2024-09-29 11:29:07, GGRNA.v2 : RefSeq release 225 (Jul, 2024)
LOCUS NM_001013611 2578 bp mRNA linear VRT 19-SEP-2023 DEFINITION Gallus gallus claudin 1 (CLDN1), mRNA. ACCESSION NM_001013611 XM_422720 VERSION NM_001013611.2 KEYWORDS RefSeq. SOURCE Gallus gallus (chicken) ORGANISM Gallus gallus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus. REFERENCE 1 (bases 1 to 2578) AUTHORS Tang H, Finn RD and Thomas PD. TITLE TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations JOURNAL Bioinformatics 35 (3), 518-520 (2019) PUBMED 30032202 REFERENCE 2 (bases 1 to 2578) AUTHORS Fishwick KJ, Neiderer TE, Jhingory S, Bronner ME and Taneyhill LA. TITLE The tight junction protein claudin-1 influences cranial neural crest cell emigration JOURNAL Mech Dev 129 (9-12), 275-283 (2012) PUBMED 22771518 REMARK GeneRIF: Claudin-1 is highly expressed in the developing neuroepithelium. REFERENCE 3 (bases 1 to 2578) AUTHORS Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C, Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S. TITLE Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation JOURNAL Database (Oxford) 2012, bar068 (2012) PUBMED 22301074 REMARK Publication Status: Online-Only REFERENCE 4 (bases 1 to 2578) AUTHORS Zhang B, Shao Y, Liu D, Yin P, Guo Y and Yuan J. TITLE Zinc prevents Salmonella enterica serovar Typhimurium-induced loss of intestinal mucosal barrier function in broiler chickens JOURNAL Avian Pathol 41 (4), 361-367 (2012) PUBMED 22834550 REMARK GeneRIF: Dietary Zn supplementation appeared to alleviate the loss of intestinal mucosal barrier function induced by S. Typhimurium challenge and the partial mechanism might be related to the increased expression of occludin and claudin-1 in broiler chickens. REFERENCE 5 (bases 1 to 2578) AUTHORS Simard A, Di Pietro E, Young CR, Plaza S and Ryan AK. TITLE Alterations in heart looping induced by overexpression of the tight junction protein Claudin-1 are dependent on its C-terminal cytoplasmic tail JOURNAL Mech Dev 123 (3), 210-227 (2006) PUBMED 16500087 REMARK GeneRIF: Taken together, our data provide evidence that appropriate expression of the tight junction protein Claudin-1 is required for normal heart looping and suggest that phosphorylation of its cytoplasmic tail is responsible for mediating this function. REFERENCE 6 (bases 1 to 2578) AUTHORS Simard A, Di Pietro E and Ryan AK. TITLE Gene expression pattern of Claudin-1 during chick embryogenesis JOURNAL Gene Expr Patterns 5 (4), 553-560 (2005) PUBMED 15749086 REMARK GeneRIF: Tissues that expressed significant levels of claudin-1 were epithelialized in chick embryo. REFERENCE 7 (bases 1 to 2578) AUTHORS Caldwell RB, Kierzek AM, Arakawa H, Bezzubov Y, Zaim J, Fiedler P, Kutter S, Blagodatski A, Kostovska D, Koter M, Plachy J, Carninci P, Hayashizaki Y and Buerstedde JM. TITLE Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis JOURNAL Genome Biol 6 (1), R6 (2005) PUBMED 15642098 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ719422.1. On Apr 3, 2005 this sequence version replaced NM_001013611.1. ##Evidence-Data-START## Transcript exon combination :: AJ719422.1, BU375537.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## FEATURES Location/Qualifiers source 1..2578 /organism="Gallus gallus" /mol_type="mRNA" /db_xref="taxon:9031" /chromosome="9" /map="9" /breed="Leghorn" gene 1..2578 /gene="CLDN1" /note="claudin 1" /db_xref="CGNC:66478" /db_xref="GeneID:424910" exon 1..301 /gene="CLDN1" /inference="alignment:Splign:2.1.0" CDS 79..714 /gene="CLDN1" /note="tight junction protein" /codon_start=1 /product="claudin-1" /protein_id="NP_001013629.1" /db_xref="CGNC:66478" /db_xref="GeneID:424910" /translation="
