variation       1520..1521
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:2054383280"
     variation       1521
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:571219388"
     variation       1526
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144891862"
     variation       1529
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:979460059"
     variation       1530
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1342554427"
     variation       1533
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1199640820"
     variation       1534
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054381472"
     variation       1536
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:528675328"
     variation       1537
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:561505864"
     variation       1538
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1419155271"
     variation       1539
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054380527"
     variation       1540
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1160787694"
     variation       1542
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1375591998"
     variation       1550
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054379735"
     variation       1551
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054379566"
     variation       1555
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1389953050"
     variation       1557
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1393061188"
     variation       1561
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054378941"
     variation       1562
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054378587"
     variation       1563
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054378354"
     variation       1569
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054378148"
     variation       1570
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1294205819"
     variation       1583
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054377599"
     variation       1586
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1377713460"
     variation       1589
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:965983419"
     variation       1590
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:879453505"
     variation       1599
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61594332"
     variation       1601
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1004570203"
     variation       1606
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1392956570"
     variation       1607
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054375986"
     variation       1610
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054375749"
     variation       1614
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:552066831"
     variation       1615
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1299348504"
     variation       1616
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:553169447"
     variation       1618
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1162049059"
     variation       1620
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054374165"
     variation       1624
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054373985"
     variation       1631
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054373787"
     variation       1632
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2128871404"
     variation       1636
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:868680569"
     variation       1638
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054373355"
     variation       1640
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054373155"
     variation       1642
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1791941580"
     variation       1643
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1563151678"
     variation       1645
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:950404537"
     variation       1648
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054372506"
     variation       1649
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190747119"
     variation       1650
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054372096"
     variation       1651
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:994547737"
     variation       1657
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1202851192"
     variation       1658
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:564032610"
     variation       1663
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1480644278"
     variation       1664
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149912480"
     variation       1665
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054370775"
     variation       1666
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2128871320"
     variation       1669
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:776297285"
     variation       1671
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1432225107"
     variation       1672
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1193896809"
     variation       1675
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054369936"
     variation       1685
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:763780658"
     variation       1691
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1563151440"
     variation       1694
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:918887139"
     variation       1701
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1428257083"
     variation       1704
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1168456426"
     variation       1705
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1587139338"
     variation       1709
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1355605823"
     variation       1710
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1466785411"
     variation       1712..1731
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="catatactaaggagcctaac"
                     /replace="catatactaaggagcctaacatatactaaggagcctaac"
                     /db_xref="dbSNP:2054366128"
     variation       1713..1724
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="atatactaagga"
                     /replace="atatactaaggatatactaagga"
                     /db_xref="dbSNP:2054367139"
     variation       1713
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1563151321"
     variation       1716
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054367578"
     variation       1719
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1464012862"
     variation       1724
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054366936"
     variation       1725
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:577998625"
     variation       1728
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1291852980"
     variation       1739
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:768216849"
     variation       1740
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:963696593"
     variation       1742
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054365340"
     variation       1743
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:746662477"
     variation       1744
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373133137"
     variation       1747
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1043792720"
     variation       1753
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054364305"
     variation       1755
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1206613359"
     variation       1759
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054363884"
     variation       1760
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:541177562"
     variation       1766
