LOCUS       NM_001397300            1858 bp    mRNA    linear   VRT 05-OCT-2024
DEFINITION  Gallus gallus nuclear factor I C (NFIC), transcript variant 2,
            mRNA.
ACCESSION   NM_001397300 XM_040653487
VERSION     NM_001397300.1
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 1858)
  AUTHORS   Tang,H., Finn,R.D. and Thomas,P.D.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 1858)
  AUTHORS   Burge,S., Kelly,E., Lonsdale,D., Mutowo-Muellenet,P., McAnulla,C.,
            Mitchell,A., Sangrador-Vegas,A., Yong,S.Y., Mulder,N. and Hunter,S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1858)
  AUTHORS   Kruse,U. and Sippel,A.E.
  TITLE     Transcription factor nuclear factor I proteins form stable homo-
            and heterodimers
  JOURNAL   FEBS Lett 348 (1), 46-50 (1994)
   PUBMED   8026582
REFERENCE   4  (bases 1 to 1858)
  AUTHORS   Kruse,U. and Sippel,A.E.
  TITLE     The genes for transcription factor nuclear factor I give rise to
            corresponding splice variants between vertebrate species
  JOURNAL   J Mol Biol 238 (5), 860-865 (1994)
   PUBMED   8182757
REFERENCE   5  (bases 1 to 1858)
  AUTHORS   Rupp,R.A., Kruse,U., Multhaup,G., Gobel,U., Beyreuther,K. and
            Sippel,A.E.
  TITLE     Chicken NFI/TGGCA proteins are encoded by at least three
            independent genes: NFI-A, NFI-B and NFI-C with homologues in
            mammalian genomes
  JOURNAL   Nucleic Acids Res 18 (9), 2607-2616 (1990)
   PUBMED   2339052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAENSK010000374.1.
            
            On Nov 7, 2021 this sequence version replaced XM_040653487.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13267660.414.1,
                                           SRR13267659.252239.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA103992290,
                                           SAMEA103992323 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 5' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               JAENSK010000374.1  1100498-1100643     c
            147-678             JAENSK010000374.1  1085048-1085579     c
            679-750             JAENSK010000374.1  1074620-1074691     c
            751-825             JAENSK010000374.1  1074277-1074351     c
            826-949             JAENSK010000374.1  1074056-1074179     c
            950-1074            JAENSK010000374.1  1073145-1073269     c
            1075-1200           JAENSK010000374.1  1070723-1070848     c
            1201-1385           JAENSK010000374.1  1070415-1070599     c
            1386-1545           JAENSK010000374.1  1067727-1067886     c
            1546-1631           JAENSK010000374.1  1066742-1066827     c
            1632-1858           JAENSK010000374.1  1063486-1063712     c
FEATURES             Location/Qualifiers
     source          1..1858
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="28"
                     /map="28"
     gene            1..1858
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="nuclear factor I C"
                     /db_xref="CGNC:49702"
                     /db_xref="GeneID:396208"
     exon            1..146
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1640
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="isoform 2 is encoded by transcript variant 2;
                     nuclear factor I-C1; nuclear factor 1 C-type; CTF; NF1-C;
                     NFI-C; NF-I/C; nuclear factor 1/C; TGGCA-binding protein;
                     nuclear factor I/C (CCAAT-binding transcription factor);
                     CCAAT-box-binding transcription factor"
                     /codon_start=1
                     /product="nuclear factor 1 C-type isoform 2"
                     /protein_id="NP_001384229.1"
                     /db_xref="CGNC:49702"
                     /db_xref="GeneID:396208"
                     /translation="

MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMTKDEERAVKDELLSEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKPSCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAGQCTNPILCIQPHHISVSVKELDLYLAYFVRERDSEQSSSPRTGIASDQEDTKPNTLDSTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPSSTGMRRTLPSTSSSGSKRHKSGSMEDDIDTSPGGEYYTSSNSPTSSSRNWTEDMEGGISPNVKTEMDKSPFNSPSPQDSSPRLSSFTQHHRPVIAVHSGIARSPHPSSTLHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPSNQQPGPLNGSGQVKVPSHYLPTQMLAPPPPPGMPRLAVSPDTKSATTTSEGGTTSPTSPTYSAPGTPPANRSFVGLGPRDPGSIYQAQAP"

     misc_feature    144..257
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="Nuclear factor I protein pre-N-terminus; Region:
                     NfI_DNAbd_pre-N; pfam10524"
                     /db_xref="CDD:463134"
     misc_feature    321..635
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="MH1 domain; Region: MH1; pfam03165"
                     /db_xref="CDD:460833"
     misc_feature    687..758
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="propagated from UniProtKB/Swiss-Prot (P17926.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    765..1631
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="CTF/NF-I family transcription modulation region;
                     Region: CTF_NFI; pfam00859"
                     /db_xref="CDD:459967"
     misc_feature    894..1163
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="propagated from UniProtKB/Swiss-Prot (P17926.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1326..1352
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /note="propagated from UniProtKB/Swiss-Prot (P17926.1);
                     Region: 9aaTAD. /evidence=ECO:0000250|UniProtKB:P08651"
     exon            147..678
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            679..750
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            751..825
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            826..949
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1074
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..1200
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1385
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1545
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1631
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1632..1858
                     /gene="NFIC"
                     /gene_synonym="CNFI-C"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agagcttcgccggagagaaagaacgcgcggactgctccagcctccgaaatgactcagtaacttttacgcctcgagtctcagctctgcaattagccactttcccagcgccgctcgggatgtattcgtctcctctctgcctgacccaggatgagttccaccccttcatcgaggcgctgctcccccacgtgcgggccttcgcctacacctggttcaacctgcaggcccgcaagcgcaagtacttcaagaagcacgagaagaggatgacgaaggacgaggagcgggcggtgaaggacgagctgctgagcgagaagcccgaggtgaagcagaaatgggcctcgcgcctcctggccaagctgcgcaaggacatccggcccgagtgccgcgaggacttcgtgctctccatcaccggcaagaagccgtcgtgctgcgtcctctccaaccccgaccagaagggcaaaatgcgccgcatcgactgcctgcgccaggccgacaaggtgtggaggctggacctggtgatggtcatcctcttcaaagggatcccgctggagagcaccgacggcgagcggctggtcaaggcgggccaatgcaccaaccccatcctctgcatccagccccaccacatcagcgtctccgtcaaagagctcgacctctacttggcctacttcgtccgcgagagagattccgagcagagcagcagtccccggacgggcatcgcctcggaccaggaggacaccaagcccaacacgctggactccacagacttccaggaaagcttcgtcacctcgggggtgttcagtgtcaccgagctcatccaggtgtcccgaacgccggtggtgacgggcacgggcccaaatttctccctgggggagctgcagggccacctggcctacgacctgaacccctccagcacgggcatgaggaggacgctgcccagcacctcctccagcgggagcaaacggcacaagtctggctccatggaggatgacatcgacacgagccccggcggcgagtactacacctcctccaactcacccacgagtagcagccgcaactggacagaggacatggaagggggcatctcccccaacgtgaagacagagatggacaaatcgcccttcaacagcccctcgccgcaggactcctcgccccgcctgagcagcttcacgcagcaccaccgtcccgtcatcgcggtgcacagcggtatcgctcgcagcccgcacccttcgtccacgctgcatttccccaccacctccattctcccccagacggcctccacctatttcccccacacggccatccggtacccgcctcatctcaacccgcaggacccactgaaagatctcgtctcgctggcctgcgacccgtccaaccagcagcccggaccgttaaatggaagtggtcaagtgaaagtgcccagccactacctgcccacgcagatgctggcaccgccacctccccccggcatgccccgcttggccgtctctcctgacaccaaatccgccacgacaacttcggagggagggacgacctcaccgacgtcacccacctactctgcaccaggcacgccccctgcgaaccgttccttcgtgggattaggaccaagggatcctgggagtatctatcaggcacaggcaccctgagaggacccccccggcgcggagcccccggcggacagcgtgcatttaccaccacctccaccacctccatcgtgacgacgacgacgacgacgacgacgacgacgacaaagcaaaaccaaacccccccctccccccctcccctcggccccccccatcccatccccggacggaaggagaagagggaaaaggaaggaaggttggaacttttcttttatgaaaag

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