MASGGLQLLGFVLAFLGWMGIIISTAMPQWKMASYAGDNIVTAQALYEGLWMSCAMQSTGQIQCKVYDSLLKLEGSLQATRALMVAAILLGLVGVFVAVTGMKCMKCMEDDQVKKMRMAVFGGVIFIIAGLSALVATSWYGNRVARAFYDPFTPVNTRFEFGSALFIGWAAASLALLGGAFLCCSCPRSETSYPPSRGYPKNAPSTGKDYV"
misc_feature 91..624 /gene="CLDN1" /note="PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598" /db_xref="CDD:473919" exon 302..466 /gene="CLDN1" /inference="alignment:Splign:2.1.0" exon 467..551 /gene="CLDN1" /inference="alignment:Splign:2.1.0" exon 552..2566 /gene="CLDN1" /inference="alignment:Splign:2.1.0" ORIGIN
gtcagtgcgctgttggttgtgctcccgtgtttttcatcgcagccaacctccgcaggtgcggagcagccccgcgcagccatggccagcgggggcttgcagctcctgggcttcgtgctggccttcctcggctggatgggtatcatcatcagcaccgccatgccccagtggaagatggcatcgtacgcgggggacaacatcgtgacggcccaggcgctctacgaggggctgtggatgtcgtgcgccatgcagagcacggggcagatccagtgcaaggtgtacgactcgctgcttaagctggagggcagcctgcaggccacacgggccttgatggtggccgccatactcctgggtctggttggtgtgtttgttgctgtgacgggcatgaagtgcatgaagtgcatggaggatgaccaggtgaagaagatgcggatggctgtctttggtggcgtgatcttcatcattgcaggtctgtcagcactggtggccacgtcatggtatggcaacagagtggctcgggccttctatgaccctttcacacccgttaacaccagatttgagtttggatcagccctcttcattggctgggcagccgcttctctggcattgctggggggagcattcctctgctgctcctgcccccggagtgaaacatcctacccacccagccgaggctaccccaaaaatgccccctccacagggaaggattacgtataatgaaatgacaaagaggagccaccagcactggtagtagaagcatttggagaggacactacaatgccgctgtcctgagcagagttcagactctaggttttgccttcctcttatcccagaaatgtgtatatttttgtaatcctctttgctactggacataacttctcctttctctcccagcccgtggaggaaggctagcctaagcttgtaggtatcgccactggaaagattgaagcctccaagcttgggttaagtttagtatttgggagtaaaagggaaaatgatactgtttttagatggatgttggtgctttttttagtttttttattaaaaatagatggtaacaattcagtccccatatcccattaagttagagcccggcgtggtgtgtgtagaaatcaaagaaacactatatacaaagagaagaccaatagcttaaggggaaacataattttggggaaatgactttacaggtaggaatgtttgaagagatctaaactgtttttatactgttactggtgtcatcttcagcaccttcctttccgtgcaaagggtcagatgaaattaaattgctgtgacttaaactaaaatctgtaactgtatgcatgcgctgttggccaacagaagatgtagcgtaagacagcctggcttaactgagtgtcatcttttgacaagatctggtaagatgattgtgttacagcccttggccaatacattacagctacaacggctagcaaactcccaagcagctgcatatctccctggtgccagggaagaggtagacagaaacaatccccagttctcactgttgtctctagggctgctgcattgttccttagacactgttgctggtggttgtttcttggtgttcttagcctgactgagctcaaagctatatccccccttgtcagttacaggtcaccttttaacaagtgttgccctctctccttgagtcattccagtttgggcttagttataagttactgatctgtttgccttatgtggctaaaaaatgttaaaccaaacaatgcactgccactccctgatgtttccccatggatacctcttgtactgtcatttgaccctatctttactcttgcaaatactttcagtcatgatatgaaggcaaattccaaggaaactgacccaaaggttatagcattttctttcaatccaagctcaccaaagagggaagaaacccagcactgtaaagataaagccatcattgcatattaagtcctatatgaaaatgcagctcatgggttcccacgttttcccctgaaaccagtctgtcaccggtgtctgaccaacactggtgaggctggctggagattagtctggtgttctgaaggaggatgatatcagctttccaaggctcagctttgatttgtctaaggacagaagctgattgcttccaaccaggctttatgatggtgaatgtgttcagaggcatcaggtatctgggtttcttctgtagacaaggagagccgtgtgcacccacagcctaagtgcttcatataagccttgtacctctgtttgacctgactctgcaatgtaaatcaaagctactaaagaaaccaaccaaagcatttgcttcaggcttgatctgatgctgacctgtacttgagctgggtcacatggctcctacttctcgatggggaattgccccgtgcacagtggggccttatgagaccttgtaccttgtcttaaggggtggcagctcaggtcacactaaagagctgctgaggtctgtgcttttgtatttgcattaaccctgtgccagggagcagatgcttgtattgggaacttgtataaagtgtttaaacaatttcaataaatggatttttgtaaggaaaaaaaaaaaaaa
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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