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054363459"
     variation       1770
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054363225"
     variation       1771..1772
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="aa"
                     /db_xref="dbSNP:1263108448"
     variation       1775..1781
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="ttccgga"
                     /db_xref="dbSNP:2054362169"
     variation       1778
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:946799626"
     variation       1779
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:572688973"
     variation       1780
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054362359"
     variation       1783
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054361951"
     variation       1784
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:980988076"
     variation       1794
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1254518826"
     variation       1797
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1447337507"
     variation       1799
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054361372"
     variation       1804
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054361150"
     variation       1809
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139543062"
     variation       1810
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114826691"
     variation       1811
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054360648"
     variation       1812..1813
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:911825085"
     variation       1812
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:966246628"
     variation       1817
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1440406431"
     variation       1820
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:983739134"
     variation       1821
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:534836429"
     variation       1822
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:956694661"
     variation       1827
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1031045234"
     variation       1828
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1434732558"
     variation       1829
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:746309948"
     variation       1832
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1322625450"
     variation       1834
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1458288613"
     variation       1836
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1216193548"
     variation       1837
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1310524771"
     variation       1838
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1333463282"
     variation       1844
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1001263304"
     variation       1864
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1023831654"
     variation       1865
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054356275"
     variation       1870
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:575419564"
     variation       1874
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:557235995"
     variation       1879
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:904466666"
     variation       1884
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1157216192"
     variation       1890
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1467865638"
     variation       1897
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1563150536"
     variation       1898
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1242999236"
     variation       1903
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1043346362"
     variation       1906..1907
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:2054354195"
     variation       1917
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1487056858"
     variation       1922
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1007406916"
     variation       1925
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1180577936"
     variation       1929
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:538239434"
     variation       1930
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1167152040"
     variation       1933
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1409926837"
     variation       1936
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054352565"
     variation       1938
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1452174530"
     variation       1939
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054352100"
     variation       1947
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1563150360"
     variation       1950
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054351687"
     variation       1951
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:779231800"
     variation       1952
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:896620320"
     variation       1960..1963
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace=""
                     /replace="acca"
                     /db_xref="dbSNP:1160114336"
     variation       1964
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:933111321"
     variation       1966..1967
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:762680003"
     variation       1970
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:919000071"
     variation       1972
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1036058409"
     variation       1978
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:941675063"
     variation       1980
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2128870828"
     variation       1982
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369414591"
     variation       1985
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1000148680"
     variation       1986..1990
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="tct"
                     /replace="tctct"
                     /db_xref="dbSNP:902563085"
     variation       1991
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1259509302"
     variation       1994
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1043700850"
     variation       1997
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1415397116"
     variation       2002
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:946832227"
     variation       2003
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054347838"
     variation       2007..2009
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tgt"
                     /db_xref="dbSNP:2054347424"
     variation       2007
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054347636"
     variation       2009
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054347225"
     variation       2011
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1326474149"
     variation       2012
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054346821"
     variation       2013
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147369616"
     variation       2018
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2128870748"
     variation       2021
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185049418"
     variation       2022
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054346133"
     variation       2024
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369853323"
     variation       2027
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:918050523"
     variation       2041
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054345409"
     variation       2042
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1728613695"
     variation       2045
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1319050485"
     variation       2047
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:992322402"
     variation       2049
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2128870711"
     variation       2055
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1233915186"
     variation       2059
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054344572"
     variation       2060
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:944562022"
     variation       2064
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054344130"
     variation       2067
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:866319270"
     variation       2071
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054343651"
     variation       2072
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054343451"
     variation       2079
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1190718110"
     variation       2080
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1411718659"
     variation       2083
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054342793"
     variation       2094
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054342605"
     variation       2097
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054342390"
     variation       2099..2101
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tgt"
                     /db_xref="dbSNP:1299935703"
     variation       2099
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054342183"
     variation       2101..2107
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="tt"
                     /replace="ttttctt"
                     /db_xref="dbSNP:2054341293"
     variation       2103
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1249629069"
     variation       2105
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1472323686"
     variation       2109
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054341098"
     variation       2111
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054340883"
     variation       2113
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1587136736"
     variation       2114
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2128870588"
     variation       2115
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1031077827"
     variation       2120
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054340251"
     variation       2123
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054340035"
     variation       2125
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1587136687"
     variation       2132
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:979479011"
     variation       2134
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1413024155"
     variation       2136
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:968425939"
     variation       2138..2144
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="tgt"
                     /replace="tgtctgt"
                     /db_xref="dbSNP:2054338921"
     variation       2146
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054338703"
     variation       2147
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054338470"
     variation       2152
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1316892487"
     variation       2153
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2128870532"
     variation       2154..2200
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="aaggagcagtggccc"
                     /replace="aaggagcagtggcccgcgtgattgtggcatttaaggagcagtggccc"
                     /db_xref="dbSNP:2054334075"
     variation       2157
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1435194323"
     variation       2159
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2128870522"
     variation       2160
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1314649471"
     variation       2164
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1348041023"
     variation       2168
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1440867340"
     variation       2169
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1021552059"
     variation       2170
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1375027460"
     variation       2171
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1007851829"
     variation       2172
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054336491"
     variation       2175
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117837628"
     variation       2178
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1349055604"
     variation       2179
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054335826"
     variation       2180
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:111378541"
     variation       2184
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1213595822"
     variation       2186
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054335176"
     variation       2189
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1273133091"
     variation       2190
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1587136097"
     variation       2192
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1432487236"
     variation       2195
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2128870430"
     variation       2199
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054334278"
     variation       2200
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145581947"
     variation       2201
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:997292039"
     variation       2202
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:897603465"
     variation       2205
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054333227"
     variation       2208
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:969690435"
     variation       2209
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:867351901"
     variation       2216
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054332582"
     variation       2217
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054332369"
     variation       2219
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:941717501"
     variation       2220
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:887405364"
     variation       2222
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054331732"
     variation       2223
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054331524"
     variation       2234
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:754273952"
     variation       2238
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054331065"
     variation       2240
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1454570085"
     variation       2247
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:948324080"
     variation       2248
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:918162940"
     variation       2249
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1442921359"
     variation       2253
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1355789398"
     variation       2255
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054329296"
     variation       2259
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054329093"
     variation       2263
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2128870297"
     variation       2265..2267
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tat"
                     /db_xref="dbSNP:1302276470"
     variation       2267
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1433774177"
     variation       2270
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1255291669"
     variation       2276
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1208374154"
     variation       2277
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="t"
                     /replace="tgaat"
                     /db_xref="dbSNP:764466464"
     variation       2280
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054327860"
     variation       2281
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1484827347"
     variation       2290
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1339302845"
     variation       2295
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1196946457"
     variation       2298
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1275133773"
     variation       2299
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:992353661"
     variation       2300
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:567371438"
     variation       2301
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:999815954"
     variation       2302
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1253887363"
     variation       2303..2304
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="tt"
                     /replace="ttt"
                     /db_xref="dbSNP:35199404"
     variation       2303
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054326096"
     variation       2304
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054325702"
     variation       2306
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054325536"
     variation       2310
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1470032350"
     variation       2311
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1388161499"
     variation       2313
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054324925"
     variation       2316
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054324721"
     variation       2320
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2128870162"
     variation       2323
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:935466740"
     variation       2324
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1475034635"
     variation       2327
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376632615"
     variation       2330
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054323950"
     variation       2334
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:924067075"
     variation       2335
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2054323568"
     variation       2337
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1168430826"
     variation       2340..2345
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="atat"
                     /replace="atatat"
                     /db_xref="dbSNP:902760943"
     variation       2340
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2054323151"
     variation       2344
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054322960"
     variation       2368
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1403119741"
     variation       2369
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1268482749"
     variation       2375
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:979892843"
     variation       2378
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054321861"
     variation       2379
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1022276808"
     variation       2384
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:968080998"
     variation       2386
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2054321459"
     variation       2391
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1247716018"
     variation       2393
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:193167794"
     variation       2399
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1039120148"
     variation       2400
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1024482"
     variation       2404
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:944784619"
     variation       2406
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1354274188"
     variation       2409
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054319947"
     variation       2410
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:77542038"
     variation       2413..2419
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="aat"
                     /replace="aataaat"
                     /db_xref="dbSNP:2128870011"
     regulatory      2413..2418
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /note="hexamer: AATAAA"
     variation       2415
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1587134447"
     variation       2417
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1048005584"
     variation       2418
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2054319305"
     variation       2425
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054319097"
     variation       2426
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1337220383"
     variation       2429
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:929230391"
     variation       2434
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2128869991"
     variation       2437
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:563810436"
     variation       2438
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2054318205"
     polyA_site      2439
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /note="major polyA site"
     variation       2439
                     /gene="TPK1"
                     /gene_synonym="HTPK1; PP20; THMD5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1372052019"
ORIGIN      
aaggctcctcagccgagcgccgagcggtcgatcgccgtagctcccgcagcctgcgatctccagtctgtggctcctaccagccattgtaggccaataatccgttatggagcatgcctttaccccgttggagcccctgctttccactgggaatttgaagtactgccttgtaattcttaatcagcctttggacaactattttcgtcatctttggaacaaagctcttttaagagcctgtgccgatggaggtgccaaccgcttatatgatatcaccgaaggagagagagaaagctttttgcctgaattcatcaatggagactttgattctattaggcctgaagtcagagaatactatgctactaagggatgtgagctcatttcaactcctgatcaagaccacactgactttactaagtgccttaaaatgctccaaaagaagatagaagaaaaagacttaaaggttgatgtgatcgtgacactgggaggccttgctgggcgttttgaccagattatggcatctgtgaataccttgttccaagcgactcacatcactccttttccaattataataatccaagaggaatcgctgatctacctgctccaaccaggaaagcacaggttgcatgtagacactggaatggagggtgattggtgtggccttattcctgttggacagccttgtatgcaggttacaaccacaggcctcaagtggaacctcacaaatgatgtgcttgcttttggaacattggtcagtacttccaatacctacgacgggtctggtgttgtgactgtggaaactgaccacccactcctctggaccatggccatcaaaagctaacctgttgactggcatccataagtgtgcctctgccttatctcatttctcaacagttcattgctcaacaagaacgattcacctgggtttgcaagaatctaaacctctctaggggaagcccactgggtttaaagatgttagtgtttagataatacaggtaacattataaatgacagatctcaattttatagtagtgggaaagatacatgctaagaaagcaaataagctctattatattcggttggaacctaatgggaatcattccactatacaattcagtactgattattcttcttacattattaatcattccatttatcctagaaaattgtttttaatttgaatcagagaaaactgttgaggttcctcttggagtctagaacatccttaaatgtctaacaacaagggctacctctgagtaccttttagtattagttttctgtatatgatatatattatcttatactgaaaaaaaattcctttcagattggggtgttagaagtgcaccaggtcactctgaccttattactgtctttggtattgtcttaaataaatcaagaatcattgacctaattgttaaatttaaaaataggtagttagcaataggtggaaagagaaatgatgtgaaagataaatgatgattcgtggagccctactcacacattaacccccaaattcaaaagtaagaatgcaaaagtctagagggggtaacagtctgcatcatcatcacaacctaaatggagaaagctgtgcagaggaaacttaagcataaaaattgaattcgtttctgacataccttagactgaaaaactgttggttcatccagaagtgtattcatattaccagaaaatgagtttgtctatggggatacatgaacttcatatactaaggagcctaactccaaagcctgcgttctcatcccagtctgatattcacctaagtttccggacccttttccttagctgtaaaatggaagcggttggactgatggtgtctgaggttctttcccacactgaaattctaaatattgacacttagcagtcatagggctgataatacacacagttactgacttagcctaaacaacctggtgcatcgaaatgtattcacctttcttttgtaaagagaccatcttctatcttctttccacctttctctgttttatgaaaccaactgttgacatacaaaccatgattgaaggagaacctgtccaacatgttttatgtacacaaatccctatgttgctataagaaaagtgaaagtaactgttttcttcttggtgctatgacagtgtgagactcaggttgtctgtagagaatgaaaggagcagtggcccgcgtgattgtggcatttaaggagcagtggcccatgtgactgtggcattttcggcacttttcattactttctgcttgaccggaagttgaggcttagctatgtttccatcttcagtttctgaagactagttatatattccttactagaaatatattcataatatataaaagaaatatatctgtgattttaaaattttgctaccaaagaatgcatgttctgtgtgccctgaaaatgttaccagtgttaataaatggatacttatcaaaaaagaa
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]